Abstract: The subject disclosure relates to compounds and compositions including chemotherapy agents and/or radiation therapy with bipolar trans carotenoids, and the use of such compounds for the treatment of various cancers including pancreatic and brain cancers.

Abstract: The present disclosure relates to a surgical drape to be used in conjunction with a surgical procedure, and more specifically to a surgical drape that includes one or more of the following: (1) a patient drape for use with a standalone non-draped image acquisition device; (2) a patient drape for use with a standalone non-draped image acquisition device with image guidance navigation technology; (3) the means to provide temporary sterile coverage of an underlying sterile field; (4) the means to provide sterile separation of at least a portion, if not the entire temporary sterile coverage; and (5) the means to provide covering of the undersurface of the operating surface and enclosing any suspended medical devices, wires, cables, tubes, etc.

Abstract: Systems and methods for rollback of model-based provisioned network device configuration including a memory capable of storing a model-based provisioned data template that includes a data template sequence. Data associated with a request to transmit a target object request message are received and transmitted following a retrieval message that determines pre-configuration data of the target device. The pre-configuration data is stored and the target object request message is sent specifying CRUD semantics. A notification is received indicating an outcome of the execution and, if the execution outcome is unsuccessful, a rollback stack is retrieved that specifies CRUD semantics and the pre-configuration parameters are retrieved to restore the target device to a pre-request state. If the execution outcome is successful, a second target object request message is retrieved from a list of target devices.

Abstract: The present disclosure provides for methods of treating or preventing a cardiovascular disorder and/or a related pulmonary disorder in a subject. In certain embodiments, the method comprises administering a therapeutically effective amount of an inhibitor of Glucose-6-phosphate dehydrogenase (G6PD), or a pharmaceutically acceptable salt, non-salt amorphous form, solvate, poly-morph, tautomer or prodrug thereof.

Abstract: Systems and methods are provided for preventing a loss of throughput data connectivity from one or more active autonomous vehicles of the fleet communicating with a back office network by: collecting an average aggregate of the throughput data from the one or more active AVs communicating with the back office network; updating a set of records in a throughput data table corresponding to a plurality of mapped AV routes for the one or more active AVs, by processing a throughput data table record in the temporary buffer of updated throughput data to eliminate identified duplicate or out-of-date throughput data recorded in the throughput data table; and determining, by the back office network, whether one or more of the AV route segments or the final drop-off location exhibits the effect of an instance of the loss of throughput data connectivity between the AV and the back office network.

Abstract: In some examples, a surface, such as a desktop, in front or around a portable electronic device may be used as a relatively large surface for interacting with the portable electronic device, which typically has a small display screen. A user may write or draw on the surface using any object such as a finger, pen, or stylus. The surface may also be used to simulate a partial or full size keyboard. The use of a camera to sense the three-dimensional (3D) location or motion of the object may enable use of above-the-surface gestures, entry of directionality, and capture of real objects into a document being processed or stored by the electronic device. One or more objects may be used to manipulate elements displayed by the portable electronic device.

Abstract: Device assisted CDR creation, aggregation, mediation and billing is provided. In some embodiments, device assisted CDR creation, aggregation, mediation and billing for a wireless network includes collecting device generated service usage information for one or more devices in wireless communication on the wireless network; and providing the device generated service usage information in a syntax (e.g., a device assisted charging data record (CDR)) and a communication protocol (e.g., 3GPP, 3GPP2, or other communication protocols) that can be used by other network devices to augment or replace network generated service usage information for the one or more devices in wireless communication on the wireless network.

Abstract: Methods and systems for operating an engine that includes an after treatment system are described. In one example, traffic data and navigation system data are a basis for deciding whether or not to increase heat output of an engine to ensure operation of the after treatment system. In particular, one or more actuators may be adjusted to minimize fuel consumption and/or reduce feedgas emissions while generating sufficient heat to maintain after treatment system operation.

Abstract: A light-emitting device is disclosed that includes a substrate; a semiconductor structure on the substrate, a wavelength conversion element on the substrate, opposite the semiconductor structure; an insulating side coating around the semiconductor structure; and a reflective side coating around the wavelength conversion element and the substrate, the reflective layer being stacked over the insulating side coating, the reflective side coating having a first surface that is over a second surface of the insulating side coating.

Abstract: Methods for manufacturing insulating glass units (IGUs) include providing an unsealed IGU assembly that has first and second sheets of glass material and at least one spacer frame between the first and second sheets and sealed to at least one of the first and second sheets. The unsealed IGU assembly defines an interpane space and an IGU passage providing fluid communication between the interpane space and an environment external to the interpane space. In some cases the method includes positioning a filling device next to the IGU passage and introducing a gas into the interpane space through the IGU passage using the filling device. In some cases the method includes delivering a sealing material or sealing structure to the IGU passage with the filling device to seal the interpane space. Corresponding systems for manufacturing IGUs are also provided.

Abstract: The present invention provides a method for the production of a flavor-enhancing composition, the method comprising the steps of: i) providing a dairy liquid; ii) nanofiltrating the dairy liquid to obtain a nanofiltration permeate; iii) concentrating the nanofiltration permeate by reverse osmosis and/or evaporation to produce a flavor-enhancing composition, the flavor-enhancing composition comprising at least 50 wt % lactose by dry weight and having a K:Na ratio of at least 2:1, wherein nanofiltrating the dairy liquid uses a membrane having a molecular weight cut-off of from 300 Da to 800 Da.

Abstract: An aerosol-generating device includes an interface, one or more pairs of conductors, and electrical circuitry. The interface is configured to receive at least a portion of a consumable. The consumable comprises one or more conductive portions arranged to identify the consumable. The one or more pairs of conductors define at least a portion of one or more circuits. The one or more pairs of conductors are selectively electrically couplable with the one or more conductive portions of the consumable if the consumable is received by the interface. The electrical circuitry is configured to identify the consumable based on completion of the one or more circuits defined by the one or more pairs of conductors and the one or more conductive portions if the consumable is received by the interface.

Abstract: A method of improving the fatigue life of a superelastic medical device includes applying a compressive stress to a fatigue critical location of a medical device comprising a superelastic nickel-titanium alloy, where the compressive stress induces a compressive strain of greater than 9% in the fatigue critical location. After inducing the compressive strain, the compressive stress is released. A tensile stress is applied to the fatigue critical location of the medical device, where the tensile stress induces a tensile strain of greater than 9% in the fatigue critical location. After inducing the tensile strain, the tensile stress is released. After application and release of each of the compressive stress and the tensile stress, the fatigue critical location includes a non-zero amount of residual strain, and the medical device may exhibit improved fatigue properties.

Abstract: A processor enabled method in a mobile device includes configuring a WiFi radio controller of the mobile device with a WiFi service set identifier of a search detector and configuring a Bluetooth connection configuration of a search detector. The method also includes responsive to a rescue trigger, enabling the device to exit a low power mode while awaiting a connection attempt from a Bluetooth radio via the configured Bluetooth connection configuration. The method also includes upon receiving the connection attempt, powering up the WiFi radio and attempting to connect to the configured WiFi service set identifier.

Abstract: Described are a system and method that “reads” cancer tumors real time and custom delivers individualized bioelectric therapy to the patient. For example, the system reads a cancer tumor, and based upon this read, delivers to the subject “a confounding signal” to jam communication within that tumor. A cancer tumor may change its communication patterns and the therapy is designed to change with these patterns, attempting to always jam the relevant communication signaling pathway. The described system includes parameters not tied to communication jamming, which should also be customized to induce apoptosis to the cancer tumor. Such parameters include signals for starving a cancer tumor of blood supply and signals for changing the cancer tumor's surface proteins and/or charge so that the immune system attacks the cancer tumor.

Abstract: A tissue expander having an integrated drain includes an outer shell having an opening and one or more drainage holes. An injection port is disposed in the opening of the shell and forms a fluid-tight seal with the shell. The injection port includes a needle guard having a needle guard base with a top surface, and a barrier membrane that overlies the top surface of the needle guard base. The barrier membrane defines an inflation chamber located between the top surface of the needle guard base and a bottom surface of the barrier membrane, and a drainage chamber overlying a top surface of the barrier membrane. The tissue expander includes one or more inflation ports that are in fluid communication with the inflation chamber for inflating and deflating the outer shell with a first fluid. A drainage conduit is in fluid communication with and extends between the drainage chamber and the one or more drainage holes for draining a second fluid from outside the shell.

Abstract: Methods, systems, and computer programs are presented for managing electronic devices with autonomous wireless authentication. In one example, the security system includes one or more computer processors, a memory, and a communication channel configured to be coupled to an electronic system. The security system further includes a radio frequency (RF) transceiver configured to receive user-authentication information from a wireless device, and an authentication subsystem for authenticating a user. The authentication subsystem enables the use of the electronic system based on the received user-authentication information. Further, the authentication subsystem sends, over the communication channel, an enable command to the electronic system after the user is authenticated, and the electronic system is not operable until the enable command is received.

Abstract: A tool (10) for assisting an optician in removing lenses (42) from or inserting lenses into eyeglass frames (44) includes an elongated block of substantially rigid material (12) having a forward working end (14) and a rearward free end (16) opposite the working end, the portion between the free end and the working end functioning as a handle to be grasped by a person's hand. A first recess (24) is formed in the bottom surface (22) of the block along with a first curved surface (26) and a first hook (28). The first curved surface includes a rearward facing pointed edge (27). Similarly, a second recess (36) is formed in the top surface (20) of the block along with a second curved surface (38) and a second hook (40). The hooks (28, 40) are adapted to rest against the edge (46) of the frame (44) as the pointed edge (27) or the second curved surface (38) presses the lens (42) out of or into the frame (44) as the free end (16) of the tool is rotated.

Abstract: Embodiments of the present invention relate to an improved stimulation device. Embodiments of the improved stimulation device includes a cup and a driver. The cup has a cavity surrounded by a rim. The driver comprises a plate disposed on an underside of the cup, a cam disposed adjacent to the plate, and a motor mechanically coupled to the cam. The driver comprises a cam pin affixed to the cam, and a bearing rotatably disposed on the cam pin. The bearing is mechanically coupled to a lifter. The lifter is mechanically coupled to a linear bearing, enabling a smooth reciprocating back-and-forth motion from the rotation of the motor. A top of the cup swells and unswells during an operation cycle of the driver.