Patents Assigned to Kyoto University
  • Publication number: 20200368267
    Abstract: The present invention provides a prophylactic and/or therapeutic agent for ALS containing a Src/c-Abl pathway inhibitor.
    Type: Application
    Filed: November 22, 2018
    Publication date: November 26, 2020
    Applicant: KYOTO UNIVERSITY
    Inventors: Haruhisa INOUE, Keiko IMAMURA
  • Publication number: 20200362303
    Abstract: The present invention provides a method for expanding PGC/PGCLC, including culturing PGC/PGCLC in the presence of a phosphodiesterase 4 (PDE4) inhibitor and/or cyclosporine A, further in the presence of forskolin, and a method for inducing oocytes from PGC/PGCLC, including culturing PGC/PGCLC in the presence of bone forming protein (BMP) and retinoic acid (RA).
    Type: Application
    Filed: November 30, 2018
    Publication date: November 19, 2020
    Applicant: KYOTO UNIVERSITY
    Inventors: Mitinori SAITOU, Hiroshi OHTA, Hidetaka MIYAUHI
  • Patent number: 10816536
    Abstract: A bioparticle observation apparatus includes a dielectrophoresis electrode that outputs a first signal causing a dielectrophoresis force to act on a bioparticle, a sensor electrode that detects an impedance difference between the bioparticle and the liquid, and a control circuit that controls the first signal so that the detected impedance difference is fixed.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: October 27, 2020
    Assignees: SHARP KABUSHIKI KAISHA, KYOTO UNIVERSITY
    Inventors: Takeshi Mitsunaka, Yuichi Ogawa
  • Patent number: 10808065
    Abstract: Provided are a method for producing a multibranched polymer that can produce a multibranched polymer having a narrow molecular weight distribution in a one-pot procedure and the multibranched polymer. A method for producing a multibranched polymer includes the step of polymerizing a first vinyl monomer having a polymerization-initiating group in an ?-position of a vinyl bond and a second vinyl monomer free of polymerization-initiating group in an ?-position of a vinyl bond by a living radical polymerization.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: October 20, 2020
    Assignees: KYOTO UNIVERSITY, OTSUKA CHEMICAL CO., LTD.
    Inventors: Shigeru Yamago, Minoru Yamamoto
  • Publication number: 20200315899
    Abstract: The present invention provides an actuator-equipped knee ankle foot orthosis in which a control device calculates a thigh phase angle based on an angle-related signal detected by a thigh orientation detecting means at one sampling point, applies the thigh phase angle at that sampling point to an assisting force control data, which is stored in the control device in advance and indicates the relationship between the thigh phase angle and a size of the assisting force to be imparted to a lower leg-side brace, to obtain the size of the assisting force to be imparted to the lower leg-side brace at that sampling point, and executes operational control for an actuator unit such that the assisting force having the size is output.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 8, 2020
    Applicant: Kyoto University
    Inventors: Rei TAKAHASHI, Yuichi Sawada, Yoshiyukl Higashi, Tadao Tsuboyama, Noriaki Ichihashi, Koji Ohata, Toshikazu Kawagughi
  • Patent number: 10797393
    Abstract: An IC tag reading device is provided that has increased directivity and is capable of determining an accurate position of an IC tag inserted into and placed in a human body even when the operation range of the antenna of the reading device is limited, such as in thoracoscopy, without causing reduction in detectable distance. A reading device antenna for reading an IC tag that has been inserted into a human body and placed at a certain position in order to locate a lesion includes a coil portion having a coil with a predetermined number of turns in a circumferential direction, and a shield portion that covers at least an approximately half of the coil portion in the circumferential direction and causes a bias in a magnetic flux generated from the coil.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: October 6, 2020
    Assignees: KYOTO UNIVERSITY, HOGY MEDICAL CO., LTD., IDEC AUTO-ID SOLUTIONS CORPORATION
    Inventors: Toshihiko Sato, Yojiro Yutaka, Koichi Matsushita, Jiro Kato, Kaoru Nayuki
  • Patent number: 10794990
    Abstract: A structure evaluation apparatus has an acquisitor and an evaluator. The acquisitor acquires a distribution that represents a distribution of strength of a reflected wave obtained by an electromagnetic radar scan to a reinforced concrete which comprises concrete and a material other than concrete. The evaluator calculates similarity, with reference to a reference region including the material in the distribution, of other regions including the material than the reference region in the distribution.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: October 6, 2020
    Assignees: Kabushiki Kaisha Toshiba, Kyoto University
    Inventors: Hidefumi Takamine, Kazuo Watabe, Tomoki Shiotani
  • Patent number: 10793819
    Abstract: A liquid injection method for injecting a liquid into a culture vessel includes tilting the culture vessel around a horizontal axis at a tilt angle (X°) of greater than 0° and 50° or less, wherein adherent cells are adhered to the culture vessel; and injecting the liquid into the culture vessel at a predetermined linear velocity (Y mm/s) via a wall surface of the culture vessel tilted at the tilt angle (X°), wherein the tilt angle (X) and the linear velocity (Y) satisfy the following (formula 1): Y?5.075X+123 (formula 1).
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: October 6, 2020
    Assignees: KANEKA CORPORATION, KYOTO UNIVERSITY
    Inventors: Tomohisa Kato, Kazuya Hamada, Haruhisa Inoue, Takayuki Kondo
  • Patent number: 10785061
    Abstract: A propagation channel estimation method is provided. In-phase and quadrature components of a propagation channel estimation value in each pilot subcarrier are separated into amplitude and phase components. A propagation channel of a data subcarrier portion existing between pilot subcarriers is estimated by phase/amplitude separation linear interpolating in each separated amplitude and phase component. A reference parameter is produced by linear interpolating a portion between pilot subcarriers on a complex plane. When quadrants on the complex plane of the interpolated phase component estimation value and the reference parameter are different, a phase connecting process to cancel a discontinuity of the phases is executed to the phase component estimation value interpolated by the phase/amplitude separation linear interpolation.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: September 22, 2020
    Assignee: KYOTO UNIVERSITY
    Inventors: Hiroshi Harada, Keiichi Mizutani, Kiminobu Makino
  • Publication number: 20200289605
    Abstract: An object of the present invention is to provide a composition for preventing or improving fat deposition on the liver in spite of the alcohol intake history of a level that a liver disease is not caused. The inventors found that glutathione has an effect of preventing or improving fat deposition on the liver, which is not caused by alcohol, and completed the present invention. Among nonalcoholic fat diseases, the present invention is particularly effective in an early stage of the treatment or in a case where treatment for another disease is not performed.
    Type: Application
    Filed: June 1, 2020
    Publication date: September 17, 2020
    Applicants: KOHJIN LIFE SCIENCES CO., LTD., PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, SAGA UNIVERSITY
    Inventors: Takaomi KESSOKU, Atsushi NAKAJIMA, Yoshio SUMIDA, Yuichiro EGUCHI, Susumu SAITO, Yusuke SAUCHI
  • Patent number: 10774098
    Abstract: Provided is a method for separating the four optical isomers of Nahlsgen.
    Type: Grant
    Filed: September 12, 2017
    Date of Patent: September 15, 2020
    Assignees: KYOTO UNIVERSITY, NAHLS CORPORATION CO., LTD.
    Inventors: Jun Hiratake, Bunta Watanabe, Ryuzo Yoshioka, Hideaki Ishida
  • Patent number: 10777972
    Abstract: A thermal radiation light source includes a laminated body including m quantum layers laminated where m is an integer of 2 or more, including an n-layer and a p-layer sandwiching the quantum layers from both sides in the laminating direction, the n-layer made of an n-type semiconductor and the p-layer made of a p-type semiconductor; a voltage applying unit for the m quantum layers is directly or indirectly connected to the n-layer and p-layer sandwiching each layer applying a voltage for moving to the n-layers or p-layers a charge; a voltage switching unit switches ON/OFF of application of the voltage to the m quantum layers; and a photonic crystal portion disposed in the laminated body or adjacent to the laminated body, so that lights of m wavelengths resonate, the lights of the m wavelengths generated in the m quantum layers corresponding to transition energy between subbands in the quantum layer.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: September 15, 2020
    Assignee: KYOTO UNIVERSITY
    Inventors: Susumu Noda, Takuya Inoue, Anqi Ji, Takashi Asano
  • Publication number: 20200284793
    Abstract: New use of ADAMTS13 in the clinical filed is provided. The use of ADAMTS13 as a biomarker for monitoring the onset of liver damage, hepatic ischemia/reperfusion injury or the liver function after liver transplantation: a method of testing liver damage, a method of testing hepatic ischemia/reperfusion injury, or a method of testing the liver function after liver transplantation, each of the methods comprising measuring or monitoring the ADAMTS13 activity in a sample from a mammal; an agent for treating diseases selected from the group consisting of liver damage, hepatic ischemia/reperfusion injury and hepatic dysfunction after liver transplantation, which comprises ADAMTS13 or a mutant of ADAMTS13 as an effective ingredient.
    Type: Application
    Filed: January 6, 2017
    Publication date: September 10, 2020
    Applicants: Kyoto University, KM BIOLOGICS CO., LTD.
    Inventors: Koichiro HATA, Shinji UEMOTO, Hirofumi HIRAO, Toyonari KUBOTA
  • Publication number: 20200283804
    Abstract: The present disclosure provides a novel aldehyde synthase gene having activity of synthesizing a medium-chain aldehyde. Such gene encodes a protein comprising the amino acid sequence as shown in SEQ ID NO: 2.
    Type: Application
    Filed: March 3, 2020
    Publication date: September 10, 2020
    Applicants: Toyota Jidosha Kabushiki Kaisha, Kyoto University
    Inventors: Masayoshi Muramatsu, Shusei Obata, Masakazu Ito, Jun Ogawa, Shigenobu Kishino
  • Patent number: 10770753
    Abstract: The object of the present invention is to provide an electrolyte for a fluoride ion battery with high activity for fluoridating an active material. The present invention solves the problem by providing an electrolyte for a fluoride ion battery comprising a fluoride complex salt as at least one of LiPF6 and LiBF4, and an organic solvent; and B/A is 0.125 or more in the case where a substance amount of the organic solvent is regarded as A (mol) and a substance amount of the fluoride complex salt is regarded as B (mol).
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: September 8, 2020
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, KYOTO UNIVERSITY
    Inventors: Hirofumi Nakamoto, Zempachi Ogumi, Takeshi Abe
  • Publication number: 20200267027
    Abstract: A propagation channel estimation method is provided. In-phase and quadrature components of a propagation channel estimation value in each pilot subcarrier are separated into amplitude and phase components. A propagation channel of a data subcarrier portion existing between pilot subcarriers is estimated by phase/amplitude separation linear interpolating in each separated amplitude and phase component. A reference parameter is produced by linear interpolating a portion between pilot subcarriers on a complex plane. When quadrants on the complex plane of the interpolated phase component estimation value and the reference parameter are different, a phase connecting process to cancel a discontinuity of the phases is executed to the phase component estimation value interpolated by the phase/amplitude separation linear interpolation.
    Type: Application
    Filed: December 15, 2016
    Publication date: August 20, 2020
    Applicant: KYOTO UNIVERSITY
    Inventors: Hiroshi HARADA, Keiichi MIZUTANI, Kiminobu MAKINO
  • Patent number: 10750579
    Abstract: An induction heating device includes: a rotor having a rotation shaft; a heating part disposed to be opposed to the rotor at a distance; a magnetic flux generating part provided at the rotor to generate magnetic flux for the heating part; a magnetic flux guide part provided on an opposed surface side of the heating part that is opposed to the magnetic flux generating part to guide the magnetic flux from the magnetic flux generating part to the heating part; and a flow passage provided in the heating part to allow a heating medium to circulate. The magnetic flux guide part includes magnetic substance parts. The magnetic flux guide part has a structure in which the magnetic substance parts and the insulator parts extend along a direction from the magnetic flux generating part to the heating part and are alternately layered along a circumferential direction of the heating part.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: August 18, 2020
    Assignees: Sumitomo Electric Industries, Ltd., Kyoto University
    Inventors: Toru Okazaki, Tetsuji Matsuo
  • Publication number: 20200253889
    Abstract: The invention pertains to a compound of formula (I), one of its pharmaceutically acceptable salts, or a composition comprising thereof, for use in the prevention or treatment of glucose intolerance related conditions, insulin deficit related conditions, nonalcoholic fatty liver disease and/or obesity.
    Type: Application
    Filed: October 4, 2018
    Publication date: August 13, 2020
    Applicants: SORBONNE UNIVERSITÉ, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS, KYOTO UNIVERSITY
    Inventors: Dominique Gauguier, Fumihiko Matsuda, François Brial
  • Publication number: 20200254105
    Abstract: Provided is a curcumin pharmaceutical preparation that is highly water soluble, can maintain the concentration of free curcumin in the blood sufficiently high by being administered parenterally, can effectively obtain a pharmacological action of curcumin, and is highly safe. A pharmaceutical composition for parenteral administration, including a water-soluble substance conjugate of curcumin as an active component.
    Type: Application
    Filed: April 27, 2020
    Publication date: August 13, 2020
    Applicants: THERABIOPHARMA INC., KYOTO UNIVERSITY
    Inventors: Hideaki KAKEYA, Masashi Kanai, Nobuaki Takahashi, Tadashi Hashimoto, Atsushi Imaizumi, Hitomi Ozawa
  • Patent number: 10742454
    Abstract: Provided is a transmission device of a single carrier frequency-domain equalization scheme having a circuit in which a cyclic prefix (CP) and an overlap margin (OM) are inserted, and a time-domain windowing processing circuit to which is input a transmission symbol into which the CP and the OM have been inserted. The time-domain windowing processing circuit multiplies an arbitrary time-domain window function and suppresses out-of-band emission. In the time-domain windowing processing circuit, a window transition length of the time-domain window function is equal to or larger than a length of the CP.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: August 11, 2020
    Assignee: KYOTO UNIVERSITY
    Inventors: Keiichi Mizutani, Hiroshi Harada, Takeshi Matsumura, Yosuke Kodama