Patents Assigned to National Research Council of Canada
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Publication number: 20230174591Abstract: Provided is a recombinant polypeptide comprising a resistin trimerization domain and a polypeptide of interest. Further provided is an expression vector encoding the recombinant polypeptide and a method of expressing the recombinant polypeptide. The polypeptide of interest may be a trimeric viral surface antigen or a portion thereof, such as the ectodomain of the SARS-CoV-2 spike protein. Further provided are compositions, such as immunogenic compositions and vaccines, comprising the recombinant polypeptide.Type: ApplicationFiled: May 18, 2021Publication date: June 8, 2023Applicant: National Research Council of CanadaInventor: Yves DUROCHER
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Patent number: 11661469Abstract: Disclosed is a method of preparing polymer film-metal composites and uses of such composites. The metal can be in the form of a nanoparticle or a film. The methods comprise depositing on a surface, a composition comprising: a cationic metal precursor; a polymer film precursor that comprises a plurality of photopolymerizable groups; and a photoreducer-photoinitiator; then irradiating the composition under conditions to simultaneously reduce the cationic metal and polymerize the photopolymerizable groups to obtain the composite on the surface.Type: GrantFiled: September 25, 2018Date of Patent: May 30, 2023Assignee: National Research Council of CanadaInventors: Lidija Malic, Xuefeng Zhang, Keith Morton, Teodor Veres
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Publication number: 20230159691Abstract: There is provided an erosion protective polyurethane elastomer produced from a polyurethane composition with a polyisocyanate component and an isocyanate-reactive component. The polyisocyanate component has a first isocyanate-terminated prepolymer obtained from the reaction of a first polyol with 1,4-bis(isocyanatomethyl cyclohexane) (1,4-H6XDI) or with a mixture of 1,4-H6XDI and a second aliphatic diisocyanate, an aromatic diisocyanate, and/or an arylalkyl diisocyanate, with at least 50 wt. % of diisocyanate used to produce the prepolymer is aliphatic diisocyanate. The isocyanate-reactive component has at least two low molecular weight (Mw<400 g/mol) diols and a second polyol with hydroxyl groups to react with the prepolymer to produce a polyurethane elastomer. The polyurethane composition having a molar ratio of NCO/OH in the range of 1.00-1.Type: ApplicationFiled: March 8, 2021Publication date: May 25, 2023Applicant: NATIONAL RESEARCH COUNCIL OF CANADAInventor: Naiheng SONG
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Patent number: 11658462Abstract: An integrated optical sensor enables the detection and identification of one or more remote gases using a transmission filter that matches specific absorption features of a remote gas and is detected using a single photodetection element. The sensor comprises an integrated optical component that is characterized by its transmission spectrum which corresponds to absorption or emission features of a target gas over a defined spectral bandpass, and the ability to have a reversibly tunable transmission spectrum. The change in the optical power output from the sensor as the transmission spectrum is tuned is proportional to the optical depth of the target gas absorption lines when viewed with a background light source. The optical power output from the integrated optical component is therefore related to the absorption spectrum of the input light Physical properties of the sensor are tailored to produce a quasi-periodic transmission spectrum that results in a stronger signal contrast for a specific gas.Type: GrantFiled: May 20, 2020Date of Patent: May 23, 2023Assignee: National Research Council of CanadaInventors: Ross Cheriton, Siegfried Janz, Adam Densmore
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Publication number: 20230150188Abstract: Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles non-covalently interacting with at least a portion of a polymer material via ?-? bonding, hydrogen bonding, electrostatic interactions stronger than van der Waals interactions, or any combination thereof. The piezoelectric particles may be dispersed in the polymer material and remain substantially non-agglomerated when combined with the polymer material. The polymer material may comprise at least one thermoplastic polymer, optionally further including a polymer precursor. The compositions may define an extrudable material that is a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste.Type: ApplicationFiled: March 22, 2022Publication date: May 18, 2023Applicants: XEROX CORPORATION, NATIONAL RESEARCH COUNCIL OF CANADAInventors: Sarah J. VELLA, Alexandros VASILEIOU, Yujie ZHU, Edward G. ZWARTZ, Chantal PAQUET
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Publication number: 20230150202Abstract: Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer material comprising at least one thermoplastic polymer, and a plurality of piezoelectric covalently bonded to the at least one thermoplastic polymer and dispersed in at least a portion of the polymer material. The compositions are extrudable and may be pre-formed into a form factor suitable for extrusion. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.Type: ApplicationFiled: March 22, 2022Publication date: May 18, 2023Applicants: XEROX CORPORATION, NATIONAL RESEARCH COUNCIL OF CANADAInventors: Sarah J. VELLA, Alexandros VASILEIOU, Yujie ZHU, Edward G. ZWARTZ, Chantal PAQUET
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Publication number: 20230151210Abstract: Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a polymer matrix comprising a first polymer material and a second polymer material that are immiscible with each other, and a plurality of piezoelectric particles substantially localized in one of the first polymer material or the second polymer material. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer matrix. The compositions may define a form factor such as a composite filament, a composite pellet, or an extrudable composite paste. Additive manufacturing processes using the compositions may comprise forming a printed part by depositing the compositions layer-by-layer.Type: ApplicationFiled: March 22, 2022Publication date: May 18, 2023Applicants: XEROX CORPORATION, NATIONAL RESEARCH COUNCIL OF CANADAInventors: Sarah J. VELLA, Alexandros VASILEIOU, Yujie ZHU, Edward G. ZWARTZ, Chantal PAQUET
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Publication number: 20230135112Abstract: Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles and a polymer material comprising at least one thermoplastic polymer and at least one photocurable polymer precursor. The at least one photocurable polymer precursor may undergo a reaction in the presence of electromagnetic radiation, optionally undergoing a reaction with the piezoelectric particles, in the course of forming the printed part. The piezoelectric particles may be mixed with the polymer material and remain substantially non-agglomerated when combined with the polymer material.Type: ApplicationFiled: March 22, 2022Publication date: May 4, 2023Applicants: XEROX CORPORATION, NATIONAL RESEARCH COUNCIL OF CANADAInventors: Sarah J. VELLA, Alexandros VASILEIOU, Yujie ZHU, Edward G. ZWARTZ, Chantal PAQUET
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Patent number: 11635450Abstract: A method for the patterning and control of single electrons on a surface is provided that includes implementing scanning tunneling microscopy hydrogen lithography with a scanning probe microscope to form charge structures with one or more confined charges; performing a series of field-free atomic force microscopy measurements on the charge structures with different tip heights, where interaction between the tip and the confined charge are elucidated; and adjusting tip heights to controllably position charges within the structures to write a given charge state. The present disclose also provides a Gibb's distribution machine formed with the method for the patterning and control of single electrons on a surface. A multi bit true random number generator and neural network learning hardware formed with the above described method are also provided.Type: GrantFiled: June 29, 2021Date of Patent: April 25, 2023Assignees: Quantum Silicon inc., National Research Council of CanadaInventors: Robert Wolkow, Mohammad Rashidi, Wyatt Vine, Thomas Dienel, Lucian Livadaru, Taleana Huff, Jacob Retallick, Konrad Walus, Jason Pitters, Roshan Achal
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PIEZOELECTRIC COMPOSITES CONTAINING A SACRIFICIAL MATERIAL AND USE THEREOF IN ADDITIVE MANUFACTURING
Publication number: 20230122929Abstract: Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles located in a polymer matrix comprising a first polymer material and a sacrificial material that are immiscible with each other. The sacrificial material, which may comprise a second polymer material, may be removable from the first polymer material under specified conditions. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer matrix. The polymer matrix may be treated to remove the sacrificial material to introduce a plurality of pores. The compositions may have a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste.Type: ApplicationFiled: March 22, 2022Publication date: April 20, 2023Applicants: XEROX CORPORATION, NATIONAL RESEARCH COUNCIL OF CANADAInventors: Sarah J. VELLA, Alexandros VASILEIOU, Yujie ZHU, Edward G. ZWARTZ, Chantal PAQUET, Silvio E. KRUGER, Mohammad RAFIEE, Yujie ZHANG, Thomas LACELLE, Derek ARANGUREN VAN EGMOND, Claudie ROY -
Patent number: 11619132Abstract: A methods and systems for determining a change in condition of a rock bolt. Some methods may comprise, at a first point in time, propagating shear and longitudinal ultrasonic waves along the rock bolt to measure a first time of flight for each of the shear and longitudinal waves, at a second point in time after the first point in time, propagating shear and longitudinal ultrasonic waves along the rock bolt to measure a second time of flight for each of the shear and longitudinal waves, and using the relative changes of the first and second time of flights, determining the change in condition of the rock bolt section.Type: GrantFiled: August 16, 2017Date of Patent: April 4, 2023Assignee: National Research Council of CanadaInventors: Zhigang Sun, Kuo-Ting Wu, Silvio Elton Krüger
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Patent number: 11613464Abstract: A modified boron nitride nanotube (BNNT) comprising pendant hydroxyl (OH) and amino (NH2) functional groups covalently bonded to a surface of the BNNT. Aqueous and organic solutions of these modified BNNTs are disclosed, along with methods of producing the same. The modified BNNTs and their solutions can be used to coat substrates and to make nanocomposites.Type: GrantFiled: October 4, 2018Date of Patent: March 28, 2023Assignee: NATIONAL RESEARCH COUNCIL OF CANADAInventors: Jingwen Guan, Benoit Simard
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Publication number: 20230093537Abstract: An atomic orbital based memory storage is provided that includes a plurality of surface atoms forming dangling bonds (DBs) and a subset of the plurality of surface atoms passivated with spatial control to form covalent bonds with hydrogen, deuterium, or a combination thereof. The atomic orbital based data storage that can be rewritten and corrected as needed. The resulting data storage is also archival and capable of high data densities than any known storage as the data is retained in a binary storage or a given orbital being passivated or a dangling bond (DB). A method of forming and reading the atomic orbital data storage is also provided. The method including selectively removing covalent bonds to form dangling bonds (DBs) extending from a surface atom by hydrogen lithography and imaging the covalent bonds spatially to read the atomic orbital data storage.Type: ApplicationFiled: November 28, 2022Publication date: March 23, 2023Applicants: National Research Council of Canada, Quantum Silicon Inc., The Governors of the University of AlbertaInventors: Roshan Achal, Robert A. Wolkow, Jason Pitters, Martin Cloutier, Mohammad Rashidi, Marco Taucer, Taleana Huff
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Patent number: 11591408Abstract: The present invention relates to compounds, compositions, and methods are provided for covalently linking a cargo molecule, such as a therapeutic or a diagnostic agent, to a glycan in the Fab region of an antibody. Also provided are methods of modeling and producing antibodies having de novo Fab glycosylation sites. Also provided are antibody carrier conjugates, methods of using the conjugates.Type: GrantFiled: November 8, 2018Date of Patent: February 28, 2023Assignee: National Research Council of CanadaInventors: Michel Gilbert, Traian Sulea, Maria L. Jaramillo, Yves Durocher, Maurizio Acchione
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Publication number: 20230053870Abstract: A technique for detection of probes in a microfluidic flow-through chamber involves a plurality of interface pinning reaction vessel formed by micro- or nano-structured relief patterning of a substrate. The relief patterning increases a surface area locally, and defines a plurality of separated interface pinning reaction vessels. The marked detection protocol may be supplied on a single layer of a stacked microfluidic chip, or the chamber may constitute a whole layer. The chip may be designed to be driven mechanically, pneumatically, hydraulically, centrifugally or by capillary action. Each vessel allows for a high density of probes, an effective region for developer-type or fluorescence-based marking, and efficient readout. Suitable probe liquids can be self-limiting to fill one vessel. Suitable developer liquids avoid dye bleeding across vessels during washing.Type: ApplicationFiled: February 8, 2021Publication date: February 23, 2023Applicant: National Research Council of CanadaInventors: Matthias GEISSLER, Keith J. MORTON, Teodor VERES
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Patent number: 11574854Abstract: A distributed inductance integrated field effect transistor (FET) structure, comprising a plurality of FETs. Each FET comprises a plurality of source regions, a gate region having a plurality of gate fingers extending from a gate bus bar, a drain region having a plurality of drain finger extending from a drain bus bar between the plurality of gate fingers, wherein the gate region controls current flow in a conductive channel between the drain region and source region. A first distributed inductor connects the gate regions of adjacent ones of the plurality of FETs; and a second distributed inductor connects the drain regions of adjacent ones of the plurality of FETs.Type: GrantFiled: April 7, 2021Date of Patent: February 7, 2023Assignee: NATIONAL RESEARCH COUNCIL OF CANADAInventor: Nianhua (Frank) Jiang
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Patent number: 11566064Abstract: The present invention relates to hemagglutinin-specific antibodies, fragments thereof, and uses thereof. More specifically, these antibodies and fragments thereof are able to recognize antigen from multiple influenza strains.Type: GrantFiled: January 26, 2018Date of Patent: January 31, 2023Assignee: National Research Council of CanadaInventors: Aziza Manceur, Anne Marcil, Wei Zou, Amine Kamen, Christine Gadoury
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Patent number: 11557337Abstract: An atomic orbital based memory storage is provided that includes a plurality of surface atoms forming dangling bonds (DBs) and a subset of the plurality of surface atoms passivated with spatial control to form covalent bonds with hydrogen, deuterium, or a combination thereof. The atomic orbital based data storage that can be rewritten and corrected as needed. The resulting data storage is also archival and capable of high data densities than any known storage as the data is retained in a binary storage or a given orbital being passivated or a dangling bond (DB). A method of forming and reading the atomic orbital data storage is also provided. The method including selectively removing covalent bonds to form dangling bonds (DBs) extending from a surface atom by hydrogen lithography and imaging the covalent bonds spatially to read the atomic orbital data storage.Type: GrantFiled: June 19, 2019Date of Patent: January 17, 2023Assignees: National Research Council of Canada, Quantum Silicon Inc., The Governors of the University of AlbertaInventors: Roshan Achal, Robert A. Wolkow, Jason Pitters, Martin Cloutier, Mohammad Rashidi, Marco Taucer, Taleana Huff
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Patent number: 11545633Abstract: The development of air-stable unipolar n-type semiconductors with good solubility in organic solvents at room temperature remains a critical issue in the field of organic electronics. Moreover, most of the existing semiconducting materials exhibit LUMO energy levels higher than ?4.0 eV, making electron transport sensitive to both moisture and oxygen. Bis(2-oxoindolin-3-ylidene)benzodifurandione dicyanide or derivatives thereof are disclosed herein. More specifically, bis(2-oxoindolin-3-ylidene)benzodifurandione dicyanide or derivatives thereof for use in organic electronics are disclosed. A process for the preparation of bis(2-oxoindolin-3-ylidene)benzodifurandione dicyanide and derivatives is also disclosed. The bis(2-oxoindolin-3-ylidene)benzodifurandione dicyanide or derivatives thereof are characterized by high electron mobilities and are suitable for use as n-type semiconductors in organic electronics.Type: GrantFiled: March 13, 2019Date of Patent: January 3, 2023Assignees: NATIONAL RESEARCH COUNCIL OF CANADAInventors: Jianping Lu, Afshin Dadvand, Mark Bortolus, Salima Alem, Ye Tao, Yuning Li, Jesse Quinn
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Patent number: 11525066Abstract: A flake-less molecular ink suitable for printing (e.g. screen printing) conductive traces on a substrate has 30-60 wt % of a C8-C12 silver carboxylate and 0.1-10 wt % of a polymeric binder, or 5-75 wt % of bis(2-ethyl-1-hexylamine) copper (II) formate, bis(octylamine) copper (II) formate or tris(octylamine) copper (II) formate and 0.25-10 wt % of a polymeric binder, and balance of at least one organic solvent, wherein the binder has ethyl cellulose, and the ethyl cellulose has an average weight molecular weight in a range of 60,000-95,000 g/mol and a bimodal molecular weight distribution.Type: GrantFiled: November 24, 2020Date of Patent: December 13, 2022Assignees: National Research Council of Canada, Groupe Graham International Inc.Inventors: Arnold J. Kell, Sylvie Lafrenière, Chantal Paquet, Patrick Malenfant, Olga Mozenson