Patents Assigned to Monash University
  • Method and formulation for inhalation
    Publication number: 20140294969
    Abstract: This invention relates to drug delivery and in particular to the delivery of biologically active agents in the form of dry powders for inhalation. The invention also relates to methods for preparing such dry powder formulations and methods for their use.
    Type: Application
    Filed: November 7, 2011
    Publication date: October 2, 2014
    Applicant: Monash University
    Inventors: Michelle Mcintosh, David Morton, Tomas Sou, Livesey Olerile, Richard Prankerd
  • HEART IMAGING METHOD
    Publication number: 20140286556
    Abstract: The present invention relates to imaging of a human or animal heart, particularly imaging of movement of the heart and can be used for imaging function and form in a wide range of research, medical, veterinary and industrial applications. In particular, the present invention provides a method and apparatus for imaging a subject heart, the method including the steps of (1) recording at least one in vivo image of a lung of the subject in one or more regions; (2) applying said at least one in vivo image to a 2D or 3D heart model; and (3) reconstructing a 2D or 3D image field of the subject heart.
    Type: Application
    Filed: October 10, 2012
    Publication date: September 25, 2014
    Applicant: MONASH UNIVERSITY
    Inventors: Andreas Fouras, Stephen Dubsky, Jordan Thurgood
  • Affinity ligands and methods for protein purification
    Patent number: 8748582
    Abstract: The present invention relates generally to affinity ligands and chemical affinity ligand-matrix conjugates for use as chromatographic adsorbents and methods which utilize the adsorbents in the purification of proteins by affinity chromatography. The affinity ligand-matrix conjugates of the present invention comprise ligands of general formula (I): wherein m represents an integer from 0-2, n represents an integer from 0-6, p represents an integer from 0-4, R1 represents H or C1-3 alkyl, R2 is an optional substituent, and X is the position at which the ligand is immobilized, optionally via a linker.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: June 10, 2014
    Assignee: Monash University
    Inventors: Milton T W Hearn, Anjali Makarand Bhagwat, William Roy Jackson, Simon John Mountford
  • LITHIUM ENERGY STORAGE DEVICE
    Publication number: 20140125292
    Abstract: The present invention generally relates to lithium based energy storage devices. According to the present invention there is provided a lithium energy storage device comprising: at least one positive electrode; at least one negative electrode; and an ionic liquid electrolyte comprising an anion, a cation counterion and lithium mobile ions, wherein the anion comprises a nitrogen, boron, phosphorous, arsenic or carbon anionic group having at least one nitrile group coordinated to the nitrogen, boron, phosphorous, arsenic or carbon atom of the anionic group.
    Type: Application
    Filed: October 28, 2013
    Publication date: May 8, 2014
    Applicants: MONASH UNIVERSITY, COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Adam Samuel Best, George Hamilton Lane
  • BINDER POWDERS
    Publication number: 20140050795
    Abstract: The present disclosure relates generally to binder powders for use in powder material processing and processes for their preparation. The disclosure further relates to binder powders for use in making solid powder compact forms, solid powder compact forms containing said binder powders and methods for making solid powder compact forms.
    Type: Application
    Filed: February 28, 2012
    Publication date: February 20, 2014
    Applicant: Monash University
    Inventors: David Morton, Laurence Orlando, Tony Q. Zhou, Louise C. Ho
  • CATALYSTS AND METHODS OF USE
    Publication number: 20140034510
    Abstract: The present invention relates to a catalyst comprising (i) a semiconductor preferably comprising one or more metal-(Group VIb) semiconductors, and (ii) a semiconductor material having elevated phosphorous content preferably comprising one or more metal-(Group VIb))-phosphorous species
    Type: Application
    Filed: March 22, 2012
    Publication date: February 6, 2014
    Applicant: MONASH UNIVERSITY
    Inventors: Douglas Macfarlane, Bjorn Winther-Jensen, Alexey Izgorodin
  • EphA3 antibodies for the treatment of solid tumors
    Patent number: 8637016
    Abstract: The invention provides methods and compositions comprising anti-EphA3 antibodies for the treatment of solid tumors.
    Type: Grant
    Filed: March 10, 2008
    Date of Patent: January 28, 2014
    Assignees: KaloBios Pharmaceuticals, Inc., Monash University, Ludwig Institute for Cancer Research Limited
    Inventors: Martin Lackmann, Andrew Mark Scott, Christopher R. Bebbington, Geoffrey T. Yarranton, Carmelina Murone, Catherine To
  • Controlled polymerisation process
    Patent number: 8552133
    Abstract: The present invention relates to a controlled metathesis-driven polymerization process which is particularly useful for the synthesis of biological polymers such as peptides and polymers. The invention also provides metathesisable supports, groups and linkers for use in the process.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: October 8, 2013
    Assignees: Syngene Limited, Monash University
    Inventors: Andrea Robinson, Rebecca Dee Garland
  • IONIC LIQUIDS FOR BATTERIES
    Publication number: 20130202973
    Abstract: An organic cation for a battery, including a heteroatom-containing cyclic compound having at least (2) ring structures formed from rings that share at least one common atom, the cyclic compound having both a formal positive charge of at least +1 and a partial negative charge.
    Type: Application
    Filed: March 18, 2011
    Publication date: August 8, 2013
    Applicants: MONASH UNIVERSITY, COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: George Hamilton Lane, Adam Samuel Best, Anand I. Bhatt, Youssof Shekibi, Bronya R. Clare
  • DIAGNOSTIC AND PROGNOSTIC ASSAY FOR BREAST CANCER
    Publication number: 20130202577
    Abstract: The invention relates to the finding that T cell protein tyrosine phosphatase (TCPTP) has a tumour suppressor function. In one particular application, the invention provides a method of diagnosis and/or prognosis of cancer in a subject involving the assessment, in a suitable body sample, of any lack or reduction of TCPTP protein and/or Ptpn2 gene expression. The invention also provides a method of treating or preventing cancer in a subject involving administering to a subject an agent for modulating the activity of TCPTP.
    Type: Application
    Filed: February 3, 2011
    Publication date: August 8, 2013
    Applicant: MONASH UNIVERSITY
    Inventors: Tony Tiganis, Benjamin James Shields, Catriona Ann McLean, Robert Sutherland
  • MATERIAL AND APPLICATIONS THEREFOR
    Publication number: 20130180912
    Abstract: A gel film or an isolated gel film comprising sheets of graphene or chemically converted graphene at least partially separated by a dispersion medium, such as water, and arranged in a substantially planar manner to form an electrically conductive matrix.
    Type: Application
    Filed: April 6, 2011
    Publication date: July 18, 2013
    Applicant: MONASH UNIVERSITY
    Inventor: Dan Li
  • METHODS OF CRYSTALLISING PERFORIN
    Publication number: 20130137859
    Abstract: A method for isolating crystals of perforin including the step of: crystallising perforin from solution at pH 6.4 to 8.0 and 20±5° C.
    Type: Application
    Filed: May 17, 2011
    Publication date: May 30, 2013
    Applicant: MONASH UNIVERSITY
    Inventors: James C. Whisstock, Ruby H.P. Law, Joseph Albert Trapani, Ilia Voskoboinik
  • Crystals of human glutamic acid decarboxylase 65 (GAD65)
    Patent number: 8420371
    Abstract: A crystal comprising an isoform of an N-terminally truncated glutamic acid decarboxylase (GAD) chosen from the group consisting of a monoclinic P21 space group with unit cell dimensions of a =84.05±2.3 ?, b=62.74±2.3 ?, c=101.35±2.3 ? and ? =106.69° (GAD67) or an orthorhombic C2221 space group with unit cell dimensions of a=78.25±2.3 ?, b=99.05±2.3 ? and c=120.01±2.3 ?(GAD65).
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: April 16, 2013
    Assignee: Monash University
    Inventors: James Charles Whisstock, Ashley Maurice Buckle, Gustavo Fenalti, Ruby Hong Ping Law, Merrill Joy Rowley
  • PARTICAL IMAGE VELOCIMETRY SUITABLE FOR X-RAY PROJECTION IMAGING
    Publication number: 20130070062
    Abstract: A 2D or 3D velocity field is reconstructed from a cross-correlation analysis of image pairs of a sample, without first reconstructing images of the sample spatial structure. The method can be implemented via computer tomographic x-ray particle image velocimetry, using multiple projection angles, with phase contrast images forming dynamic speckle patterns. Estimated cross-correlations may be generated via convolution of a measured autocorrelation function with a velocity probability density function, and the velocity coefficients iteratively optimised to minimise the error between the estimated cross-correlations and the measured cross-correlations. The method may be applied to measure blood flow, and the motion of tissue and organs such as heart and lungs.
    Type: Application
    Filed: August 17, 2012
    Publication date: March 21, 2013
    Applicant: MONASH UNIVERSITY
    Inventors: Andreas FOURAS, Stephen DUBSKY
  • TESTING DEVICE FOR IDENTIFYING ANTIGENS AND ANTIBODIES IN BIOFLUIDS
    Publication number: 20120322086
    Abstract: A testing device for identifying an antigen or antibody within a biofluid sample including: a substrate having a hydrophilic surface thereon; the surface including a collection zone, and at least one detection zone extending therefrom; wherein the biofluid sample can be mixed with a specific antigen or antibody, and deposited on the collection zone and transferred by capillary action to the detection zone; the antigen or antibody in the biofluid sample reacting with an appropriate said antibody or antigen thereby resulting in a visual indication within the detection zone.
    Type: Application
    Filed: September 24, 2010
    Publication date: December 20, 2012
    Applicant: Monash University
    Inventors: Gil Garnier, Wei Shen, Mohidus Samad Khan, Xu Li, George Thouas
  • ANAESTHETIC FORMULATION
    Publication number: 20120316146
    Abstract: The present invention relates generally to the field of drug delivery systems for neuroactive steroid anaesthetic agents. More particularly, anaesthetic and sedative formulations are provided in the form of host/guest preparations comprising one or more neuroactive steroid anaesthetics and a cyclodextrin. Particular cyclodextrins contemplated include sulfoalkyl ether cyclodextrins and modified forms thereof.
    Type: Application
    Filed: January 19, 2011
    Publication date: December 13, 2012
    Applicants: MONASH UNIVERSITY, GOODCHILD INVESTMENTS PTY LTD.
    Inventors: Juliet Marguerite Goodchild, Colin Stanley Goodchild, Benjamin James Boyd
  • METHODS FOR REGULATING BLOOD GLUCOSE LEVELS
    Publication number: 20120309677
    Abstract: The invention relates to methods and compositions for reducing blood glucose levels in hyperglycaemic subjects. The methods and compositions may therefore be suitable for treating a disease or condition associated with hyperglycaemia such as, for example, obesity (particularly diet induced obesity (DIO)), weight gain, Type II diabetes mellitus, insulin sensitivity, impaired glucose tolerance and inflammation. In some embodiments, the methods comprise administering a melanocortin-5 receptor (MC5R) agonist to one or more skeletal muscle cells of the subject. Preferred MC5R agonists are those that specifically activate MC5R and/or enhance expression of MC5R, such as the melanocortin analogue, Ac-Nle-c[Asp-Pro-D-Nal(2?)-Arg-Trp-Lys]-NH2.
    Type: Application
    Filed: January 25, 2011
    Publication date: December 6, 2012
    Applicant: Monash University
    Inventors: Michael Alexander Cowley, Pablo Jose Enriori, Russell Deputy Brown, Iain James Clarke, Belinda Anne Henry, Maria Cecilia Garcia-Rudaz
  • ANTIMALARIAL AGENTS THAT ARE INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE
    Publication number: 20120302586
    Abstract: Inhibitors of parasitic dihydroorotate dehydrogenase enzyme (DHOD) are candidate therapeutics for treating malaria. Illustrative of such therapeutic agents include the compound: and a triazolopyrimidine class of compounds that conform to Formula IX: and their solvates, stereoisomers, tautomers and pharmaceutically acceptable salts.
    Type: Application
    Filed: September 28, 2010
    Publication date: November 29, 2012
    Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, MONASH UNIVERSITY, CLAYTON, GLAXOSMITHKLINE INVESTIGACION Y DESARROLLO, S.L, UNIVERSITY OF WASHINGTON, MEDICINES FOR MALARIA VENTURE
    Inventors: Pradipsinh K. Rathod, David Floyd, Jeremy Burrows, Alka Marwaha, Ramesh Gujjar, Jose Coteron-Lopez, Margaret Phillips, Susan A. Charman, David Matthews
  • NAVIGABLE SYSTEM FOR CATHETER BASED ENDOVASCULAR NEUROSURGERY
    Publication number: 20120289897
    Abstract: A navigable system for catheter based endovascular neurosurgery including: a micro-motor (3) including a piezoelectric actuator (5) mounted to a free end of a guidewire or micro-catheter (2), the piezoelectric actuator (5) including a piezoelectric element (7), and an elongate transducer (9) mounted on the piezoelectric element (7) and extending therefrom, the transducer (9) being formed from an asymmetric hollow member, and an end member (15) located at a free end of the transducer (9); wherein electrical excitation of the piezoelectric element (7) induces one or both orthogonal flexural and axial vibration modes within the transducer (9), the coupling of the induced vibration modes thereby resulting in rotation of the end member (15) with three degrees of freedom (DOF).
    Type: Application
    Filed: September 3, 2010
    Publication date: November 15, 2012
    Applicant: Monash University
    Inventors: James Friend, Leslie Yeo, Bernard Yan
  • Wearable visual sensor and transceiver apparatus
    Patent number: D696712
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: December 31, 2013
    Assignee: Monash University
    Inventors: Mark Clement Armstrong, Kieran James John, Nicola Charlotte Andrews, Jessica Marie Cassar