Patents Assigned to Northeastern University
  • Patent number: 12095513
    Abstract: Embodiments disclosed herein may be implemented in the form of a method or corresponding apparatus for receiving or transmitting network communications carried at acoustic wavelengths via an acoustic medium. The corresponding method or apparatus may include a gate-level digital hardware module communicatively coupled to a communications module and define therein logic blocks configured to perform respective primitive processing functions, sequences of the logic blocks being capable of processing data units in accordance with any of the multiple communications protocols on a data unit-by-data unit basis without reconfiguring.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: September 17, 2024
    Assignee: Northeastern University
    Inventors: Tommaso Melodia, Emrecan Demirors
  • Patent number: 12072396
    Abstract: A solidly mounted resonator (SMR)-based magnetoelectric (ME) antenna comprises a substrate, a Bragg reflector disposed on the substrate, a magnetostrictive/piezoelectric ME composite element disposed on the Bragg reflector, a first electrically conductive contact and a second electrically conductive contact. The first contact is disposed between the Bragg reflector and the magnetostrictive/piezoelectric ME composite element and electrically coupled to a bottom surface of the magnetostrictive/piezoelectric ME composite element. The second contact is disposed on top of the magnetostrictive/piezoelectric ME composite element and electrically coupled to the top of the magnetostrictive/piezoelectric ME composite element. The magnetostrictive/piezoelectric ME composite element comprises a magnetorestrictive multilayer deposited on a piezoelectric layer. The magnetorestrictive multilayer produces an in-plane uniaxial magnetic anisotropy (UMA). The UMA is a twofold UMA that exhibits a symmetric radiation pattern.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: August 27, 2024
    Assignee: Northeastern University
    Inventors: Nian-Xiang Sun, Neville Sun, Xianfeng Lian, Huaihao Chen
  • Patent number: 12065632
    Abstract: The invention provides cell culture chambers and methods of use thereof. In certain embodiments, the cell culture chambers and methods provide for an expansion and stimulation of T-cells using autologous antigen-presented cells to provide a therapeutic T-cell product that can mobilize a patient's own immune system in a manner that selectively targets a patient's tumor.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: August 20, 2024
    Assignee: Northeastern University
    Inventor: Shashi K. Murthy
  • Patent number: 12064768
    Abstract: The technology provides arrays of microwells with reversible shape for culture, analysis, and recovery of individual cells or groups of cells. The microwells are reversibly formed by vacuum-induced deflection of an elastomeric membrane into an array of microwell molds formed in a microwell substrate. The shape of each microwell or groups of microwells can be selectively altered by applying or releasing vacuum to individual microwells. The devices, systems, and methods utilizing the technology enable collection of individual cells for further study or therapeutic use without the need for micromanipulation.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: August 20, 2024
    Assignee: Northeastern University
    Inventors: Tania Konry, Giovanni Ugolini
  • Patent number: 12060398
    Abstract: Disclosed herein are engineered bacteria that manufacture biofilms from bacterial amyloid structures. These biofilms and biofilm matrices are capable of generating fibrous proteinaceous networks and being used as 3D-printing inks.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: August 13, 2024
    Assignee: Northeastern University
    Inventors: Arjirios Sourlis, Anna Duraj-Thatte, Avinash Manjula Basavanna, Neel Satish Joshi
  • Patent number: 12062249
    Abstract: A system, neural network, and corresponding method generate 3D landmarks associated with an object in a 2D image. An embodiment is a system comprising a neural network detector configured to produce planar coordinates of landmarks at points of the object in the 2D image and a depth coordinate estimator. The planar coordinates include planar coordinate pairs. The depth coordinate estimator is configured to receive the 2D image and the planar coordinates and to estimate a depth coordinate for each planar coordinate pair of each landmark to generate the 3D landmarks. The system reduces network parameters from MB to KB and has better performance relative to state-of-the-art methods. The system may be configured to apply the 3D landmarks for face alignment, virtual face makeup, face recognition, eye gaze tracking, face synthesis, or other face related application.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: August 13, 2024
    Assignee: Northeastern University
    Inventors: Yun Fu, Bin Sun
  • Patent number: 12055438
    Abstract: Ultra-low power methods and sensor devices are provided for determining the presence and magnitude of electromagnetic radiation or other signals. The sensor devices and methods provide both qualitative and quantitative analyses and can be deployed in remote locations for continuous monitoring over years without requiring a replacement power supply.
    Type: Grant
    Filed: April 26, 2022
    Date of Patent: August 6, 2024
    Assignee: Northeastern University
    Inventors: Matteo Rinaldi, Vageeswar Rajaram, Zhenyun Qian, Sungho (Ryan) Kang, Sila Deniz Calisgan, Antea Risso
  • Patent number: 12046028
    Abstract: A compiler system for deploying CNN models to FPGA-based high-performance accelerators is provided. The compiler system comprises a compiler front end and a compiler back end, as well as a runtime library and an accelerator; the compiler front end is used for the quantization of CNN models to be deployed based on the ONNX model and a training data set, and the IR Graph corresponding to the CNN model to be deployed is obtained; the compiler back end is used to determine instructions and configuration information; the instruction set architecture comprises CONY, MAXP, AVGP, ADD and FC, and the configuration information comprises pre-trained weights and bias, packet descriptors and key-value pairs representing control registers; the runtime library is used to store instructions and configuration files to DRAM, and FPGA is configured according to the configuration information of the model.
    Type: Grant
    Filed: January 11, 2024
    Date of Patent: July 23, 2024
    Assignee: NORTHEASTERN UNIVERSITY
    Inventors: Gang Wu, Yongzheng Chen, Shuaibo Yin
  • Patent number: 12040703
    Abstract: Side channel attacks (SCA) such as correlation power analysis (CPA) have been demonstrated to be very effective in breaking cryptographic engines. The inherent dependence of the power consumption on the secret key can be exploited by statistical analysis to retrieve the key. Various embodiments disclosed herein relate to a new power obfuscation switched capacitor (POSC) DC-DC converter design, which can conceal the leakage of information through power consumption. It works by adding an extra phase to the conventional two-phase switched capacitor (SC) converter, during which a part of the charge from the flying capacitor is extracted and stored on a storage capacitor. This guarantees that the same amount of charge is drawn from the input power supply in each cycle. The design was successfully evaluated by analyzing the power supply to an Advanced Encryption Standard (AES) unit powered by the converter.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: July 16, 2024
    Assignee: Northeastern University
    Inventors: Aatmesh Shrivastava, Nikita Mirchandani
  • Patent number: 12034310
    Abstract: Wireless power transfer (WPT) efficiency is enhanced using an ultra-low power (ULP) distributed beamforming technique. A phase and frequency offset correction technique is used for beam-forming optimization, a backscattering communication technique is used to reduce power over-head, and a new rectifier and MPT method is used for high efficiency RF-to-DC conversion.
    Type: Grant
    Filed: July 11, 2022
    Date of Patent: July 9, 2024
    Assignee: Northeastern University
    Inventor: Aatmesh Shrivastava
  • Patent number: 12034434
    Abstract: Piezoelectric acoustic metamaterial resonators include a piezoelectric substrate having a top surface and a bottom surface and a plurality of magnetostrictive members disposed on the top surface of the piezoelectric substrate and extending along a length of the piezoelectric substrate and spaced across a width of the piezoelectric substrate.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: July 9, 2024
    Assignee: Northeastern University
    Inventor: Cristian Cassella
  • Patent number: 12028824
    Abstract: Provided herein are methods and apparatus for a self-synchronizing software defined radio apparatus wherein the method includes instructing, by a leader module of an RF clock module of the software defined radio apparatus and via a controller module comprising a central coordinator operative to provide a data bridge, a radio frequency (RF) transceiver to transmit a two-tone frequency signal at f1 and f2 over air, separated by a desired input clock frequency, the RF transceiver operative to receive and transmit RF signals, receiving, at a follower module, a transmitted signal, extracting, by the follower module, an envelope of the received signal, and passing the received signal through a filter to obtain a reference clock without modifying existing physical/link layer protocols.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: July 2, 2024
    Assignee: Northeastern University
    Inventors: Kaushik Chowdhury, Ufuk Muncuk, Yousof Naderi
  • Patent number: 12018342
    Abstract: Heat treatment equipment for metal plate strips, and a roller quenching flow zone control device for metal plate strips. The device includes a middle water diversion ring sleeve and edge water diversion ring sleeves; the middle water diversion ring sleeve is installed at the middle processing groove in a slit nozzle rear spiral roller and a high-density nozzle rear spiral roller in a high-pressure cooling section of a roller quenching machine; and the edge water diversion ring sleeves are installed at the processing grooves in ¼ and ¾ positions in the width direction of the slit nozzle rear spiral roller in the high-pressure cooling section of the roller quenching machine. This can effectively realize uniform distribution of cooling water on the surface of the plate strip, reduce the phenomenon of local non-uniform cooling caused by siltation of cooling water.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: June 25, 2024
    Assignee: NORTHEASTERN UNIVERSITY
    Inventors: Tianliang Fu, Xiangtao Deng, Guodong Wang, Zhifu Zhang, Guanghao Liu, Mingjun Zheng, Guozhi Song, Wei Cui, Min Song, Zhiwei Jia
  • Patent number: 12001178
    Abstract: Provided is an aluminum oxide production operation optimization system and method based on a cloud-edge collaboration, which relates to the technical field of an aluminum oxide production operation optimization. According to the system and method, firstly the whole-flow data in the aluminum oxide production process is acquired, the data is pre-processed, then the pre-processed data is transmitted to a local collaboration production operation optimization unit, the local collaboration production operation optimization unit firstly judges working conditions for the current aluminum oxide production process, an optimization strategy needing to be operated at present is automatically switched according to the working condition, and the local operation optimization strategy obtains the actual setting value of the aluminum oxide production operation indexes.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: June 4, 2024
    Assignee: NORTHEASTERN UNIVERSITY
    Inventors: Jinliang Ding, Changxin Liu, Depeng Xu, Tianyou Chai
  • Patent number: 11994508
    Abstract: A method and system for performing single molecule proteomics utilizing a nanopore sensor to measure an electronic signature of protein or peptide being transported through the nanopore from a first chamber to a second chamber. The protein's electronic signature is a function of ionic current over time. The method and system utilizing an agent, such as guanidinium chloride, to bind to the nanopore's interior and provide an electroosmotic force within the nanopore. The electroosmotic force, in some embodiments, enables stretching and unfolding of the protein during transport through the nanopore. The agent may also or alternatively induce the unfolding of the protein before transport through the nanopore and/or provide force moving the protein through the nanopore.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: May 28, 2024
    Assignees: NORTHEASTERN UNIVERSITY, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Meni Wanunu, Luning Yu, Aleksei Aksimentiev, Behzad Mehrafrooz
  • Patent number: 11982596
    Abstract: The invention provides a method and system for a blast-induced vibration monitoring of a tunnel in high asymmetric in-situ stresses. According to the method, triaxial vibration sensors are respectively fixed in areas having different radial depths inside surrounding rocks of a stress concentration area behind a tunnel face of the tunnel in high asymmetric in-situ stresses, and each triaxial vibration sensor monitors blast vibration velocity and acceleration at a position thereof. The system comprises a plurality of triaxial vibration sensors which are fixed in areas having different radial depths inside surrounding rocks of a stress concentration area behind a tunnel face of the tunnel in high asymmetric in-situ stresses, and each triaxial vibration sensor is used for monitoring blast vibration velocity and acceleration at a position thereof. The method and system can improve the safety and the efficiency of tunnel excavation construction.
    Type: Grant
    Filed: November 25, 2022
    Date of Patent: May 14, 2024
    Assignee: NORTHEASTERN UNIVERSITY
    Inventors: Benguo He, Xiating Feng, Jie Wang, Shichen Qiu, Xiangrui Meng, Lei Wang
  • Patent number: 11969713
    Abstract: Functionalized catalysts for use in a hydrogen evolution reaction (HER) contain nanoparticles containing a transition metal enveloped in layers of graphene, which renders the nanoparticles resistant to passivation while maintaining an optimal ratio of transition metal and transition metal oxide in the nanoparticles. The catalysts can be utilized with anionic exchange polymer membranes for hydrogen production by alkaline water electrolysis.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: April 30, 2024
    Assignee: Northeastern University
    Inventors: Sanjeev Mukerjee, Robert Allen, Huong Thi Thanh Doan, Ian Kendrick
  • Patent number: 11972856
    Abstract: Aspects of the present disclosure describe systems and methods for predicting an intra-aortic pressure of a patient receiving hemodynamic support from a transvalvular micro-axial heart pump. In some implementations, an intra-aortic pressure time series is derived from measurements of a pressure sensor of the transvalvular micro-axial heart pump and a motor speed time series is derived from a measured back electromotive force of a motor of the transvalvular micro-axial heart pump. Furthermore, in some implementations, machine learning algorithms, such as deep learning, are applied to the intra-aortic pressure and motor speed time series to accurately predict an intra-aortic pressure of the patient. In some implementations, the prediction is short-term (e.g., approximately 5 minutes in advance).
    Type: Grant
    Filed: January 13, 2023
    Date of Patent: April 30, 2024
    Assignees: Abiomed, Inc., Northeastern University
    Inventors: Ahmad El Katerji, Erik Kroeker, Elise Jortberg, Rose Yu, Rui Wang
  • Patent number: 11969266
    Abstract: A deep learning medical device implantable in a body is provided. The device includes a processing and communication unit and a sensing and actuation unit. The processing and communication unit includes a deep learning module including a neural network trained to process the input samples, received from the sensing and actuation unit, through a plurality of layers to classify physiological parameters and provide classification results. A communication interface in communication with the deep learning module receives the classification results for ultrasonic transmission through biological tissue. Methods of sensing and classifying physiological parameters of a body and methods of embedding deep learning into an implantable medical device are also provided.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: April 30, 2024
    Assignee: Northeastern University
    Inventors: Daniel Uvaydov, Raffaele Guida, Francesco Restuccia, Tommaso Melodia
  • Patent number: RE50096
    Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering an effective amount of a pharmaceutical composition including a PUFA-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system to a subject in need of treatment, and treating cancer. A method of overcoming multidrug resistance by exposing a multidrug resistant cell to an effective amount of a pharmaceutical composition including an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system, and inducing the death of the multidrug resistant cell. A method of eliminating a cancer stem cell. Methods of reducing stemness of a cancer stem cell, retaining drug in the body, and providing a slower release profile.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: August 27, 2024
    Assignees: Targagenix, Inc., Northeastern University
    Inventors: James E. Egan, Iwao Ojima, Mansoor M. Amiji, Galina Ivanovna Botchkina