Abstract: A radiation measuring device capable of identifying the incident direction of a radiation ray and energy (segmentation). The directivity characteristics of a plurality of detectors are different from each other. A plurality of energy segmentations are set respectively for a plurality of spectra corresponding to a plurality of detectors, and actual measurement ratio information (a plurality of actual measurement counting ratios) expressing the mutual ratio between integrated counting values for each energy segmentation is computed. The actual measurement ratio information is checked against a plurality of response functions, and, when the compatibility relation between specific actual measurement ratio information and specific theoretical ratio information is found, the incident direction of a radiation ray and an energy segmentation are identified based on that relation.

Abstract: There is provided a method for preparing an analytical standard used for microbeam X-ray fluorescence analysis which includes: a mixing step in which an element is added to a base material, and the base material and the element are mixed by stirring to obtain a mixed solution; a deaeration step in which the mixed solution is deaerated; a freeze step in which the mixed solution is slowly frozen; and a cutting step in which a thin section is cut out from the frozen mixed solution. In order to surely remove bubbles from the mixed solution, the deaeration step may contain a stationary step in which the mixed solution is allowed to stand still at room temperature; or the stationary step includes a removal step in which gas contained in the mixed solution which is allowed to stand still is removed with a suction apparatus.

Abstract: Provided are an ion beam control apparatus and a control method for controlling an ion beam energy expansion level and an ion beam size in a radial direction. An ion beam control apparatus Sa is provided with an ion beam generating unit 2, and an ion beam control unit 1a in which a generated ion beam (IB) is input and controlled to be output with the prescribed level of energy expansion and the prescribed diameter in the radial direction. In the ion beam control unit 1a, phase rotation by a radio frequency electric field that increases existing probability with the prescribed level of energy is at least used.

Abstract: A DNA chip and a prediction method for predicting the occurrence of a late adverse reaction in a urinary organ after C-ion RT are provided. The DNA chip comprises a supporting means for supporting a DNA probe thereon, and a plurality of genetic markers supported on the supporting means.

Abstract: A plurality of detector rings in which detectors arranged densely or spatially in a ring shape or in a polygonal shape are arranged, with an open space kept in the body axis direction, coincidences are measured for some of or all of detector pairs connecting the detector rings apart from the open space to perform three-dimensional image reconstruction, thereby imaging the open space between the detector rings as a tomographic image. Therefore, the open space is secured, with the deteriorated quality of an image suppressed, thus making it possible to easily gain access to a patient under PET scanning from outside a gantry and also provide irradiation of particle beams for cancer treatment as well as X-ray CT scanning.

Abstract: A multi-color X-ray generator includes an electron beam generator 10 which accelerates an electron beam to generate a pulse electron beam 1 and which transmits the beam along a predetermined rectilinear orbit 2, a composite laser generator 20 which successively generates a plurality of pulse laser lights 3a, 3b having different wavelengths, and a laser light introduction device 30 which introduces the pulse laser lights along the rectilinear orbit 2 to be opposed to the pulse electron beam 1, so that the plurality of pulse laser lights 3a, 3b successively head-on collide with the pulse electron beam 1 along the rectilinear orbit 2 so as to generate two or more types of monochromatic hard X-rays 4 (4a, 4b).

Abstract: In a radiation detector, a response is approximated as a primary delay system, and when a time constant T indicating the characteristic of the response is known, a final response value N0 is forecasted from dose rates or counting rates N1 and N2 of two points in the initial or middle stage of response. When the time constant T is unknown, the final response value N0 is forecasted from dose rates or counting rates N1, N2, and N3 of three points in the initial or middle stage of response. Simultaneously, a time constant is obtained and the soundness of the radiation detector is also evaluated. Thereby, a dose rate in an existence field of radiation or a counting rate in an existence field of radioactive materials is quickly and accurately forecasted, whereby the measurement time is shortened.

Abstract: Brain-localizing polypeptides carrying a reactive group for linking to a molecule that does not have brain-localizing activity were successfully produced by introducing at least two lysine residues into cyclized polypeptides having a brain-localizing motif sequence. These polypeptides have improved metabolic stability compared to conventional brain-localizing polypeptides, and can efficiently translocate desired molecules into the brain.

Abstract: When a repeatedly periodically moving site of a to-be-examined subject in a gantry is subjected to computed tomography and is reconstructed, the gantry is rotated in synchronization with the movement of the periodically moving site, and a dynamic image showing a transient phenomenon is obtained in which the periodic movement of the moving site has been stopped. As a result, the flow of a contrast agent or the like can be observed in a state of stopping the movement of an internal organ that moves repeatedly periodically.

Abstract: A medium area (S) filled with liquid xenon (2) is formed between an external cylindrical body (1a) and internal cylindrical body (1b), and a pair of anode pads (11, 12) are disposed in two-dimensional form in opposite end portions of the medium area (S) in the intersection direction with respect to the gamma-ray incident direction. An intermediate electrode (10) is disposed between a pair of anode pads (11, 12), and a plurality of photomultiplier tubes (5) is installed in two-dimensional form in the external cylindrical body (1a). Then, the gamma-ray reaction point within the liquid area (S) is identified from signals output from the anode pads (11, 12) and photomultiplier tubes (5).

Abstract: A method for amplifying genomic DNA is provided. The method comprises the steps of: (1) incubating a cell-containing agarose solution at a pH of 9 to 12 and a temperature of 45 to 80° C. to produce a genomic DNA-dispersed agarose solution wherein 0.002 to 1 copies/5 microliter of single-stranded genomic DNA is dispersed; (2) solidifying the genomic DNA-dispersed agarose solution to produce a genomic DNA-dispersed agarose gel and neutralizing a pH of the gel; and (3) adding a DNA polymerase with strand displacement activity, primer and dNTP to the genomic DNA-dispersed agarose gel and incubating the gel at a temperature of 0 to 60° C. to amplify the genomic DNA.

Abstract: A positron emission tomography (PET) scanner is provided which uses information on the time-of-flight difference (TOF) between annihilation radiations for image reconstruction. The scanner has detection time correction information (memory) corresponding to information on coordinates in a radiation detection element (e.g., scintillator crystal), in the depth and lateral directions, at which an interaction has occurred between an annihilation radiation and the crystal. Reference is made to the detection time correction information, thereby providing information on time-of-flight difference with improved accuracy. As such, an improved signal to noise ratio and spatial resolution are provided for image reconstruction using time-of-flight (TOF) difference.

Abstract: Administration of either a tocopherol represented by the general formula (1) or a tocotrienol compound ester derivative before or after exposure to radiation is effective in preventing or treating health disorders caused by the radiation exposure.

Abstract: In a case where an error is included in measurement data corresponding to one or a plurality of detecting elements in a tomography scanner, a system matrix to be calculated or referenced on image reconstruction calculation is corrected in accordance with the error. Thus, even when an error such as a defect or a fault occurs in a detector, influence of the error is eliminated, thereby reducing an artifact generated in an image. At that time, positional information of the detecting elements including the error and information on the degree of the error are stored in a storage device and referenced inside image reconstruction software, thus making it possible to correct the system matrix in accordance with the error.

Abstract: Upon detection of radiation by using a (three-dimensional) detector capable of distinguishing a detection position in a depth direction and energy, an energy window for distinguishing between a signal and noise is changed depending on the detection position in the depth direction, thus making it possible to obtain scattering components inside the detector. Alternatively, a weight is given to a detection event depending on the detection position in the depth direction and energy information to obtain scattering components inside the detector. Thereby, scattering components inside the detector can be obtained to increase the sensitivity of the detector. In this case, different detecting elements can be used depending on the detection position in the depth direction.

Abstract: A method for screening a substance that affect an internal clock system in an organism, comprising the detection of the expression level of a gene exhibiting a light-inducible and rhythmic expression in a circadian manner, which is typically expressed in the suprachiasmatic nucleus of mammalian, such as for example, Dusp4, Snk, Slc39a6 or Nnat.

Abstract: A direction finding radiation detector for detecting the direction of incidence of radioactive rays, comprising: a plurality of scintillators (41, 42, 43) (101, 102, 103) made of the same material, being arranged to overlap circumferentially at least in part so that they are shadowed by each other from radioactive rays incident in circumferential directions and so that light emitted from one of the scintillators is not incident on the other scintillators; and photoreceptor devices (51, 52, 53) (111, 112, 113) having light receiving surfaces optically coupled to the respective scintillators, wherein a combination of proportions of radioactive rays incident directly on the respective scintillators and radioactive rays incident indirectly thereon, being shadowed by the other scintillators, varies with the direction of incidence circumferentially.

Abstract: A method for amplifying genomic DNA is provided. The method comprises the steps of: (1) incubating a cell-containing agarose solution at a pH of 9 to 12 and a temperature of 45 to 80° C. to produce a genomic DNA-dispersed agarose solution wherein 0.002 to 1 copies/5 microliter of single-stranded genomic DNA is dispersed; (2) solidifying the genomic DNA-dispersed agarose solution to produce a genomic DNA-dispersed agarose gel and neutralizing a pH of the gel; and (3) adding a DNA polymerase with strand displacement activity, primer and dNTP to the genomic DNA-dispersed agarose gel and incubating the gel at a temperature of 0 to 60° C. to amplify the genomic DNA.

Abstract: A surface contamination examining device includes a radiation detector 11 and an arithmetic/display device 13 for displaying radiation intensity in form of a counting rate. The arithmetic/display device has a boundary detecting device 10 that detects the boundary of contamination 14 of an object to be measured by a radioactive material while the radiation detector moves along a surface 18 of the object to be measured.

Abstract: A radiation measuring device capable of identifying the incident direction of a radiation ray and energy (segmentation) The directivity characteristics of a plurality of detectors are different from each other. A plurality of energy segmentations are set respectively for a plurality of spectra corresponding to a plurality of detectors, and actual measurement ratio information (a plurality of actual measurement counting ratios) expressing the mutual ratio between integrated counting values for each energy segmentation is computed. The actual measurement ratio information is checked against a plurality of response functions, and, when the compatibility relation between specific actual measurement ratio information and specific theoretical ratio information is found, the incident direction of a radiation ray and an energy segmentation are identified based on that relation.