Abstract: An interatrial shunt device includes an opening main body. The opening main body includes an opening component for penetrating the atrial septum and expanding the atrial septal tissue to form an opening. An ablation mechanism that may damage the tissue activity at the opening of the atrial septum is disposed where the opening component contacts the atrial septal tissue. An interatrial shunt system includes the interatrial shunt device, a control mechanism of the interatrial shunt device, and an ablation power source.

Abstract: A neutron capture therapy system capable of eliminating amyloid ?-protein includes a neutron capture therapy device and a compound capable of specifically binding to the amyloid ?-protein having a nuclide with a large thermal neutron capture cross section. The neutron capture therapy device includes a neutron source, a beam shaping assembly and a collimator, the neutrons released by the neutron source pass through the beam shaping assembly and are slowed into a neutron beam within a certain energy range. The neutron beam irradiates the compound, and the energy generated by the reaction thereof can destroy the structure of the amyloid ?-protein. The neutron capture therapy system can specifically eliminate the amyloid ?-protein, and reduce the damage to the tissues surrounding the amyloid ?-protein.

Abstract: A thrombus filter has a sheath, a thrombus intercepting net having an intercepting port, and an overfill prevention umbrella being a meshed structure that always surrounds the entire thrombus intercepting net. The overfill prevention umbrella has an umbrella stand and an umbrella surface, and is self-biased such that, at body temperature, the umbrella surface is configured to always converge towards the center of the intercepting port. The thrombus filter assumes a first position when the thrombus intercepting net is released from the sheath, where the distal opening of the overfill prevention umbrella is pushed open by the intercepting port. The thrombus filter assumes a second position when the thrombus intercepting net is retrieved into the sheath, where the umbrella surface converges towards the center of the intercepting port, and the open end of the umbrella surface is constricted to prevent the thrombus from escaping.

Abstract: Provided is a geometric model establishment method based on medical image data, including: a step of reading medical image data; a step of defining a tissue type by a conversion relationship between the medical image data and the tissue type; a step of deciding the number of tissue clusters; a step of defining a tissue density by a conversion relationship between the medical image data and the density; a step of establishing 3D encoding matrix with information about the tissue and the density; and a step of generating a geometric model. According to a conversion relationship between medical image data and a tissue type, the number of tissue clusters can be determined according to actual requirements, so that the tissue type, the element composition and the density are provided more accurately, and an established geometric model is better matched to the real situation reflected by the medical image data.

Abstract: An instrument and method for tissue thermotherapy including an inductive heating means to generate a vapor phase media that is used for interstitial, intraluminal, intracavity or topical tissue treatment. In one method, the vapor phase media is propagated from a probe outlet to provide a controlled vapor-to-liquid phase change in an interface with tissue to thereby apply ablative thermal energy delivery.

Abstract: Provided is a compound for specifically binding to amyloid ?-protein. The compound has thereon a nuclide with a large thermal neutron capture cross section and the compound is capable of specifically binding to the amyloid ?-protein. The property of the compound allows it to be used in conjunction with a neutron capture therapy device to eliminate amyloid ?-protein. Similarly, when the compound is labelled with radioactive element 11C, the compound can also be used in conjunction with PET/CT for determining the part of the brain where amyloid ?-protein is deposited, for diagnosing Alzheimer's disease. Also disclosed is a preparation process for the compound. The beneficial effect of the present disclosure is to make the therapy and diagnosis of Alzheimer's disease more targeted by providing the compound for specifically binding to amyloid ?-protein.

Abstract: The invention relates to a recalibration device (1) used during the acquisition of images of an anatomical area of a patient during robot-assisted surgery, including a body (3) made of radxoliacent material, which comprises fiducial markers (9) made of radiopaque material, said body {3) having a bearing surface (7) intended to be manually placed on a surface of said anatomical area of the patient. According to the invention, said fiducial markers (9) are arranged in a specific geometrical pattern enabling a certain detection of the positioning and orientation of the recalibration device (1) in a three-dimensional digital model built from the images derived from the acquisition of the anatomical area.

Abstract: This invention relates to a novel surgical device scalable to small dimensions for thermally-mediated treatments or thermoplasties of targeted tissue volumes. An exemplary embodiment is adapted for fusing, sealing or welding tissue. The instruments and techniques utilize a thermal energy delivery means, for example an electrical energy source, to instantly elevate the temperature of a biocompatible fluid media within an electrically insulated instrument portion. The altered media which may then be a gas is characterized by a (i) a high heat content, and (ii) a high exit velocity from the working end, both of which characteristics are controlled to hydrate tissue and at the same time denature proteins to fuse, seal, weld or cause any other thermally-mediated treatment of an engaged tissue volume—while causing limited collateral thermal damage and while totally eliminating electrical current flow the engaged tissue volume.

Abstract: The robotic device for positioning a surgical instrument relative to the body of a patient includes a first robotic arm with a device for rigidly connecting to at least one surgical instrument, a device for anatomical realignment of the first arm by realigning an image that is of an area of the anatomy of the patient, and a device for compensating the movements of the first arm on the basis of detected movements. One version of the device includes at least one second robotic arm having sensors for detecting inner movements of the anatomical area, and a device for controlling the positioning of the first arm relative to sensed inner movements and to the outer movements induced in the second arm.

Abstract: An artificial chordae tendineae includes a chordae tendineae main body with at least one end connected to a fixing member. A side of the fixing member facing away from the chordae tendineae main body is provided with a puncturing connection member. An artificial chordae tendineae implantion system includes a clamping device, a puncturing device including a puncture needle, the artificial chordae tendineae, and a pushing device including a pushing shaft. The puncturing device and the clamping device are received in the pushing shaft. A proximal clamp of the clamping device is provided at a distal end of the pushing shaft. A distal clamp of the clamping device is provided at a distal end of the clamping push rod. A distal end of the puncture needle is provided with a tapped straight tip. The artificial chordae tendineae is received in the clamping device. The fixing member corresponds to the puncture needle.

Abstract: An artificial chordae tendineae implantation system includes a clamping device, a puncture device, a pushing device, and a detection device. The pushing device includes a pushing shaft. The clamping device includes a clamping push rod that receives an artificial chorda tendineae, and a distal clamp and a proximal clamp for cooperatively clamping a valve leaflet. The detection device includes one probe that is movably disposed in the pushing shaft. A probe outlet is provided at one of a clamping surface of the proximal clamp and a clamping surface of the distal clamp, and a probe accommodation chamber corresponding to the probe outlet is provided at the other one. When the clamping device is closed, the distal end of the probe protrudes from the probe outlet and is accommodated in the probe accommodation chamber, and whether the valve leaflet is clamped is detected.

Abstract: Embodiments of the present application provide a radiofrequency ablation catheter and a radiofrequency ablation system. The radiofrequency ablation catheter includes: a catheter body; a ring electrode, annularly provided at a head of the catheter body; a location sensor, provided in the catheter body; and an ablation needle, provided in the catheter body and capable of moving forward or backward. The ablation needle, when applied, pushes out from the head of the catheter body and penetrates into a lesion tissue. The embodiments of the disclosure enable an accurate location of the lesion position and the puncture into lesion for performing radiofrequency ablation therapy, so as to achieve the targeted precise ablation therapy and reduce the damage to normal tissues.

Abstract: The present invention relates to a mechanical system for stabilization on the floor for vehicles on castors (for example a surgical assistance robot used in an operating room) that can adopt two stable states, i.e. disengaged, the vehicle resting on the castors, and activated, the vehicle being immobilized on the floor, respectively. According to the invention, the stabilization system comprises: feet for resting on the floor, movable between a first retracted position, at a distance from the floor, and a contact position ensuring the immobilization of the vehicle through mechanical friction against the floor; means for mechanically controlling said supporting feet, said control means being movable between two stable positions corresponding to the activated and disengaged states; mechanical means for transmitting the displacement of the control means simultaneously to all the supporting feet.

Abstract: In order to improve flux and quality of neutron sources, the disclosure provides a beam shaping assembly for neutron capture therapy includes: a beam inlet; a target, wherein the target has nuclear reaction with an incident proton beam from the beam inlet to produce neutrons; a moderator adjoining to the target, wherein the neutrons are moderated by the moderator to epithermal neutron energies, the moderator includes a main body and a supplement section surrounding the main body, the main body and the supplement section form at least a tapered structure; a reflector surrounding the moderator; a thermal neutron absorber adjoining to the moderator; a radiation shield arranged inside the beam shaping assembly, wherein the radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation; and a beam outlet.

Abstract: Disclosed is a method for evaluating an irradiation angle of a beam, including a step of sampling the irradiation angle of the beam, wherein the irradiation angle of the beam is defined as being the direction of the vector of the irradiation point of the beam to the pre-set point of the tumor; and a step of calculating the track of the beam passing through the organs, wherein it is determined whether the tumor is fully covered within the effective treatment depth, and if so, entering the steps of calculating the evaluation coefficient, recording the irradiation conditions and calculating the results, and returning to the step of sampling the irradiation angle of the beam; and if not, entering the step of giving the worst evaluation coefficient and returning to the step of sampling the irradiation angle of the beam.

Abstract: A shielding material for shielding radioactive ray and preparation method thereof. The shielding material consists of water, a cementing material, a fine aggregate material, a coarse aggregate material and an additive, wherein the fine aggregate material consists of a borosilicate glass powder and a barite sand, and the coarse aggregate material consists of a barite. A content of boron element in the borosilicate glass powder accounts for 0.5%-1% of the total weight of the shielding material. A content of barium sulfate in the barite sand and the barite accounts for 71%-75% of the total weight of the shielding material. Other contents include water, the cementing material and the additive, and a sum of contents of all components is 100% total weight of the shielding material.

Abstract: The present disclosure relates to a ligation device, an unlocking method, and a ligation instrument. The ligation device may include a clip and a limiting tube. A distal end of the clip may be used for ligation. The limiting tube may be provided with an accommodation channel, and a proximal end of the clip may be connected with the accommodation channel, and the proximal end of the clip may move into or out of the limiting tube. The clip may be provided with a locking portion, and the limiting tube may be provided with a locking position that is matched with the locking position. When the locking portion is locked with the locking position, the locking portion may be unlocked from the locking position by operating the locking portion. Alternatively, the clip may be provided with an unlocking portion that is coupled with the locking portion. The locking portion may be unlocked from the locking position by operating the unlocking portion.

Abstract: A beam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The material of the moderator is subjected to a powder sintering process using a powder sintering device so as to change powders or a power compact into blocks. The reflector leads the neutrons deviated from the main axis back. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: Degradable bioprostheses made of collagen-based material having amine-based and ester-based crosslinks are provided, as are methods for their formation and use. Some embodiments of the present invention are directed towards a method of controlling the ratio of amine-based crosslinks to ester-based crosslinks within a collagen-based material to provide a tailorably crosslinked collagen-based material. Some embodiments provide a method of making a degradable bioprosthesis involving controlling crosslinking to afford a degradable bioprosthesis that is partially crosslinked. By controlling the ratio of amine-based to ester-based crosslinks, by controlling the level of crosslinking, or by controlling both of these features, degradable bioprostheses with tailored degradation rates can be synthesized. Some embodiments of degradable bioprostheses have degradation rates that are tailored to allow their use in particular medical applications.