Abstract: Provided herein are methods for the improved production of periplasmic-targeted recombinant proteins in E. coli host strains. Also provided are E. coli host strains with improved capacity for producing recombinant proteins.

Abstract: Differential Holography technology measures the amplitude and/or phase of, e.g., an incident linearly polarized spatially coherent quasi-monochromatic optical field by optically computing the first derivative of the field and linearly mapping it to an irradiance signal detectable by an image sensor. This information recorded on the image sensor is then recovered by a simple algorithm. In some embodiments, an input field is split into two or more beams to independently compute the horizontal and vertical derivatives (using amplitude gradient filters in orthogonal orientations) for detection on one image sensor in separate regions of interest (ROIs) or on multiple image sensors. A third unfiltered beam recorded in a third ROI directly measures amplitude variations in the input field to numerically remove its contribution as noise before recovering the original wavefront using a numerical in algorithm.

Abstract: A system for adjusting a cutting tool includes a cutting system having a cutting tool configured to cut material thermoformed to a dental model. The cutting system is configured to determine, based on a cut line generated for the cutting tool to cut a dental aligner from the material thermoformed onto the dental model, that the cutting tool is incapable of following the cut line. The cutting system is configured to adjust a position of the cutting tool with respect to the cut line so the cutting tool is capable of following the cut line.

Abstract: A surgical tool includes a drive housing, a drive input and input shaft rotatably mounted to the drive housing, and a drive assembly mounted to the input shaft and including an upper capstan rotatably mounted to the input shaft with a first one-way bearing, and a lower capstan rotatably mounted to the input shaft with a second one-way bearing. First and second drive cables are coupled to the upper and lower capstans and extend to an end effector of the surgical tool. Rotating the input shaft in a first angular direction rotationally disengages the lower capstan from the input shaft and drives the upper capstan in the first angular direction, and rotating the input shaft in a second angular direction rotationally disengages the upper capstan from the input shaft and drives the lower capstan in the second angular direction.

Abstract: The present disclosure provides method and apparatus for providing a summary of a multimedia document in a session. In some implementations, a message may be received from a user in a session and the session is between the user and an electronic conversational agent. The multimedia document may be obtained based at least on the message. The emotion informaion in the multimedia document may be extracted. The summary of the multimedia document may be generated based at least on the message and the extracted emotion information. A response including the generated summary of the multimedia document may be provided to the user.

Abstract: A method includes generating a query entigen group for a query in accordance with identigen rules. The query entigen group represents a most likely interpretation of the query. The method further includes obtaining an embellished entigen group from a knowledge database based on the query entigen group. The embellished entigen group substantially includes the query entigen group and a set of embellishing entigens. The method further includes selecting a set of response entigens from the embellished entigen group in accordance with a response embellishment approach to produce a response entigen group. The set of response entigens includes at least one embellishing entigen of the set of embellishing entigens. The method further includes generating a response phrase based on the response entigen group. The response entigen group represents a most likely interpretation of the response phrase.

Abstract: Methods of controlling axle torque distribution of a vehicle during steering through a curve include collecting, via a controller: input data which is representative of a plurality of vehicle inputs; vehicle data which is representative of axle torque of the front axle and axle torque of the rear axle; and constraint data which is representative of real-time constraints of the vehicle. The collected input data, vehicle data and constraint data are communicated to a predictive model. Determining, using the predictive model, whether torque adjustments are necessary. The distribution of the axle torque of the front axle and the axle torque of the rear axle is controlled, via the controller, when the torque adjustments are necessary as determined via the predictive model.

Abstract: A ball assembly for attachment to a ball mount is described. The ball assembly can include a ball post that is securable to a ball mount. A hitch ball is slidably coupled to the ball post at a ball end of the ball post. A load gauge is disposed at the gauge end of the ball post. A load transfer element is operably associated with both the hitch ball and the load gauge so as to cause a load measurement to display on the load gauge based upon a load applied to the hitch ball.

Abstract: A loyalty switch for examining loyalty messages and routing the loyalty messages to one or more loyalty hosts and examining responses and routing the responses back to stores. Such a switch has configurable number of selector handlers pool, and the switch accepts a connection from stores and reads loyalty host information from master data to establish the connection with a loyalty host and to route messages. Each selector handler in the switch has multiple store objects that contain a routing map and connection information from companies' sites and the loyalty host.

Abstract: Systems and methods of parallel uniform resource identifier resource extraction are provided. A tracking uniform resource identifier (URI) generation component can generate a first uniform resource locator (URL) that, responsive to actuation by a client computing device, causes the client computing device to send a content item identifier of a content item and a device identifier of the client computing device, via a computer network, to a records server at a first network location identified by the first URL. A resource URI generation component can generate a second URL that, responsive to actuation by the client computing device, causes the client computing device to retrieve, via the computer network, a first resource from a second network location identified by the second URL for display by the client computing device. A content item packaging component can generate the content item.

Abstract: Systems and methods for encoding multiple video streams in accordance with embodiments of the invention are disclosed. In one embodiment, a source encoder configured to encode source video as a number of alternative video streams includes a parallel processing system configured to collect statistics on source video data and write the statistics to shared memory in a first pass through the received multimedia content, determine initial encoding information for source video data and write the initial encoding information to shared memory during the first, encode the source video data in parallel using collected statistics and initial encoding information to produce a plurality of alternative video streams during a second pass, and parallel encoding processes are configured to reuse additional encoding information that has already been determined for a portion of video and to generate additional encoding information that has not already been determined for a portion of video.

Abstract: A method for developing content for a personalized non-profit venue experience using a mobile computing device, comprising: providing an interface for management of a set of multimedia assets; receiving a mapping of multimedia assets to a set of locations on a site plan for the non-profit venue; receiving metadata for the set of multimedia assets; receiving personalized interest data indicating personal philanthropic interests of a visitor to the non-profit venue; and applying a machine learning algorithm to analyze the metadata and the personalized interest data to provide, to a mobile computing device, a selection of a multimedia asset from the set of multimedia assets for consumption by the visitor.

Abstract: In a broadband wireless communication system, a spread spectrum signal is intentionally overlapped with an OFDM signal, in a time domain, a frequency domain, or both. The OFDM signal, which inherently has a high spectral efficiency, is used for carrying broadband data or control information. The spread spectrum signal, which is designed to have a high spread gain for overcoming severe interference, is used for facilitating system functions such as initial random access, channel probing, or short messaging. Methods and techniques are devised to ensure that the mutual interference between the overlapped signals is minimized to have insignificant impact on either signal and that both signals are detectable with expected performance by a receiver.

Abstract: A method and a system for separating components is disclosed. A process liquid stream, containing a first component and a second component, is passed into an expansion device. The process liquid stream is expanded such that the first component and a first portion of the second component vaporize to form a process vapor stream and a second portion of the second component freezes to form a first solid product stream. The first solid product stream passes out of the expansion device. The process vapor stream passes into a direct-contact heat exchanger against a contact liquid stream. The first portion of the second component desublimates into the contact liquid stream as a second solid product stream. The contact liquid stream and the second solid product stream leave the direct-contact heat exchanger as a slurry stream. The process vapor stream leaves the direct-contact heat exchanger as a stripped process vapor stream.

Abstract: A method and apparatus for providing a license to a client device, the license providing a key for decrypting a content instance. In one embodiment, the method comprises accepting a license request, the license request including a client identifier and an access token having an access token identifier and key request data comprising a content identifier identifying the content instance, determining if the received access token identifier is currently bound to a stored client device identifier, and temporarily binding the received access token identifier with the received client device identifier and providing the received access token for validation or returning an error without providing the received access token for validation depending upon the determination.

Abstract: A molded container assembly including a pallet, a molded container, and a plurality of connection systems. The pallet supports the molded container thereon and includes stacking alignment structure for stacking the pallet on another molded container assembly. The molded container includes a tank portion, several leg supports, and several buttresses. The tank portion includes several curved sidewalls and a fill opening. The leg supports include lower sections and upper sections that extend above the fill opening for spacing a pallet stacked on top of the molded container above the fill opening. The upper sections include pallet engaging structure for engaging pallets of at least two different types. The buttresses extend between the tank portion and the leg supports. The connection systems include washers that allow for shrinkage and expansion between the molded container and the pallet in a number of directions.

Abstract: A polymer electrolyte fuel cell (PEFC), comprises a first electrode and a second electrode, wherein the first electrode includes a coaxial nanowire electrode. In some embodiments, the coaxial nanowire electrode comprises a plurality of ionomer nanowires, and a catalyst coating that coats at least part of the ionomer nanowires. Moreover, in some embodiments, a nanowire of the plurality of ionomer nanowires and a section of the catalyst coating that coats the nanowire form two coaxial cylinders.

Abstract: A set of attributes of a particular asset of a computing environment is identified that are determined from data collected by one or more utilities in the computing environment. A criticality rating is automatically determined for the particular asset based at least in part on the set of attributes. A security activity is caused to be performed relating to the particular asset based on the automatically determined criticality rating of the particular asset.

Abstract: Described herein is a third party data management system that uses a classification algorithm trained using a machine learning process to analyze type(s) of data that will be shared with the third party to determine a risk of sharing data with the third party. Periodically data provided to a particular third party can be analyzed to identify privacy issue(s). In response to the analysis, an action to be taken with respect to the particular third party can be identified and provided to a user. In some embodiments, information from trusted news feeds can be processed using natural language processing to determine a potential privacy or security issue regarding a third party with whom data has been shared.

Abstract: Gancyclovir formulations that are ready-to-use, substantially particulate free, and stable upon storage are disclosed. Methods of manufacture and administration of such compositions are also provided.