Abstract: In accordance with the present invention, there are provided metal oxide-based phosphor microfine particles comprising a matrix crystal made of a metal oxide and a metal element doped as an emission center into the matrix crystal, wherein the microfine particles are provided with an organic group coordinated to a surface thereof, have a small particle size as well as a high affinity to and a high dispersibility in light-transmittable resins, and are inhibited from scattering light emitted from a light source; a process for producing the metal oxide-based phosphor microfine particles; a dispersion of the metal oxide-based phosphor microfine particles; a fluorescent conversion film; a method of separating the metal oxide-based phosphor microfine particles; a fluorescent liquid; a fluorescent paste; a phosphor; a process for producing the phosphor; and a fluorescent converter.

Abstract: A device and method for optically measuring a substance in blood using the nail as an optical window are provided. A device for optically measuring a test substance in blood by using the nail as an optical window and correcting or eliminating fluctuation of a measurement value based on optical characteristics of the nail plate, comprising irradiation means applying light within a wavelength range for measuring absorption by the test substance to the nail of a subject, detection means detecting light diffused/reflected from or transmitted through the body of the subject, and processing means processing a signal obtained by the detection means to convert the signal into a concentration of the test substance.

Abstract: The present invention relates to provide a protein group binding to keratin which is the major component of body hair, or genes encoding the same, particularly to keratin-associated proteins (KAP) which bind specifically and strongly to hair keratin or genes encoding the same. The base sequence of eurochromtic region of approximately 33.5 Mb of human chromosome 21 was determined, a dot-matrix analysis of the base sequence of the long arm region of chromosome 21 (21q22.3) was carried out, homology search was made to low frequency repetitive sequences and 16 KAP genes being expressed only in hair root cells were found. Moreover, the high frequency repetitive sequences present in the sequence spanning for approximately 1 Mb between CLDN8 gene and TIAM1 gene in the long arm region of chromosome 21(21q22.11) were masked, the presence or absence of short low frequency repetitive sequence was searched, and 22 KAP genes were found. Moreover, a group of functional peptide was designed from the above mentioned KAPs.

Abstract: Subjects of the present invention are to establish a technology for separating, isolating and culturing a stem cell derived from adult tissue while retaining the in vivo properties thereof, and to provide a preventive and/or therapeutic agent for diseases which accompany tissue injury, which comprises a stem cell derived from adult tissue as an active ingredient. In order to solve the subjects, the present invention provides a stem cell derived from adult tissue which is CD45-negative and CXCR4-positive. Also, the present invention provides a preventive and/or therapeutic agent for diseases which accompany tissue injury, which comprises the stem cell as an active ingredient.

Abstract: A color type converting means 3 generates, from a primary color image, an intensity image in a hue/saturation/intensity space normalized in a cylindrical coordinate system. A region dividing means 6 analyzes the texture of the intensity image and divides the intensity image into a plurality of regions on the basis of the result of the analysis. A density conversion curve generating means 7 generates a density conversion curve for each intensity image by smoothing the histogram for each divided region. A density converting means 8 executes density conversion of the intensity image by using the smoothing a histogram of each region. A region dividing means 5 generates a primary color image by using the intensity image which is density-converted.

Abstract: The numerical analysis system of the invention analyzes the dynamical state of the compressible fluid employing Hybrid Grid Adaptation Method by Finite Volume Method. The initial grid data are created by way of free combination of tetrahedral cells, hexahedral cells and pentahedral cells. The divide-delete index is calculated according to the density of the fluid in each cell. A triangular face of the cell is divided into triangular faces and the quadrilateral face is divided into quadrilateral faces when the cell is divided. The cell is divided only when three conditions are satisfied. The first condition is that the volume of the cell is greater than the minimum volume. The second is that the dividing level of the cell is not the maximum level. The third is that the divide-delete index is greater than the dividing threshold.

Abstract: A translation template comprising an ORF region coding for a protein, a 5? untranslated region comprising a transcription promoter and a translation enhancer and locating on the 5? side of the ORF region, and a 3? end region comprising a poly-A sequence and locating on the 3? side of the ORF region, is expressed in a translation system in the presence of an agent for modifying a C-terminal of a protein, which comprises an acceptor portion having a group capable of binding to a protein through a transpeptidation reaction in a protein translation system and a modifying portion comprising a nonradioactive modifying substance linked to the acceptor portion via a nucleotide linker, to cause protein synthesis and the synthesized protein is purified. Thus, the yield of modified protein in a method of modifying C-terminal of protein is improved and detection of protein interaction based on various intermolecular interaction detection methods is realized at an improved level.

Abstract: An optical communication system is formed by connecting a base station to user stations. Each user station has a transmitting section for upstream communication. The base station has a light source which supplies transmission light used for upstream communication.

Abstract: There is provided a manipulator simplified in maintenance and operation thereof, the manipulator having the freedom of two-degree-of-freedom of rotation and gripping, and being capable of ensuring force feedback or force sensation with excellent operationability. A link mechanism 3 is provided between an operating part 1 and a working part 2. The link mechanism 3 comprises four driving rods 3a to 3d and first and second coupling members of the same structure, 41, 42 provided at opposite ends of the driving rods. First and second working members 2a, 2b move correspondingly to operations of first and second operating members 1a, 1b with the aid of the link mechanism 3. For example, provided that the first and second operating members 1a, 1b might be opened and closed, the first and second working members 2a, 2b might be opened and closed (gripping).

Abstract: A novel two-dimensional optical signal processing circuit which becomes possible only by the introduction of a concave, flat or convex reflecting structure; and a method of producing the same. Disposed on an optical wave-guiding circuit board (50) formed with an output wave-guiding path (13) and an input wave-guiding path (14) are the optical axes of the input coupling end (I) and output coupling end (U) of a coupling circuit (15) such that the optical axes pass through the same point (Q) on a reflection structure (16), the reflection structure (16) being fabricated by using a laser ablation device (30).

Abstract: A fluorescent probe for measuring magnesium ion, which can selectively form a complex with magnesium ion in aqueous system is disclosed. The fluorescent probe for measuring magnesium ion according to the present invention has the structure represented by the following Formula [I]: (wherein R1 represents a hydrogen atom, metal atom or an ester-forming group; A represents a group which forms a ring structure together with carbon atom 1 and carbon atom 2; and X is a fluorescent group which may form a condensed ring together with the ring containing the group A).

Abstract: The reformer 100 includes: an evaporating unit 102 that has a source fuel inlet 114 through which hydrocarbon-containing source fuel 202 is introduced, and is capable of evaporating a source fuel 202 introduced through the source fuel inlet 114; a catalyst containing unit 104 that is provided in the evaporating unit 102 and stores a reforming catalyst 108, which is capable of inducing a reaction for reforming the source fuel 202 into a reformed fuel having higher hydrogen amount; and a hydrogen outlet 118 that is provided on the catalyst containing unit 104 so as to communicate with the catalyst containing unit 104.

Abstract: A data receiving method and unit extracts required data from among received digital signal data, and uses a predetermined decoding key to decode the extracted data. In the method and unit, it is determined whether the decoded data is normal. If it is determined that decoding has not been normally performed, corresponding data is deleted.

Abstract: Pemphigus vulgaris (PV) is an autoimmune disease with a possible fatality of the skin and mucosae which is induced by an antibody against desmoglein 3 (Dsg3). Persistent production of anti-Dsg3 IgG can be induced by adoptively transferring spleen cells of a DSG3?/? mouse immunized with rDsg3 into an RAG2?/? immunodeficient mouse expressing Dsg3 protein. This IgG in the blood binds to the Dsg3 protein in vivo, induces the breakage of intercellular adhesion of keratinocytes and thus brings about the phenotype of pemphigus vulgaris involving the formation of blisters in the oral mucosa and the disappearance of resting hair. These effects are sustained over 6 months. By using this method, active disease model animals relating to various autoimmune diseases can be constructed.

Abstract: EMI noise in a system using a power converter with switching control is reduced in a simple configuration. The power converter 3 includes a converter 31, a smoothing capacitor 32, and an inverter 33, and receives the power from an AC power supply 1 via an AC reactor 2 and converts it into a power of an optional frequency and voltage to supply to a motor 4. Damping impedance elements 6, 7, 8 are inserted between the frame of the motor 4 and the ground 5, between the cooling fin 34 of the power converter 3 and the ground 5, and between the AC reactor 2 and the ground 5, respectively. Further, paths between the AC reactor 2 and ground 5, between the power converter 3 and ground 5, and between the motor 4 and ground 5 are insulated except that the damping impedance elements 6, 7, 8 are inserted.

Abstract: A novel human monoclonal antibody specifically recognizing cancer cells such as non-small cell lung cancer, pancreatic cancer and gastric cancer cells is produced by hybridomas which are obtained by fusing lymphocytes derived from a cancer tissue of a cancer patient with mouse myeloma cells. An anti-cancer drug is obtained by using the antibody alone or anchoring the antibody on the surface of a liposome containing a toxin or an anti-cancer drug encapsulated therein. More specifically, an anti-cancer drug is obtained by using an antibody, in which variable region of its heavy chain comprises the amino acid sequence of SEQ ID NO: 115 and variable region of the light chain comprises the amino acid sequence of SEQ ID NO: 117, alone or anchoring the antibody on the surface of a liposome containing a toxin or an anti-cancer drug encapsulated therein.

Abstract: An artificial antibody library with a super-repertory (1011 or more) is constructed by: using a cDNA library as a template, amplifying a fragment containing the CDR1 and CDR2s regions of the VH or VL region of immunoglobulin gene and a fragment containing the CDR3 region each by the PCR method; integrating the VH library and the VL library, which are little contaiminated with unexpressionable repertory and have high safety, into an nono-expression vector; transferring it into a host; and then shuffling the VH region in the VH library with the VL region in the VL library.

Abstract: A fluororesin tube body (10) of an endoscope flexible tube (1) is small in diameter and thin in wall thickness to such a degree that it is difficult to maintain its cross-sectional shape by itself when the flexible tube (1) is bent to the limit. A braid (20) woven from a plurality of flat bands (21) to form a tubular shape is disposed around the tube body (10). The mesh openings of the braid (20) are filled with filling adhesive (30), which bonds the tube body (10) and the braid (20) together. The filling adhesive (30) has enough elasticity to allow deformation of the braid (20) during the bending operation and enough adhesive strength to maintain the bond between the tube body (10) and the braid (20) even when the filling adhesive (30) is elastically deformed. Consequently, the braid (20) restricts the cross-sectional deformation of the tube body (10). Thus, the limit curvature of the flexible tube (1) can be increased.

Abstract: The present invention relates to a magnetic ring unit and a magnetic memory device; an object of the invention is to control the direction of rotation of the magnetic flux freely and with high reproducibility in a simple structure without using a thermal process such as pinning; and a magnetic ring unit is formed of a magnetic ring in eccentric ring form where the center of the inner diameter is located at a decentered position relative to the center of the outer diameter.

Abstract: A second wiring layer 362 of a multilayer wiring board constituting a power converter is provided with a first positive side direct current wiring 311p and a second positive side direct current wiring 312p constituting a direct current bus 300p. The first positive side direct current wiring 311p and the second positive side direct current wiring 312p as well as a negative side direct current wiring are provided with a bent structure for making a transmission path length on one side in a direct current transmitting direction shorter than a transmission path length on other side thereof. Line widths of the first positive side direct current wiring 311p and the second positive side direct current wiring 312p are set to a width equal to or larger than a width by which a damping factor of a noise current in the direct current transmitting direction becomes substantially a constant value.