Patents Assigned to National University Hospital
  • Patent number: 10722202
    Abstract: The present invention comprises: a first X-ray irradiation apparatus and a second X-ray irradiation apparatus for irradiating a subject with X-rays; an X-ray generation unit supporting so that first and second X-rays irradiated onto the subject are detected by a set detector when the subject is irradiated with the first and second X-rays from the first and second X-ray irradiation apparatuses, respectively; and a mode selection unit for allowing selection of any one mode from among a 2D imaging mode and 3D imaging mode, wherein the angles with respect to the subject of the first and second X-ray irradiation apparatuses are determined on the basis of said any one mode selected by means of the mode selection unit from among the 2D imaging mode and 3D imaging mode. According to the present invention, the mode can be easily selected according to need from among the 2D imaging mode and 3D imaging mode.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: July 28, 2020
    Assignee: Seoul National University Hospital
    Inventors: Chang Hwan Yoon, Dong Hoon Han
  • Patent number: 10702637
    Abstract: The present invention relates to a guiding needle for a suction tube, which is for increasing accuracy and preventing medical accidents by enabling an operator to accurately recognize the bent direction of the needle and to stably hold the needle by means of a handle portion formed inside the rear end of the needle connected to a tube or by means of a separate fixing handle coupled to the inside of the rear end of the needle. In other words, the present invention relates to a needle having the rear end thereof coupled to one end of a tube connected to a drainage container for discharging body blood of a patient, wherein the needle has a coupling part formed inside the rear end thereof and comprises a fixing handle detachably coupled to the coupling part.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: July 7, 2020
    Assignees: INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY, CHONBUK NATIONAL UNIVERSITY HOSPITAL, SUNGWON MEDICAL CO., LTD.
    Inventors: Jong Kwan Park, Jun Sung Park
  • Patent number: 10687896
    Abstract: A method for surgical resection planning of a mass includes the steps of, modelling the mass based on a plurality of physical dimensions, determining a plurality of safety margins around a plurality of features within the mass, simulating a resection surface on the mass that includes a plurality of triangles, optimizing local area and position of a first of the plurality of triangles on the resection surface based on a triangle-based algorithm, updating the simulation of the resection surface, and repeating the steps of optimizing and updating for each of the plurality of triangles on the resection surface.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: June 23, 2020
    Assignees: Agency for Science, Technology and Research, National University Hospital (Singapore) Pte Ltd.
    Inventors: Wenyu Chen, Sudhakar K. Venkatesh, Qi Tian, Jianyin Zhou, Weimin Huang, Wei Xiong, Oo Thiha
  • Patent number: 10692397
    Abstract: A smart nasometer according to an embodiment of the present invention includes: a hardware unit worn on a head of a user for measuring nasal and oral sounds and providing feedback for the user; and a computational unit for receiving and processing speech signals of the nasal and oral sounds measured by the hardware unit, wherein the hardware unit includes: a microphone unit for separately measuring the nasal and oral sounds in a non-touched state of the user's philtrum, wherein the computational unit includes: a nasalance adjustment unit for adjusting a nasalance of the nasal and oral sounds measured by the microphone unit.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: June 23, 2020
    Assignees: POSTECH ACADEMY-INDUSTRY FOUNDATION, INDUSTRIAL COOPERATION FOUNDATION OF CHONBUK NATIONAL UNIVERSITY, CHONBUK NATIONAL UNIVERSITY HOSPITAL
    Inventors: Heecheon You, Myoung-Hwan Ko, Jong-Kwan Park, Younggeun Choi, Hyun Gi Kim, Han Soo Lee, Gradiyan Budi Pratama, Min-Jung Yu, Ki Wook Kim, Yun Ju Jo, Jin Kook Lee
  • Patent number: 10682054
    Abstract: The present disclosure relates to an apparatus for angiographic optical coherence tomography in the retina or the choroid, and a method for diagnosing diseases by using the same and, more specifically, to: an apparatus for angiographic optical coherence tomography in the retina and the choroid, capable of diagnosing, at an early stage, shock states or diseases such as those of sepsis by quickly and objectively recognizing the low perfusion of tissue; and a diagnostic method using the same.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: June 16, 2020
    Assignees: SEOUL NATIONAL UNIVERSITY HOSPITAL, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Wangyuhl Oh, Jang Ryul Park, Kyuseok Kim
  • Patent number: 10674924
    Abstract: Systems and methods for mapping a cavernous nerve near an organ. The system includes: one or more processors; and a memory that is communicatively coupled to the one or more processors and stores one or more sequences of instructions, which when executed by one or more processors causes steps to be performed comprising: applying an excitation signal to an electrode at a tip of an laparoscope, the tip being configured to contact a point on a tissue near an organ; responsive to the excitation signal, measuring a change in a signal from a pair of electrodes configured to be installed on the penis, the change in the signal being associated with an erectile function of the penis; and based on the change in the signal from the pair of electrodes, determining a distance between the point on the tissue and a cavernous nerve near the organ.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: June 9, 2020
    Assignee: SEOUL NATIONAL UNIVERSITY HOSPITAL
    Inventors: Chang Wook Jeong, Keewon Kim
  • Patent number: 10662407
    Abstract: The present disclosure relates to a method for controlling the differentiation of embryonic stem cells into adipocytes or kidney precursor cells by regulating SIRT1 (silent mating type information regulation 2 homolog; sirtuin 1) expression, the method, which controls the differentiation of embryonic stem cells into adipocytes by regulating SIRT1 expression, being capable of controlling the inhibition or promotion of adipocyte differentiation in accordance with the timing of a SIRT1 expression inhibitor treatment. Furthermore, kidney precursor cell differentiation can be regulated by a SIRT1 expression inhibitor or promoter treatment. Accordingly, a SIRT1 inhibitor can be selected to be used as an inhibitor or a therapeutic agent for obesity, diabetes accompanying obesity, and renal and metabolic diseases.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: May 26, 2020
    Assignees: INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY, Chonbuk National University Hospital
    Inventors: Won Kim, Yu Jin Jung
  • Publication number: 20200126665
    Abstract: Provided are a device, a method, and a computer program for self-diagnosis and treatment of benign paroxysmal positional vertigo, which is for, when a patient with benign paroxysmal positional vertigo develops or appeals symptoms, immediately, easily and accurately diagnosing the symptoms by patients themselves using a sequential and efficient self-diagnosis algorithm associated with an optimized self-diagnosis questionnaire data without temporal or spatial constraints, and presenting an optimal treatment method, so as to allow the patients to receive appropriate on-site treatments. The present disclosure is effective in not only immediate treatment of benign paroxysmal positional vertigo, but also reducing medical expenses and additional social costs incurred for treatments of dizziness.
    Type: Application
    Filed: October 25, 2019
    Publication date: April 23, 2020
    Applicant: SEOUL NATIONAL UNIVERSITY HOSPITAL
    Inventors: Ji-Soo Kim, Hyo-Jung Kim
  • Patent number: 10611720
    Abstract: Provided are a compound represented by the following Formula I, or a solvate, stereoisomer, or pharmaceutically acceptable salt thereof, and a composition for preventing or treating hair loss, the compound including the compound as an active ingredient:
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: April 7, 2020
    Assignees: UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY), Seoul National University Hospital
    Inventors: Mi Hee Lim, Sang Tae Kim, Ho Seong Han
  • Publication number: 20200101217
    Abstract: An enema device for washing a large intestine that can supply water to a large intestine to easily wash and defecate the large intestine. The enema device for washing a large intestine includes a nozzle part inserted into an anal passage and having an ejection hole for ejecting water at one end thereof; a balloon part coupled to an outer peripheral surface of the nozzle part to be expanded; an air pump configured to supply air to the balloon part; a switching valve, to which the air pump is connected; a first water hose, an air hose, and a second water hose; the nozzle part has a discharge hole through which air supplied from the air hose is discharged to the balloon part.
    Type: Application
    Filed: May 15, 2018
    Publication date: April 2, 2020
    Applicant: CHONBUK NATIONAL UNIVERSITY HOSPITAL
    Inventors: Jeong Hwan SEO, Myoung Hwan KO, Kap Soo HAN
  • Publication number: 20200100657
    Abstract: A protection cover for a nose endoscopy, and more particularly to a protection cover for a nose endoscopy that can prevent discharges generated during sneezing in a nose endoscopy from being ejected to a healthcare provider. The protection cover for a nose endoscopy includes: a fixed member coupled to the head of a wearer; and a main cover coupled to a lower portion of the fixed member and configured to cover a front surface of the face of the wearer, A through-hole for exposing the nostrils of the wearer to the outside is formed in the main cover.
    Type: Application
    Filed: May 15, 2018
    Publication date: April 2, 2020
    Applicant: CHONBUK NATIONAL UNIVERSITY HOSPITAL
    Inventors: Sang Kyi LEE, Myoung Hwan KO, Kap Soo HAN
  • Publication number: 20200100735
    Abstract: An upright posture assisting device for an X-ray inspection of infants, and more particularly to an upright posture assisting device for an X-ray inspection of infants, by which an infant can be X-ray photographed while being safely fixed. The upright posture assisting device for an X-ray inspection of infants includes: a body disposed on the front side of an X-ray detector and having an empty space in the interior thereof; an insertion hole formed on the upper surface of the body such that the legs of an infant are inserted into the insertion hole; and handgrip parts mounted on opposite sides of the upper surface of the body.
    Type: Application
    Filed: May 15, 2018
    Publication date: April 2, 2020
    Applicant: CHONBUK NATIONAL UNIVERSITY HOSPITAL
    Inventors: Ho Tae LIM, Myoung Hwan KO, Kap Soo HAN
  • Patent number: 10597362
    Abstract: The present invention relates to a compound represented by Chemical Formula 1, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of cardiovascular diseases.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: March 24, 2020
    Assignee: Seoul National University Hospital
    Inventors: Ja Kyung Yoo, Nora Lee, Chun Ho Lee, Hyo-Soo Kim
  • Patent number: 10588906
    Abstract: Provided herein is a method of preventing hair loss or promoting hair growth, the method including administering an effective amount of a PDE 3 inhibitor. More particularly, when the method of the present disclosure is used, an excellent hair loss prevention or hair growth promotion effect is obtained by inhibiting the activity of PDE 3.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: March 17, 2020
    Assignee: SEOUL NATIONAL UNIVERSITY HOSPITAL
    Inventors: Ohsang Kwon, Hye-In Choi, Seong Jin Jo, Kyu Han Kim
  • Patent number: 10577609
    Abstract: The present invention relates to a DNA aptamer specifically binding to a hepatocellular carcinoma-related Glypican-3 (GPC3) protein, treatment of cancers related to the Glypican-3 protein using the same, a composition for inhibiting a cancer and a composition for diagnosing a cancer comprising the same as an active ingredient.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: March 3, 2020
    Assignees: POSTECH ACADEMY—INDUSTRY FOUNDATION, SEOUL NATIONAL UNIVERSITY HOSPITAL, YONSEI UNIVERSITY, UNIVERSITY—INDUSTRY FOUNDATION (UIF)
    Inventors: Eun Ju Oh, Jung Hwan Lee, Jong-Hoon Lim, Jong In Kim, Jung Hwan Yoon, Sung Ho Ryu, Jeong-Hoon Lee, Won Jun Kang, Seong Hui Jin
  • Publication number: 20200064258
    Abstract: A DNA analysis method and a DNA analyzing device using terahertz wave capable of accurately determining a type of cancer from DNA using terahertz wave are disclosed. The DNA analysis method according to the present invention comprises: (a) irradiating terahertz wave onto methylated DNA; (b) detecting the terahertz wave reflected from the methylated DNA; (c) detecting a peak of a waveform of the terahertz wave detected in the step (b); and (d) determining type of cancer from the peak detected in the step (c).
    Type: Application
    Filed: November 16, 2017
    Publication date: February 27, 2020
    Applicants: UNIVERSITY OF SEOUL INDUSTRY COOPERATION FOUNDATION, SEOUL NATIONAL UNIVERSITY HOSPITAL
    Inventors: Joohiuk SON, Hwayeong CHEON, Heejin YANG
  • Patent number: 10570370
    Abstract: Provided are a method of preparing retinal ganglion cells by differentiation of stem into retinal ganglion cells, retinal ganglion cells differentiated by the method, a method of screening for a death inhibitor or a proliferation promoter of retinal ganglion cells using the retinal ganglion cells differentiated by the method, a kit of screening for the death inhibitor or the proliferation promoter of retinal ganglion cells including the retinal ganglion cells differentiated by the method, a pharmaceutical composition for treating glaucoma or optic neuropathy including the retinal ganglion cells, a method of treating glaucoma or optic neuropathy including the step of administering the retinal ganglion cells to a subject suspected of having glaucoma or optic neuropathy, and a method of preparing a mature retinal ganglion cell line.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: February 25, 2020
    Assignees: Seoul National University R&DB Foundation, Seoul National University Hospital
    Inventors: Sung Sup Park, Ji Yeon Kim
  • Patent number: 10500094
    Abstract: Systems, devices, and methods for treating a glaucomatous eye are provided. Embodiments may provide a treatment probe for treating an eye of a patient. The treatment probe may have an elongate body with a contact surface at a distal end of the elongate body. A treatment fiber or light source may be housed in the treatment probe and may be configured to direct treatment energy from the contact surface. The contact surface may be configured to couple to a surface of the eye to deliver the energy into the target area. In many embodiments the contact surface may have a convex configuration with a rounded outer shape and edge that facilitates the sweeping of the probe surface across the eye during treatment delivery. In some embodiments the probe may be swept in arc motions while delivering treatment energy to the eye.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: December 10, 2019
    Assignees: IRIDEX Corporation, National University Hospital (Singapore) PTE LTD, National University of Singapore
    Inventors: David Buzawa, Paul T. K. Chew
  • Patent number: 10464901
    Abstract: Provided are a compound represented by the following Formula I-1 or I-2, and a composition for preventing or treating dementia or Alzheimer's disease, the composition including the compound and a pharmaceutically acceptable carrier:
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: November 5, 2019
    Assignees: UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY), SEOUL NATIONAL UNIVERSITY HOSPITAL
    Inventors: Mi Hee Lim, Sang Tae Kim, Ho Seong Han
  • Patent number: 10401505
    Abstract: The present disclosure relates to a contact lens type dosimeter for measuring a dose distribution of a crystalline lens during radiation therapy, and a method of manufacturing the same. The ocular dosimeter has a contact lens shape and is configured to be worn on an eyeball, which comprises a basic material containing hydrophilic polyurethane, and a radiochromic dye. When the ocular dosimeter is worn on the eyeball, the dosimeter is configured to measure a radiation dose irradiated to a crystalline lens through a variation in color of the ocular dosimeter.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: September 3, 2019
    Assignee: SEOUL NATIONAL UNIVERSITY HOSPITAL
    Inventors: Jung In Kim, Jong Min Park, Won Mo Sung, Hong Gyun Wu