Patents Assigned to Northeastern University
  • Patent number: 12288360
    Abstract: Methods and systems for providing a dataset of human in-bed poses include simultaneously gathered images of in-bed poses of humans from imaging modalities including red-green-blue (RGB) and one or more of long wavelength infrared (LWIR), depth imaging, and pressure mapping. The images are obtained under a lighting condition and a cover condition. The dataset can be used to train a model of estimating human in-bed poses and for methods of estimating human in-bed poses. Methods and systems of estimating three-dimensional human poses from two-dimensional input images are provided.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: April 29, 2025
    Assignee: Northeastern University
    Inventors: Sarah Ostadabbas, Shuangjun Liu, Xiaofei Huang, Nihang Fu
  • Patent number: 12289205
    Abstract: A framework for joint computation, caching, and request forwarding in data-centric computing-based networks comprises a virtual control plane, which operates on request counters for computations and data, and an actual plane, which handles computation requests, data requests, data objects and computation results in the physical network. A throughput optimal policy, implemented in the virtual plane, provides a basis for adaptive and distributed computation, caching, and request forwarding in the actual plane. The framework provides superior performance in terms of request satisfaction delay as compared with several baseline policies over multiple network topologies.
    Type: Grant
    Filed: February 29, 2024
    Date of Patent: April 29, 2025
    Assignee: Northeastern University
    Inventors: Edmund Meng Yeh, Khashayar Kamran
  • Patent number: 12280374
    Abstract: Disclosed are nanofluidic analytical devices. The devices employ a sample processing region that includes a plurality of fluidically connected sample handling elements that, in combination, affect a physical change on a sample introduced into the sample processing region. This physical change can include, for example, purification of an analyte of interest present in the sample, concentration of an analyte of interest present in the sample, chemical modification (e.g., cleavage and/or chemical derivatization) of an analyte of interest present in the sample, or a combination thereof. The analytical devices further include a nanochannel comprising a plurality of in-plane nanopores in series fluidically coupled to the sample processing region. The in-plane nanopores can be used to detect and/or analyze analyte(s) present in the sample following processing by the sample processing region. These analytical devices can advantageously provide for the label-free detection of single molecules.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: April 22, 2025
    Assignees: University of Kansas, Univ. of N Carolina at Chapel Hill, Board of Supervisors of LSU and A&M College, Northeastern University, Clarkson University
    Inventors: Steven A. Soper, Collin J. McKinney, Elizabeth Podlaha-Murphy, Sunggook Park
  • Patent number: 12269212
    Abstract: A composite material of particles disposed in a matrix material is provided in which the particles have an asymmetric geometric shape with a longest dimension and a shortest dimension different from the longest dimension. Adjacent volume portions of the composite material are arranged in a mosaic pattern to abut along an interface or surface forming a common boundary between the adjacent volume portions. The particles within the adjacent volume portions are arranged with differing orientations with respect to the interface. The orientations of the particles in the adjacent volume portions are selected so that a crack propagating on a crack propagation path through one or the other of the adjacent volume portions stops at or deflects to propagate along the interface. Methods of making composite materials are also provided.
    Type: Grant
    Filed: March 8, 2021
    Date of Patent: April 8, 2025
    Assignee: Northeastern University
    Inventors: Randall Erb, Robert Zando, Alain Karma, Ataollah Mesgarnejad
  • Patent number: 12255603
    Abstract: A microelectromechanical resonator device is provided having two-dimensional resonant rods. The resonator device has a piezoelectric layer formed with a plurality of alternating rods and trenches. A bottom electrode is in contact with a bottom surface of the piezoelectric layer. A top electrode metal grating of conductive strips is aligned in contact with corresponding rods of the piezoelectric layer.
    Type: Grant
    Filed: October 10, 2023
    Date of Patent: March 18, 2025
    Assignee: Northeastern University
    Inventors: Cristian Cassella, Xuanyi Zhao
  • Patent number: 12247245
    Abstract: Assays for compounds having a desired biological activity against one but not both of a pair of microorganism species utilize separately detectable labels. The first and second microorganisms are different from each other, the first microorganisms exhibit a first detectable label, the second microorganisms exhibit a second detectable label different from the first detectable label, and neither of the labels interferes with detection of the other label. In various embodiments, the first and second microorganisms are incubated with a candidate compound or a producer thereof. The different labels permit isolation of microorganisms exhibiting one of the labels but not the other, indicating the desired activity, and the compound responsible for this differential response is isolated.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: March 11, 2025
    Assignee: Northeastern University
    Inventors: Kim Lewis, Anthony D'Onofrio, Thomas Curtis, Charlotte Berkes
  • Patent number: 12235236
    Abstract: Devices and methods for detecting an analyte in a gas involve the use of plasmonic excitation of a nanostructured sensing element that is tuned to absorb at a narrow bandwidth specific for light absorbed by the analyte. The sensing element can be used as a capacitive or inductive element in a circuit.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: February 25, 2025
    Assignee: Northeastern University
    Inventors: Anthony Childress, Ahmed Busnaina
  • Patent number: 12230150
    Abstract: Methods and systems are provided for controlling an unmanned aerial vehicle (UAV) swarm network including receiving, at a control terminal, an operator input defining a plurality of network performance directives, constructing a network control model representing the plurality of network performance directives, decomposing the network control model into a plurality of sub-models, generating, via the control terminal, a distributed UAV control model corresponding to each of the distributed sub-models, transmitting the generated distributed UAV control models to each of a plurality of UAVs of the UAV swarm network, executing, at each of the plurality of UAVs, at least one of the distributed UAV control models, and changing, responsive to the execution of the distributed UAV control models, an operating condition of at least one of the plurality of UAVs to satisfy the network performance directives.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: February 18, 2025
    Assignee: Northeastern University
    Inventors: Tommaso Melodia, Lorenzo Bertizzolo, Zhangyu Guan, Salvatore D'Oro
  • Patent number: 12231297
    Abstract: Provided herein are systems for controlling a network of distributed non-terrestrial nodes including a control framework operative to train and control a plurality of the non-terrestrial nodes, the control framework including a control interface in communication with a network operator to receive one or more specified control objectives, and a learning engine operative to train a virtual non-terrestrial network, wherein the control framework is further operative to transfer knowledge gained through the training of the virtual non-terrestrial network to the network of distributed non-terrestrial nodes as data-driven logic unit configurations tailored for the specified control objectives.
    Type: Grant
    Filed: June 22, 2022
    Date of Patent: February 18, 2025
    Assignee: Northeastern University
    Inventors: Lorenzo Bertizzolo, Tommaso Melodia, Salvatore D'Oro, Hai Cheng
  • Patent number: 12226203
    Abstract: Provided herein are systems and methods for estimating contact pressure of a human lying on a surface including one or more imaging devices having imaging sensors oriented toward the surface, a processor and memory, including a trained model for estimating human contact pressure trained with a dataset including a plurality of human lying poses including images generated from at least one of a plurality of imaging modalities including at least one of a red-green-blue modality, a long wavelength infrared modality, a depth modality, or a pressure map modality, wherein the processor can receive one or more images from the imaging devices of the human lying on the surface and a source of one or more physical parameters of the human to determine a pressure map of the human based on the one or more images and the one or more physical parameters.
    Type: Grant
    Filed: June 3, 2022
    Date of Patent: February 18, 2025
    Assignee: Northeastern University
    Inventors: Sarah Ostadabbas, Shuangjun Liu
  • Patent number: 12218734
    Abstract: A system and method for beam management in a wireless network are provided. A learning module having a trained classification module processes received I/Q input samples to determine transmitted beam information of incoming RF transmissions. The learning module includes a beam inference engine to determine waveforms waveform characteristics of incoming RF transmissions beams, and an angle of arrival engine operative to determine an angle of arrival of the incoming RF transmissions beams on an antenna array. An incoming RF transmission beam and angle of arrival are selected based on the determined waveforms for beam management operations.
    Type: Grant
    Filed: January 5, 2023
    Date of Patent: February 4, 2025
    Assignee: Northeastern University
    Inventors: Michele Polese, Francesco Restuccia, Tommaso Melodia
  • Patent number: 12213784
    Abstract: A sensor having improved shelf life is provided for determining concentration of a biomarker in a liquid sample. The sensor functions by electrochemical detection and requires use of a biomolecule, e.g., an enzyme that catalyzes an electron transfer reaction specific for the biomarker. The sensor requires use of a quaternary ammonium compound as a bio-linker. It further requires crosslinking of the biomolecule for improved stability.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: February 4, 2025
    Assignee: Northeastern University
    Inventors: Yunqing Du, Ming L. Wang
  • Patent number: 12205317
    Abstract: Embodiments identify joints of a multi-limb body in an image. One such embodiment unifies depth of a plurality of multi-scale feature maps generated from an image of a multi-limb body to create a plurality of feature maps each having a same depth. In turn, for each of the plurality of feature maps having the same depth, an initial indication of one or more joints in the image is generated. The one or more joints are located at an interconnection of a limb to the multi-limb body or at an interconnection of a limb to another limb. To continue, a final indication of the one or more joints in the image is generated using each generated initial indication of the one or more joints.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: January 21, 2025
    Assignee: Northeastern University
    Inventors: Yun Fu, Songyao Jiang, Bin Sun
  • Patent number: 12196866
    Abstract: In an embodiment, a method monitors, within a global navigation satellite system (GNSS) limited zone, an intra-zone location of a vehicle having a GNSS receiver, the intra-zone location being within the limited zone. The method determines a simulated intra-zone location of the vehicle based on the intra-zone location monitored to calculate a likely location of the vehicle. The method calculates a global location of the vehicle based on the intra-zone location and the location of the GNSS limited zone within a global network of limited zones. The method broadcasts, from a transmitter within the GNSS limited zone, a GNSS signal representing the global location of the vehicle.
    Type: Grant
    Filed: May 10, 2022
    Date of Patent: January 14, 2025
    Assignee: Northeastern University
    Inventors: Matthew T. Kling, Daniel Lau, Kenneth Lile Witham, Pau Closas, Gerald Mycko LaMountain
  • Publication number: 20250009658
    Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering an effective amount of a pharmaceutical composition including a PUFA-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system to a subject in need of treatment, and treating cancer. A method of overcoming multidrug resistance by exposing a multidrug resistant cell to an effective amount of a pharmaceutical composition including an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system, and inducing the death of the multidrug resistant cell. A method of eliminating a cancer stem cell. Methods of reducing stemness of a cancer stem cell, retaining drug in the body, and providing a slower release profile.
    Type: Application
    Filed: July 16, 2024
    Publication date: January 9, 2025
    Applicants: TargaGenix, Inc., Research Foundation for State University New York, Northeastern University
    Inventors: James E. EGAN, Iwao OJIMA, Mansoor M. AMIJI, Galina Ivanovna BOTCHKINA
  • Patent number: 12191656
    Abstract: The presently disclosed embodiments generally relate to systems, devices, and methods for sensing and charging of electronic devices using coils. In some embodiments, the presently disclosed system can include a pad, a charging foot, and a backpack. The pad can include one or more nested coils therein that can sense one or more corresponding receiver coils of an unmanned aerial vehicles (UAV) that landed thereon. The nested coils of the pad can provide charging energy to the UAV independent of the location along the pad in which the UAV landed, and no precise alignment between the receiver coils and the charging coils is required. The charging foot can be attached to one or more legs of the UAV, and can include a receiver coil and circuitry to regulate energy received by the coil to a charging voltage level that can be provided to the battery.
    Type: Grant
    Filed: September 28, 2022
    Date of Patent: January 7, 2025
    Assignee: Northeastern University
    Inventors: Yousof Naderi, Kaushik Chowdhury
  • Patent number: 12186428
    Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer.
    Type: Grant
    Filed: November 14, 2022
    Date of Patent: January 7, 2025
    Assignees: TargaGenix, Inc., The Research Foundation for the State University of New York, Northeastern University
    Inventors: James E. Egan, Mansoor M. Amiji, Iwao Ojima
  • Patent number: 12192792
    Abstract: A self-optimizing operating system for next-generation cellular networks is provided. The system provides telecommunications operators with an efficient and flexible network control platform that hides low-level network details through a virtual network abstraction and allows them to define centralized and high-level control objectives with no need for in-depth and detailed knowledge of cross-layer optimization theory or the underlying wireless protocol stack implementation.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: January 7, 2025
    Assignee: Northeastern University
    Inventors: Tommaso Melodia, Leonardo Bonati, Salvatore D'Oro
  • Patent number: 12181440
    Abstract: Disclosed is a method of desorbing an adsorbed material by subjecting to energy a diazirine adsorbed on a solid surface or a layer on the solid surface, which causes the diazirine to form a carbene and nitrogen gas; and using the energy of the resultant nitrogen gas to desorb the adsorbed material from the solid surface or a layer on the same. Also disclosed is a method of reacting the resultant carbene with (a) a material in the gas phase proximal to the first solid surface; (b) a material adsorbed on a second solid surface proximal to the first solid surface; or (c) a second solid surface proximal to the first solid surface.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: December 31, 2024
    Assignee: Northeastern University
    Inventors: Roger W. Giese, Pushkar Kulkarni
  • Patent number: 12171854
    Abstract: Disclosed are polymers, methods of making polymers, and compositions, focused on cross-linking heterocycles comprising a moiety of Formula I with thiols and thiolates.
    Type: Grant
    Filed: March 15, 2022
    Date of Patent: December 24, 2024
    Assignee: Northeastern University
    Inventor: Jeffrey N. Agar