Abstract: Provided is a compound represented by Formula (1A) below wherein the symbols are as defined in the description: Also disclosed are a composition containing at least one of the compound and a formed article of the compound.

Abstract: The present invention provides an alkaline water electrolysis anode such that even when electric power having a large output fluctuation, such as renewable energy, is used as a power source, the electrolysis performance is unlikely to be deteriorated and excellent catalytic activity is retained stably over a long period of time. The alkaline water electrolysis anode is an alkaline water electrolysis anode 10 provided with an electrically conductive substrate 2 at least a surface of which contains nickel or a nickel base alloy and a catalyst layer 6 disposed on the surface of the electrically conductive substrate 2, the catalyst layer 6 containing a nickel-containing metal oxide having a spinel structure, wherein the nickel-containing metal oxide contains nickel (Ni) and manganese (Mn), and has an atom ratio of Li/Ni/Mn/O of (0.0 to 0.8)/(0.4 to 0.6)/(1.0 to 1.8)/4.0.

Abstract: Provided is a carbon dioxide recovery system that separates CO2 from a CO2-containing gas containing CO2 by an electrochemical reaction, and comprises an electrochemical cell comprising a working electrode containing a CO2 adsorbent, and a counter electrode. Application of a voltage between the working electrode and the counter electrode causes electrons to be supplied from the counter electrode to the working electrode, and enables the CO2 adsorbent to bind to CO2 as electrons are supplied. The CO2 adsorbent is a crystalline porous body, and has a molecular structure in which a functional group that exchanges electrons and binds to CO2 is regularly arranged.

Abstract: A two-dimensional photonic crystal laser includes: electrodes; an active layer; and a two-dimensional photonic crystal layer in which modified refractive index regions are disposed to be shifted by different shift amounts from respective lattice points or/and are disposed at the respective lattice points with different areas, the shift amount or/and the area is/are modified with a composite modulation period and expressed by a modulation phase ?(r?) expressed using a vector r? indicating a position of each lattice point of the two-dimensional lattice, a vector kn? indicating a combination of an inclination angle and an azimuthal angle of each of n laser beams mutually differing in the inclination angle and/or the azimuthal angle, and an amplitude An and a phase exp(i?n) determined for each n and the amplitude An and/or the phase exp(i?n) for each value of n differ(s) from each other in at least two different values of n.

Abstract: A brain measurement apparatus includes: a magnetoencephalograph including optically pumped magnetometers, magnetic sensors for measuring geomagnetic field at positions of the optically pumped magnetometers, magnetic sensors for measuring a fluctuating magnetic field at the positions of the optically pumped magnetometers, nulling coils for cancelling the geomagnetic field, and an active shield coil for cancelling the fluctuating magnetic field; an MRI apparatus including nulling coils for applying a static magnetic field and a gradient magnetic field, a transmission coil, and a receive coil; and a control device that, when measuring a brain's magnetic field, controls currents supplied to the nulling coils and the active shield coil based on measured values of the magnetic sensors and, when measuring an MR image, controls the static magnetic field and the gradient magnetic field by controlling currents supplied to the nulling coils and generates an MR image from an output of the receive coil.

Abstract: Provided is a method for inducing pluripotent stem cells to differentiate into somatic cells in a culture medium containing a heparin binding growth factor, the method comprising bringing cells into contact with a conjugate of a laminin E8 fragment and a growth factor binding domain-containing fragment of a heparan sulfate proteoglycan. According to the present invention, pluripotent stem cells can be induced to differentiate into any desired somatic cells in a highly efficient manner.

Abstract: As a technique for proliferating neural crest cells without reducing differentiation capacity, provided is a method for producing neural crest cells, comprising the steps of: (1) obtaining neural crest cells; and (2) suspension-culturing the neural crest cells in a medium comprising a GSK3? inhibitor and a basic fibroblast growth factor (bFGF), wherein the medium comprises the GSK3? inhibitor with a concentration that exhibits an effect equivalent to that exhibited by CHIR99021 with a concentration of higher than 1 ?M and lower than 5 ?M.

Abstract: In a method for producing hydrogen and carboxylic acid, a primary alcohol of 1 to 7 carbon atoms and water are reacted by being continuously introduced into a flow reactor packed with a solid catalyst consisting of an alloy of ruthenium and tin on a support and passed through the reactor under temperature and pressure conditions at which the water assumes a gaseous state. This method enables hydrogen and carboxylic acid to be produced in a high yield or at a high purity from a primary alcohol and water in a short time and by simple operations.

Abstract: A method for producing a three-dimensional tissue construct comprising mature adipocytes, comprising incubating cells comprising at least fat-derived stein cells in the presence of one or more fatty acids selected from the group consisting of erucic acid, elaidic acid, oleic acid, palmitoleic acid, myristoleic acid, phytanic acid, and pristanic acid.

Abstract: A demand prediction device derives a first exponential function indicating the time-series transition of the number of bookings until a service provision time point for a first customer group based on the transition of the number of bookings until a time point t1 for the first group. A demand prediction device derives a second exponential function indicating the time-series transition of the number of bookings until a service provision time point for a second customer group based on the transition of the number of bookings until a time point t2 for the second customer group different from the first group. The demand prediction device generates information supporting a service providing entity based on the time-series transition of the number of bookings until an analysis target time point for the first customer group indicated by the first exponential function and that for the second customer group by the second exponential function.

Abstract: A cell population comprising Corin- and/or Lrtm1-positive cells was produced by the following steps (1) and (2), from which Corin positive and/or Lrtm1 positive cells are collected using a substance that binds to Corin and/or a substance that binds to Lrtm1, and dopaminergie neuron progenitor cells are produced by performing suspension culture of the Corin positive and/or Lrtm1 positive cells in a culture solution containing one or more nutritional factors: (1) a step of performing adhesion culture of pluripotent stem cells in a medium for maintaining undifferentiated state containing a Sonic hedgehog (SHH) signal stimulant, and an undifferentiated state-maintaining factor in the absence of feeder cells but in the presence of an extracellular matrix, and (2) a step of culturing the cell population obtained in the step (1) in a culture solution containing one or more differentiation-inducing factors.

Abstract: A two-dimensional photonic-crystal surface-emitting laser includes: a two-dimensional photonic-crystal layer; an active layer provided on one surface side of the two-dimensional photonic-crystal layer; and a reflection layer provided on the other surface side of the two-dimensional photonic-crystal layer or on a side opposite to the two-dimensional photonic-crystal layer so as to be spaced apart from the two-dimensional photonic-crystal layer, wherein a distance d between surfaces of the two-dimensional photonic-crystal layer and the reflection layer facing each other is set such that a radiation coefficient difference ??v=(?v1??v0), which is a value obtained by subtracting a radiation coefficient ?v0 of a fundamental mode having the smallest loss from a radiation coefficient ?v1 of a first higher order mode having the second smallest loss among the light amplified in the two-dimensional photonic-crystal layer, is 1 cm?1 or more.

Abstract: Healthy functional platelets are mass produced. A method for producing platelets, comprising: (1) a culture step of culturing megakaryocytes in a platelet producing medium in the presence of mechanical stress and platelet production promoting factors including MIF, NRDc, IGFBP2, TSP-1, PAI-1, and CCL5, and (2) a harvest step of harvesting the platelets obtained by the culture step; wherein the culture step comprises: (a) a step of promoting a release of the platelet production promoting factors from megakaryocytes by mechanical stress; and/or (b) a step of externally adding platelet production promoting factors including MIF, NRDc, and IGFBP2.

Abstract: Provided is a novel device (implantation device) containing a gelatin. The implantation device is made of a bioabsorbable non-woven fabric containing a gelatin.

Abstract: Provided is an orally administrable vaccine against a coronavirus infectious disease. A transformed Bifidobacterium designed to display a part or a whole of a constituent protein of a coronavirus on a surface of the Bifidobacterium enables the provision of the orally administrable vaccine against a coronavirus infectious disease. The transformed Bifidobacterium designed to display a part or a whole of a constituent protein of a coronavirus on a surface of the Bifidobacterium can induce humoral immunity and cellular immunity through oral administration to suppress an increase in severity of pneumonia or the like even after viral infection.

Abstract: An actuator unit of the present invention includes upper and lower frames respectively connectable to a thigh frame and a lower leg frame, an actuator-side rotational connecting part connecting both frames in a rotatable manner around a pivot axis, a driver producing driving force for rotating the lower frame around the pivot axis, upper and lower connecting bodies respectively connecting the upper frame to the thigh frame and the lower frame to the lower leg frame, and an intermediate connecting body connecting the vicinity of the actuator-side rotational connecting part to the vicinity of a brace-side rotational connecting part, the intermediate connecting body having a ball stud and an accommodation depression respectively provided on one and the other of the knee-ankle-foot orthosis and the actuator unit.

Abstract: Provided are vitamin D3 derivatives of formula (I), pharmaceutical compositions thereof, and pharmaceutical or medical uses thereof for treating metabolic disease, a liver disease, obesity, diabetes, cardiovascular disease, or cancer in a patient in need thereof.

Abstract: A magnetic resonance member 1 includes a crystal structure and is capable of electron spin quantum operations with microwaves of different frequencies corresponding to arrangement orientations of a vacancy and an impurity in a crystal lattice. A magnetic field transmission unit 4 senses a measurement target magnetic field at plural measurement positions different from each other, and applies application magnetic fields corresponding to the measurement target magnetic field sensed at the plural measurement positions to the magnetic resonance member 1 along respective different directions corresponding to the aforementioned arrangement orientations. A measurement control unit 21 controls a high frequency power supply 12, and determines detection values detected by a detecting device (an irradiating device 5 and a light receiving device 6) of the physical phenomena corresponding to the plural measurement positions.

Abstract: The present invention provides a stereocontrol catalyst for use in radical polymerization that is applicable to polymerization of a broad range of monomers and that enables polymerization with control of both molecular weight (molecular weight distribution) and stereoselectivity, a method for producing a polymer using the stereocontrol catalyst for use in radical polymerization, and an acrylic polymer. Provided is a stereocontrol catalyst for use in radical polymerization, containing: a rare-earth metal salt compound; and a hydroxy group-containing compound.

Abstract: [PROBLEM] The problem to be solved by the invention is to provide a novel pharmaceutical use of a JAK inhibitor. [SOLUTION MEANS] A therapeutic or preventive agent for a skin disease selected from the group consisting of senile xerosis, asteatosis, eczema and contact dermatitis, containing a JAK inhibitor as an active ingredient. [EFFECT] The followings are found: a JAK inhibitor increases the expression amounts of filaggrin, loricrin, involucrin and ?-defensin 3 as skin barrier function-related proteins; a JAK inhibitor significantly increases NMF production in a Tape Stripping-treated mouse; and a JAK inhibitor significantly accelerates a reduction in TEWL in a dry skin mouse model, namely improves the skin barrier function. The JAK inhibitor can be used as an active ingredient of a therapeutic or preventive agent for skin diseases such as senile xerosis, asteatosis, eczema, contact dermatitis, ichthyosis vulgaris, Netherton syndrome, type B peeling skin syndrome, etc.