Patents Assigned to Monash University
  • DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF
    Publication number: 20120046244
    Abstract: Disclosed herein are ionic liquid compositions comprising active pharmaceutical, biological, and nutritional compounds, and methods of use. Further disclosed are compositions of matter including liquid ion pairs alone or in solution and their use; compositions of ionic liquids that are ‘solvated,’ for example, ‘hydrated’ and their uses.
    Type: Application
    Filed: December 29, 2009
    Publication date: February 23, 2012
    Applicants: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA, QUEEN'S UNIVERSITY BELFAST, MONASH UNIVERSITY
    Inventors: Robin D. Rogers, Daniel T. Daly, Douglas MacFarlane, Janet L. Scott, Kenneth R. Seddon, Gabriela Gurau, Katharina Bica, Jelena Turanjanin, Pamela M. Dean
  • METHOD OF FABRICATING MICROFLUIDIC SYSTEMS
    Publication number: 20120009662
    Abstract: A method of fabricating a microfluidic system having microfluidic channels on a surface of a hydrophilic substrate, the method including the steps of: hydrophobizing the substrate surface; locating a mask defining the substrate surface, the mask having open areas defining the periphery of the microfluidic channels; and applying an irradiation treatment to areas of the substrate surface exposed by the open areas of the mask, said exposed areas becoming hydrophilic to therefore form said microfluidic channels.
    Type: Application
    Filed: July 10, 2009
    Publication date: January 12, 2012
    Applicant: Monash University
    Inventors: Wei Shen, Xu Li, Junfei Tian, Mohidus Samad Khan, Gil Garnier
  • PHOTOVOLTAIC DEVICES
    Publication number: 20110303271
    Abstract: A photovoltaic device including cathode and anode electrodes (3, 11), and a photovoltaically active layer (5) located over both said electrodes.
    Type: Application
    Filed: November 27, 2009
    Publication date: December 15, 2011
    Applicant: MONASH UNIVERSITY
    Inventors: Udo Bach, Dongchuan Fu
  • DIAGNOSTIC AND THERAPEUTIC PROTOCOLS
    Publication number: 20110230571
    Abstract: The present invention relates to methods for determining co-receptor usage of an HIV in a subject including the steps of: culturing a viral preparation derived from the subject's plasma with one or more cell lines which express surface CD4 and CCR5, surface CD4 and CXCR4, or surface CD4, CCR5 and CXCR4, wherein an anticoagulant is added to the viral preparation or to the culture; and screening for infection, wherein the presence or absence of infected cells is indicative of the co-receptors used by the HIV.
    Type: Application
    Filed: October 24, 2008
    Publication date: September 22, 2011
    Applicants: ALFRED HEALTH, MONASH UNIVERSITY
    Inventors: Sharon R. Lewin, Alyssa Marie Cornall, Paul Urquhart Cameron
  • METHOD AND DEVICE FOR PHASE MEASUREMENT
    Publication number: 20110194120
    Abstract: The present invention relates to the field of phase measurement, particularly optical phase measurement. In one form, the invention relates to a method and device for measuring the phase between distinct signals by converting phase variations between the signals into amplitude variations. In one embodiment the invention provides a method of arranging the structure of a two-dimensional or three-dimensional crystal to measure the phase between signals, comprising the steps of (i) providing a respective waveguide for each signal and (ii) providing a micro-cavity array arranged to provide a resonance output in response to the phase of the signals. The invention has application to a wide range of apparatus and devices across many industries including communications, food technology, pharmacology, medicine and biology.
    Type: Application
    Filed: May 21, 2009
    Publication date: August 11, 2011
    Applicants: MONASH UNIVERSITY, THE AUSTRALIAN NATIONAL UNIVERSITY
    Inventors: Vajira Samapth AMARATUNGA, Haroldo Takashi Hattori, Malin Premaratne, Hark Hoe Tan, Chennupati Jagadish
  • METHODS OF TREATING THROMBOEMBOLIC DISORDERS
    Publication number: 20110190270
    Abstract: The field of the invention relates to methods for dissolving a thrombus using inhibitors of platelet contractility. More particularly, the present invention relates to the use of an inhibitor of platelet contractility in combination with one or more thrombolytic agents and optionally one or more anticoagulants for inhibiting platelet contraction and consolidation in the developing thrombus.
    Type: Application
    Filed: January 30, 2009
    Publication date: August 4, 2011
    Applicant: MONASH UNIVERSITY
    Inventors: Shaun Jackson, Simone Schoenwaelder, Akiko Ono
  • PIEZOELECTRIC ACTUATOR FOR USE IN MICRO ENGINEERING APPLICATIONS
    Publication number: 20110148253
    Abstract: A piezoelectric actuator including a piezoelectric element and an elongate transducer mounted on the piezoelectric element. The transducer is formed from an elongate cylindrical member, and at least one helical slot is provided around the outer surface of the cylindrical member to enable coupling of resonance modes of the transducer when actuated by the piezoelectric element.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 23, 2011
    Applicant: MONASH UNIVERSITY
    Inventors: James Robert Friend, Leslie Yu-Ming Yeo, Brett Watson
  • Polyol Based - Bioceramic Composites
    Publication number: 20110142790
    Abstract: Polyol-bioceramic composites are prepared by the reaction of a polyol and polycarboxylic acid in the presence of a bioceramic. Implantable medical devices fabricated at least in part with the crosslinked polyol-bioceramic composite materials are useful in a wide variety of applications.
    Type: Application
    Filed: November 23, 2010
    Publication date: June 16, 2011
    Applicant: Monash University
    Inventor: Qizhi Chen
  • Antibody against a human ADAM protease
    Patent number: 7960513
    Abstract: Elucidation of the crystal structure of an ADAM10 substrate-recognition and proteinase-positioning module comprising the protein cysteine-rich and disintegrin domains, and detailed functional analysis revealed that an acidic pocket within the cysteine-rich domain forms a substrate-recognition site. The binding of this pocket to receptor/ligand complexes facilitates effective ligand cleavage, which is prevented when critical residues within the pocket are changed. This provides use of the surface pocket within the extracellular domain of ADAM10, and the corresponding structure in related proteases such as ADAM17, as a target for structure-based computational and high-throughput screens for small-molecule substrate-specific inhibitors or monoclonal antibodies that inhibit ADAM protease cleavage of ephrins and other ADAM10 or ADAM17 substrates.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: June 14, 2011
    Assignees: Monash University, Memorial Sloan Kettering Cancer Center
    Inventors: Martin Lackmann, Peter W. Janes, Dimitar B. Nikolov, Nayanendu Saha
  • ELECTRODE FOR ELECTROCHEMICAL CELLS
    Publication number: 20110117454
    Abstract: The invention relates to an electrode for oxygen reduction comprising a porous organic material and at least one inherently conducting polymer such as a charge transfer complex or a conductive polymer, optionally combined with a non-conducting polymer. A current conductor may be located intermediate the porous organic material and the inherently conductive polymer. The electrode is suitable for use with an ion-conducting membrane and fuel such as hydrogen, an alcohol or borohydride to form a fuel-cell. The electrode is also suitable for use with an anode, such as a reactive metal and an electrolyte to form a battery.
    Type: Application
    Filed: February 6, 2009
    Publication date: May 19, 2011
    Applicant: Monash University
    Inventors: Bjorn Winther-Jensen, Maria Forsyth, Douglas Robert Macfarlane
  • ECTOPIC PREGNANCY TREATMENT
    Publication number: 20110110933
    Abstract: The invention pertains to methods for treating ectopic pregnancy. More particularly, the present invention relates to methods for treating unruptured ectopic pregnancy using a non-surgical method comprising the administration of an EGFR inhibitor alone or in combination with an anti-metabolite e.g. methotrexate (MTX). The methodology is potentially applicable to treatment of unruptured ectopic pregnancies of all sizes.
    Type: Application
    Filed: October 1, 2010
    Publication date: May 12, 2011
    Applicant: Monash University
    Inventors: STEPHEN TONG, Ulrika W. Nilsson, Terence Grant Johns
  • NOVEL BISMUTH(III) NSAID COMPOUNDS AND METHODS FOR THEIR USE
    Publication number: 20110086911
    Abstract: The present invention relates to the field of non-specific anti inflammatory drugs (NSAIDs). In particular, the invention relates to bismuth(III) tris-carboxylate complexes having the formula [Bi(III)L3]n including its pharmaceutically acceptable salts and solvates, wherein, L is chosen from the group comprising carboxylato-NSAIDs, their derivatives, prodrugs or metabolytes, and n is ?1. The bismuth(III) tris-carboxylate complexes of the invention may be formulated for use in treatments for a wide range of ailments, particularly those where an anti-microbial activity is advantageous. In a particularly preferred embodiment the bismuth(III) tris-carboxylate complexes of the present invention exhibit activity against bacteria found in the gastrointestinal tract such as Helicobacter pylori, Escherichia coli, Klebsiella pneumoniae, Bacillus pumilus, Staphylococcus aureus and Staphylococcus epidermidis.
    Type: Application
    Filed: October 13, 2009
    Publication date: April 14, 2011
    Applicant: Monash University
    Inventors: Philip Craig ANDREWS, Peter Courtney JUNK, Ish KUMAR, Richard L. FERRERO
  • ELECTROCHEMICAL NANOCOMPOSITE BIOSENSOR SYSTEM
    Publication number: 20110042225
    Abstract: The present invention relates to an electrode useful in electrochemical nanobiosensors for determining the presence or concentration of analytes in aqueous samples. In particular, the electrode comprises a biocatalyst or other bioreceptor entrapped in a conducting polymeric film deposited on a conducting material and a non-conducting or conducting coating. In particular embodiments, the conducting polymeric layer also comprises metallic nanoparticles. Electrochemical nanobiosensors containing the electrode, methods of making the electrode or sensor and methods of detecting analytes are other aspects of the invention.
    Type: Application
    Filed: December 12, 2008
    Publication date: February 24, 2011
    Applicant: MONASH UNIVERSITY
    Inventor: Samuel Bodunrin Olufemi Adeloju
  • IMMUNOSTIMULATORY siRNA MOLECULES
    Publication number: 20110039915
    Abstract: The present invention relates to a double-stranded siRNA molecule that is capable of silencing gene expression as well as inducing an immune response. The molecule comprises a sense strand and an antisense strand, wherein the antisense strand comprises a first nucleotide sequence that is specifically complementary to mRNA transcribed from a target gene, and the sense strand comprises a second nucleotide sequence that is substantially or perfectly complementary to the antisense strand with the exception that the second nucleotide sequence comprises at least one immunostimulatory motif comprising two or more non-complementary nucleotides. Such a molecule may be utilized in a method of treating or preventing a disease or condition (such as a viral infection, a bacterial infection, or cancer) in a subject.
    Type: Application
    Filed: February 16, 2009
    Publication date: February 17, 2011
    Applicant: MONASH UNIVERSITY
    Inventors: Michael Paul Marie Gantier, Stephen Tong, Bryan Raymond George Williams
  • Controlled Polymerisation Process
    Publication number: 20100331521
    Abstract: The present invention relates to a controlled metathesis-driven polymerisation process which is particularly useful for the synthesis of biological polymers such as peptides and polymers. The invention also provides metathesisable supports, groups and linkers for use in the process.
    Type: Application
    Filed: July 18, 2008
    Publication date: December 30, 2010
    Applicant: MONASH UNIVERSITY
    Inventors: Andrea Robinson, Rebecca Dee
  • Estimation of wheel rail interaction forces
    Patent number: 7853412
    Abstract: A method of estimating contact forces between the wheels of a railway wagon and a rail track, for use in determining information such as the likelihood of derailment. Accelerations of the body of the wagon are measured using motion sensors located at suitable points on the body. Forces on the side frames of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. Forces on the wheels of the wagon are calculated based on the accelerations of the body and predetermined parameters of the body. The contact forces between the wheels and the rails are then calculated based on the forces calculated for the side frames and the wheels. The calculations are carried out using an inverse model of the wagon system. Equipment which implements the method is also described.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: December 14, 2010
    Assignees: QR Limited, Australian Rail Track Corporation Ltd, Pacific National (Victoria) Ltd, Asciano Services Pty Ltd, TMG Rail Technology Pty Ltd, Rail Corporation NSW, Central Queensland University, University of Wollongong, Monash University, University of South Australia, Queensland University of Technology, The University of Queensland
    Inventors: Fujie Xia, Peter Joseph Wolfs
  • TREATMENT OF RAILWAY WHEELS
    Publication number: 20100276955
    Abstract: A method of treating a steel railway wheels to form a required distribution of compressive residual stress in the rim. In general terms the wheel heated and then quenched from the plate towards the rim. The wheel is first heated to form austenite throughout the plate and rim portions. The wheel is then cooled to form bainite/martensite in the plate portion. The wheel is cooled to form bainite/martensite in an inner portion of the rim. The wheel is cooled to form bainite/martensite in an outer portion of the rim.
    Type: Application
    Filed: June 19, 2008
    Publication date: November 4, 2010
    Applicants: QR LIMITED, AUSTRALIAN RAIL TRACK COPORATION LTD, PACIFIC NATIONAL (VICTORIA) LTD, ASCIANO SERVICES PTY LTD, TMG RAIL TECHNOLOGY PTY LTD, RAIL CORPORATION NSW, CENTRAL QUEENSLAND UNIVERSITY, UNIVERSITY OF WOLLONGONG, MONASH UNIVERSITY, UNIVERSITY OF SOUTH AUSTRALIA, QUEENSLAND UNIVERSITY OF TECHNOLOGY, THE UNIVERSITY OF QUEENSLAND
    Inventors: Bernard Chen, Timothy Robert Constable, Hung Nien Kha
  • SPEECH ANALYSIS SYSTEM
    Publication number: 20100274554
    Abstract: A speech analysis system, including a kurtosis module for processing a coded sound signal to generate kurtosis measure data; a wavelet module for processing the coded sound signal to generate wavelet coefficients; and a classification module for processing the wavelet coefficients and the kurtosis measure data to generate label data representing a classification for the coded sound signal. The sound signal is classified as environmental noise, silence, speech from a single speaker, speech from multiple speakers, speech from a single speaker plus environmental noise, or speech from multiple speakers plus environmental noise. Speech is further classified as voiced or unvoiced.
    Type: Application
    Filed: June 23, 2006
    Publication date: October 28, 2010
    Applicant: MONASH UNIVERSITY
    Inventors: Michael Christopher Orr, Brian John Lithgow
  • TREATMENT OF CHRONIC LUNG DISEASE
    Publication number: 20100266552
    Abstract: A method of cellular therapy for a lung disease or condition in a subject is disclosed, wherein the method involves the administration of multipotent epithelial stem cells derived from amnion tissue (AECs). In a particular application, the method is used for the treatment of lung diseases and conditions such as chronic lung diseases including chronic obstructive pulmonary disease (COPD), acute lung conditions such as acute respiratory distress syndrome (ARDS), and ventilator associated lung injury (VALI).
    Type: Application
    Filed: May 28, 2008
    Publication date: October 21, 2010
    Applicant: MONASH UNIVERSITY
    Inventors: Graham Jenkin, Alan Osborne Trounson, Euan Morrison Wallace, Yuben Moodley, Ursula Manuelpillai, Sivakami Ilancheran
  • NEURAL RESPONSE SYSTEM
    Publication number: 20100261978
    Abstract: A neural response system, including a plurality of filters for each receiving and filtering a plurality of tilt response signals obtained from a person; a segmenter for segmenting the filtered response signals into time segments; and a neural event extractor for performing a neural event extraction process on each of the time segments to obtain and generate biomarker data representing a plurality of biomarkers for each segment.
    Type: Application
    Filed: May 30, 2008
    Publication date: October 14, 2010
    Applicant: MONASH UNIVERSITY
    Inventor: Brian John Lithgow