Patents Assigned to Nankai University
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Patent number: 10053531Abstract: This invention provides molecularly imprinted polymer nanoparticles compatible with biological samples, and in particular pure biological samples and a preparation method thereof. Said molecularly imprinted polymer nanoparticles have a crosslinking degree exceeding 50%, a particle diameter of 10 to 500 nm, hydrophilic polymer brushes on its surfaces and can be prepared by introducing appropriate hydrophilic macromolecular chain transfer agents into reversible addition-fragmentation chain transfer (RAFT) precipitation polymerization systems through the one-pot synthesis. The preparation method is simple, features a broad range of application and yields a pure product. The obtained hydrophilic molecularly imprinted polymer nanoparticles have prospects for a wide range of application in biological sample analysis, medical clinical immune analysis, food and environmental monitoring, biomimetic sensors, etc.Type: GrantFiled: November 20, 2013Date of Patent: August 21, 2018Assignee: NANKAI UNIVERSITYInventors: Huiqi Zhang, Yue Ma, Ying Zhang, Guoqing Pan
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Patent number: 10036102Abstract: A bismuth and magnesium co-doped lithium niobate crystal includes Li2CO3, Nb2O5, Bi2O3 and MgO, wherein the molar ratio of [Li] and [Nb] is 0.90-1.00, the molar percentage of Bi2O3 in the mixture is 0.25-0.80%, and the molar percentage of MgO in the mixture is 3.0-7.0%. The bismuth and magnesium co-doped lithium niobate crystal has enhanced photorefraction, improved photorefractive sensitivity, shortened holographic grating saturation writing time, and the photorefractive diffraction efficiency can reach up to 17%. The response time is only 170 ms, when the holographic storage experiment is carried out using 488 nm continuous laser. Therefore, this crystal can be used in the field of holographic imaging.Type: GrantFiled: December 7, 2016Date of Patent: July 31, 2018Assignees: NANKAI UNIVERSITY, TAISHAN SPORTS INDUSTRY GROUP CO., LTD.Inventors: Yongfa Kong, Dahuai Zheng, Shiguo Liu, Jingjun Xu, Peiming Xu, Zhiyong Bian, Shaolin Chen, Ling Zhang, Hongde Liu
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Publication number: 20170306348Abstract: This disclosure provides a stress-responsive polypeptide sequence for fusion with a polypeptide to specifically induce stability of the fusion polypeptide under stress conditions, such as drought, high salt and high temperature, in plants. Also disclosed includes an expression vector for expressing a fusion polypeptide comprising the stress-responsive peptide in plants transformed therewith, and a method for generating a transgenic plant with enhanced tolerance to environmental stresses, comprising introducing into the transgenic plant a polynucleotide encoding a fusion polypeptide which comprises the stress-responsive peptide as disclosed and a plant anti-stress gene, such as the plant senescence-associated gene SSPP. A plant expressing the expression vector that have an enhanced stress tolerance, including Arabidopsis and soybean, is also provided.Type: ApplicationFiled: July 8, 2017Publication date: October 26, 2017Applicant: NANKAI UNIVERSITYInventors: NINGNING WANG, LI XIONG, JUANJUAN BI, SHENG LIU, WEI XU, LIFANG SUN, ZHAOXIA GUO, NASRULLAH, DAN WANG, YUANYUAN MEI
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Publication number: 20160326166Abstract: The present invention relates to ?-carboline, dihydro-?-carboline and tetrahydro-?-carboline alkaloid derivatives (I) and a method for preparing same and the use in the aspects of preventing and treating plant viruses, fungicides and insecticides. For the meaning of each group in formula (I) see the description. The ?-carboline, dihydro-?-carboline and tetrahydro-?-carboline alkaloid derivatives of the present invention show a particularly ourstanding anti-plant virus activity, and also have fungicidal and insecticidal activities.Type: ApplicationFiled: December 24, 2014Publication date: November 10, 2016Applicants: NANKAI UNIVERSITY, NATIONAL PESTICIDE ENGINEERING RESEARCH CENTER (TIANJIN)Inventors: Qingmin Wang, Hongjian Song, Yongxian Liu, Yuxiu Liu
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Patent number: 9333382Abstract: A plant-microorganism combined method for phhytoremediation of organic contaminated soil; i.e., an ornamental plant (Impatiens balsamina L.)—microorganisms (petroleum hydrocarbon degrading mixed microbes) combined method for enhanced phytoremediation of petroleum contaminated soil is disclosed. The inoculated petroleum degrading mixed microbes can not only degrade contaminants in soil directly but also secretes chemical substances which are helpful to relieve the toxic effects on the Impatiens balsamina L. In return, the Impatiens balsamina L. releases photosynthesis products into the soil, so as to enhance microbial activity and quantity, and assist the microorganisms in degrading target contaminates more effectively and efficiently. Repeating the processes mentioned above is able to continuously reduce petroleum hydrocarbon contaminants in the soil until the residual content of contaminants meets the environmental safety standard.Type: GrantFiled: April 13, 2014Date of Patent: May 10, 2016Assignees: ZHEJIANG ZEHAN ENVIRONMENTAL TECHNOLOGY CO., LTD, Nankai UniversityInventors: Zhang Cai, Qixing Zhou, Lijuan Cheng, Ruiren Zhou, Xin Wang, Jingchun Tang, Qingmin Zhang, Jie Liu, Weitao Liu, Junjie Yang
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Patent number: 9184315Abstract: Receptor type oligothiopene compounds, methods of preparing the compounds, and use of the compounds in photoelectric materials.Type: GrantFiled: March 7, 2012Date of Patent: November 10, 2015Assignee: NANKAI UNIVERSITYInventors: Yongsheng Chen, Xiangjian Wan, Yongsheng Liu, Zhi Li, Jiaoyan Zhou, Fei Wang, Guangrui He, Guankui Long
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Patent number: 9173852Abstract: Disclosed are a hepatic targeted drug delivery system and a process for preparing the same. Also disclosed is a method for treating liver cancer.Type: GrantFiled: December 18, 2008Date of Patent: November 3, 2015Assignees: TIAN SI POLYMER MATERIALS TECHNOLOGY DEVELOPMENT CO., NANKAI UNIVERSITYInventors: Zhi Yuan, Wei Huang, Qin Tian, Chuangnian Zhang, Liang Han, Tong Liu, Yue Zhang, Yue Chen
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Publication number: 20150104855Abstract: A plant-microorganism combined method for phhytoremediation of organic contaminated soil; i.e., an ornamental plant (Impatiens balsamina L.)—microorganisms (petroleum hydrocarbon degrading mixed microbes) combined method for enhanced phytoremediation of petroleum contaminated soil is disclosed. The inoculated petroleum degrading mixed microbes can not only degrade contaminants in soil directly but also secretes chemical substances which are helpful to relieve the toxic effects on the Impatiens balsamina L. In return, the Impatiens balsamina L. releases photosynthesis products into the soil, so as to enhance microbial activity and quantity, and assist the microorganisms in degrading target contaminates more effectively and efficiently. Repeating the processes mentioned above is able to continuously reduce petroleum hydrocarbon contaminants in the soil until the residual content of contaminants meets the environmental safety standard.Type: ApplicationFiled: April 13, 2014Publication date: April 16, 2015Applicant: Nankai UniversityInventors: Zhang Cai, Qixing Zhou, Lijuan Cheng, Ruiren Zhou, Xin Wang, Jingchun Tang, Qingmin Zhang, Jie Liu, Weitao Liu, Junjie Yang
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Metal-catalyzed copolymerization of imines and carbon monoxide as a route to synthesize polypeptides
Patent number: 8815913Abstract: Polypeptides of formula (I): wherein R1 and R2 are substituents independently selected from substituted and un-substituted alkyl groups and substituted and un-substituted aryl groups, and n is an integer greater than or equal to 2. Synthesis methods are also provided that do not use amino acids as starting materials, but instead employ imines and carbon monoxide as monomers that undergo transition metal-catalyzed alternating copolymerization to directly provide polypeptides using an acylcobalt catalyst with the following structural formula: wherein R is selected from the group consisting of alkyl, phenyl, and substituted phenyl groups.Type: GrantFiled: June 8, 2009Date of Patent: August 26, 2014Assignee: Nankai UniversityInventors: Huailin Sun, Jian Zhang, Qiuhua Liu, Lei Yu, Jiangyu Zhao -
Publication number: 20140142308Abstract: Receptor type oligothiopene compounds, methods of preparing the compounds, and use of the compounds in photoelectric materials.Type: ApplicationFiled: March 27, 2012Publication date: May 22, 2014Applicant: NANKAI UNIVERSITYInventors: Yongsheng Chen, Xiangjian Wan, Yongsheng Liu, Zhi Li, Jiaoyan Zhou, Fei Wang, Guangrui He, Guankui Long
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Patent number: 8466298Abstract: Provided are a kind of high selectivity polymeric adsorbents with amide functional groups based on the hydrogen bonding interaction, which is prepared by adequately swelling a DVB-co-MA copolymer of 6% crosslinking degree as the initial resin with dimethyl formamide, performing an amination reaction by adding a diamine, soaking the dried resultant yellow resin with an acylating agent that is a dianhydride, and performing an acylation reaction to obtain the polymeric adsorbent with amide functional groups of the invention. The polymeric adsorbent of the invention can be used to effectively isolate and purify the active ingredients, i.e., flavones and lactones, from the extract of ginkgo leaf.Type: GrantFiled: February 12, 2009Date of Patent: June 18, 2013Assignee: Nankai UniversityInventors: Zhi Yuan, Chunhong Wang, Rongfu Shi, Jing Zhang, Ping Ren, Yingchao Chen
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Publication number: 20130109749Abstract: The present invention provides a compound of formula (I)Type: ApplicationFiled: April 14, 2011Publication date: May 2, 2013Applicants: NANKAI UNIVERSITY, ACCENDATECHInventors: Yue Chen, Quan Zhang, Yaxin Lu, Jiadai Zhai, Yahui Ding, Jing Long, Hongxia Fan, Haoliang Zhang, Miao Wang, Weiwei Ma
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Publication number: 20110286147Abstract: An electrode material comprising 0.5-50 wt % functionalized graphene material and a capacitor comprising the electrode material are provided. A method for preparing the functionalized graphene material is also provided. The method comprises the step of chemically reducing the soluble graphene material and the step of physically reducing the chemically reduced graphene material.Type: ApplicationFiled: October 26, 2009Publication date: November 24, 2011Applicants: TIANJIN PULAN NANO TECHNOLOGY CO., LTD., NANKAI UNIVERSITYInventors: Yongsheng Chen, Yi Huang, Yan Wang, Yanfeng Ma
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Publication number: 20110218346Abstract: Provided are a kind of high selectivity polymeric adsorbents with amide functional groups based on the hydrogen bonding interaction, which is prepared by adequately swelling a DVB-co-MA copolymer of 6% crosslinking degree as the initial resin with dimethyl formamide, performing an amination reaction by adding a diamine, soaking the dried resultant yellow resin with an acylating agent that is a dianhydride, and performing an acylation reaction to obtain the polymeric adsorbent with amide functional groups of the invention. The polymeric adsorbent of the invention can be used to effectively isolate and purify the active ingredients, i.e., flavones and lactones, from the extract of ginkgo leaf.Type: ApplicationFiled: February 12, 2009Publication date: September 8, 2011Applicant: NANKAI UNIVERSITYInventors: Zhi Yuan, Chunhong Wang, Rongfu Shi, Jing Zhang, Ping Ren, Yingchao Chen
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Publication number: 20110004582Abstract: A method of constructing the intelligent computer systems based on information reasoning, the method comprising the steps of: obtaining the problem from the users and analyzing the corresponding user demands; choosing the data relating to the user demands in databases and collecting the external data for solving the problems; preprocessing the data and generating the data tables; computing the field of probability on the basis of data tables; computing the degree of credibility of the information reasoning rule according to the new information theory; outputting the information reasoning rule “if A, then B” and its degree of credibility; storing the results of the discovered information reasoning rules. The intelligent computer systems constructed by this patent can extract information from the large amount of data automatically.Type: ApplicationFiled: July 2, 2010Publication date: January 6, 2011Applicant: Nankai UniversityInventor: Guoding HU
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METAL-CATALYZED COPOLYMERIZATION OF IMINES AND CARBON MONOXIDE AS A ROUTE TO SYNTHESIZE POLYPEPTIDES
Publication number: 20090264619Abstract: Polypeptides of formula (I): wherein R1 and R2 are substituents independently selected from substituted and un-substituted alkyl groups and substituted and un-substituted aryl groups, and n is an integer greater than or equal to 2. Synthesis methods are also provided that do not use amino acids as starting materials, but instead employ imines and carbon monoxide as monomers that undergo transition metal-catalyzed alternating copolymerization to directly provide polypeptides using an acylcobalt catalyst with the following structural formula: wherein R is selected from the group consisting of alkyl, phenyl, and substituted phenyl groups.Type: ApplicationFiled: June 8, 2009Publication date: October 22, 2009Applicant: NANKAI UNIVERSITYInventors: Huailin SUN, Jian Zhang, Qiuhua Liu, Lei Yu, Jiangyu Zhao -
Publication number: 20090148881Abstract: The invention provides a strain of Geobacillus thermodenitrificans as well as the screening method and the uses thereof. The strain was deposited as the number CGMCC-1228 in the China General Microbiological Culture Collection Center of the China Committee of Culture Collection for Microorganisms. The strain was obtained by primary screening, re-screening, inoculation, domestication and propagation using the bacteria in the aqueous samples from the strata of oil field as the original screening strain. The strain screened in the invention belongs to the genus Geobacillus, which can tolerate a high temperature, and has good thermostability, which can be applied to the industrial production which need the condition of thermostable enzymes, such as fermentation, etc. With its ability of growing well in the oil-reservoir environment, degrading alkanes, decreasing viscosity and increasing fluidity of crude oil, the strain is able to remarkably enhance the yield of oil and improve the transporting efficiency of oil.Type: ApplicationFiled: March 22, 2005Publication date: June 11, 2009Applicant: NANKAI UNIVERSITYInventors: Lei Wang, Rulin Liu, Lu Feng, Fenglai Liang
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Patent number: 6835368Abstract: This invention relates to the field of materials of the photorefractive crystal. The composition of these crystals is Li1−xNb1+yO3: Fem, Mn, where M can be magnesium, indium, or zinc; when using q to denote the ion valence of M (q=2 when M is Mg or Zn, and q=3 when M is In), the values of x, y, m, and n are in the range of 0.05≦x≦0.13, 0.00≦y≦0.01, 5.0×10−5≦m≦7.5×10−4, and 0.02≦qn≦0.13. This invention greatly improves the photorefractive properties of LiNbO3 crystals: makes it have a high diffraction efficiency (more than 68%), a fast response speed for photorefraction (an order of magnitude faster than iron doped LiNbO3), and a high resistance to optical scattering (the light intensity threshold to photorefractive fan scattering near two orders of magnitude larger than LiNbO3: Fe). This invention is an excellent three-dimensional optical storage material and has a vast potential market.Type: GrantFiled: June 18, 2001Date of Patent: December 28, 2004Assignee: Nankai UniversityInventors: Yongfa Kong, Jingjun Xu, Guangao Li, Qian Sun, Baiquan Tang, Hui Huang, Ziheng Huang, Shaolin Chen, Xiaojun Chen, Guangyin Zhang
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Patent number: 6738337Abstract: The invention relates to the information storage. It consists of a computer, a precise rotary table, a writing laser source, a readout laser source, a spatial filter, a spatial light modulator, lens, mirrors, photorefractive crystals (such as doubly doped lithium niobate), and a phase-mismatch adjustor; Due to used a green light (532 nm) as the writing light, and a red light (670 nm) as the readout light, the signal-to-noise ratio is improved greatly and the problem of fixing the stored information is solved. The transmission configuration is used to realize the high-density digital storage in which the irregular lens is designed to work as a phase-mismatch adjustor and read out the whole stored image with no distortion and loss. The dynamically differential encoding and decoding technique is used to suppress the bit-error-rate to lower than 10−6.Type: GrantFiled: June 8, 2001Date of Patent: May 18, 2004Assignee: Nankai UniversityInventors: Jingjun Xu, Qian Sun, Xinzheng Zhang, Hui Huang, Qiang Wu, Baiquan Tang, Haijun Qiao, Guangyin Zhang, Zuojin Sha
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Publication number: 20020018429Abstract: The invention relates to the information storage. It consists of a computer, a precise rotary table, a writing laser source, a readout laser source, a spatial filter, a spatial light modulator, lens, mirrors, photorefractive crystals (such as doubly doped lithium niobate), and a phase-mismatch adjustor; Due to used a green light (532 nm) as the writing light, and a red light (670 mn) as the readout light, the signal-to-noise ratio is improved greatly and the problem of fixing the stored information is solved. The transmission configuration is used to realize the high-density digital storage in which the irregular lens is designed to work as a phase-mismatch adjustor and read out the whole stored image with no distortion and loss. The dynamically differential encoding and decoding technique is used to suppress the bit-error-rate to lower than 10−6.Type: ApplicationFiled: June 8, 2001Publication date: February 14, 2002Applicant: NANKAI UNIVERSITYInventors: Jingjun Xu, Qian Sun, Xinzheng Zhang, Hui Huang, Qiang Wu, Baiquan Tang, Haijun Qiao, Guangyin Zhang