Abstract: The present invention relates to a beef-specific age determination marker containing the p21 protein, to an antibody specifically bound to bovine p21 protein, to a beef-specific age determination kit containing the antibody which is specifically bound to the bovine p21 protein, and to a method which involves detecting the bovine p21 protein through an antigen-antibody binding reaction using the antibody which is specifically bound to the bovine p21 protein serving as a beef-specific age determination marker in the muscle tissue of beef, so as to determine the age of the beef. According to the present invention, the p21 protein is significantly greatly expressed in the muscle tissue of beef, the age of which is lower than 30 months, and is hardly expressed in the muscle tissue of beef, the age of which is greater than 30 months, and thus can be valuably used as a beef-specific age determination marker.

Abstract: A method for preparing hydrophobic gold nanoparticles includes adding 1,2-dichlorobenzene as a solvent to gold precursor and using oleylamine and oleic acid with volume ratio of 7.5:2.5 to 5:5 as surfactants. The size of the prepared gold nanoparticles can be controlled over a broad range and may be utilized in various fields such as bio-imaging, photonic crystallization, sensors, organic catalysts, surface enhanced raman spectrum, electronic devices, etc. Further, a method for colorimetric detection of a strong acid uses hydrophilic nanoparticles that are phase transited from the prepared hydrophobic gold nanoparticles. Up to 5 ppm of low content hydrochloric acid can be detected utilizing phase transited hydrophilic nanoparticles in the colorimetric detection method, and the gold nanoparticles that were used in the detection of strong acid can be reused without loss of activity through neutralization with bases.

Abstract: Disclosed is a gas chromatography chip including: a substrate having an upper substrate and a lower substrate; a gas supply connecting part formed on one plane of one surface of the substrate or on one plane of an opposite surface of the substrate; a gas discharge connecting part formed another plane of the one surface of the substrate or on another plane of the opposite surface of the substrate; a micro channel continuously extending from the gas supply connecting part to the gas discharge connecting part to form a micro channel part and having a circular cross-section; at least two position alignment markers formed on one surface or an opposite surface of the opposite surfaces of the substrate; and a heat transfer part and a temperature control unit for controlling a temperature of the substrate.

Abstract: A method of preparing monoatomic layer black phosphorous by irradiating an ultrasound includes: putting black phosphorus into a solvent and irradiating the ultrasound; recovering a solution from a solution to which the ultrasound is irradiated; and collecting black phosphorus remaining after the solution has been recovered, putting the black phosphorus into a solvent, irradiating the ultrasound, and recovering a solution.

Abstract: Provided is a multiple frequency Radio Frequency (RF) amplifier. The multiple frequency RF amplifier includes a waveform generation circuit configured to generate an RF signal by amplitude and frequency-modulating a reference waveform signal, a drive amplifier circuit configured to drive-amplify the RF signal, and a power amplifier circuit configured to generate a multiple frequency RF voltage signal through a power amplification of the drive-amplified RF signal and output the multiple frequency RF voltage signal to an ion trap for a mass spectrometry.

Abstract: The present invention relates to a more efficient and accurate method for the identification and quantification of comparatively low abundant glycopeptides, compared with general peptides, using mass spectrum obtained by using high resolution mass spectrometer. Therefore, the method of the present invention can be effectively used for the techniques for identification of biotherapeutics and diagnosis of cancer or disease by screening glycopeptide, the disease marker (Biomarker), from various samples.

Abstract: Disclosed is an economic method for concentrating virus and detecting virus, such that virus in a sample solution having low virus concentration can be concentrated with high efficiency within a short time. Particularly, the method comprising the steps of: (A) adding Concanavalin A (Con A) to a sample solution containing a virus, and reacting the added Concanavalin A with the virus in the sample solution to form a virus-Concanavalin A conjugate; and (B) separating the virus-Concanavalin A conjugate from the sample solution.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver, and more specifically relates to a pharmaceutical composition for preventing or treating diabetes or fatty liver containing a CYP4A (cytochrome P450A) inhibitor as an active ingredient. According to the present invention, the CYP4A inhibitor suppresses endoplasmic reticulum stress, reduces the blood insulin concentration and suppresses apoptosis of liver cells, and hence exhibits effects in preventing or treating diabetes or fatty liver.

Abstract: The present invention relates to a new uridine nucleoside-based amphiphilic gadolinium complex and a magnetic resonance imaging (MRI) contrast agent including the gadolinium complex. The MRI contrast agent has high relaxivity, high binding affinity for and stability in human serum albumin, pH response, and high liver specificity.

Abstract: Disclosed is a novel method for detecting interactions of biomolecules. More particularly, the disclosed method includes (a) preparing a cell comprising (i) a first construct comprising a bait, a first labeling material and a translocation module; and (ii) a second construct comprising a prey and a second labeling material; (b) detecting the distribution of the first construct and the second construct in the cell. the present invention provides a method capable of detecting bindings and interactions occurring in a living cell in real time, and a method for screening a material that alters the binding and the interaction. The method of the present invention overcomes the disadvantages including inaccuracy and complexity of existing biomaterial interaction detection techniques. By labeling both constructs to promote accuracy, the present invention provides a novel real-time, antibody-free analysis.

Abstract: A demodulation device according to the present invention includes a spin device configured to output an oscillation signal; a phase control unit configured to assign a predetermined phase locking characteristic to the spin device, thereby causing the oscillation signal to be tuned to a modulation signal that is input to the spin device; and a detector configured to demodulate the oscillation signal that is output by the spin device and tuned to the modulation signal, thereby restoring information carried on the oscillation signal.

Abstract: A lens for electron capture dissociation may include: a first electrode and a second electrode spaced apart from each other and arranged along a first direction; and a third electrode and a fourth electrode spaced apart from each other and arranged along a second direction perpendicular to the first direction. The first electrode and the second electrode may be disposed in a space in which a magnetic field is formed in the first direction and trap electrons. The third electrode and the fourth electrode may be in the form of a flat plate and may apply an electric field to the trapped electrons in the second direction.

Abstract: Provided is a derivatization reaction gas chromatographic chip including: an analysis solution inlet allowing an analysis solution containing an analysis target to be introduced therethrough; a derivative inlet allowing a reaction solution containing a derivative chemically reacting with the analysis target to be introduced therethrough; a guide channel connecting one end of a first micro-channel to each of the analysis solution inlet and the derivative inlet; the first micro-channel in which a fluid flows and the analysis target in the fluid is vaporized; a first outlet connected to the other end of the first micro-channel; a gas phase inlet communicating with the first outlet; a second micro-channel having one end connected to the gas phase inlet and having a stationary phase formed therein; and a second outlet connected to the other end of the second micro-channel.

Abstract: An ion trap mass spectrometer is provided, including: an electron emitter; an ion trap storing ions generated by ionization resulting from an impact with electrons emitted from the electron emitter; a secondary ion filter for blocking out secondary ions generated due to ions selectively released by the ion trap; and a detector detecting ions selectively released from the ion trap, wherein the electron emitter, the ion trap, the secondary ion filter, and the ion detector are arranged on the same axis, so that a pure mass spectrum can be measured by excluding the secondary ions which are causes of background noise signals in the procedure of detection of the ions by the ion trap mass spectrometer.

Abstract: A coaxial drive apparatus for multidirectional control, including: a housing; a stage pivotally installed in the housing, with the object laid on the stage; a rotary shaft connected to the stage and rotated to cause the stage to pivot; a rotation transmitting unit transmitting a rotating force of the rotary shaft to the stage; a sliding pipe coaxially fitted over the rotary shaft so as to be moved along a lengthwise direction of the rotary shaft or to be rotated on a central axis of the rotary shaft; a moving unit moving the object laid on the stage in the lengthwise direction of the rotary shaft according to a movement of the sliding pipe, and moving the object in a transverse direction of the rotary shaft according to a rotation of the sliding pipe; and a controller providing a driving force to the rotary shaft and to the sliding pipe.

Abstract: Provided is a preparing method of an Ag nano-particle for mass-producing Ag nano-particles, the method including: performing a first reaction of a reaction solution containing an Ag precursor and oleylamine at a set first temperature T1; performing a second reaction of the reaction solution at a second temperature T2 set so as to be higher than the first temperature; and obtaining a reactant from the reaction solution, wherein at least one of the first and second reactions is performed in a state in which the reaction solution is not stirred.

Abstract: The present invention relates to a bit for processing the inside diameter of a work material, the bit having on the outer surface of a shank a vibration preventing structure comprising a vibration absorption body made of a silicone material, and a hollow wire rod, thereby absorbing the vibration generated from a machine tool, preventing resonance generated between the work material and a tool, and thus, enabling the implementation of a slickenside from ultra-precision machining.

Abstract: The present invention relates to an ultraviolet diode and an atomic mass analysis ionization source collecting device using an MCP. In the manufacturing of a portable atomic mass analyzer, an object of the present invention is to use an MCP electron multiplier plate, whereby ultraviolet photons emitted from an ultraviolet diode are irradiated on a front surface plate of the MCP electron multiplier plate to induce primary electrons, an amplified electron beam is collected from the electrons, and an electron beam is generated at a low temperature and low power and having a discharge time that is accurately controlled.

Abstract: The present invention provides a neutron generating device for generating a high neutron flux by forming plasma in a high density in the vicinity of a target and by preventing the target surface from being excessively heated. Magnetic field is formed in the vicinity of the target to generate plasma inside a space, in which the magnetic field is formed so as to produce plasma in a high density in the vicinity of the target, thereby allowing a high neutron flux to be emitted from a target. Also, the present invention prevents the target surface from being excessively heated by producing plasma in pulsed mode and by applying target voltage in pulsed mode and secures a continuous process by adjusting a target bias voltage for targets that have depleted the adsorbed elements during the process to allow re-adsorption.

Abstract: A liquid medium plasma discharge generating apparatus includes a main body; a power electrode, provided at one side within the main body, for receiving electric power; a diaphragm member provided within the main body, and consisting of a dielectric defining one or more holes or slits; and a liquid medium charged inside the main body, wherein a ground electrode may be further provided in the main body, opposite the power electrode with the diaphragm member therebetween, whereupon the diaphragm member is arranged contacting the ground electrode.