Patents Assigned to Kyoto University
  • Patent number: 11189846
    Abstract: An electrically-conductive member having sufficient corrosion resistivity even when the electrically-conductive member is exposed to high potential environment and a method of manufacturing the electrically-conductive member are offered. An electrically-conductive member is obtained by a mist CVD method, by forming a metal oxide film on a base member of a separator, and the electrically-conductive member has an active potential range and a passive potential range in an anode polarization curve that is measured in a sulfuric acid aqueous solution having a sulfuric acid concentration that is 5.0×10?4 mol/dm3 at pH3 and having a temperature of 25° C., an anode current density that is 1×10?7 A/cm2 or less in the passive potential range, and the passive potential range reaching to an electric potential that is 1V.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: November 30, 2021
    Assignees: FLOSFIA INC., EYETEC CO., LTD., KYOTO UNIVERSITY
    Inventors: Shizuo Fujita, Masafumi Ono, Takayuki Uchida, Kentaro Kaneko, Takashi Tanaka, Toshimi Hitora, Shingo Yagyu
  • Patent number: 11181439
    Abstract: According to one embodiment, a structure evaluation system according to an embodiment includes a plurality of sensors, a position locator, and an evaluator. The plurality of sensors detect elastic waves. The position locator locates positions of elastic wave sources by using the elastic waves among the plurality of elastic waves respectively detected by the plurality of sensors having an amplitude exceeding a threshold value determined according to positions of the sources of the plurality of elastic waves and the positions of the plurality of disposed sensors. The evaluator evaluates a deteriorated state of the structure on the basis of results of the position locating of the elastic wave sources which is performed by the position locator.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: November 23, 2021
    Assignees: Kabushiki Kaisha Toshiba, Kyoto University
    Inventors: Tomoki Shiotani, Katsufumi Hashimoto, Hidefumi Takamine, Kazuo Watabe
  • Patent number: 11179471
    Abstract: Provided is a peptide represented by the following formula (I): R1-IWLTALX5FLGX6X1AAX7X2X3AX8QX4LSX9L-R2?(I) wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, R1, and R2 are as defined in the specification.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: November 23, 2021
    Assignee: KYOTO UNIVERSITY
    Inventors: Shiroh Futaki, Kentarou Sakamoto, Misao Akishiba
  • Patent number: 11179450
    Abstract: A long-chain peptide antigen includes a plurality of epitopes. An interepitope sequence located between two of the plurality of epitopes contains four to ten consecutive tyrosines. The long-chain peptide antigen may be administered to a patient together with a hydrophobized polysaccharide, such as cholesterol-modified pullulan, and/or an adjuvant, such as CpG oligo DNA.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: November 23, 2021
    Assignees: MIE UNIVERSITY, KYOTO UNIVERSITY
    Inventors: Hiroshi Shiku, Naozumi Harada, Daisuke Muraoka, Kazunari Akiyoshi
  • Patent number: 11179411
    Abstract: An object of the present invention is to provide ASO that can effectively suppress a formation of RNA foci spontaneously occurring in neurons having SCA36 mutation, without inducing the cleavage of NOP56 pre-mRNA. The present invention provides an oligonucleotide comprising a nucleotide sequence in which one or more nucleotide sequences represented by SEQ ID NO: 2 are consecutively connected and is complementary to pre-mRNA of NOP56 gene, wherein a structure formed by the hybridization of the oligonucleotide to the pre-mRNA is resistant to RNaseH.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: November 23, 2021
    Assignee: KYOTO UNIVERSITY
    Inventors: Haruhisa Inoue, Keiko Imamura, Kosuke Matsuzono
  • Publication number: 20210353686
    Abstract: The purpose of the present invention is to provide a novel method for making it possible to efficiently induce/produce endocrine cells from pluripotent stem cells. Insulin-producing cells including cells that are insulin-positive and NKX6.1-positive cells in a ratio of at least 30% and cells that are insulin-positive and NKX6.1-negative in a ratio of more than 15%.
    Type: Application
    Filed: September 18, 2019
    Publication date: November 18, 2021
    Applicants: Takeda Pharmaceutical Company Limited, Kyoto University
    Inventors: Ryo ITO, Noriko YAMAZOE, Hideyuki HIYOSHI, Taisuke MOCHIDA, Hikaru UENO, Kensuke SAKUMA, Junji YAMAURA, Hirokazu MATSUMOTO, Taro TOYODA, Shuhei KONAGAYA
  • Patent number: 11178493
    Abstract: An electroacoustic transducer includes: a diaphragm; a magnetic circuit having a magnetic gap; a frame that holds the diaphragm and the magnetic circuit; a voice coil having one end portion positioned within the magnetic gap and the other end portion coupled to the diaphragm; and a low friction material that is disposed in a sliding portion formed by the voice coil and the magnetic circuit, and includes polymer compounds swollen with liquid.
    Type: Grant
    Filed: March 26, 2020
    Date of Patent: November 16, 2021
    Assignees: Panasonic Corporation, KYOTO UNIVERSITY, National University Corporation YOKOHAMA National University
    Inventors: Hidetoshi Hiraoka, Yoshinobu Tsujii, Keita Sakakibara, Ken Nakano
  • Publication number: 20210350261
    Abstract: A learning-type real space information generation system uses sensor data that can be efficiently uploaded from an information terminal device to a server, and which is capable of generating highly accurate real space information. A plurality of information terminal devices and a server are connected via in a communicable state via a network. The control unit of each information terminal device controls a transmission unit, based on the importance of elements configuring real space information, the importance being determined by an importance determination unit of the server such that sensor data corresponding to an element configuring the real space information and having high importance is preferentially transmitted. The generation unit of the server uses a feature model to generate real space information, based on elements configuring real space information and having high importance extracted by an extraction unit from the most recent sensor data received by a reception unit.
    Type: Application
    Filed: October 2, 2019
    Publication date: November 11, 2021
    Applicant: KYOTO UNIVERSITY
    Inventor: Ryoichi SHINKUMA
  • Patent number: 11168170
    Abstract: A clearance narrowing material containing a brush-shaped polymer chain aggregate formed of multiple polymer chains immobilized on a substrate. The invention provides a clearance narrowing material which can effectively prevent fluid leakage through a clearance and which does not disturb relative movement of members to form a clearance, and can realize an article in which fluid leakage through a clearance can be effectively prevented and the members to form a clearance can move smoothly.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: November 9, 2021
    Assignees: KYOTO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY, NATIONAL INSTITUTE OF TECHNOLOGY
    Inventors: Chiharu Tadokoro, Takuo Nagamine, Yoshinobu Tsujii, Keita Sakakibara, Ken Nakano, Hitoshi Hattori, Shinya Sasaki, Takaya Sato
  • Publication number: 20210340478
    Abstract: A cell culture chip includes a plate having a first surface, a first opening formed inside the plate and having one end exposed on the first surface, a second opening formed inside the plate and at a location different from the first opening and having one end exposed on the first surface, a hollow connecting section communicating with the other end of the first opening and the other end of the second opening, and a water repellent section with water repellent treatment being provided at least in the vicinity of the first opening or the second opening on the first surface of the plate.
    Type: Application
    Filed: November 1, 2019
    Publication date: November 4, 2021
    Applicants: Ushio Denki Kabushiki Kaisha, Kyoto University
    Inventors: Makoto Yamanaka, Kenichiro Kamei
  • Publication number: 20210322531
    Abstract: A mucosal vaccine composition for preventing bovine mastitis, comprising: an antigen derived from Staphylococcus aureus; and a nanogel comprising a polysaccharide having a cationic functional group and a hydrophobic functional group in side chains. By administering the composition to cattle, it is possible to enhance the titer of an antibody against Staphylococcus aureus immediately after the contact with the bacteria in the udder, and prevent the bovine mastitis.
    Type: Application
    Filed: August 2, 2019
    Publication date: October 21, 2021
    Applicants: National Agriculture and Food Research Organization, Kyoto University, TOHOKU UNIVERSITY
    Inventors: Tomohito HAYASHI, Yoshio KIKU, Yuya NAGASAWA, Kazunari AKIYOSHI, Shin-ichi SAWADA, Hisashi ASO, Tomonori NOCHI
  • Publication number: 20210328406
    Abstract: A surface emitting laser element formed of a group III nitride semiconductor, comprising: a first clad layer of a first conductivity type; a first guide layer of the first conductivity type having a photonic crystal layer formed on the first clad layer including voids disposed having two-dimensional periodicity in a surface parallel to the layer and a first embedding layer formed on the photonic crystal layer; a second embedding layer formed on the first embedding layer by crystal growth; an active layer formed on the second embedding layer; a second guide layer formed on the active layer; and a second clad layer of a second conductivity type formed on the second guide layer, the second conductivity type being a conductivity type opposite to the first conductivity type. The first embedding layer has a surface including pits disposed at surface positions corresponding to the voids.
    Type: Application
    Filed: August 29, 2019
    Publication date: October 21, 2021
    Applicants: KYOTO UNIVERSITY, STANLEY ELECTRIC CO., LTD.
    Inventors: Susumu NODA, Yoshinori TANAKA, Menaka DE ZOYSA, Kenji ISHIZAKI, Tomoaki KOIZUMI, Kei EMOTO
  • Publication number: 20210322582
    Abstract: The present invention provides a radiolabeled compound represented by the following formula (1), which is a radioactive imidazothiadiazole derivative compound having an affinity for CA-IX, or a salt thereof. wherein n is an integer of 1 to 4, and L represents a radionuclide or a mono- to tetravalent group containing a radionuclide.
    Type: Application
    Filed: August 30, 2019
    Publication date: October 21, 2021
    Applicants: Nihon Medi-Physics Co., Ltd., Kyoto University
    Inventors: Masato KIRIU, Norihito NAKATA, Tsutomu ABE, Masahiro ONO
  • Patent number: 11152208
    Abstract: A semiconductor film containing silicon that is evenly doped in the semiconductor film with an enhanced semiconductor property and a method of the semiconductor film using a dopant material containing a complex compound that contains at least silicon and a halogen. The complex compound further contains a hydrocarbon group that is optionally substituted or heterocyclic group that is optionally substituted. A semiconductor film containing Si doped into the semiconductor film as a dopant to a depth that is at least 0.3 ?m or deeper from a surface of the semiconductor film is obtained by forming the semiconductor film in that the dopant material is doped, the semiconductor film is 100 ?m or less in film thickness with carrier density that is 1×1020/cm3 or less and electron mobility that is 1 cm2/Vs or more.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: October 19, 2021
    Assignees: FLOSFIA INC., KYOTO UNIVERSITY
    Inventors: Shizuo Fujita, Takayuki Uchida, Kentaro Kaneko, Masaya Oda, Toshimi Hitora
  • Publication number: 20210318493
    Abstract: A multiplexing optical system includes a light source, a lens and a lens array. The light source includes a plurality of light emitting elements of surface emitting lasers. The lens is configured to change and condense optical paths of laser light beams emitted from the light emitting elements. The lens array includes a plurality of lens regions arrayed so as to correspond to respective optical paths of the laser light beams changed by the lens, and is configured to condense the laser light beams by the lens regions to form a multiplexed beam.
    Type: Application
    Filed: September 13, 2019
    Publication date: October 14, 2021
    Applicants: Mitsubishi Electric Corporation, Kyoto University
    Inventors: Yoko INOUE, Masato KAWASAKI, Tatsuya YAMAMOTO, Kazuki KUBA, Susumu NODA
  • Patent number: 11144789
    Abstract: Provided is a model parameter learning device and the like capable of learning model parameters such that the influence of a noise in input data can be suppressed. A model parameter learning device (1) alternately carries out first learning processing for learning model parameters W1, b1, W2 and b2 such that an error between data Xout and data Xorg is minimized, and second learning processing for learning model parameters W1, b1, Wm, bm, Wq and bq such that a loss function LAE is minimized.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: October 12, 2021
    Assignees: HONDA MOTOR CO., LTD., KYOTO UNIVERSITY
    Inventors: Kosuke Nakanishi, Yuji Yasui, Wataru Sasaki, Shin Ishii
  • Patent number: 11141529
    Abstract: An infusion set (1) includes: a first flow path (10a) having a first connector (11a) and a downstream connector (19); a first open/close valve (12a), a first liquid surface sensor (13a), a second liquid surface sensor (13b), a drip chamber (14), and a variable valve (17) that are provided in this order on the first flow path from the first connector side toward the downstream connector side; a droplet sensor (15) with which the drip chamber is provided; a second flow path (10b) having a second connector (11b); and a second open/close valve (12b) provided on the second flow path. The second flow path is in communication with a portion of the first flow path between the first liquid surface sensor and the second liquid surface sensor. The controller is configured to control the first and second open/close valves and the variable valves based on signals from the first and second liquid surface sensors and the droplet sensor.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: October 12, 2021
    Assignees: JMS CO., LTD., Kyoto University
    Inventors: Tadashi Okiyama, Hirofumi Nakagawa, Masashi Kanai, Yoko Hamabe
  • Patent number: 11142483
    Abstract: The present invention provides a silicon carbide fiber reinforced silicon carbide composite material, which is a composite material of SiC fibers and SiC ceramics with improved toughness and can be produced with high yield by relatively simple steps without complex steps such as a step of oxidation-resistant coating or an advanced interface control step. The silicon carbide composite material comprises a multiphase matrix and silicon carbide fibers disposed in the matrix, the matrix containing a silicon carbide phase and a phase that includes a substance of low reactivity with respect to silicon carbide. It can be obtained by steps suitable for mass production and ensures greatly improved fracture toughness while maintaining the excellent properties of SiC ceramics.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: October 12, 2021
    Assignee: Kyoto University
    Inventors: Tatsuya Hinoki, Kazuya Shimoda
  • Publication number: 20210311019
    Abstract: The present invention relates to a method for screening an inhibitor of ATP11C or CDC50A, comprising determining (a) exposure of phosphatidylserine on cell surface, (b) engulfment of cells by macrophages, or (c) cleavage of ATP11C by caspase. The present invention also relates to a method for inducing engulfment of cells by macrophages, comprising inhibiting ATP11C or CDC50A.
    Type: Application
    Filed: June 17, 2021
    Publication date: October 7, 2021
    Applicant: KYOTO UNIVERSITY
    Inventors: Shigekazu NAGATA, Katsumori SEGAWA
  • Patent number: 11136547
    Abstract: Provided is a method for inducing mesoderm, comprising a step of bringing pluripotent stem cells into contact with bone morphogenetic protein 4 (BMP4) or CHIR for at least 3 days.
    Type: Grant
    Filed: March 22, 2017
    Date of Patent: October 5, 2021
    Assignees: Kyoto University, Megakaryon Corporation
    Inventors: Koji Eto, Hiroshi Endo, Yukitaka Ito, Junichi Fukunaga