Abstract: A nutritional composition promotes musculoskeletal health in patients with inflammatory bowel disease. The nutritional composition contains casein protein, vitamin D, alpha-linolenic acid, and vitamin K in a ratio of vitamin K1:vitamin K2 between 3:1 to 1:3 and the vitamin K providing between 3.5-20 ?g/100 cal of the nutritional composition. A pharmaceutical formulation, a nutritional formulation, a tube-feed formulation, a dietary supplement, a functional food, a beverage product or a combination thereof comprising the nutritional composition is also disclosed. A method for improving musculoskeletal health is also disclosed.

Abstract: The inventions discloses a composition comprising at least one N-acetyl lactosamine, at least one sialylated oligosaccharide and at least one fucosylated oligosaccharide, for use in preventing acute respiratory infections (ARI) and/or relieving symptoms of said ARI infections. Preferably said composition is a starter infant formula. Said acute respiratory infection is in particular bronchiolitis or otitis.

Abstract: The present invention concerns a beverage dispensing system for providing a multi-layered beverage is disclosed. The beverage dispensing system is adapted to prepare a plurality of beverages of different densities within a plurality of ingredients container. The beverage dispensing system separately and sequentially dispenses a lower density beverage prior to dispensing a higher density beverage. The beverages are dispensed via a delivery tube which is disposed proximally to an internal base of a drinks receptacle. Furthermore an ingredients container is disclosed. Furthermore a method for the manufacture of the multi-layered beverage is disclosed.

Abstract: The present invention provides methods for predicting whether an individual having inflammatory bowel disease (IBD) is likely to respond to vedolizumab treatment. Also provided are methods for predicting whether an individual with IBD such as Crohn's disease or ulcerative colitis will develop autoantibodies against vedolizumab. The present invention also provides a treatment regimen for an IBD patient which includes measuring the level of one or more predictive markers of response to vedolizumab prior to administering the anti-?4?7 integrin drug.

Abstract: Apparatuses for performing consumer testing and methods for using same are provided. Methods for administering consumer research are also provided. In a general embodiment, the present disclosure provides apparatuses having a rotatable platform with at least one divider separating the platform into at least two sections, where each of the at least two sections includes a life-like scenario configured for use by a consumer participant during a consumer research test. Such apparatuses provide flexibility and efficiency of time, space and cost for performing consumer research since the research may be performed in a timely fashion, in a number of different life-like scenarios, in a limited amount of space, and may be directly observed from one location or using one set of audio/visual equipment.

Abstract: A system comprises a cartridge (9) containing a beverage ingredient and a device (1) for brewing the ingredient in the cartridge by supplying a brewing liquid such as heated water into the cartridge. The device has upstream and downstream cartridge enclosing parts (7, 8) relatively movable between an open position for inserting and/or removing the cartridge and a closed position for forming a brewing chamber (11) enclosing the cartridge during brewing. The brewing chamber (11) has a confining expansion space (12) which is: unoccupied by the cartridge (9) when the enclosing parts (7, 8) are in the closed position enclosing the cartridge; and occupied by the cartridge upon expansion thereof caused by exposure of the ingredient to the brewing liquid.

Abstract: The invention proposes a device for preparing a beverage from a food substance contained in a capsule (24) by injection of a liquid into the capsule (24), wherein said liquid is provided by a pump (70) of the device, said device comprising an extraction head (20) having an aperture (22) for inserting a capsule-holder (30) providing the capsule (24) to a capsule-holder receiving chamber (25) of the device, a closing mechanism (21) to selectively enclose said capsule (24) in the capsule-holder receiving chamber (25), at least one injection member (11) to supply a liquid received from the pump (70) to the inside of the capsule (24), a control unit (80) for controlling at least the pump (70) of the device, and decoding means (1) connected to the control unit (80) and designed to read information from the capsule-holder (30).

Abstract: A method and system for preparing a beverage or liquid from a food substance contained in a filtering receptacle by passing water through the substance using brewing centrifugal forces. The method includes feeding water into the receptacle, and driving the receptacle in centrifugal rotation to force water to flow through the substance in a centrifugal flow path to the outlet of the receptacle. The system includes equipment necessary to carry out the method. The receptacle is a sealed capsule which is opened for water to be introduced into the capsule, contains a predetermined dose of food substance and is discarded after use.

Abstract: The invention concerns a process for the preparation of a beverage in a beverage machine with a capsule comprising an enclosure containing tea leaves comprising the steps of: a) introducing water in the capsule to submerge the tea leaves in the capsule enclosure, then b) letting the tea leaves soak, then c) introducing water in the capsule until the required volume of beverage is delivered, wherein water is continuously introduced in the capsule from the beginning of step a) until the end of step b).

Abstract: The invention proposes a device for preparing a beverage from a food substance contained in a capsule (24) by injection of a liquid into the capsule (24), wherein said liquid is provided by a pump (70) of the device, said device comprising an extraction head (20) having an aperture (22) for inserting a capsule-holder (30) providing the capsule (24) to a capsule-holder receiving chamber (25) of the device, a closing mechanism (21) to selectively enclose said capsule (24) in the capsule-holder receiving chamber (25), at least one injection member (11) to supply a liquid received from the pump (70) to the inside of the capsule (24), a control unit (80) for controlling at least the pump (70) of the device, and decoding means (1) connected to the control unit (80) and designed to read information from the capsule-holder (30).

Abstract: Oral engagement assemblies and methods of using the oral engagement assemblies are provided. In a general aspect, the oral engagement assembly includes a mouthpiece having a handle and a support attached to the handle. A diagnostic receptacle is insertable into the mouth-piece to form the oral engagement assembly. One or more diagnostic sensors can be fixedly or releasably inserted into the diagnostic receptacle. Kits useful for making the oral engagement assemblies and using such oral engagement assemblies for diagnosing a condition or disease in the animal are also provided.

Abstract: The invention relates to a double-cone pumping device, designed to provide for flow of the liquid product only on the outer side of the rotating cones, making it compatible with mixing of particulate-containing liquid products; and specifically advanced for high pumping capacity in mixing-agitation applications in food processing. The double-cone pumping device comprises two cones that are axially symmetrically arranged with their large bases abutting, and rotatable around the axis, and an axial shaft that connects to driving means. The invention also relates to a use of this pump in processing of liquid food.

Abstract: Beverage capsule for preparing a beverage in a beverage preparation device from a capsule containing beverage ingredients by passing water through the ingredients contained in the capsule using centrifugal forces, said device comprising means for driving the capsule in rotation around an axis of rotation (I), a capsule holder for receiving the capsule and a water injection means for injecting water in the capsule, said device further comprising a valve means for engaging a valve engaging portion of the capsule; said valve means comprising a pressing ring; the capsule comprising a body and a lid and a valve engaging portion designed for being inserted between the capsule holder and the valve means of the device; wherein said capsule comprises an outlet structure forming beverage flow restriction passages of defined cross-section in the capsule at such and/or as a result of the insertion of the valve engaging portion between the capsule holder and the pressing ring of the valve means.

Abstract: Capsule (9) for use in a beverage preparation machine (1), said capsule comprising side (10), bottom (12) and top (11) walls defining a closed chamber, said capsule further comprising a beverage dispensing wall able to open for releasing a beverage prepared from said ingredient and said fluid, said capsule comprising a separating wall (14) within the chamber that separates, in a leak-tight manner, an ingredient-containing compartment (15), and a fluid injection compartment (16), said separating wall (14) comprising a one-way valve (17) able to let fluid under pressure flow only from the injection compartment towards the ingredient-containing compartment, said valve being actuated in its open configuration by the injection element (22) of the machine, wherein the one-way valve is either: (i) a spring-mounted ball valve, or alternatively (ii) a flexible resilient O-ring valve mounted in a circular channel of the separating wall.

Abstract: Heat exchange devices (30) and methods of using same are provided. In a general embodiment, the present disclosure provides for heat exchange devices (30) that are cooling devices having a double helical coil (32) in a phase-mixing-cooling section, a helical coil (36) in a phase-separation-cooling section, and a back-pressure valve (34) intermediate the two coils (32,36). The cooling devices provide maximum extraction of the heat content from a heated food product using a direct-injected liquid cryogen, and complete separation of the gaseous cryogen phase from the cooled product, while avoiding the formation of a stable foam. Hybrid direct-indirect cooling devices are also provided, as well as methods for using same.

Abstract: The present invention provides antibodies and methods for preparing antibodies to metabolites in the serotonin, tryptophan and kynurenine pathways, such as 5-hydroxyindole-3-acetic acid (5-HIAA), melatonin (MT) and kynurenic acid (KYNA). The specific metabolite antibodies have low cross-reactivity to structurally related metabolites, and are useful reagents for specific and sensitive immunoassays. The present invention also provides methods for using such antibodies to measure the levels of 5-HIAA, melatonin, or kynurenic acid in biological samples from human patients.

Abstract: The present invention relates to a bakery product comprising a salty tastant. In particular the invention relates to a bakery product having a powder applied to at least one surface, the powder particles comprising a starch-based material and a salty tastant. A further aspect of the invention is a process for manufacturing a bakery product.

Abstract: The present invention provides methods for aiding in the diagnosis of irritable bowel syndrome (IBS) in an individual. In particular, the present invention is useful for determining whether the individual does not have either celiac disease or inflammatory bowel disease (IBD), and has IBS and/or a subtype thereof. Thus, the present invention provides an accurate diagnostic prediction of IBS and is useful for guiding treatment decisions.

Abstract: The present invention relates to a bakery product. In particular the invention relates to a bakery product comprising dough and a filling or topping wherein the bakery product has an exposed dough surface having a coating comprising sodium chloride. A further aspect of the invention is a process for manufacturing a bakery product.

Abstract: The present invention relates to synthetic nutritional compositions, especially infant formula compositions, with a low content of medium-chain fatty acids (or MFCAs) and particularly in specific proportions. The invention also relates to the use of said compositions to promote liver and/or gut maturation in infants or young children and/or to reduce the risk of liver and/or gut disease in infants or young children.