Abstract: A cell culture medium for culturing organoid containing at lest two types of components selected from the group consisting of insulin-like growth factor 1 (IGH1), fibroblast growth factor 2 (FGF2) and epiregulin (EREG), and at least one type of component among the following components i (to III); i) Wnt agonist, ii) bone morphogenetic protein (BMP) inhibitor, and iii) transforming growth factor-? (TGIF-?) inhibitor.

Abstract: An implant installation strength evaluation method includes a step of vibrating an implant, a step of measuring time series data of the number of vibrations and vibration strengths of the implant vibrated in the vibrating step, and a step of deriving information indicating an index of an installation strength of the implant based on the time series data of the number of vibrations and vibration strengths of the implant.

Abstract: The invention provides a compound or a salt thereof capable of activating natural killer T cell, a natural killer T cell activating agent containing such a compound or a salt thereof, and a pharmaceutical composition. The compound of the invention is a compound represented by the following formula (1) or a salt thereof. It is preferable that total carbon number of the number of carbon atoms in the monovalent hydrocarbon group in R1 in the formula (1) excluding a substitutent and the number of carbon atoms in the divalent hydrocarbon group in X1 is 5 to 50. The natural killer T cell activating agent contains the aforementioned compound or a salt thereof. The pharmaceutical composition contains the aforementioned compound or a pharmacologically acceptable salt thereof.

Abstract: Provided herein are compositions and methods for the induction and/or proliferation of CD8+ T-cells. The disclosure also provides methods of treatment of diseases that can be treated by the induction and/or proliferation of CD8+ T-cells.

Abstract: Provided is a novel marker for determining sensitivity to an anti-cancer agent. The marker for determining sensitivity to an anti-cancer agent, the anti-cancer agent including oxaliplatin or a salt thereof, fluorouracil or a salt thereof, and levofolinate or a salt thereof, the marker comprising one or more substances selected from the group consisting of 2DG6P, 2MSE, CSSG, DOPM, GSSG, I4A, P2CB, 1-methyl-2-pyrrolidone, ASP, benzamide, glucaric acid, GL6P, Gly-Gly, HYPT and HYPX.

Abstract: Provided are a method and apparatus for measuring free residual chlorine concentration that is accurate and simple, which can obtain objective measurement results without using any harmful reagents, and without being affected by the potential window.

Abstract: A magnetic resonance imaging method according to an embodiment includes performing a balanced SSFP sequence, repeatedly applies an excitation RF pulse to a subject at intervals of a repetition time and applies gradient magnetic field pulses balanced such that a time integral becomes zero within each interval of the repetition time, while further applying a spin labeling gradient magnetic field for generating one or more continuous spin labels within each interval of the repetition time.

Abstract: With the aim of proving an antibacterial composition against oral bacteria and the like capable of inducing Th1 cell proliferation or activation in an intestinal tract, the present inventors have found out that bacteria that suppress colonization and the like of the oral bacteria and the like in the intestinal tract are present in an intestinal microbiota. Moreover, the present inventors have succeeded in isolating intestinal bacteria that suppress intestinal colonization and the like of oral bacteria and the like.

Abstract: In order to make advanced gait training easy and effective, an electrical spinal cord stimulator for gait training used in gait training for those who have difficulty in walking due to hemiplegia includes: first and second electrodes attached to a rehabilitant; a detector which detects a gait-related physical movement of the rehabilitant; and an electrical sensory nerve stimulation generator which generates, according to a detection result of the detector, electrical stimulation to be applied through the first and second electrodes to a nerve root of a sensory nerve which communicates with a spinal cord.

Abstract: The invention relates to a rotation information transmission apparatus where wireless communication of data of several Gbps is made possible without miniaturizing the coupler to such an extent that installation is difficult. A first substrate where a first coupler in arc form is provided in an upper portion or a lower portion and a second substrate where a second coupler in arc form of which the length of the arc is shorter than that of the first coupler in arc form is arranged in a location where coupling with the first coupler in arc form is possible are arranged so as to rotate relative to each other by fixing either the first substrate or the second substrate to a non-movable portion and fixing the other of the first substrate or the second substrate to a rotational member.

Abstract: A battery's state of charge estimation apparatus will be provided. The battery's state of charge estimation apparatus includes: a charge and discharge current detection unit; a terminal voltage detection unit; an open circuit voltage method state of charge estimation unit for estimating an open circuit voltage of the battery and an open circuit voltage method state of charge; a current integration method state of charge estimation unit for obtaining a current integration method state of charge as a state variable; and an error correction value calculation unit for calculating an error correction value for correcting the current integration method state of charge. The current integration method state of charge estimation unit corrects the current integration method state of charge by using the error correction value.

Abstract: The present invention provides an antibody that specifically binds to human aggrecanase, and inhibits enzymatic activity of the human aggrecanase. In one embodiment, aggrecanase is ADAMTS4. In one embodiment, the antibody recognizes a particular epitope in human ADAMTS4, and inhibits not only aggrecanase activity of human ADAMTS4 but also aggrecanase activity of human ADAMTS5. In addition, the present invention also provides use of said antibody in the prophylaxis or treatment of the progression of arthritis.

Abstract: An image acquisition unit configured to acquire an image representing a three-dimensional shape of a surface of a human body, a spinal-column arrangement estimation-unit configured to estimate spinal-column arrangement of the human body using accumulated data, and an angle calculation unit configured to calculate at least one of a Cobb angle and a rotation angle from the estimated spinal-column arrangement are included.

Abstract: A light-emitting device according to one embodiment includes: a substrate; a graphite thin film disposed on the substrate; and an electrode provided on a second surface of the graphite thin film on an edge portion of the graphite thin film, the second surface of the graphite thin film being opposite from a first surface of the graphite thin film, the first surface of the graphite thin film opposed to the substrate. A plurality of protrusions for supporting the graphite thin film is formed on a surface of the substrate opposed to the graphite thin film, at least over an entire region where the substrate and a portion of the graphite thin film other than the edge portion overlap each other when viewed along a thickness direction of the substrate.

Abstract: Provided herein are compositions and methods for the induction and/or proliferation of CD8+ T-cells. The disclosure also provides methods of treatment of diseases that can be treated by the induction and/or proliferation of CD8+ T-cells.

Abstract: A position/force controller includes a function-dependent force/speed distribution conversion unit that, on the basis of speed, position and force information relating to a position based on an action of an actuator and control reference information, performs a conversion to distribute control energy to at least one of speed or position energy and force energy according to a function that is being realized. A control amount calculation unit calculates at least one of a speed or position control amount and a force energy on the basis of at least one of the speed or position energy and the force energy distributed by the force/speed distribution conversion unit. An integration unit integrates speed or position control amount with force control amount and, to return an output to the actuator, performs a reverse conversion on the speed or position control amount and the force control amount and determines an input to the actuator.

Abstract: In related-art methods of differentiating pluripotent stem cells into a desired cell type, there has not been established a differentiation induction method using human ES/iPS cells and being stable and highly efficient. A method of inducing differentiation into a desired cell type within a short period of time and with high efficiency by attenuating differentiation resistance of a pluripotent stem cell to generate a pluripotent stem cell that actively proceeds to a differentiated cell type has been found, and thus the present invention has been completed.

Abstract: The present invention provides an antibody that specifically binds to human ADAM28, inhibits enzyme activity of human ADAM28, and has an activity to suppress metastasis of a cancer cell that expresses human ADAM28. The antibody of the present invention can be a human antibody.

Abstract: Media which contain 4-tryptophan or an L-tryptophan derivative at a concentration of not less than 176 ?M are useful for culturing pluripotent stem cells.

Abstract: [Problem to be Solved] To provide a device for rehabilitation capable of giving a patient who cannot express an intention to voluntarily move the body a kinesthetic illusion that the his/her own body is moving and thus achieving a high rehabilitation effect, a rehabilitation system including it, a program for rehabilitation, and a rehabilitation method. [Solution] The device for rehabilitation includes: a biological signal acquisition unit 71 that acquires biological signals from a patient imparted with illusory stimulation for inducing a kinesthetic illusion; a characteristic biological signal detection unit 72 that analyzes the biological signals and detects a characteristic biological signal indicating a state where the kinesthetic illusion is induced; and a control signal output unit 73 that outputs control signals for controlling body driving means 4 and/or brain simulating means 5, when the characteristic biological signal is detected.