Abstract: Provided is methods for producing mixtures of antibodies from a single host cell clone, wherein, a nucleic acid sequence encoding a light chain and nucleic acid sequences encoding different heavy chains are expressed in a recombinant host cell. The recombinantly produced antibodies in the mixtures according to the invention suitably comprise identical light chains paired to different heavy chains capable of pairing to the light chain, thereby forming functional antigen-binding domains. Mixtures of the recombinantly produced antibodies are also provided by the invention. Such mixtures can be used in a variety of fields.

Abstract: Method for estimating radiation dose received by a tissue of interest during an imaging scan comprising: i, obtaining image data of a body region including the tissue of interest, ii. sub-dividing the image data into axial slices, comprising tissue axial slices and non-tissue axial slices, iii. determining a net amount of radiation dose emitted or received by each axial slice by combining scan parameters of each axial slice with pre-calculated amounts of radiation dose, iiii summing the net amounts of radiation dose of all the tissue axial slices to obtain a tissue dose.

Abstract: A programmable hair trimming system has a hair trimming device including a receiving element configured to receive an electromagnetic field and at least one source element having an electromagnetic field source. The hair cutting length of the hair trimming device is adjustable, and the at least one source element is external to the hair trimming device and arranged to be placed in a fixed relationship to the head of a person. The hair trimming system is arranged to detect, by an electromagnetic tracking system, the position of the hair trimming device in relation to the at least one source element. Further the hair trimming system relates this position to a previously generated hair length profile data regarding the desired hair trimming length at various positions. Based on the desired hair trimming length at the sensed position, the trimmer cutting length is automatically and dynamically adjusted.

Abstract: Systems and methods for managing applications in a hybrid cloud environment are provided. The methods include obtaining first parameter values based on information that relates to a first cloud service provider; obtaining second parameter values based on information that relates to a second cloud service provider; and using the first parameter values and the second parameter values to determine whether to recommend a redeployment of the first application from the first cloud service provider to the second cloud service provider.

Abstract: The present invention relates to device, system and method for verifying image-related information of a medical image.

Abstract: The invention relates to x-ray imaging technology as well as image post-processing. Particularly, the present invention relates to post-processing of perfusion image data acquired by an x-ray imaging apparatus by absolutely or relatively normalizing perfusion image data to allow a preferred comparison of the image data, both with regard to different acquisitions as well as different patients. To allow normalization of perfusion image data, it may be desirable to know the amount of contrast agent injected, which remains in a coronary. Subsequently, image parameters may be adapted or normalized based on the known amount of contrast agent within the coronary for normalization of perfusion image data. To obtain a precise amount of injected contrast agent, the injected volume of contrast agent flowing through a defined region or section of a vessel may be estimated. Said injected volume of contrast agent may thus be deduced from the estimation of the total volume flow at this location.

Abstract: A pitch tube includes a first tube part and a second tube part. The first tube part and the second tube part are detachably connected to each other.

Abstract: An air-guide member (100) for guiding an air flow (AF) is provided for in a food preparation chamber of a cooking device that uses air flow (AF) to prepare food ingredients. The air-guide member (100) includes a plurality of air-deflecting arms (101) arranged symmetrically and extending in a horizontal plane (P) between an inner part (IP) and an outer part (OP) of the air-guide member (100). The air guide member configuration allows for directing the air flow upwards and more evenly between the outer part and the inner part of the air-guide. The food ingredients can thus receive a flow of hot air having a more uniform air pressure distribution, which results in a more even cooking of the food ingredients.

Abstract: For serving the new different needs of high dynamic range image handling and conversion of images to a different dynamic range in decoding strategies the inventor invented image encoder (201) for encoding at least one high dynamic range image (HDR_ORIG) for at least one time instant, and at least one image (Im_LDR_out) of a second dynamic range which is different from the one of the high dynamic range image by at least a factor two for the same time instant, which is arranged to encode a matrix of pixel colors for at least one of those two images, comprising a specification unit (212) which comprises a color saturation modification apparatus (202) as claimed in claim 1, and a saturation specification unit (204) arranged to specify a saturation modification specification function specifying a color-dependent saturation transformation, as a set of gains (g) for each possible value of a maximal one of at least two color difference values (R?-Y?, B?-Y?) of a pixel color (Y?,Cb,Cr), which color difference values a

Abstract: A method for optimizing an X-ray imaging system during a mammographic examination. In order to provide an optimization of the X-ray imaging a breast is compressed between a support plate and a compression plate. A force-height curve is then acquired during the compression. An elasticity value of the breast is determined based on the force-height curve. A parameter of the X-ray imaging system is optimized based on the determined elasticity value.

Abstract: Ultrasound imaging devices, systems, and methods are provided. In one embodiment, a method of reducing ringdown artifacts in an ultrasound imaging system includes obtaining a plurality of frames of samples including tissue information and a ringdown component; determining a reference frame based on the plurality of frames to approximate the ringdown component; subtracting the reference frame from a current frame of the plurality of frames to produce a difference frame; selecting between the current frame and the difference frame to obtain a ringdown-reduced frame to represent the tissue information; and forming an ultrasound image from the ringdown-reduced frame. In one embodiment, an ultrasound image processing system including a processing unit configured to compute a difference frame based on a current frame and a reference frame; and select between the current frame and the difference frame to obtain a ringdown-reduced frame to represent the tissue information.

Abstract: A method and system for identifying an attachment of a personal care device (10). The method includes attaching an attachment (14) containing a memory (16) to a body portion (12) of a personal care device. The personal care device is powered up. Data is retrieved from the memory of the attachment. Information about the attachment attached to the personal care device is extracted from the retrieved data, the information including at least an association of the attachment to a specific user. An output characteristic of a status indicator (30) of the personal care device is associated with the ID (22) of the attachment. The status indicator is operated in accordance with the output characteristic when the attachment is coupled to the body portion of the personal device.

Abstract: A patient interface device is includes a cushion and a frame assembly coupled to the cushion, the frame assembly including a main frame member and a stiffening structure coupled to the main frame member, the stiffening structure having a main arm, a first Y-portion coupled to a first end of the main arm having first and second front branches extending at upward and downward angles, respectively, from the first end of the main arm, and a second Y-portion coupled to a second end of the main arm having first and second rear branches extending at upward and downward angles, respectively, from the second end of the main arm.

Abstract: A wheeled manure-removal vehicle for removing manure from an animal-shed floor includes a scraper assembly for scraping the manure together into a manure-storage space by scraping across the animal-shed floor. The scraper assembly includes a flexible, strip-shaped scraping element which is partly arranged around the manure-storage space and a rolling body. The rolling body extends on a side of the scraping element which faces away from the manure-storage space in order to be in contact with the scraping element at least while scraping the manure together, and has, on the side facing the scraping element, a rolling surface which is convexly rounded towards the scraping element. The use of the rolling body for contact with the scraping element has an advantageous effect on the life of the scraping element on the vehicle.

Abstract: A nozzle (12) for an oral irrigator device (10) having a guidance tip (34) with at least one orifice (36) at one end, and a nozzle spacer assembly (58) positioned around the at least one orifice (36). The at least one orifice is configured to expel a fluid as one of a jet, a spray, or any combination thereof. The nozzle spacer assembly (58) comprises at least two pairs of pliable spacers (60) that extend from the surface (35) for ensuring that the area at an entrance of an interproximal space between two teeth are treated, and (ii) establishing an improved angle of impact of the fluid expelled from the orifice.

Abstract: An oral cleaning device (10) configured to provide real-time feedback to a user. The oral cleaning device comprises a pressure sensor (12) configured to obtain pressure sensor data during a cleaning session; a visual indicator (46) configured to provide feedback about pressure to the user during the brushing session; and a controller (30) in communication with the pressure sensor and the visual indicator, wherein the controller is configured to: receive, from the pressure sensor, the pressure sensor data; determine an amount of pressure being applied by the user of the oral cleaning device; and provide, using the visual indicator, a visual indication of the amount of pressure being applied by the user of the oral cleaning device.

Abstract: A masticating juicer (10), including a housing (20) with a mastication chamber (30) and a food chute (40), the food chute defining a feeding chamber (50) positioned above the mastication chamber. The food processing apparatus further includes a food pusher (60) configured to be insertable into, and removable from, the feeding chamber. The food chute includes a flexible sealing member (80) that extends from the food chute into the feeding chamber. The flexible sealing member configured to engage the outer circumference of the food pusher when the food pusher is inside the feeding chamber, thereby preventing the back flow of food and juice through the food chute.

Abstract: The invention provides for a magnetic resonance imaging system (100) comprising a memory (134) for storing machine executable instructions (140) and pulse sequence commands (142). The pulse sequence commands are configured for controlling the magnetic resonance imaging system according to a DCE Magnetic Resonance Imaging protocol. The magnetic resonance imaging system further comprises a user interface (200) and a processor (130) for controlling the magnetic resonance imaging system.

Abstract: A treatment tool for reconditioning the top surfaces of a plurality of projections of a substrate support in a lithographic tool. The treatment tool includes a reconditioning surface which is rough relative to smoothed top surfaces of the projections and which reconditioning surface has material harder than that of the material of the top surfaces of the projections. A reconditioning method involves causing an interaction between the reconditioning surface of the treatment tool and the top surfaces of the projections of the substrate support, so as to leave these top surfaces rougher than they were prior to the interaction.

Abstract: According to an aspect, there is provided a fall detection apparatus for detecting a fall by a user, the fall detection apparatus comprising a processing unit configured to: receive measurements of movements of the user over time from a first movement sensor that is to be worn or carried by the user; determine if any of one or more objects are being carried or used by the user; and determine whether the user has fallen by processing the received measurements of the movements of the user and measurements of movements of any object that is being carried or used by the user.