Abstract: The present invention provides a blood purification apparatus and a blood purification circuit, by which a circuit can be shared by different modes for performing respective continuous blood purification methods, a structure of the apparatus performing the continuous blood purification methods can be simplified, and CHF, CHD, CHDF, and ECUM can be performed.

Abstract: A method of indirectly determining D/P creatinine for easily judging a peritoneal function is provided that does not require blood sampling or multiple recoveries of dialysis effluent. The method includes preparing a dialysis effluent obtained by peritoneal dialysis, measuring at least one protein marker selected from the group consisting of prealbumin, haptoglobin, alpha 1-microglobulin, C4, and total protein that are contained in the dialysis effluent, and determining D/P creatinine indirectly from the correlation equation that represents the relationship between the marker concentration and the D/P creatinine value that has been prepared beforehand. Furthermore, the PET category is determined indirectly from the D/P creatinine, which has been determined indirectly, based on the known reference value.

Abstract: [Problems] To provide a thin film-shaped porous bioabsorbable material that is a dense structure in which the pore size average is small and the pore size is uniform and which further has a large maximum stress, in particular, a porous bioabsorbable material extremely useful as an adhesion preventing material.

Abstract: A tube clamp includes a housing 1 that has an inner cavity 2 longitudinally passing through the housing 1 and an upper window 3, and a roller 4 that is mounted in the housing with its cylindrical surface positioned at the upper window and is movable longitudinally in the inner cavity. A pair of guide grooves 6 is formed along the upper window and guides a roller shaft 5. A distance between a bottom face 7 of the inner cavity and the guide grooves is smaller in a pinching region 7b than in an open region 7a. When the roller is positioned in the pinching region, a tube 11 is closed between the roller and the bottom face, and when the roller is positioned in the open region, the flow path in the tube is opened. The tube clamp further includes a slider 8 that is attached over the roller and is movable together with the roller in the inner cavity.

Abstract: The present invention provides a member (2) for catheter position verification having permeability for body fluid, characterized by including a color change indicator (2A) capable of color changing upon contact with body fluid, the color change indicator (2A) when used fitted to a medical catheter (3) to be incorporated in the body or a connection member connected to the medical catheter (3). Further, there is provided a medical catheter comprising this member for catheter position verification. The use of the above medical catheter including the member for catheter position verification realizes simpler, more reliable and safer execution of treatment and examination.

Abstract: A plate clamp where clamp resistance when a tube is slid from an insertion hole to a slit section is low, where clamping operation is easy, and where the tube being clamped at the slit section is less likely to unintentionally slide to the through-hole side. The clamp for a tube has the slit section for clamping and holding the tube at plate-like members, a tube lead-in section as a groove forwardly expanding from the forward end of the slit section, and the tube insertion hole continuously formed with the tube lead-in section. A stopper section is provided only on one side of the boundary between the tube lead-in section and the slit section.

Abstract: The configuration of the present invention includes a winged shield that has a cylindrical shield tube and wings linked to a front end side of the shield tube, a hub that is inserted into an inner bore of the shield tube so as to be movable in an axial direction, and a cannula that is mounted to a front end portion of the hub. By engaging a protrusion with a third annular groove, the hub is held with the winged shield in a state where the cannula protrudes for a predetermined length from a front end of the shield tube. In a state where an inward annular protrusion of the shield tube is engaged with a first holding portion, a tip of the cannula can be stored in the shield tube. By engaging the protrusion of a holding mechanism with a first annular groove, the hub is held with the shield tube so as not to be moved within the shield tube.

Abstract: A hollow fiber bundle that is formed by arranging a plurality of porous hollow fiber membranes 8 in one direction; a heat exchange pipe bundle that is formed by arranging and laminating a plurality of heat exchange pipes 9 in one direction crossing the hollow fiber membranes and is apposed with the hollow fiber bundle; and a potting material 10 that is filled in a region including both end parts of the hollow fiber membranes and the heat exchange pipes and forms a blood channel extending across the hollow fiber membranes and the heat exchange pipes are provided. The housing includes: blood ports 3a, 3b that face both ends of the blood channel; gas headers 4a, 4b that form gas ports 5a, 5b facing both ends of the hollow fiber bundle; and heat exchange headers 6a, 6b that form heat exchange liquid ports 7a, 7b facing both ends of the heat exchange pipe bundle.

Abstract: [Problems]To provide a material for producing a bioabsorbable material in which it is easy to remove a metal zinc catalyst from a bioabsorbable polymer such as a polymer of lactide or a polymer of lactide and caprolactone and it is easy to recycle the removed powdery metal zinc catalyst, and to provide a bioabsorbable material produced from the material for producing a bioabsorbable material. [Means for Solving Problems]A material for producing a bioabsorbable material including a three-dimensionally shaped metal zinc polymerization catalyst and a bioabsorbable polymer such as a polymer of lactide or a polymer of lactide and caprolactone; and a process for producing a material for producing a bioabsorbable material, characterized in that in the process for producing a bioabsorbable polymer by polymerization, a three-dimensionally shaped metal zinc catalyst is used as a polymerization catalyst.

Abstract: A wire is folded at the central part in the longitudinal direction thereof to form a holding member including a first linear portion 17, a return portion 18, and a second linear portion 19. The first linear portion 17 is inserted through a first pipe 13 of a guide member 2 while the second linear portion 19 is inserted through a second pipe 14 thereof. A first operation part 20 and a second operation part 23 are provided at the first linear portion 17 and the second linear portion 19, respectively. The first linear portion 17 and the second linear portion 19 of the holding member 4 are protruded from the distal end of the guide tube 10 to form a loop 3. The second linear portion 19 is protruded from the distal end of the guide tube 10 longer than the first linear portion 17 to change the shape of the loop 3 and to enlarge the loop 3.

Abstract: According to the present invention, there is provided a hemodiafiltration apparatus capable of easily and efficiently removing medium to large molecule solutes at a low cost. Provided is a hemodialysis apparatus which uses a hemodialyzer accommodating a hollow yarn membrane in hemodiafiltration to cause a dialysis fluid to flow from a dialysis fluid circuit side to a blood circuit side by forceful back-filtration via the hemodialyzer, and to cause a fluid in the blood circuit to reflux to a dialysis fluid circuit side by filtration via the hemodialyzer, the hemodialysis apparatus being characterized in that a flux operation of the fluid from the dialysis fluid side to the blood circuit side by the back-filtration, and a reflux operation of the fluid from the blood circuit side to the dialysis fluid circuit side by the filtration are repeated intermittently and for at least a plurality of times.

Abstract: A communicating member for a medical container contains a plate member 4 having a first opening 5 and a second opening 6, a first connection port 15 including the first opening 5, a plug 9 that obturates the first opening 5 and a first approximately cylindrical member 19 that is in communication with the first opening 5, a second connection port 16 including the second opening 6 and a barrier member 13 that obturates the second opening 6, and a continuous wall 17 disposed on the plate member 4 on the first approximately cylindrical member 19 side and disposed upright on the plate member 4 such that the continuous wall 17 encloses the first opening 5 and the second opening 6 when the plate member is viewed from above; and the first approximately cylindrical member 19 is provided with a first communication part 20 that has an opening on the second opening 6 side.

Abstract: The present invention provides an injection device that includes: a syringe 2 including a barrel 21 including a cylindrical barrel body 21a and a nozzle 21b provided at a front end of the barrel body so as to be communicated with the barrel body, a gasket 23 slidable in the barrel, and a plunger 24 connected with the gasket and capable of being placed into and removed from the barrel through a rear end opening of the barrel; a finger flange 25 provided in the vicinity of the rear end portion of the barrel body and molded integrally with or separately from the barrel body; a holder 3 having an inner diameter that allows the barrel to be inserted in a bore of the holder, attached to the barrel, and including a spiral protrusion 31a formed on the inner surface of a portion of the holder disposed around the nozzle; and an engagement structure capable of keeping a state in which the holder is attached to the barrel and releasing the attachment.

Abstract: A hemodialysis apparatus which controls dialysis conditions. The hemodialysis treatment is carried out under dialysis conditions determined by defining the course of the chronological target blood indication level as a target control line, measuring the blood indication level at each measurement point (controlling point) in the chronological course, calculating the dialysis conditions using the measured blood indication level and the target blood indication level at the next measurement point (controlling point) of the measurement point in the hemodialysis apparatus carrying out hemodialysis treatment by controlling dialysis conditions using blood volume (BV level) or blood volume change as an indication level (hereinafter blood indication level), to attain the target blood indication level at the next measurement point. This apparatus has a simple control mechanism and has little risk of misoperation or out-of-control. An operator can easily handle it and the control can be quickly and precisely carried out.

Abstract: An indwelling needle device includes a shield tube 4a, a flexible outer needle 8 fixed at a front end of the shield tube 4a, a hub 2 movable in a lumen of the shield tube 4a, with an infusion tube 3 being attached to an end thereof, and a rigid inner needle 1 fixed at a front end part of the hub and insertable into a lumen of the outer needle. The hub is provided with a lateral penetration path 2e that penetrates to a lumen of the hub. A space 14 between an outer surface of the hub and an inner surface of the shield tube communicates with a lumen 10 of the hub via the lateral penetration path. A sealing section 2c is provided on the outer surface of the hub, at a position on a rear end side with respect to the lateral penetration path, so as to keep liquid tightness for the space between the hub and the shield tube. Engagement recesses 2b are formed by the outer peripheral surface of the hub, at side wall portions on both sides of the lateral penetration path.

Abstract: An example of the closed-type blood reservoir of the invention is furnished with an outer shell in which a space is formed within its interior, a flexible septum that is interposed between a blood storage chamber shell and a volume adjustment chamber shell and that divides the space into a blood storage chamber for storing blood and a volume adjustment chamber for storing volume adjustment liquid, a blood inlet port, a blood outlet port, and a blood storage chamber air discharge port that are provided in the blood storage chamber shell such that they are in communication with the blood storage chamber, and a volume adjustment liquid port that is provided in the volume adjustment chamber shell such that it is in communication with the volume adjustment chamber, for injecting and ejecting the volume adjustment liquid into and away from the volume adjustment chamber, wherein the blood inlet port and the blood outlet port each are provided tangentially to the inner surface of the blood storage chamber shell such

Abstract: A blood filter device includes: a housing that includes a dome 2 provided with a blood inlet, a filter retaining portion 3 that is positioned below the dome, and a bottom portion 4 provided with a blood outlet; and a filter 8 that is mounted in a cavity of the filter retaining portion and partitions a cavity of the housing into a dome side and a bottom portion side. A sheet-like filter member 8a of the filter forms a plurality of pleats, and ridgelines of the respective pleats traverse the filter retaining portion in parallel respectively.

Abstract: The medical needle device of the present invention includes: a shield 4 including a substantially cylindrical portion 4a; a tube 13; a first hub 2 that is inserted into an inner bore of the shield movably in an axial direction, whose rear end is connected with the tube 3; a rigid needle 1 that is fixed to a front end portion of the first hub; and a hub movement controlling member 14 that is attached to the shield detachably, wherein the hub movement controlling member 14 includes: a stopper portion 14a that can be inserted from the rear end side of the shield into an inner bore of the shield exsertably, and has a front end that can be in contact with the first hub in a state of reaching a movement end on the front end side of the inner bore of the shield; and a holding portion that can maintain a state where a front end of the stopper portion 14a is in contact with the first hub 2 reaching the movement end on the front end side.

Abstract: A flow control apparatus 1 including a tubular outside member 4, a tubular inside member 10 placed in the outside member 4, and a valve member 20 is used. The inside member 10 includes a through-hole 14 passing through a side wall in a thickness direction and a contact portion 11 that is in contact with the outside member 4, which are arranged in that order in a direction from one opening 16 to the other opening 17. The valve member 20 is placed in the opening 17 of the inside member 10. The valve member 20 passes only a fluid supplied at a set pressure or higher in a direction from the one opening 16 to the other opening 17. The outside member 4 is formed so as to form a gap communicating with the through hole 14 between the outside member 4 and the contact portion 11 due to elastic deformation caused by an external force. The gap forms a flow path of a fluid in combination with the through-hole 14.

Abstract: In a heat exchanger including a plurality of tubes 1 through which a first fluid passes, a housing 2 in which the tubes 1 are installed, and sealing members for sealing a second fluid that flows over surfaces of the tubes 1, the housing 2 includes an inlet 4 for introducing the second fluid therein and a first outlet 5 and second outlets 6 for discharging the second fluid, and the sealing members include a first sealing member 3a positioned on one of end sides of the tubes 1, a second sealing member 3b positioned on the other end side of the tubes 1, and a third sealing member 3c positioned between the first and second sealing members 3a and 3b. The third sealing member 3c is provided so that a gap 7 is provided between the first sealing member 3a and the third sealing member 3c while another gap 7 is provided between the second sealing member 3b and the third sealing member 3c, and that a flow path for the second fluid is formed therein. The second outlets 6 are provided so as to be connected to the gaps 7.