Abstract: Abeam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam defining a main axis, a moderator adjoining to the target, a reflector surrounding the moderator, a thermal neutron absorber adjoining to the moderator, a radiation shield arranged inside the beam shaping assembly and a beam outlet. The neutrons are moderated to epithermal neutron energies. The reflector leads the neutrons deviated from the main axis back, and a gap channel is arranged between the moderator and the reflector. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid overdosing in superficial normal tissue during therapy. The radiation shield is used for shielding leaking neutrons and photons so as to reduce dose of the normal tissue not exposed to irradiation.

Abstract: A left atrial appendage occluder with advanced connection manner and a manufacturing method thereof are provided. The left atrial appendage occluder includes a sealing portion and an anchoring portion. Each of the sealing portion and the anchoring portion is provided with a connection part formed by converging a corresponding shape of the sealing portion or the anchoring portion respectively. The connection parts of the sealing portion and the anchoring portion extend toward each other to be fixed and misaligned with each other.

Abstract: An instrument and method for tissue thermotherapy including an inductive heating means to generate a vapor phase media that is used for interstitial, intraluminal, intracavity or topical tissue treatment. In one method, the vapor phase media is propagated from a probe outlet to provide a controlled vapor-to-liquid phase change in an interface with tissue to thereby apply ablative thermal energy delivery.

Abstract: A left atrial appendage occluder for improving sealing effect and a manufacturing method thereof are provided. The left atrial appendage occluder includes a sealing portion and an anchoring portion coupled to the sealing portion. The sealing portion and the anchoring portion abut against each other. A tight connection between the sealing portion and the anchoring portion can be achieved by applying a pre-tightening force, such that the left atrial appendage occluder can be better attached to and occlude the left atrial appendage after being release.

Abstract: Methods, systems and devices for applying energy to tissue, and more particularly relates to a system for ablating or modifying structures in a body with systems and methods that generate a flow of vapor at a controlled flow rate for applying energy to the body structure.

Abstract: Systems and methods are described herein for resurfacing bones, and in particular, for detecting and resurfacing one or more femoroacetabular impingements (FAIs). A FAI resurfacing controller may be used to perform this detecting and resurfacing of FAIs. The FAI resurfacing controller may include a bone model generator to receive bone imaging and to generate a model of at least one osteophyte and of a surface of a native bone surrounding the at least one osteophyte. The FAI resurfacing controller may include an osteophyte identifier to set a virtual 3D boundary surface between native bone surface and the at least one osteophyte. The FAI resurfacing controller may include a resurfacing navigator to generate and output a navigation file. The navigation file may include the model with the 3D boundary surface between native bone surface and the at least one osteophyte.

Abstract: Embodiments of the present application disclose a radiofrequency ablation catheter and a system. The radiofrequency ablation catheter includes: a catheter body; a localization sensor fixedly arranged inside the catheter body; and ablation electrodes fixedly arranged on the outer surface of the catheter body and used for generating radiofrequency currents, wherein the localization sensor generates a current signal in response to a localization magnetic field of a space where the localization sensor is located, and outputs the current signal to a control system outside the radiofrequency ablation catheter, so as to enable the control system to determine a position of the radiofrequency ablation catheter. The radiofrequency ablation catheter and system provided by the embodiments of the present application may help the ablation electrodes to be placed in the lesion positions more accurately.

Abstract: The present disclosure relates to an end effector instrument. The end effector instrument may include an end effector device. The end effector device may include a clip and a resilient portion including a connecting hole and a limiting convex. The end effector instrument may further include a delivery device including a sheath and a shaft. The sheath may include a passage that accommodates the shaft. A distal end of the shaft may include a connecting end. The sheath may include a limiting concave. The connecting end may extend into or exit from the connecting hole when the sheath is set outside the resilient portion: when the connecting end extends into the connecting hole, the resilient portion may expand outward, and the limiting convex may extend into the limiting concave; when the connecting end exits from the connecting hole, the resilient portion may rebound, and the limiting convex may exit from the limiting concave.

Abstract: The present invention relates to a device (3) intended to be attached to or interconnected with a medical implant (1), and intended to be attached to or interconnected with a catheter (5), the catheter (5) being intended for implanting the implant (1). The invention further relates to a catheter (5) suited for receiving at least one such device (3) and to a method.

Abstract: In order to provide a neutron therapy apparatus which give multi angles neutron beam irradiation, the neutron therapy apparatus includes: a beam shaping assembly including a moderator and a reflector surrounding the moderator, wherein the moderator moderates neutrons to a predetermined energy spectrum and the reflector guides deflected neutrons back to enhance the neutron intensity in the predetermined energy spectrum; a neutron generator embedded inside the beam shaping assembly, wherein the neutron generator generates neutrons after irradiated by an ion beam; at least a tube for transmitting the ion beam to the neutron generator, wherein the tube defines at least an axis; deflection magnets for changing the transmission direction of the ion beam; a collimator for concentrating neutrons; and an irradiation room for receiving a irradiated object, wherein the beam shaping assembly rotates around the axis of the tube.

Abstract: An instrument and method for tissue thermotherapy including an inductive heating means to generate a vapor phase media that is used for interstitial, intraluminal, intracavity or topical tissue treatment. In one method, the vapor phase media is propagated from a probe outlet to provide a controlled vapor-to-liquid phase change in an interface with tissue to thereby apply ablative thermal energy delivery.

Abstract: A wound closure device for closing a surgical wound in a tissue, wherein the wound closure device includes a first jaw, a second jaw and a handle. The first jaw is arranged for receiving a first cartridge including a plurality of slots for holding wound closers and wherein the second jaw is provided with a plurality of tracks. The plurality of tracks guide a respective one of the male ends and a respective one of the female ends towards each other and to an interlocked state where the respective one of the male ends and the respective one of the female ends are interlocked with each other.

Abstract: A heart valve assembly has a heart valve assembly that has a wire frame comprising an anchor section, a generally cylindrical valve support section, and a neck section that transitions between the anchor section and the valve support section. The wire frame includes a plurality of supports extending radially outwardly in an annular manner about an upper end of the valve support section, and the anchor section has an annular flange that extends radially therefrom, so that an annular space is defined between the annular flange and the annular supports for receiving or capturing the native annulus when the heart valve is deployed. The heart valve assembly also includes a leaflet assembly having a plurality of leaflets that are stitched to the valve support section and which are positioned on an inflow side of the neck section.

Abstract: The present invention provides a valve stent used safely comprising a supporting net frame, and a flared section connected to an end of the supporting net frame; wherein the flared section is connected to all end nodes located at a corresponding side of the supporting net frame, the flared section is grid shaped, and a number of intersection points of the grids decreases along an axial direction away from the supporting net frame. The present invention also provides a valve replacement device comprising an above valve stent and a prosthesis valve fixed inside the supporting net frame.

Abstract: A radiation detection system and method for a neutron capture therapy system, which may increase the accuracy of neutron beam irradiation dose of the neutron capture therapy system and find out a fault position in time. The neutron capture therapy system includes a charged particle beam, a charged particle beam inlet allowing the charged particle beam to pass through, a neutron beam generating unit which may generate a neutron beam after a nuclear reaction occurs between the neutron beam generating unit and the charged particle beam, a beam shaping assembly for adjusting the flux and the quality of the neutron beam generated by the neutron beam generating unit, and a beam outlet adjacent to the beam shaping assembly, the radiation detection system includes a radiation detection device for real-time detection of ? rays instantly emitted under neutron beam irradiation.

Abstract: The present invention provides a method of treating or alleviating erectile dysfunction in a patient. Multiple electrodes are placed within a segment of the internal iliac artery of the patient and against blood vessel wall of the internal iliac artery. Radiofrequency energy is released through at least one of the multiple electrodes to nearby tissues, so as to increase the temperature of the nearby tissues and induce a thermal alteration of the nearby tissues.

Abstract: A surgical instrument for thermally-mediated therapies in targeted tissue volumes and for causing thermal effects in polymer tissue-contacting members. In one embodiment, the instrument has a working end with an interior chamber that is supplied with a biocompatible liquid. An energy source causes a liquid-to-vapor phase change within the interior of the instrument. The vapor phase media then is ejected from the working surface of the instrument, and a controlled vapor-to-liquid phase change in an interface with tissue applies thermal energy substantially equal to the heat of vaporization to ablate tissue. The vapor-to-liquid phase transitions, or internal energy releases, can be provided about thin-film flexible structures for engaging body lumens and cavities. An exemplary embodiment can be used for shrinking, sealing, welding or creating lesions in tissue—while causing limited collateral thermal damage and while totally eliminating electrical current flow in the engaged tissue.

Abstract: A single use injector is a disposable injection device that is specifically optimized for production using the blow fill seal (BFS) manufacturing process and includes various mechanisms that render the device inoperable and facilitate its safe disposal after use. The single use injector incorporates an ampoule aseptically filled with a medication that is coupled to a hermetically sealed component system. The hermetically sealed component system incorporates various mechanisms that are actuated during the use of the injection device. The injection device is encased in a removable overtube that prevents contamination. upon removal of the overtube, the injection device is activated, by compression of a needle cap that irreversible punctures the ampoule in order to inject the medication through a needle. The injection device additionally incorporates a shield that deploys over the needle following injection of the medication into a patient.

Abstract: The present invention provides an anti-fracture sheath. The anti-fracture sheath comprises a tube body and an expansion section for accommodating an implantable device, wherein one side of the distal end of the tube body is joined with the expansion section, at least two reinforcing ribs are axially arranged on the tube wall of the expansion section in an internally extending manner, and the proximal ends of the reinforcing ribs extend from the expansion section and are fixedly connected with the tube wall of the tube body; and the materials of the reinforcing ribs are Kevlar fibers, the diameter of each reinforcing rib is from 0.03 mm to 0.12 mm, and the number of the reinforcing ribs is from two to four. The anti-fracture sheath provided by the present invention has the advantage that the strength of the expansion section is improved when the whole compliance of the sheath is maintained, thereby avoiding fracture of the sheath in an implantable device releasing process.

Abstract: A medical path navigation method, planning method and device are provided. The navigation method includes: planning a navigation path; delivering an ablation catheter with a localization sensor into an airway leading to a lesion region according to the navigation path; adjusting a position and a direction of the ablation catheter in the airway based on the localization sensor during a moving process of the ablation catheter in the airway until the ablation catheter is navigated to a planned initial ablation region; and adjusting a position and a direction of the ablation catheter in the lesion region based on the localization sensor during a moving process of the ablation catheter in the lesion region until the ablation catheter is navigated to other ablation regions, thereby accurately navigating the ablation catheter to a lesion position that is not reachable by a bronchoscope.