Patents Assigned to National Institute of Radiological Sciences
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Patent number: 8106366Abstract: Provided are an ion beam control apparatus and a control method for controlling an ion beam energy expansion level and an ion beam size in a radial direction. An ion beam control apparatus Sa is provided with an ion beam generating unit 2, and an ion beam control unit 1a in which a generated ion beam (IB) is input and controlled to be output with the prescribed level of energy expansion and the prescribed diameter in the radial direction. In the ion beam control unit 1a, phase rotation by a radio frequency electric field that increases existing probability with the prescribed level of energy is at least used.Type: GrantFiled: May 20, 2008Date of Patent: January 31, 2012Assignees: Kyoto University, National Institute of Radiological SciencesInventors: Akira Noda, Toshiyuki Shirai, Masahiro Ikegami, Shu Nakamura, Hiroyuki Daido, Kouji Noda
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Patent number: 8106362Abstract: A surface contamination examining device includes a radiation detector 11 and an arithmetic/display device 13 for displaying radiation intensity in form of a counting rate. The arithmetic/display device has a boundary detecting device 10 that detects the boundary of contamination 14 of an object to be measured by a radioactive material while the radiation detector moves along a surface 18 of the object to be measured.Type: GrantFiled: March 30, 2007Date of Patent: January 31, 2012Assignee: National Institute of Radiological SciencesInventor: Yoshiyuki Shirakawa
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Patent number: 8067648Abstract: A phenyl tin compound is synthesized by using a derivative having various functional groups and a bromo- or iodo-benzene ring as a labeling material of a radioactive ligand. On the other hand, a novel hydroxytosyl iodobenzene compound having an electron-donating group is obtained by oxidizing iodobenzene having one or more electron-donating groups and reacting it with tosylic acid. Then, a diphenyliodonium salt which is a labeling precursor is synthesized by reacting the resulting compound with various phenyl tin compounds. Finally, a 18F-labeled ligand having various functional groups and a [18F] fluorobenzene ring is synthesized by reacting the resulting diphenyliodonium salt with [18F]F?.Type: GrantFiled: November 29, 2006Date of Patent: November 29, 2011Assignee: National Institute of Radiological SciencesInventors: Kazutoshi Suzuki, Ming-Rong Zhang, Katsushi Kumata
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Publication number: 20110224534Abstract: A PET/MRI device includes an MRI device that has a measurement port, a PET detector that can be inserted into the measurement port, and a mechanism that can slide the PET detector into and out of the MRI measurement port. Thereby, the PET/MRI device allows MRI measurement during PET measurement.Type: ApplicationFiled: December 3, 2010Publication date: September 15, 2011Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventors: Taiga YAMAYA, Takayuki OBATA
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Publication number: 20110127435Abstract: A gamma ray detector for detecting a gamma ray emitted from a target of measurement includes: an organic scintillator for detecting Compton electrons resulting from a gamma ray emitted from the target of measurement; an inorganic scintillator for detecting a Compton gamma ray; and photodetector modules for detecting light generation in the corresponding scintillators. Light generation signals from the organic and inorganic scintillators are synchronously measured, and a detection window of a gamma ray is generated. Thus, an inexpensive radiation diagnostic device of an ultra-high S/N ratio and low cost is provided.Type: ApplicationFiled: June 25, 2009Publication date: June 2, 2011Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventor: Hidehito Nakamura
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Publication number: 20110121184Abstract: In a DOI radiation detector, scintillation crystals are arranged in three dimensions on a light receiving surface of a light receiving element, and a response of a crystal having detected a radiation ray can be identified on the light receiving surface. Thereby, a position at which the radiation ray is detected is determined in three dimensions. In this DOI radiation detector, regular triangular prism scintillation crystals are used, and response positions of the respective crystals are shifted for each set. This allows crystal identification without loss even with a structure such as a three-layer or six-layer structure hard to achieve by a quadrangular prism scintillation crystal.Type: ApplicationFiled: July 16, 2008Publication date: May 26, 2011Applicants: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES, SHIMADZU CORPORATIONInventors: Naoko Inadama, Hideo Murayama, Kengo Shibuya, Fumihiko Nishikido, Tomoaki Tsuda
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Publication number: 20110101229Abstract: This aims to provide a DOI type radiation detector in which scintillation crystals arranged two-dimensionally on a light receiving surface to form rectangular section groups in extending directions of the light receiving surface of a light receiving element are stacked up to make a three-dimensional arrangement and responses of the crystals that have detected radiation are made possible to identify at response positions on the light receiving surface, so that a three-dimensional radiation detection position can be obtained. In the DOI type radiation detector, scintillation crystals are right triangle poles extending upwards from the light receiving surface and the response positions on the light receiving surface are characterized. With this structure, DOI identification of a plurality of layers can be carried out by simply performing an Anger calculation of a light receiving element signal.Type: ApplicationFiled: October 8, 2008Publication date: May 5, 2011Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventors: Naoko Inadama, Hideo Murayama, Kengo Shibuya, Fumihiko Nishikido, Taiga Yamaya, Eiji Yoshida
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Publication number: 20110092814Abstract: A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.Type: ApplicationFiled: August 1, 2008Publication date: April 21, 2011Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventors: Taiga Yamaya, Hideo Murayama, Taku Inaniwa
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Publication number: 20110084211Abstract: In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.Type: ApplicationFiled: August 1, 2008Publication date: April 14, 2011Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventors: Taiga Yamaya, Hideo Murayama, Shinichi Minohara, Taku Inaniwa, Takuji Furukawa, Shinichirou Mori
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Patent number: 7919759Abstract: A charged particle beam 2 which enters a final bending electromagnet 7 after traveling through quadrupole electromagnets 4, 5, 6 travels through the final bending electromagnet 7 in an arc shape path by increasing or decreasing a bending magnetic field generated in the final bending electromagnet 7, with a pre-determined period for example and is scanned in an X-direction. The charged particle beam 2 scanned in the X-direction is scanned in a Y-direction while traveling through a Y-direction Wobbler electromagnet 8. Consequently, the charged particle beam 2 is scanned in the X-direction and the Y-direction, and the target 9 is irradiated with the charged particle beam 2 so that a round field is drawn, for example.Type: GrantFiled: October 31, 2005Date of Patent: April 5, 2011Assignee: National Institute of Radiological SciencesInventors: Takuji Furukawa, Kouji Noda
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Publication number: 20110031407Abstract: In an open-type PET scanner including a plurality of detector rings having multiple rings arrayed in the body axis direction, radiation measurement is performed while at least one detector ring is relatively moved with respect to a subject in the body axis direction, thereby dispersing simultaneous radiation in an open region to suppress a local reduction in sensitivity. The detector rings are optimized in constitution, moving direction and/or moving speed, thus making it possible to reduce the variation of distribution of sensitivity and expand a clearance in the open region and a field-of-view in the body axis direction.Type: ApplicationFiled: May 2, 2008Publication date: February 10, 2011Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventors: Taiga Yamaya, Hideo Murayama, Shinichirou Mori
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Publication number: 20110024638Abstract: A PET scanner in which detector rings are arrayed in a multilayered manner so as to oppose each other in the body axis direction is provided. In the PET scanner, a predetermined number of detector units, each of which is made up of a predetermined number of detector rings, are arrayed so as to give each other a clearance, and a first ring set in which the clearance is less than or equal to a mean value of widths of two detector units forming each clearance and a second ring set constituted with a predetermined number of detector units are arrayed apart so as to give a clearance which is less than or equal to a mean value of the width of the first ring set and that of the second ring set, thereby imaging a field-of-view including the clearance and continuing in the body axis direction to an entire length of the first ring set and that of the second ring set.Type: ApplicationFiled: April 14, 2008Publication date: February 3, 2011Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventors: Taiga Yamaya, Hideo Murayama
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Publication number: 20110024637Abstract: In an open-type PET scanner, detector rings arranged in a multilayered manner in an axial direction are at least partially opened and the thus opened part of the detector rings is at least partially included in a main focus region. Then, at least some of the detecting elements constituting the detector ring are disposed obliquely in the axial direction so that the main sensitivity direction thereof is turned closer to the main focus region, increasing the resolution in the main focus region. Thereby, it is possible to retain resolution in the body axis direction without using a high-resolution DOI detector and to reduce the price of the open-type PET scanner.Type: ApplicationFiled: April 1, 2008Publication date: February 3, 2011Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventors: Taiga Yamaya, Hideo Murayama, Naoko Inadama
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Patent number: 7868564Abstract: A linearity of a voltage change to a tuner insertion amount is verified for at least one of a plurality of tuners. Based on the voltage change linearity, individual voltage change data corresponding to respective insertion amounts are calculated for each of the plurality of tuners through a proportional calculation. A combination of auto-tuners and a combination of respective insertion amounts of the auto-tuners are determined using the individual voltage change data, and an adequacy of the determined combinations is verified through a direct three-dimensional electromagnetic field calculation. The combinations are determined on a condition that, when the individual voltage change data of nominated tuners are added together, respective voltage changes attributed to the nominated tuners are cancelled out to allow an entire voltage distribution to have substantially no change.Type: GrantFiled: October 31, 2005Date of Patent: January 11, 2011Assignee: National Institute of Radiological SciencesInventors: Yoshiyuki Iwata, Satoru Yamada
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Publication number: 20110001049Abstract: A light receiver for detecting incident time is installed on the side of a radiation source of a scintillator (including a Cherenkov radiation emitter), and information (energy, incident time, an incident position, etc.) on radiation made incident into the scintillator is obtained by the output of the light receiver. It is, thereby, possible to identify an incident position and others of radiation into the scintillator at high accuracy.Type: ApplicationFiled: April 9, 2008Publication date: January 6, 2011Applicant: National Institute of Radiological SciencesInventors: Kengo Shibuya, Taiga Yamaya, Naoko Inadama, Fumihiko Nishikido, Eiji Yoshida, Hideo Murayama
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Publication number: 20100308225Abstract: Provided are a beta ray detector and a beta ray reconstruction method capable of achieving consistently high detection efficiency of beta rays in a wider energy region compared to that of a conventional beta ray detector while enhancing energy resolution. The beta ray detector comprises an absorber scintillator 12 which is disposed to face a subject emitting beta rays and is made from an absorptive substance exhibiting a high permeability and a high rate of absorption with respect to beta rays, a backscattering scintillator 14 which is disposed on the backside of the absorber scintillator and is made from a backscattering substance exhibiting a low permeability and a high rate of backscattering with respect to beta rays, and an energy detector 16 which combines the amounts of beta ray energy absorption simultaneously measured by the two types of scintillators to reconstruct the energy and the detection position of the beta rays emitted from the subject.Type: ApplicationFiled: September 21, 2007Publication date: December 9, 2010Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventor: Hidehito Nakamura
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Publication number: 20100301221Abstract: Provided are a gamma ray detector and a gamma ray reconstruction method which can be used in SPECT and PET and which combine and reconstruct the information on “Compton-scattered” gamma rays, thereby remarkably increasing gamma ray detection sensitivity, decreasing the amount of a radioactive substance given to a subject, and remarkably reducing the concern about the amount of radiation exposure. The gamma ray detector comprises an absorber scintillator 12 made from an absorptive substance exhibiting a high rate of absorption with respect to gamma rays 1 in an energy region, emitted from a subject, a Compton scattering scintillator 14 made from a Compton scattering substance exhibiting a high probability of Compton scattering, and an energy detector 16 which combines the amounts of gamma ray energy absorption simultaneously measured by the two types of scintillators to reconstruct the gamma rays emitted from the subject.Type: ApplicationFiled: May 15, 2007Publication date: December 2, 2010Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventor: Hidehito Nakamura
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Publication number: 20100274512Abstract: When an energy of a particle emitted from a radioisotope source is obtained by a detector, a histogram obtained from a relationship between a difference ?E between an energy of a particle emitted outside the radioisotope source and an initial energy which the particle possesses at the time of generation and a count is treated as being asymmetric, and an energy distribution (L1) of the particle emitted outside the radioisotope source is obtained, thereby allowing an energy calibration of a radiation detector, absolute quantitation and resolution measurement to be performed with accuracy.Type: ApplicationFiled: October 22, 2008Publication date: October 28, 2010Applicant: NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventor: Hidehito Nakamura
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Patent number: 7817288Abstract: A device for measuring profiles of an electron beam and a laser beam is provided with a profile measuring device 30 for measuring cross-section profiles of the beams in the vicinity of a collision position where an electron beam 1 and a laser beam 3 are brought into frontal collision, and a moving device 40 for continuously moving the profile measuring device in a predetermined direction which substantially coincides with the axial directions of the beams. Furthermore, based on the cross-section profiles measured by the profile measuring device, the position of the profile measuring device in the predetermined direction, and the oscillation timings of the beams, temporal changes in three-dimensional profiles of the electron beam and the laser beam are created by a profile creating device 50.Type: GrantFiled: March 7, 2007Date of Patent: October 19, 2010Assignees: IHI Corporation, The University of Tokyo, National Institute of Radiological SciencesInventors: Daisuke Ishida, Hiroyuki Nose, Namio Kaneko, Mitsuru Uesaka, Fumito Sakamoto, Katsuhiro Dobashi
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Publication number: 20100237239Abstract: In order to attain an object to realize an ion beam capable of (i) immediately determining energy of the ion beam to be generated, and (ii) measuring an ion beam in real time while carrying out laser irradiation, an ion beam detector (1) of the present invention includes a light conversion section (7) transmitting X-rays mixed in with ions (3) and converting the ions (3) to light; a light detection section (9) detecting, as an electric signal, the light converted from the ions (3) by the light converting section (7); a time-of-flight measurement section (10) measuring a time of flight for the ions (3) to reach the light conversion section (7); an electron removal section (5) removing electrons mixed in with the ions (3) and a light shielding section (6) shielding light mixed in with the ions (3), each of which is provided in an upstream of the light conversion section from which the ion beam comes to the light conversion section; and a curved section (8) between the light conversion section (7) and the lightType: ApplicationFiled: February 14, 2007Publication date: September 23, 2010Applicants: KYOTO UNIVERSITY, NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCESInventors: Akira Noda, Yoshihisa Iwashita, Shu Nakamura, Hiroyuki Daido, Satoru Yamada