Abstract: This invention provides, among other things, compounds useful for treating spirochete diseases such as Lyme disease, as well as pharmaceutical formulations and/or environmental baits containing such compounds.

Abstract: Devices and methods for detecting an analyte in a gas involve the use of plasmonic excitation of a nanostructured sensing element that is tuned to absorb at a narrow bandwidth specific for light absorbed by the analyte. The sensing element can be used as a capacitive or inductive element in a circuit.

Abstract: Provided is a fault signal locating and identifying method of industrial equipment based on a microphone array. The method includes the steps of: acquiring sound signals and dividing the acquired signals into a training set, a verifying set and a test set; performing feature extraction on the sound signals in the training set, and extracting a phase spectrogram and an amplitude spectrogram of a spectrogram; sending an output of a feature extraction module, as an input, to a CNN, and in each layer of the CNN, learning a translation invariance in the spectrogram by using a 2D CNN; in between the layers of the CNN, normalizing the output by using a batch normalization, and reducing a dimension by using a maximum pooling layer along a frequency axis; sending an output from the layers of the CNN to layers of RNN; using a linear activation function; and inputting an output of a full connection layer to two parallel full connection layer branches for fault identification and fault location, respectively.

Abstract: Provided herein are systems and methods for estimating contact pressure of a human lying on a surface including one or more imaging devices having imaging sensors oriented toward the surface, a processor and memory, including a trained model for estimating human contact pressure trained with a dataset including a plurality of human lying poses including images generated from at least one of a plurality of imaging modalities including at least one of a red-green-blue modality, a long wavelength infrared modality, a depth modality, or a pressure map modality, wherein the processor can receive one or more images from the imaging devices of the human lying on the surface and a source of one or more physical parameters of the human to determine a pressure map of the human based on the one or more images and the one or more physical parameters.

Abstract: Provided herein are systems for controlling a network of distributed non-terrestrial nodes including a control framework operative to train and control a plurality of the non-terrestrial nodes, the control framework including a control interface in communication with a network operator to receive one or more specified control objectives, and a learning engine operative to train a virtual non-terrestrial network, wherein the control framework is further operative to transfer knowledge gained through the training of the virtual non-terrestrial network to the network of distributed non-terrestrial nodes as data-driven logic unit configurations tailored for the specified control objectives.

Abstract: Methods and systems are provided for controlling an unmanned aerial vehicle (UAV) swarm network including receiving, at a control terminal, an operator input defining a plurality of network performance directives, constructing a network control model representing the plurality of network performance directives, decomposing the network control model into a plurality of sub-models, generating, via the control terminal, a distributed UAV control model corresponding to each of the distributed sub-models, transmitting the generated distributed UAV control models to each of a plurality of UAVs of the UAV swarm network, executing, at each of the plurality of UAVs, at least one of the distributed UAV control models, and changing, responsive to the execution of the distributed UAV control models, an operating condition of at least one of the plurality of UAVs to satisfy the network performance directives.

Abstract: A method and a device for measuring a temperature of a wire rod, a storage medium, and a computer device are disclosed. The method includes: determining an effective temperature measurement area according to the infrared thermal image and feature information of the wire rod; projecting preset light onto the wire rod geometric model, tracing a light propagation path of the preset light, and calculating an effective emissivity based on a tracing result of the light propagation path; and correcting temperature measurements in the effective temperature measurement area based on the effective emissivity to obtain a corrected temperature measurement result. The infrared thermal image is acquired, and is analyzed by image processing, thereby dynamically capturing the effective temperature measurement area. The effective emissivity between wire rods is calculated, and then the measured temperature of the wire rod is corrected, thereby improving the accuracy and stability of temperature measurement on wire rods.

Abstract: The present application discloses a convex lens-shaped narrow face copper plate for continuous casting molds and its utilization method. The narrow face copper plate includes a first hot face and a second hot face. A first connecting line being provided at a joint of the first hot face and the second hot face, and two such first connecting lines being provided. A cross section of the first hot face is a convex arc, and the first hot face extends from an top of the narrow face copper plate to a bottom of the narrow face copper plate, and a height of the first hot face protruding relative to a plane where the two first connecting lines are located gradually decreases from the top of the narrow face copper plate to the bottom of the narrow face copper plate.

Abstract: A sensor having improved shelf life is provided for determining concentration of a biomarker in a liquid sample. The sensor functions by electrochemical detection and requires use of a biomolecule, e.g., an enzyme that catalyzes an electron transfer reaction specific for the biomarker. The sensor requires use of a quaternary ammonium compound as a bio-linker. It further requires crosslinking of the biomolecule for improved stability.

Abstract: A system and method for beam management in a wireless network are provided. A learning module having a trained classification module processes received I/Q input samples to determine transmitted beam information of incoming RF transmissions. The learning module includes a beam inference engine to determine waveforms waveform characteristics of incoming RF transmissions beams, and an angle of arrival engine operative to determine an angle of arrival of the incoming RF transmissions beams on an antenna array. An incoming RF transmission beam and angle of arrival are selected based on the determined waveforms for beam management operations.

Abstract: An implant system includes an electrode portion comprising plural electrodes to perform nerve stimulation and nerve sensing, an impedance controller configured to selectively connect the plural electrodes between a stimulator to perform nerve stimulation and a sensor to perform nerve sensing based on a control signal, and set an impedance of each of the plural electrodes, and a processor configured to control a contact impedance by the plural electrodes by generating the control signal to control at least one of plural switches connected respectively to the plural electrodes, or variable resistors connected respectively to the plural electrodes, based on at least one of a selectively set purpose of the plural electrodes or a position of an electrode to which nerve stimulation is to be provided.

Abstract: Embodiments identify joints of a multi-limb body in an image. One such embodiment unifies depth of a plurality of multi-scale feature maps generated from an image of a multi-limb body to create a plurality of feature maps each having a same depth. In turn, for each of the plurality of feature maps having the same depth, an initial indication of one or more joints in the image is generated. The one or more joints are located at an interconnection of a limb to the multi-limb body or at an interconnection of a limb to another limb. To continue, a final indication of the one or more joints in the image is generated using each generated initial indication of the one or more joints.

Abstract: The invention relates to a large-scale three-dimensional physical simulation test system for the whole development process of deep engineering rock burst. A CO2 blast cracking device, a dynamic fiber grating and ultrasonic probes are pre-embedded in a physical model sample of similar materials. Acoustic emission probes are pre-mounted on the boundary of a sample. A tunnel excavated in the sample is provided with a three-way acceleration sensor and an industrial endoscope. A sample 3D printer and a drop hammer impact device are arranged outside the three-dimensional static stress loading device. A hydraulic oil source and a controller are arranged outside the three-dimensional static stress loading device and mounted on the ground. The controller is connected with a computer.

Abstract: In an embodiment, a method monitors, within a global navigation satellite system (GNSS) limited zone, an intra-zone location of a vehicle having a GNSS receiver, the intra-zone location being within the limited zone. The method determines a simulated intra-zone location of the vehicle based on the intra-zone location monitored to calculate a likely location of the vehicle. The method calculates a global location of the vehicle based on the intra-zone location and the location of the GNSS limited zone within a global network of limited zones. The method broadcasts, from a transmitter within the GNSS limited zone, a GNSS signal representing the global location of the vehicle.

Abstract: A mixed rare earth concentrate mineral and suspended mineral phase transformation-clean leaching system and a method thereof achieve low-temperature phasing transformation of a rare earth mineral. The system includes a Venturi dryer, a multi-stage separator, a suspension preheating decomposition furnace, a multi-state fluidization sealing valve, a mineral phase transformation machine, a ball mill, a multi-stage acid leaching tank, an alkali leaching tank and a neutralization tank.

Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering an effective amount of a pharmaceutical composition including a PUFA-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system to a subject in need of treatment, and treating cancer. A method of overcoming multidrug resistance by exposing a multidrug resistant cell to an effective amount of a pharmaceutical composition including an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system, and inducing the death of the multidrug resistant cell. A method of eliminating a cancer stem cell. Methods of reducing stemness of a cancer stem cell, retaining drug in the body, and providing a slower release profile.

Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer.

Abstract: Disclosed herein are hydrogel compositions comprising a triblock copolymer having a formula A-B-A, wherein A is a polycaprolactone (PCL) block or a polyvalerolactone (PVL) block and B is a polyethylene glycol (PEG) block. Also disclosed are methods of making a hydrogel comprising providing a photoinitiator and a triblock copolymer having a formula A-B-A, wherein the triblock copolymer comprises one or more ethylenically unsaturated moieties; and photocrosslinking the triblock copolymer, thereby forming a hydrogel.

Abstract: A microwave drill bit capable of achieving fracturing of a borehole wall and end of a deep hard rock while drilling and a use method thereof are provided. The microwave drill bit comprises a microwave drill bit body, wherein a support frame front plate, a metal sleeve and a water inlet ring sequentially sleeve on the microwave drill bit body, the metal sleeve is connected with a rotary drive I mounted on the support frame front plate, the microwave drill body is connected with a microwave mode converter and a microwave splitter II respectively, the microwave mode converter and the microwave splitter II are connected with a microwave splitter I by a rectangular waveguide, the microwave splitter I is sequentially connected with a microwave rotating joint, a fixed waveguide and a microwave generator, and the microwave rotating joint is connected with a rotary drive II mounted on the support frame rear plate.

Abstract: A self-optimizing operating system for next-generation cellular networks is provided. The system provides telecommunications operators with an efficient and flexible network control platform that hides low-level network details through a virtual network abstraction and allows them to define centralized and high-level control objectives with no need for in-depth and detailed knowledge of cross-layer optimization theory or the underlying wireless protocol stack implementation.