Abstract: The present disclosure provides a method of determining a relative decrease in catalytic efficacy of a catalyst in a test sample of a catalyst solution with unknown catalytic activity. The method includes (a) mixing the test sample with a test solvent to form a test mixture and (b) measuring the increase in the temperature of the test mixture at predetermined time intervals immediately after forming the test mixture. A predetermined feature is used to determine both a test value in the increase in temperature measured in (b) and a control value in a known increase in temperature of a control mixture of the test solvent with a control sample of a control catalyst solution. The relative decrease in catalytic efficacy of the catalyst in the test sample having the unknown catalytic activity is then determined from: Relative Decrease in Catalytic Efficacy=Control Value?Test Value/Control Value.

Abstract: A composition is described comprising superparamagnetic particles. Optionally, the particles comprise microbeads. Optionally, the particles comprise nanobeads. Optionally, the particles are non-spherical particles. Optionally, the particles are non-spherical particles suitable for RNA or DNA extraction. A method is described for forming microparticles. Optionally, the method comprises using citrate precipitation. Optionally, a kit comprising one or more of the particles is described. Optionally, a kit for sample preparation for nucleic acid extraction is described comprising non-spherical microparticles or nanoparticles.

Abstract: Some embodiments described herein cover a machine learning architecture with a separated perception subsystem and application subsystem. These subsystems can be co-trained. In one example embodiment, a data item is received and information from the data item is processed by a first node to generate a sparse feature vector. A second node processes the sparse feature vector to determine an output. A relevancy rating associated with the output is determined. A determination is made as to whether to update the first node based on update criteria associated with the first node, wherein the update criteria comprise a relevancy criterion and a novelty criterion. The second node is updated based on the relevancy rating.

Abstract: A multi-layer cap shingle for installation along a ridge, hip, or rake of a roof includes a forward exposure area and a rear headlap area. The multi-layer cap shingle includes at least two layers of shingle material, a top layer and a bottom layer each having opposed edges. The layers are bonded together with patches of lamination adhesive adjacent their opposed edges. The bottom layer is configured with a deformation-absorbing mechanism such as a pair of slots extending from a forward edge reawardly inboard of the lamination adhesive patches. When the multi-layer cap shingle is bent over a roof ridge, the slots of the bottom layer of shingle material narrow in width to account for the fact that the bottom layer must bend around an arc of slightly smaller radius than the top layer of shingle material.

Abstract: Connector housings and connector assemblies for mechanically connecting a pin to a housing with or without electrical conductivity. A connector housing can be formed by attaching two housing sections together with one or both housing sections formed at least in part by a stamping process. The connector housing can have an outer contour, such as an outer perimeter, with one or more sides and with a joining section connecting two adjacent sides together. The two or more sides can be used for handling, aligning, and/or assembling of the connector housing to a cavity.

Abstract: By individually metering and dispensing specific volumes and/or weights of each component of a dosage, an amount of the components for each dose is secured with very high accuracy. A method for dosing a pharmaceutical product in a sealed container, such as, for example, a packet, sachet, blister pack, or other unit dose form. The dosage may include a first component that is a thickening agent and a second component that is an active ingredient. The thickening agent serves as a carrier that allows the active ingredient to dissolve in the mouth and be swallowed without the administration of water. The method includes providing the first component by measuring the volume or weighing the mass of the first component and measuring the volume or weighing the mass of the second component. Subsequent components may also be individually measured or weighed before being added to a package.

Abstract: The present invention provides a composition comprising a mixture of an exogenous ketone body, an exogenous NAD modulator and a methyl donor. Typically, exogenous NAD modulator is an exogenous nicotinamide adenine dinucleotide (NAD) precursor. The present invention also provides a method of using such a composition for treating various clinical conditions, including metabolic disorders and neurocognitive impairments. The compositions of the invention can also be used to improve human performance in various competitive or environmental conditions.

Abstract: Systems and methods for modifying a municipal fixture to affix endpoint devices, provide a power to such devices, and managing network traffic between and among such devices, including managing upstream transmission and efficiently propagating desired state changes through the network. The systems and methods described herein generally use a plurality of mesh radio transmitters which are configured for peer-to-peer data exchange to propagate system state changes to one or more uplink gateways. The gateways may then aggregate this data and transmit it over a wide area network to a server or server farm for processing, analysis, and other use. That data may also be viewed in real time by user devices, and instructions and commands may also be relayed to the individual IoT devices in the mesh network via such user devices.

Abstract: A system includes a full-color electronic display, an eye-tracking module arranged to track an eye of a viewer of the display during operation of the system, at least one programmable processor, and a machine-readable medium storing instructions that, when executed by the at least one programmable processor to perform operations, including: (i) assessing uncorrected image data with one or more image frames, including determining an initial color of pixels in an image frame; (ii) assessing, based on data from the eye-tracking module, a location on the display where the viewer's eye is looking; (iii) modifying a color of red pixels from its initial color to a modified red color based on the location of the pixel relative to the location on the display where the viewer's eye is looking and the initial color of the pixel; and (iv) displaying, on the display, the image frames in which the one or more pixels have the modified color and other pixels have their initial color.

Abstract: A system for self-fulfillment of an alimentary instruction set based on vibrant constitutional guidance using artificial intelligence. The system includes at least a server designed and configured to receive training data. The system includes a diagnostic engine operating on the at least a server and configured to record at least a biological extraction from a user and generate a diagnostic output. The system includes a plan generator module operating on the server designed and configured to generate a comprehensive instruction set associated with the user. The system includes an alimentary instruction set generator module operating on the at least a server designed and configured to generate an alimentary instruction set. The system includes a fulfillment module operating on the at least a server designed and configured to receive a user entry containing at least an alimentary self-fulfillment action.

Abstract: Systems, methods, and computer-readable storage devices are disclosed for improved audio feature discovery using a neural network. One method including: receiving a trained neural network model, the trained neural network configured to output an audio feature classification of audio data; deconstructing the trained neural network model to generate at least one saliency map, the at least one saliency map providing a successful classification of the audio feature; and extracting at least one visualization of the audio feature the trained neural network model relies on for classification based on the at least one saliency map.

Abstract: A display mount for connecting electronic devices includes a body, a display support, and a movable arm connected to the body and the display support. The body has a lower surface and an upper surface. The body further includes a controller connection mechanism. The arm is positioned above the upper surface to hold the display support above the body and opposite the lower surface.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for receiving graph data representing an input graph comprising a plurality of vertices connected by edges; generating, from the graph data, vertex input data representing characteristics of each vertex in the input graph and pair input data representing characteristics of pairs of vertices in the input graph; and generating order-invariant features of the input graph using a neural network, wherein the neural network comprises: a first subnetwork configured to generate a first alternative representation of the vertex input data and a first alternative representation of the pair input data from the vertex input data and the pair input data; and a combining layer configured to receive an input alternative representation and to process the input alternative representation to generate the order-invariant features.

Abstract: Control of a prompt for a credential to unlock a computer-readable storage device is provided. Some embodiments permit identifying a component that encrypted the computer-readable storage device and, depending on the identified component, prompting for such a credential. One embodiment can determine that a firmware encrypted the computer-readable storage device and can prompt for a password, for example, to unlock the computer-readable storage device during a boot-up process performed by the firmware. Other embodiments can determine that an operating system encrypted the computer-readable storage device, and can avoid the presentation of a prompt for a password, for example, during a boot-up process performed by the firmware. The computer-readable storage device can be a self-encrypting drive (SED) or another type of disk drive.

Abstract: A method comprising administering to a subject a composition comprising an isolated microRNA having a sequence selected from the group consisting of miR-19a-3p (SEQ ID NO:1); miR-103a-3p (SEQ ID NO:2); miR-106b-5p (SEQ ID NO:3); miR-146a-5p (SEQ ID NO:4); miR-223-5p (SEQ ID NO:5); miR-4497 (SEQ ID NO:6); miR-1303 (SEQ ID NO:7); miR-619-5p (SEQ ID NO:8); miR-1273f (SEQ ID NO:9); miR-7851-3p (SEQ ID NO:10); a functional variant thereof; and combinations thereof.

Abstract: Systems and methods for application specific integrated circuit design using Chronos Links are disclosed. A Chronos Link is an ASIC on-chip and off-chip interconnect communication protocol that allows interfaces to transmit and receive information. The protocol may utilize messages or signals to indicate the availability and/or readiness of information to be exchanged between a producer and a consumer allowing the communication to be placed on hold and to be resumed seamlessly. A method includes inserting gaskets and channel repeaters connected to interfaces of multiple intellectual property (IP) blocks in order to replace traditional links with Chronos Links; performing simplified floorplanning; performing simplified placement; performing simplified clock tree synthesis (CTS) and routing; and performing simplified timing closure.

Abstract: A load control system for controlling an electrical load in a space of a building occupied by an occupant may include a controller configured to determine the location of the occupant, and a load control device configured to automatically control the electrical load in response to the location of the occupant. The load control system may include a mobile device adapted to be located on or immediately adjacent the occupant and configured to transmit and receive wireless signals. The load control device may be configured to automatically control the electrical load when the mobile device is located in the space. The load control system may further comprise an occupancy sensor and the load control device may automatically control the electrical load when the occupancy sensor indicates that the space is occupied and the mobile device is located in the space.

Abstract: Computing environments employing Artificial Intelligence (AI) are disclosed for enabling network operators to optimize messaging performance, particularly 5G (and future 6G) messaging performance, in real-time. For example, AI structures can assist in the selection and optimization of modulation tables. Three development phases are described: network data acquisition including faults experienced under various network conditions, AI structure tuning for accurate prediction of performance, and implementation of an algorithm based on the AI structure. Network operators can use the algorithm to compare predicted performance metrics according to various operating conditions, such as available modulation tables, and thereby select operating parameters for improved message reliability and throughput. The algorithm can also be used to adjust network variables, such as particular amplitude or phase levels in modulation tables.

Abstract: Systems, methods, and computer-readable media are described herein to model divergent beam ray paths between locations on a roof (e.g., of a structure) and modeled locations of the sun at different times of the day and different days during a week, month, year, or another time period. Obstructed and unobstructed divergent beam ray paths are identified. Unobstructed divergent beam ray paths contribute to the calculation of a solar irradiance value for each location on the roof. Divergent beam ray paths, such as cones or pyramid ray paths, allow for sparse or lower-resolution spatial and/or temporal sampling without sacrificing obstacle detection.

Abstract: Techniques for providing eyewear with electrical components are disclosed. The electrical components can provide electrical technology to eyewear (e.g., eyeglasses) without having to substantially compromise aesthetic design principles of the eyewear. Often, the electrical components can be attached to the eyewear as an after-market enhancement. The electrical components can operate independently or together with other electrical components provided elsewhere. In some embodiments, tethered electrical components can be coupled to electrical components in or attached to a pair of eyeglasses. Tethered electrical components, alone or in combination with eyeglass electrical components can be used for a variety of different applications and uses.