Abstract: A method for assessing differentiation potential of cells in a culture broth in the differentiation of pluripotent stem cells into neural cells of the midbrain floor plate region, comprising: measuring a concentration of NT-3 in a culture supernatant in a culture broth obtained by culturing the pluripotent stem cells in a medium containing an inducer of differentiation into the neural cells of the midbrain floor plate region; comparing the measured concentration of NT-3 with a reference concentration; and when the concentration of NT-3 is equal to or more than the reference concentration, assessing the cells in the culture broth as capable of differentiating into the neural cells of the midbrain floor plate region, wherein the culture supernatant is a culture supernatant collected from the culture broth at any time from 48 hours to 240 hours after the start of culture of the pluripotent stem cells.

Abstract: Provided are: an antibody which specifically binds to and neutralizes USAG-1 or an antigen-binding fragment thereof; and a pharmaceutical composition containing the antibody or the antigen-binding fragment.

Abstract: An object of the present invention is to provide a method for producing T cells or NK cells, a culture medium for culturing T cells or NK cells, a method for culturing T cells or NK cells, a method for maintaining the undifferentiated state of undifferentiated T cells, and a growth promoter for T cells or NK cells, which are capable of efficiently proliferating T cells or NK cells and maintaining the state of the cells (for example, undifferentiated property). The present invention relates to a method for producing T cells or NK cells including culturing T cells or NK cells in a culture medium containing a bisbenzylisoquinoline alkaloid represented by formula (X-1) or formula (X-2) or a compound resulting from cleavage of one ether bond thereof or a pharmaceutically acceptable salt thereof, and the like.

Abstract: Technical Problem The purpose of the present invention is to provide a method which enables sex selection in a non-human animal, and enables a coming individual to have no recombination gene, and a transgenic non-human animal giving birth to individuals of only one sex, which is used in the method. Solution to Problem The present disclosure relates to a male transgenic non-human animal in which one of an X chromosome and a Y chromosome comprises an exogenous embryonic death induction gene operatively connected to a drug-responsive promoter. The present disclosure also includes a method for producing a male transgenic non-human animal for sex selection.

Abstract: The present disclosure provides an infrared sensing device having a simple structure and being capable of detecting an infrared ray. A device 300 includes a variable resistance portion 13 whose electrical resistance varies in response to an infrared ray and a detection portion that detects the variation of the electrical resistance of the variable resistance portion. The variable resistance portion satisfies at least one of i) inclusion of a material potentially absorbing an infrared ray by localized surface plasmon resonance, and ii) reception of a carrier from a carrier supply portion 23 including the above material and being in contact with the variable resistance portion, the carrier being an electron and/or a hole, the carrier being generated by irradiation of the carrier supply portion with an infrared ray.

Abstract: Disclosed is an organ sucking and grasping tool capable of reducing the height of the sucking and grasping tool, capable of reserving a viewing field for an endoscope, capable of reserving space for operations, and including a suction cup responsive to the deformation of an organ and unlikely to be detached. An organ sucking and grasping tool includes a suction tube body and a plurality of suction cups for organ suction provided at a front end portion of the suction tube body. The organ sucking and grasping tool sucks, elevates, and grasps an organ using suction force generated by the suction cups. The suction cups are held by a ring-shaped holder provided at the front end portion of the tube body, and an annular flange is provided at an open end portion of each of the suction cups.

Abstract: The present invention provides a surface treatment film that is capable of imparting durability such as wear resistance, friction resistance, chemical resistance, heat resistance, and solvent resistance to the surfaces of various substrates, and that exhibits excellent adhesion to the surfaces of the substrates. The surface treatment film is provided on the surface of a substrate. The surface treatment film has a laminated structure that includes a polymer layer (i) disposed on the surface side of the substrate and a polymer layer (ii) disposed on the polymer layer (i). The polymer layer (i) contains a first polymer derived from a polymerization initiation group-containing polymer, such as a polyester having, in a side chain, a functional group represented by formula (1) wherein R1 represents a hydrogen atom, a methyl group, or the like, R2 represents a methyl group or the like, X represents a chlorine atom or the like, Y represents O or NH, and * shows a bonding position.

Abstract: A brain measurement apparatus configured to generate an MR image and a brain's magnetic field distribution of a subject includes: an MRI module having a transmission coil configured to transmit a transmission pulse toward the subject and a detection coil configured to detect a nuclear magnetic resonance signal generated in the subject by the transmission pulse; an optically pumped magnetometer configured to detect a brain's magnetic field of the subject; a generator configured to generate the MR image based on the nuclear magnetic resonance signal detected by the detection coil and generating the brain's magnetic field distribution based on the brain's magnetic field detected by the optically pumped magnetometer; a marker displayed on the MR image generated by the generator; and a helmet-type frame to which the detection coil, the optically pumped magnetometer, and the marker are attached and which is attached to a head of the subject.

Abstract: A superconducting rotating machine, including: a stator that has a tubular stator iron core and stator windings wound around the stator iron core and generates a rotating magnetic field; a superconducting rotor having: a superconducting squirrel-cage winding that is held rotatably with the rotating magnetic field of the stator on an inner peripheral side and has one or more rotor bars and end rings each made of a superconducting material; and a rotor iron core that has a plurality of slots to accommodate the rotor bars; a pulse voltage output unit that outputs a pulse voltage to shift the superconducting squirrel-cage winding to a magnetic flux flow state; a drive voltage output unit that applies a drive voltage to the stator windings to rotationally drive the superconducting rotor, wherein the pulse voltage output from the pulse voltage output unit is superimposed on the drive voltage.

Abstract: A pigment of the present invention is a compound represented by General Formula (1) or General Formula (2) (in the above-described formulae, M is Sn or Ge, X is C or N, R1 is an alkyl group or a phenyl group, Y1 and Y2 are each hydrogen, a halogen group, a methyl group, an alkoxy group, a phenyl group, a diphenylamide group, a thiophenyl group, or a phenylethynyl group, and Z is a single bond or represented by Formula (3), where R2 is an alkyl group or a phenyl group).

Abstract: A SiC junction field effect transistor includes a SiC substrate, a first conductivity type channel region formed in the principal surface of the SiC substrate, a second conductivity type embedded gate region formed below the channel region on the principal surface side in the SiC substrate, and first conductivity type source region and drain region formed with the channel region interposed therebetween in the principal surface of the SiC substrate.

Abstract: A method is disclosed for manufacturing a structured polymeric material. In the method, a body is provided comprising a substantially homogenous precursor polymeric material. An interference pattern of electromagnetic radiation is set up within the body to form a partially cross-linked polymeric material, the interference pattern comprising maxima and minima of intensity of the electromagnetic radiation, the interference pattern thereby causing spatially differential cross linking of the precursor polymeric material to form crosslinked regions having relatively high cross linking density and non-crosslinked regions having relatively low cross linking density, the crosslinked regions and non-crosslinked regions corresponding to the maxima and minima of intensity of the electromagnetic radiation, respectively.

Abstract: A laser irradiation apparatus including: a photonic crystal surface emitting laser (PCSEL) element configured to emit a laser beam; a laser head configured to focus the laser beam emitted from the PCSEL element by a focusing lens thereof in an optical transmission path by spatial propagation; and a moving mechanism configured to irradiate the laser beam focused by the focusing lens onto an object to be irradiated with the laser beam at any irradiation position within a Rayleigh length range regardless of a beam waist position of the laser beam in an optical axis direction by a movement of the focusing lens relative to the object to be irradiated along the optical axis direction of the laser beam.

Abstract: The present disclosure includes a method of producing a retinal tissue, the method including inducing differentiation of pluripotent stem cells into a retinal tissue on a surface of a culture substrate.

Abstract: A semiconductor device includes a p-type nitride semiconductor layer, the p-type nitride semiconductor layer including an Al-containing nitride semiconductor layer and an Al-containing compound layer containing Al and C as main constituent elements and provided on the surface of the Al-containing nitride semiconductor layer.

Abstract: A brain measurement apparatus includes: a magnetoencephalograph module having a cell, a pump laser configured to emit pump light, a probe laser configured to emit probe light to a sensitivity region intersecting the pump light in the cell, an optical sensor group configured to detect a polarization plane angle of the probe light having passed through the sensitivity region, and a bias magnetic field coil configured to apply a bias magnetic field; and an MRI module having a transmission coil for transmitting an RF pulse of a predetermined frequency, and a receiver coil configured to detect a nuclear magnetic resonance signal generated by transmission of the RF pulse. The magnetoencephalograph module and the MRI module are surrounded by a magnetic shield including a soft magnetic material.

Abstract: A brain measurement apparatus includes: a magnetoencephalograph module having a cell; a pump laser configured to emit pump light; a probe laser configured to emit probe light; an optical sensor group configured to detect a polarization plane angle of the probe light having passed through the sensitivity region; a bias magnetic field coil configured to apply a bias magnetic field; and bias magnetic field gradient correction coils configured to correct a gradient of the bias magnetic field; and an MRI module having a transmission coil for transmitting an RF pulse of a predetermined frequency and a receiver coil configured to detect a nuclear magnetic resonance signal. At least one of the coil that applies a static magnetic field and the coil that applies a gradient magnetic field is configured by the same coil as the bias magnetic field coil or the bias magnetic field gradient correction coils.

Abstract: An optically pumped magnetometer includes a cell, a pump light incidence unit causing pump light to be incident on a plurality of sensitivity regions inside the cell in a first direction, a probe light incidence unit causing probe light to be incident on the sensitivity regions in a direction intersecting the first direction, bias magnetic field coils applying a bias magnetic field to the inside of the cell and determining a resonance frequency of the electron spins, an electron spin tilting unit tilting a rotation axis direction of the electron spins in a direction perpendicular to the first direction, an optical sensor detecting the probe light; and a magnetic field measuring unit measuring magnetic field strengths related to the sensitivity regions, wherein the bias magnetic field coils respectively apply a plurality of the bias magnetic fields having strengths different from each other to the plurality of corresponding sensitivity regions.

Abstract: An optically pumped magnetometer includes a cell, a pump light incidence unit causing pump light to be incident on a sensitivity region inside the cell in a first direction, a probe light incidence unit causing probe light for detecting change in electron spins to be incident on the sensitivity region in a direction intersecting the first direction, a bias magnetic field coil applying a bias magnetic field in the first direction to the inside of the cell and determining a resonance frequency of the electron spins, a gradient correction coil correcting a gradient of the bias magnetic field, an electron spin tilting unit tilting a rotation axis direction of the electron spins, an optical sensor detecting the probe light having passed through the sensitivity region, and a magnetic field measuring unit measuring a magnetic field strength related to the sensitivity region based on an output of the optical sensor.

Abstract: Provided is a method for inducing T cells for a cell-based immunotherapy, comprising the steps of: (1) providing Rag 1 and/or Rag 2 gene knockout human pluripotent stem cells bearing genes encoding a T cell receptor specific for a desired antigen, and (2) inducing T cells from the pluripotent stem cells of step (1). Further provided are a cell-based immunotherapy method that uses the T cells for the cell-based immunotherapy and an iPS cell bank for the cell-based immunotherapy.