Abstract: The present disclosure relates to an artificial ankle joint tibial component and, more particularly, to an artificial ankle joint tibial component of an implant that is implanted into a body, the implant including: a body part having a contact surface in contact with a resected surface of a distal end of a tibia of a joint and a joint surface facing a joint; and a fixing part formed to extend a predetermined length upwards from the contact surface, wherein the fixing part is configured as a single body formed to extent a predetermined length upwards from the center in the front area of the contact surface and includes a wing extending to one side, and wherein the wing includes at least one posterior wing that extends at a predetermined angle relative to an AP line, thereby preventing stress from being concentrated on one wing to avoid a fracture thereof and increasing the contact area between a bone and an implant to strengthen fixing force, prevent rotation, and disperse stress, so that bone resorption aroun

Abstract: New uses of Cyclo-HisPro (CHP) or a salt thereof for lowering blood pressure are disclosed. More specifically, the present invention relates to a pharmaceutical composition for lowering blood pressure, containing CHP or a salt thereof, and a functional health food composition containing CHP or a salt thereof; a method for lowering blood pressure using CHP or a salt thereof; a use of CHP or a salt thereof in the manufacture of antihypertensive agents; a pharmaceutical composition or a functional health food, for preventing or treating hypertension or complications thereof, containing CHP or a salt thereof; a method for preventing or treating hypertension or complications thereof by using CHP or a salt thereof; and a use of CHP or a salt thereof in the manufacture of a medicament for preventing or treating hypertension or complications thereof.

Abstract: The present invention relates to a pharmaceutical composition and the like for lowering blood cholesterol, preventing or treating cardiovascular diseases and reducing inflammation, containing, as an active ingredient, an inhibitor of binding between CAP1 and PCSK9, an inhibitor of binding between CAP1 and resistin, or a CAP1 gene expression inhibitor. The present invention can lower the level of blood LDL-cholesterol by inhibiting the binding of CAP1 and PCSK9, the binding of CAP1 and resistin or the expression of a CAP1 gene. Therefore, the present invention can be effectively used as a pharmaceutical composition and the like for treating abnormal blood cholesterol levels and various cardiovascular diseases caused thereby, such as dyslipidemia, stroke, arteriosclerosis, and the like, and for inhibiting inflammation.

Abstract: A sinus entering endoscope according to an embodiment of the present invention comprises: a body including a plurality of operation parts; an insertion part extending from the front end of the body to be inserted into the sinus through the nasal cavity, and having at least one working channel; and an applicator load part which is disposed in the body and on which a plurality of applicators which can selectively enter through the working channel can be mounted.

Abstract: A system for monitoring a volume of a bladder during a surgical procedure. The system includes one or more processors; and a memory that is communicatively coupled to the one or more processors and stores one or more sequences of instructions, which when executed by one or more processors causes steps to be performed comprising: receiving information of a maximum volume of the bladder before the surgical procedure; receiving one or more ultrasound images from an ultrasonic scanner; based on the one or more ultrasound images, determining a volume of the bladder; comparing a maximum volume of the bladder to the determined volume of the bladder; and responsive to a difference between the maximum volume and determine volume of the bladder exceeding a threshold, issuing a warning associated with the difference.

Abstract: An apparatus for imaging examination of cells on a surface of living tissue using moxifloxacin includes: a light source emitting light towards living tissue stained with moxifloxacin; a photographing unit photographing the living tissue subjected to fluorescence excitation by the light emitted from the light source; a lens unit controlling the light emitted from the light source or a fluorescence path of moxifloxacin excited by the light; an objective lens controlling a focus of the photographing unit; an active lens disposed between the objective lens and the photographing unit and changing a focal position on the living tissue; and an image generator performing image processing of a cell image of the living tissue photographed by the photographing unit to generate an in-focus image, in which the entirety of the cell image is in focus.

Abstract: There is provided a method of providing information about prognosis after cardiac arrest. The method includes the steps of: calculating biological information based on a signal relating to a hemoglobin concentration measured from a cerebral region of a subject to be measured; and providing the information about the prognosis after cardiac arrest of the subject with reference to the calculated biological information and a biomarker relating to the prognosis after cardiac arrest measured from a blood of the subject.

Abstract: The present disclosure relates to a novel compound or a salt thereof, a composition for detecting cysteine, a fluorescent probe, and a composition for diagnosing cancer, which contain the same, a method for detecting cysteine, a method for providing information for diagnosing cancer, and a method for producing the novel compound. According to the present disclosure, there may be provided a method of synthesizing and purifying a fluorescent probe for cysteine detection and applying the same to diagnose cervical cancer by detecting cysteine in human urine.

Abstract: Disclosed is a dip-coating method as a method of coating an outer surface of a target mold including steps of: preparing and putting a supporting liquid in a container; applying a coating material to the target mold; dipping the target mold in the supporting liquid; shaking the target mold surrounded by the coating material in the supporting liquid; curing the coating material surrounding the target mold in the supporting liquid; and taking out the coated target mold from the supporting liquid.

Abstract: Disclosed are an artificial prosthesis and a method for manufacturing same. The artificial prosthesis includes a surface having a pattern formed thereon, the pattern comprising straight line shapes aligned in parallel with each other, and has the effect of reducing inflammation in a region implanted with the prosthesis, and effectively reducing capsular contracture side effects.

Abstract: There is provided a material comprising a multi-block thermogelling polymer, said multi-block thermogelling polymer comprising a hydrophilic polymer block; a thermosensitive polymer block; and a hydrophobic polymer block, wherein the hydrophilic polymer block, the thermosensitive polymer block and the hydrophobic polymer block are chemically coupled together by at least one of urethane/carbamate, carbonate, ester linkages or combinations thereof, and wherein the material is suitable for use as a vitreous substitute. Also provided are a method of preparing said material and a synthetic vitreous humour or part thereof comprising said material.

Abstract: Provided are a composition for treating or preventing recurrence of keloid comprising tauroursodeoxycholic acid as an active ingredient, and a method for treating keloid or preventing recurrence of keloid using the composition.

Abstract: A method for manufacturing a personalized naturally designed mitral valve prosthesis to precisely fit a specific patient for which the valve prosthesis is made for is provided. The method includes measuring size and shape of a mitral valve of the specific patient by using imaging methods, calculating geometry and dimensions of annular ring, leaflets and chords per the specific patient based on validated algorithms, and cutting and connecting the annular ring, leaflets and chords to form a personalized prosthesis mitral valve.

Abstract: Some embodiments of the present disclosure provide a pneumothorax detection method performed by a computing device. The method may comprise obtaining predicted pneumothorax information, predicted tube information, and a predicted spinal baseline with respect to an input image from a trained pneumothorax prediction model; determining at least one pneumothorax representative position for the predicted pneumothorax information and at least one tube representative position for the predicted tube information, in a prediction image in which the predicted pneumothorax information and the predicted tube information are displayed; dividing the prediction image into a first region and a second region by the predicted spinal baseline; and determining a region in which the at least one pneumothorax representative position and the at least one tube representative position exist among the first region and the second region.

Abstract: Provided is a method of operating an apparatus for prostate cancer analysis operated by at least one processor, the method including: receiving digital slide images prepared from serial sections of a prostatectomy specimen, and a gross image of the serial sections; acquiring prostate cancer-related histological information of each received digital slide image using an artificial neural network model trained to infer histological information from the digital slide images; generating digital pathology images by displaying the prostate cancer-related histological information inferred from the artificial neural network model on each digital slide image; and providing a histological mapping image in which a tumor region extracted from each digital pathology image is mapped to a gross image of the corresponding section.

Abstract: The bioenvironmental simulation device according to an embodiment of the present invention includes at least one mounting unit on which cells to be measured are placed, a rotational force application unit configured to rotate the mounting unit so as to apply a rotational force to the cells to be measured placed on the mounting unit, and a culture liquid flow device through which a culture liquid flows across the mounting unit, wherein the culture liquid flows by the culture liquid flow device so as to apply a shear force to the cells to be measured.

Abstract: An intervertebral fusion cage is disclosed. An intervertebral fusion cage according to an embodiment of the present invention comprises: a body including a receiving part of which upper and lower portions are open, an upper guide part, and a lower guide part; a moving member disposed in the receiving part; a screw which is screw-coupled to the body and moves forwards or backwards relative to the body integrally with the moving member when rotating; an upper plate which has a guided part guided by the upper guide part and is disposed above the body while being engaged with the moving member; and a lower plate which has a guided part guided by the lower guide part and is disposed under the body while being engaged with the moving member.

Abstract: A DNA analysis method and a DNA analyzing device using terahertz wave capable of accurately determining a type of cancer from DNA using terahertz wave are disclosed. The DNA analysis method according to the present invention comprises: (a) irradiating terahertz wave onto methylated DNA; (b) detecting the terahertz wave reflected from the methylated DNA; (c) detecting a peak of a waveform of the terahertz wave detected in the step (b); and (d) determining type of cancer from the peak detected in the step (c).

Abstract: A surgical polygonal locking screw removal device includes: a body including a passage part in which a passage having a preset diameter is formed, and a polygonal expansion part configured to be coupled to a polygonal groove formed in a surgical locking screw to remove the surgical locking screw, the polygonal expansion part protruding from a leading end of the passage part; and a handle configured to be inserted into a rear end of the passage part and screw-coupled to the passage part, and configured to expand the polygonal expansion part.