Abstract: It discloses a chemical regeneration method of oxidized coenzyme NAD(P)+ which is under an oxygen or air atmosphere condition, adding a catalytic amount of bridged flavin, and oxidizing NAD(P)H to obtain NAD(P)+. The catalyst for regeneration of cofactor is cheap and easily available small organic molecule having no noble metal; this regeneration system can regenerate NADH and NADPH; this regeneration system has a wide pH range and temperature range, being applicable to various oxidation reactions catalyzed by nicotinamide-dependent oxidoreductase.
Abstract: A method to prepare functional polyester polyols by using micro-reaction device, wherein mixing ?-caprolactone/?-valerolactone monomer with mercapto alcohol evenly with appropriate organic solution under moistureless conditions, and continuously transferring the prepared mixing solution into a micro-reaction device supported with an immobilized enzyme for polymerization to synthetize a poly (?-caprolactone/?-valerolactone). Compared with the prior art, the present invention achieves a continuous production by using immobilized lipase Novozyme435 as a catalyst.
Type:
Application
Filed:
November 16, 2016
Publication date:
March 16, 2017
Applicant:
NANJING TECH UNIVERSITY (CN)
Inventors:
Kai GUO, Weijun Huang, Ning Zhu, Xin Hu, Zheng Fang, Yihuan Liu
Abstract: A method for preparing caprolactam by using a microreactor under Lewis acid catalysis, wherein a hydroxyl group in a cyclohexanone oxime is activated to obtain a cyclohexanone oxime sulfonates intermediate, then rearranged under Lewis acid catalysis to prepare the caprolactam. The method of this invention has a simple process and a high operation safety and selectivity, the reaction condition is mild, an efficient reaction can take place even at room temperature, the reaction time is short, the conversion of the cyclohexanone oxime can reach 100% within a short time, the selectivity of the caprolactam can reach 99%, the energy consumption is greatly reduced in the premise of maintaining a high yield, and the production cost is reduced, being an efficient and green and environmentally friendly method of for synthesizing the caprolactam.
Type:
Application
Filed:
June 24, 2016
Publication date:
January 12, 2017
Applicant:
NANJING TECH UNIVERSITY (CN)
Inventors:
Kai Guo, Xin Li, Zheng Fang, Kai Zhang, Qi Yu, Pingkai Ouyang
Abstract: A method for preparing a high-quality epoxidized fatty acid ester with a micro-reaction device, including: respectively pumping an aqueous hydrogen peroxide solution and a carboxylic acid at the same time into a first micro-mixer; after the reaction in the first micro-reactor, respectively pumping the output material and an unsaturated fatty acid ester into a second micro-mixer; completely mixing them and then introducing the mixture into a second micro-reactor; and after a complete reaction, water-rinsing the organic phase part of the resultant reaction liquid and drying the same to obtain the epoxidized fatty acid ester.
Type:
Application
Filed:
July 1, 2016
Publication date:
October 27, 2016
Applicant:
NANJING TECH UNIVERSITY (CN)
Inventors:
Kai Guo, Zheng Fang, Xin Li, Ning Zhu, Li Wan, Wei He, Kai Zhang, Pingkai Ouyang
Abstract: It discloses a vanadium-titanium compound material with high thermal stability and high activity and a preparation method thereof. The vanadium-titanium compound material is mainly composed of vanadium oxide and titanium oxide, where the content of vanadium oxide is 0.5% to 30% by mass of the vanadium-titanium compound material, and the crystal form of titanium oxide in the vanadium-titanium compound material is one of anatase and TiO2(B) or a mixture thereof.