Patents Assigned to Mitsui Toatsu Chemicals, Incorporated
  • Process for producing p-hydroxyneophyl m-phenoxybenzyl ether
    Patent number: 5144083
    Abstract: A process for producing a p-hydroxyneophyl m-phenoxybenzyl ether represented by the general formula (II) ##STR1## (X.sub.1 and X.sub.2 are independently a hydrogen atom or a halogen atom) by subjecting a corresponding p-alkoxyneophyl m-phenoxybenzyl ether represented by the general formula (I) ##STR2## (R represents a lower alkyl group, and X.sub.1 and X.sub.2 have the same definitions as above) to ether cleavage, in which process the ether cleavage reaction is effected in an aprotic polar solvent, using a lower alkoxide of an alkali metal or an alkaline earth metal or using a metal hydroxide in the presence of a lower alcohol.
    Type: Grant
    Filed: October 2, 1990
    Date of Patent: September 1, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Hideyuki Akieda, Naoki Sato, Koichi Morinaga, Yoshinori Ide, Ryuichi Mita, Mitsumasa Umemoto
  • Method for preparing acrolein or methacrolein
    Patent number: 5144090
    Abstract: A method for preparing acrolein or methacrolein comprises subjecting propylene, secondary propanol, isobutylene or tertiary butanol to gas phase catalytic oxidation with molecular oxygen in the presence of a catalyst represented by the following general formula (I):Mo.sub.a Bi.sub.b Fe.sub.c X.sub.d Y.sub.O Z.sub.f O.sub.g (I)wherein X represents at least one element selected from the group consisting of Ni and Co; Y represents at least one element selected from the group consisting of K, Rb, Cs and Tl; and Z represents at least one element selected from the group consisting of Be, Mg, Ca, Sr, Ba, Ce, Ti, Zr, Nb, Cr, W, Mn, Cu, Ag, Zn, Cd, B, Al, Si, Ge, Sn, Pb, P, As, Sb, S, Se and Te; a, b, c, d, e, f and g each represents an atomic ratio of the corresponding element and when a is assumed to be 12, b=0.1.about.10, c=0.1.about.20, d=2.about.20, e=0.01.about.2, f=0.about.
    Type: Grant
    Filed: June 6, 1991
    Date of Patent: September 1, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Tadatoshi Honda, Tokio Nagayama, Nobuhiko Horiuchi, Jun Kitagawa, Kazunori Kawahara, Masami Murakami
  • Purification procedure of TPA from crude preparations
    Patent number: 5141863
    Abstract: Tissue plasminogen activator (tPA) species having a specific molecular weight can be isolated in a purified form from a crude tPA preparation containing various tPA species having different molecular weights by bringing the crude tPA preparation into contact with hydroxyapatite and then separately eluting the adsorbed tPA species with eluents having different pHs and/or salt concentrations.
    Type: Grant
    Filed: May 1, 1990
    Date of Patent: August 25, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Katsuyuki Suzuki, Nobuhiro Kawashima, Noriko Morii, Kunizou Mori
  • Production method of goethite
    Patent number: 5139767
    Abstract: A method for producing goethite having an axial ratio of at least 7 and a specific surface area of 20-80 m.sup.2 /g and suitable for use in the production of .alpha.-iron powder, which method comprises intermittently feeding an oxidizing gas into a suspension of ferrous hydroxide, which has been obtained by reacting a ferrous salt with an alkali hydroxide, preferably while controlling the oxidation rate of ferrous hydroxide below 7% per each feeding-feed-stopping cycle of the oxidizing gas and also controlling the feeding time period of the oxidizing gas within 10 minutes and shorter than a quarter of the feed-stopping time period per each feeding-feed-stopping cycle of the oxidizing gas.
    Type: Grant
    Filed: January 4, 1991
    Date of Patent: August 18, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Mitsurou Matsunaga, Isamu Morita, Nobuhiro Fukuda
  • Method of regulating expression of a foreign gene by controlling the sugar concentration in a medium and a process of producing a foreign product thereby
    Patent number: 5139935
    Abstract: Escherichia coli carrying a hybrid plasmid having been constructed by inserting a desired foreign gene into an expression vector so as to permitting expression of said desired foreign gene therein was cultured in a medium containing a sugar component utilizable by the E. coli as a carbon source at a concentration of 0.3% or more so that the expression of said desired foreign gene was suppressed. This E. coli (i.e., transformant) was cultured in the medium in which the sugar concentration was maintained at 0.3% or more in a first process so as to supress the suppression of the foreign gene and to support sufficient cell growth and thereafter at less than 0.3% in a second process to release the suppression of the expression so as to permit effective production of the foreign gene product, which resulted in high concentration of the foreign gene product in the final culture.
    Type: Grant
    Filed: February 25, 1991
    Date of Patent: August 18, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Nobuhiro Fukuhara, Setsuo Yoshino, Satori Sone, Yoshiyuki Nakajima, Nobuyoshi Makiguchi
  • Stretched films of polyproplene
    Patent number: 5132157
    Abstract: A stretched film of polypropylene which is excellent in transparency, substantially free of an antiblocking agent and at least uniaxially stretched and which is characterized in that it has uniformly distributed projections having a height ranging from 0.05 to 0.50 .mu. and a width ranging from 10 to 100 .mu. at least on the surface thereof as well as a method for preparing the foregoing stretched film of polypropylene which comprises the steps of forming, into a sheet, polypropylene which comprises a nucleating agent in an amount selected so that the crystallization temperature of polypropylene is increased by 1.degree.to 10.degree. C. by the addition thereof and then stretching the sheet at a temperature ranging from 140.degree. to 165.degree. C. are herein disclosed.
    Type: Grant
    Filed: May 21, 1990
    Date of Patent: July 21, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Tadashi Asanuma, Kazuhiko Yamamoto, Tateyo Sasaki, Takeo Inoue, Takayuki Yamada
  • 4-ethyl-3-(substituted phenyl)-1-(3-trifluoromethylphenyl)-2-pyrrolidinone derivatives, herbicidal compositions containing them and use thereof
    Patent number: 5131947
    Abstract: 4-Ethyl-3-(phenyl)-1-(3-trifluoromethylphenyl)-2-pyrrolidinones and corresponding compounds bearing a p-substituent on the 1-position phenyl group and/or a substituent on the 3-position phenyl group exhibit selective herbicidal activities against various weeds which cause problems in rice or upland fields, even at extremely low application rates. They can be prepared by reductive dehalogenation of a corresponding .alpha.-haloethyl substituted pyrrolidinone or reductive cyclization of a corresponding N-2-butenyl-N-(substituted phenyl)-haloacetyl-3-trifluoromethylaniline.
    Type: Grant
    Filed: March 14, 1990
    Date of Patent: July 21, 1992
    Assignee: Mitsui Toatsu Chemicals Incorporated
    Inventors: Kengo Oda, Koichi Moriyasu, Kiyoshi Arai, Kanji Tomiya, Miura Tohru, Makoto Nishida, Masami Oyamada, Akie Fujiwara
  • Established cell line, KML.sub.1-7, which produces B-cell differentiation factor (BCDF)
    Patent number: 5132222
    Abstract: A novel established cell line, KML.sub.1-7, obtained by collecting lymphoid cells from an animal with autoimmune disease, culturing them in a culture medium containing the supernatant of a culture in which lymphoid cells of animal origin have been grown in the presence of a mitogen, and continuing the culture for a period of 8 months until the cells are able to grow in the absence of the aforesaid supernatant. This established cell line has the following properties.(1) It produces a factor, B-Cell Differentiation Factor (BCDF), participating in the differentiation of antibody-producing cells.(2) It does not produce B cell growth factor.(3) It consists of immortalized null cells.
    Type: Grant
    Filed: November 27, 1991
    Date of Patent: July 21, 1992
    Assignee: Mitsui Toatsu Chemicals Incorporated
    Inventors: Yoshiyuki Kanai, Akira Awaya
  • Hydrozones and electrophotographic photoreceptors comprising them
    Patent number: 5132190
    Abstract: A hydrazone compound represented by the following formula (I): ##STR1## wherein R.sub.1 and R.sub.2 each are an aryl group or collectively with the carbon to which they are attached form a polycyclic group; R.sub.3 represents a hydrogen or halogen atom or an alkyl or phenyl group; and R.sub.4 and R.sub.5 each represent an alkyl, aralkyl or aryl group, with the proviso that at least one of R.sub.4 and R.sub.5 is an aryl group, is useful as a charge-transporting material in an electrophotographic photoreceptor and are produced by condensing the corresponding aldehyde with the corresponding H.sub.2 N--NR.sub.4 R.sub.5 hydrazine.
    Type: Grant
    Filed: April 9, 1990
    Date of Patent: July 21, 1992
    Assignee: Mitsui Toatsu Chemicals Incorporated
    Inventors: Yasuyuki Yamada, Hiroyuki Akahori, Katashi Enomoto, Hisato Itoh, Tsutomu Nishizawa, Akihiro Yamaguchi
  • Pyridyloxypyrimidine derivatives, preparation process thereof, and herbicidal compositions containing the same as active ingredients
    Patent number: 5129937
    Abstract: Herbicidally active pyridyloxypyrimidines represented by the following formula [I]: ##STR1## wherein R means a formyl group or an acetal group represented by ##STR2## R.sup.1 and R.sup.2 being the same or different and individually denoting an alkyl group having 1-4 carbon atoms or R.sup.1 and R.sup.2 being coupled together and denoting an alkylene group, R.sup.3, having 2-3 carbon atoms; are prepared by reacting 2 formyl-3-hydroxypyridine or 3-hydroxy-2-pyridine carboxaldehyde acetal with 2 halogeno-4,6 dimethoxypyrimidine in the presence of a base.
    Type: Grant
    Filed: December 21, 1990
    Date of Patent: July 14, 1992
    Assignee: Mitsui Toatsu Chemicals Incorporated
    Inventors: Tsutomu Ishii, Katsutoshi Ishikawa, Masatoshi Gohbara, Yasunaga Iwasaki, Makoto Nishida
  • Alicyclic diamines, alicyclic diisocyanates and polyisocyanato-isocyanurates and method for the preparation thereof
    Patent number: 5126426
    Abstract: Herein disclosed are an .alpha.-(aminocyclohexyl)alkylamine represented by the following general formula (II): ##STR1## wherein R represents hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms, provided that the amino group bonded to the cyclohexyl group may be in either of the 2-, 3- and 4-positions and a method for preparing it; an .alpha.-(isocyanatocyclohexyl)alkylisocyanate of Formula (II) wherein the amino groups are replaced with isocyanato groups and a method for preparing it; polyisocyanato-isocyanurate represented by the following general formula (IV): ##STR2## wherein R.sub.1, R.sub.2 and R.sub.
    Type: Grant
    Filed: April 19, 1990
    Date of Patent: June 30, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Ryuji Haseyama, Masatoshi Takagi, Kouzou Hayashi, Katsuyoshi Sasagawa, Kazuyuki Kuroda, Taisaku Kano, Kiyoshi Shikai
  • Near infrared absorbers and display/recording materials using the same
    Patent number: 5124067
    Abstract: Near infrared absorbers which have a molecular extinction coefficient of 200,000 or more and are represented by the formula (I) ##STR1## wherein each of Y.sup.1, Y.sup.2, Y.sup.3, Y.sup.4, Y.sup.5, Y.sup.6, Y.sup.7 and Y.sup.8 is hydrogen, an alkyl group, alkoxyl group or alkylthio group; each of A.sup.1, A.sup.2, A.sup.3, A.sup.4, A.sup.5, A.sup.6, A.sup.7 and A.sup.8 is hydrogen, halogen, a nitro group, alkyl group, aralkyl group, alkenyl group, alkynyl group, alkoxyl group, aryloxy group, alkylthio group or arylthio group; and Met represents two hydrogen atoms or a metal, are useful for the production of optical display and recording materials.
    Type: Grant
    Filed: December 15, 1989
    Date of Patent: June 23, 1992
    Assignees: Mitsui Toatsu Chemicals, Incorporated, Yamamoto Chemicals, Incorporated
    Inventors: Hisao Itoh, Katashi Enomoto, Takahisa Oguchi, Tutomu Nishizawa
  • 3,4-trans-4-ethyl-1-(substituted phenyl)-3- (substituted phenyl) pyrrolidin-2-ones, method for preparing the same, and herbicidal method compositions containing the same as herbicidally active ingredients
    Patent number: 5123954
    Abstract: A 3,4-cis isomer of 4-ethyl-1-(substituted phenyl)-3-substituted phenyl)pyrrolidin-2-one, when reacted with a base, can be effectively convered into a 3,4-trans isomer thereof which has a high herbicidal activity useful as an effective ingredient for a herbicidal composition. Furthermore, 3,4-trans-4-ethyl-1-(substituted phenyl)-3-(substituted phenyl)pyrrolidin-2-one compounds represented by the formula (III) ##STR1## (wherein R.sup.2 is an isopropyl group, and X is a fluorine atom, chlorine atom or bromine atom substituted at the 3-position, or fluorine atoms substituted at the 3- and 4-positions or the 3- and 5-positions) have an extremely excellent activity particularly as a herbicidally active ingredient of the herbicidal composition for rice paddy fields.
    Type: Grant
    Filed: September 6, 1991
    Date of Patent: June 23, 1992
    Assignee: Mitsui Toatsu Chemicals Incorporated
    Inventors: Koichi Moriyasu, Kengo Oda, Kanji Tomiya, Tohru Miura, Makoto Nishida, Sachiko Hibi
  • Process for the removal of chloroprene from, 1,2-dichloroethane
    Patent number: 5122235
    Abstract: Disclosed herein is a process for removing chloroprene by subjecting chloroprene-containing 1,2-dichloroethane to heat treatment at a temperature in the range of from the boiling point (85.degree. C.) of 1,2-dichloroethane to the thermal cracking temperature (300.degree. C.) of 1,2-dichloroethane. In particular, the process can be suitably applied to a liquid distillate from a low-boiling material separation column in a step in which 1,2-dichloroethane used as a raw material for production of vinyl chloride is purified by using a fractionation column.
    Type: Grant
    Filed: August 10, 1990
    Date of Patent: June 16, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Kenji Shirai, Seiji Nagae, Tadashi Naito, Atsushi Shirai
  • Benzoquinone dye, rope-dyeing dye compositions, cotton rope-dyeing methods using same, and the thus dyed materials
    Patent number: 5122160
    Abstract: Denim cotton warp yarns are rope-dyed with a benzoquinone dye of formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.1 ', R.sub.2 ' and R.sub.3 ' commonly or independently represent a hydrogen atom, a halogen atom, alkyl, cycloalkyl, alkenyl, aryl, aralkyl, alkoxyl or alkoxyalkyl alone or in combination with a red .DELTA..sup.2,3' -biindolin-3,2'-dione dye and/or a blue indigoid dye or sequentially with the latter dye.
    Type: Grant
    Filed: December 4, 1990
    Date of Patent: June 16, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Hitoshi Koshida, Tetsuo Sakagawa, Takayuki Nakayama, Hiroshi Suwa, Akitoshi Igata, Masao Imai
  • Dihydrocaffeic acid derivatives and pharmaceutical preparations containing same
    Patent number: 5116979
    Abstract: Dihydrocaffeic acid derivatives are here disclosed which are applicable as medicines having excellent absorbency in the case of oral administration and good concentration retention in blood.The disclosed compounds have the function to induce the production and secretion of a nerve growth factor (NGF) in the brain tissue, and therefore they are effective as medicines for the progression inhibition and therapy of regressive disorders of the central nervous system.
    Type: Grant
    Filed: September 6, 1990
    Date of Patent: May 26, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Nobuyuki Fukazawa, Hajime Iizuka, Osamu Yano, Yukio Miyama
  • Pyrimidinedione derivative compounds, method for preparing same, and antiarrythmic agents containing same
    Patent number: 5114941
    Abstract: A pyrimidinedione derivative compound has a basic backbone in which a 4-oxobenzopyran ring group part and a pyrimidinedione part are linked by a structure comprising an alkyl chain containing at least two nitrogen atoms and one oxygen. The pyrimidinedione derivative is useful for a medical treatment of cardiac arrhythmias.
    Type: Grant
    Filed: November 27, 1990
    Date of Patent: May 19, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Tsutomu Katakami, Tatsuro Yokoyama, Haruki Mori, Nobuya Kawauchi, Joji Kamiya, Masaaki Ishii
  • Thermosetting resin composition
    Patent number: 5112899
    Abstract: A thermosetting resin composition formed of a polyaminobismaleimide resin, which is composed of a bismaleimide compound and a diamine compound, and a fibrous reinforcing material. The composition has excellent impact resistance and toughness while retaining conventional high heat resistance.
    Type: Grant
    Filed: September 18, 1990
    Date of Patent: May 12, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Norimasa Yamaya, Masahiro Ohta, Akihiro Yamaguchi
  • Imidazole derivatives and antiepileptics comprising said imidazole derivatives as effective ingredients
    Patent number: 5112841
    Abstract: Described herein are imidazole derivatives having a specific structure and satisfactory as antiepileptics from the standpoint of the strength of action, prolonged action and side effects as well as their preparation processes.
    Type: Grant
    Filed: February 28, 1991
    Date of Patent: May 12, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Akira Matsubara, Kazuya Sakai, Hideki Tanada, Akira Mizuchi, Kazutoshi Horikomi, Takuma Ohtsu
  • Quinoline derivatives
    Patent number: 5112817
    Abstract: Novel heterocyclic compounds, which are represented by the following general formula, useful as anticancer drug potentiaters having a potentiating effect on the incorporation of anticancer drugs into cancer cells, the compounds each synthesized by, for example, reacting a epoxy compound obtained by reacting a heterocyclic compound with an epihalogenohydrin, with an amine derivative.
    Type: Grant
    Filed: October 6, 1992
    Date of Patent: May 12, 1992
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Nobuyuki Fukazawa, Makoto Odate, Tsuneji Suzuki, Kengo Otsuka, Takashi Tsuruo, Wakao Sato