Patents Assigned to Northeastern University
  • Patent number: 12235236
    Abstract: Devices and methods for detecting an analyte in a gas involve the use of plasmonic excitation of a nanostructured sensing element that is tuned to absorb at a narrow bandwidth specific for light absorbed by the analyte. The sensing element can be used as a capacitive or inductive element in a circuit.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: February 25, 2025
    Assignee: Northeastern University
    Inventors: Anthony Childress, Ahmed Busnaina
  • Patent number: 12230150
    Abstract: Methods and systems are provided for controlling an unmanned aerial vehicle (UAV) swarm network including receiving, at a control terminal, an operator input defining a plurality of network performance directives, constructing a network control model representing the plurality of network performance directives, decomposing the network control model into a plurality of sub-models, generating, via the control terminal, a distributed UAV control model corresponding to each of the distributed sub-models, transmitting the generated distributed UAV control models to each of a plurality of UAVs of the UAV swarm network, executing, at each of the plurality of UAVs, at least one of the distributed UAV control models, and changing, responsive to the execution of the distributed UAV control models, an operating condition of at least one of the plurality of UAVs to satisfy the network performance directives.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: February 18, 2025
    Assignee: Northeastern University
    Inventors: Tommaso Melodia, Lorenzo Bertizzolo, Zhangyu Guan, Salvatore D'Oro
  • Patent number: 12226203
    Abstract: Provided herein are systems and methods for estimating contact pressure of a human lying on a surface including one or more imaging devices having imaging sensors oriented toward the surface, a processor and memory, including a trained model for estimating human contact pressure trained with a dataset including a plurality of human lying poses including images generated from at least one of a plurality of imaging modalities including at least one of a red-green-blue modality, a long wavelength infrared modality, a depth modality, or a pressure map modality, wherein the processor can receive one or more images from the imaging devices of the human lying on the surface and a source of one or more physical parameters of the human to determine a pressure map of the human based on the one or more images and the one or more physical parameters.
    Type: Grant
    Filed: June 3, 2022
    Date of Patent: February 18, 2025
    Assignee: Northeastern University
    Inventors: Sarah Ostadabbas, Shuangjun Liu
  • Patent number: 12231297
    Abstract: Provided herein are systems for controlling a network of distributed non-terrestrial nodes including a control framework operative to train and control a plurality of the non-terrestrial nodes, the control framework including a control interface in communication with a network operator to receive one or more specified control objectives, and a learning engine operative to train a virtual non-terrestrial network, wherein the control framework is further operative to transfer knowledge gained through the training of the virtual non-terrestrial network to the network of distributed non-terrestrial nodes as data-driven logic unit configurations tailored for the specified control objectives.
    Type: Grant
    Filed: June 22, 2022
    Date of Patent: February 18, 2025
    Assignee: Northeastern University
    Inventors: Lorenzo Bertizzolo, Tommaso Melodia, Salvatore D'Oro, Hai Cheng
  • Patent number: 12213784
    Abstract: A sensor having improved shelf life is provided for determining concentration of a biomarker in a liquid sample. The sensor functions by electrochemical detection and requires use of a biomolecule, e.g., an enzyme that catalyzes an electron transfer reaction specific for the biomarker. The sensor requires use of a quaternary ammonium compound as a bio-linker. It further requires crosslinking of the biomolecule for improved stability.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: February 4, 2025
    Assignee: Northeastern University
    Inventors: Yunqing Du, Ming L. Wang
  • Patent number: 12218734
    Abstract: A system and method for beam management in a wireless network are provided. A learning module having a trained classification module processes received I/Q input samples to determine transmitted beam information of incoming RF transmissions. The learning module includes a beam inference engine to determine waveforms waveform characteristics of incoming RF transmissions beams, and an angle of arrival engine operative to determine an angle of arrival of the incoming RF transmissions beams on an antenna array. An incoming RF transmission beam and angle of arrival are selected based on the determined waveforms for beam management operations.
    Type: Grant
    Filed: January 5, 2023
    Date of Patent: February 4, 2025
    Assignee: Northeastern University
    Inventors: Michele Polese, Francesco Restuccia, Tommaso Melodia
  • Patent number: 12205317
    Abstract: Embodiments identify joints of a multi-limb body in an image. One such embodiment unifies depth of a plurality of multi-scale feature maps generated from an image of a multi-limb body to create a plurality of feature maps each having a same depth. In turn, for each of the plurality of feature maps having the same depth, an initial indication of one or more joints in the image is generated. The one or more joints are located at an interconnection of a limb to the multi-limb body or at an interconnection of a limb to another limb. To continue, a final indication of the one or more joints in the image is generated using each generated initial indication of the one or more joints.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: January 21, 2025
    Assignee: Northeastern University
    Inventors: Yun Fu, Songyao Jiang, Bin Sun
  • Patent number: 12196866
    Abstract: In an embodiment, a method monitors, within a global navigation satellite system (GNSS) limited zone, an intra-zone location of a vehicle having a GNSS receiver, the intra-zone location being within the limited zone. The method determines a simulated intra-zone location of the vehicle based on the intra-zone location monitored to calculate a likely location of the vehicle. The method calculates a global location of the vehicle based on the intra-zone location and the location of the GNSS limited zone within a global network of limited zones. The method broadcasts, from a transmitter within the GNSS limited zone, a GNSS signal representing the global location of the vehicle.
    Type: Grant
    Filed: May 10, 2022
    Date of Patent: January 14, 2025
    Assignee: Northeastern University
    Inventors: Matthew T. Kling, Daniel Lau, Kenneth Lile Witham, Pau Closas, Gerald Mycko LaMountain
  • Publication number: 20250009658
    Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering an effective amount of a pharmaceutical composition including a PUFA-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system to a subject in need of treatment, and treating cancer. A method of overcoming multidrug resistance by exposing a multidrug resistant cell to an effective amount of a pharmaceutical composition including an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system, and inducing the death of the multidrug resistant cell. A method of eliminating a cancer stem cell. Methods of reducing stemness of a cancer stem cell, retaining drug in the body, and providing a slower release profile.
    Type: Application
    Filed: July 16, 2024
    Publication date: January 9, 2025
    Applicants: TargaGenix, Inc., Research Foundation for State University New York, Northeastern University
    Inventors: James E. EGAN, Iwao OJIMA, Mansoor M. AMIJI, Galina Ivanovna BOTCHKINA
  • Patent number: 12186428
    Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer.
    Type: Grant
    Filed: November 14, 2022
    Date of Patent: January 7, 2025
    Assignees: TargaGenix, Inc., The Research Foundation for the State University of New York, Northeastern University
    Inventors: James E. Egan, Mansoor M. Amiji, Iwao Ojima
  • Patent number: 12192792
    Abstract: A self-optimizing operating system for next-generation cellular networks is provided. The system provides telecommunications operators with an efficient and flexible network control platform that hides low-level network details through a virtual network abstraction and allows them to define centralized and high-level control objectives with no need for in-depth and detailed knowledge of cross-layer optimization theory or the underlying wireless protocol stack implementation.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: January 7, 2025
    Assignee: Northeastern University
    Inventors: Tommaso Melodia, Leonardo Bonati, Salvatore D'Oro
  • Patent number: 12191656
    Abstract: The presently disclosed embodiments generally relate to systems, devices, and methods for sensing and charging of electronic devices using coils. In some embodiments, the presently disclosed system can include a pad, a charging foot, and a backpack. The pad can include one or more nested coils therein that can sense one or more corresponding receiver coils of an unmanned aerial vehicles (UAV) that landed thereon. The nested coils of the pad can provide charging energy to the UAV independent of the location along the pad in which the UAV landed, and no precise alignment between the receiver coils and the charging coils is required. The charging foot can be attached to one or more legs of the UAV, and can include a receiver coil and circuitry to regulate energy received by the coil to a charging voltage level that can be provided to the battery.
    Type: Grant
    Filed: September 28, 2022
    Date of Patent: January 7, 2025
    Assignee: Northeastern University
    Inventors: Yousof Naderi, Kaushik Chowdhury
  • Patent number: 12181440
    Abstract: Disclosed is a method of desorbing an adsorbed material by subjecting to energy a diazirine adsorbed on a solid surface or a layer on the solid surface, which causes the diazirine to form a carbene and nitrogen gas; and using the energy of the resultant nitrogen gas to desorb the adsorbed material from the solid surface or a layer on the same. Also disclosed is a method of reacting the resultant carbene with (a) a material in the gas phase proximal to the first solid surface; (b) a material adsorbed on a second solid surface proximal to the first solid surface; or (c) a second solid surface proximal to the first solid surface.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: December 31, 2024
    Assignee: Northeastern University
    Inventors: Roger W. Giese, Pushkar Kulkarni
  • Patent number: 12171854
    Abstract: Disclosed are polymers, methods of making polymers, and compositions, focused on cross-linking heterocycles comprising a moiety of Formula I with thiols and thiolates.
    Type: Grant
    Filed: March 15, 2022
    Date of Patent: December 24, 2024
    Assignee: Northeastern University
    Inventor: Jeffrey N. Agar
  • Patent number: 12174534
    Abstract: A scalable printing process capable of printing microscale and nanoscale features for additively manufacturing electronics is provided. This fast, directed assembly-based approach selectively prints microscale and nanoscale features on both rigid and flexible substrates. The printing speed is much faster than state-of-the-art inkjet and flexographic printing, and the resolution is two orders of magnitude higher, with minimum feature size of 100 nm. Feature patterns can be printed over large areas and require no special limitations on the assembled materials. Hydrophilic/hydrophobic patterns are used to direct deposition of nanomaterials to specific regions or to selectively assemble polymer blends to desired sites in a one-step process with high specificity and selectively. The selective deposition can be based on electrostatic forces, hydrogen bonding, or hydrophobic interactions.
    Type: Grant
    Filed: October 16, 2020
    Date of Patent: December 24, 2024
    Assignee: Northeastern University
    Inventors: Salman A. Abbasi, Zhimin Chai, Ahmed Busnaina
  • Patent number: 12178140
    Abstract: A thin film heterostructure of a topological insulator (TI) with a normal metal (NM) is used as a highly energy efficient and low power dissipation spin Hall Material (SHM). The TI material is sputter deposited onto a substrate and cooled in high vacuum, and an NM material is sputter deposited onto the TI film. The structure and method is compatible with complementary metal oxide (CMOS) processes, and with growth of large-area TI films for wafer-level device fabrication.
    Type: Grant
    Filed: December 2, 2021
    Date of Patent: December 24, 2024
    Assignee: Northeastern University
    Inventors: Nian-Xiang Sun, Nirjhar Bhattacharjee
  • Patent number: 12169145
    Abstract: Zero-power system for remote monitoring of heat sources is provided. The systems detect failure indicators of remote equipment including power substations, oil rigs, large inaccessible machinery in a factory, and communications equipment. The systems also can be used to detect the presence of people in buildings or in other locations, so as to improve HVAC utilization in large buildings. When the zero-power monitoring systems detect heat sources, such as the presence of people, failure indicators, or a targeted environmental signal, a circuit is closed using the energy of the detected radiation, and activating an RFID tag, a radio transmitter, or an alarm. The monitoring systems can remain deployed and active for many years without the need for battery replacement.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: December 17, 2024
    Assignee: Northeastern University
    Inventors: Matteo Rinaldi, Zhenyun Qian, Vageeswar Rajaram, Sungho Kang
  • Patent number: 12157901
    Abstract: Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: December 3, 2024
    Assignee: Northeastern University
    Inventors: Shashi K. Murthy, Bradley B. Collier
  • Patent number: 12155738
    Abstract: A system and method for joint dynamic interest request forwarding and dynamic cache placement and eviction and provided within the context of the Named Data Networking (NDN) architecture. The system and method employ a virtual control plane that operates on the user demand rate for data objects in the network, and an actual plane that handles Interest Packets and Data Packets. Distributed algorithms within the virtual plane achieve network load balancing through dynamic forwarding and caching, thereby maximizing the user demand rate that the NDN network can satisfy. A method of congestion control is also provided to achieve optimal network fairness using the VIP framework.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: November 26, 2024
    Assignees: Northeastern University, California Institute of Technology
    Inventors: Edmund Meng Yeh, Ying Cui, Ran Liu, Tracey Ho, Michael Burd, Derek Leong
  • Publication number: 20240384643
    Abstract: Disclosed are a borehole fracture-deformation-wave velocity integrated intelligent sensing apparatus and method for an engineering rock mass. The apparatus includes an in-hole monitoring execution unit and an out-hole monitoring unit which are connected by a cable; the in-hole monitoring execution unit includes a hole-diameter-adaptive crawling robot and a combined multifunctional probe assembly; the probe assembly includes a high-definition wide-angle camera, a laser radar probe, and an acoustic transceiver probe, and all the probes may be freely combined; the hole-diameter-adaptive crawling robot is of a waterproof sealed shell structure and is capable of charging a pressure inside to realize leakage detection, and the hole-diameter-adaptive crawling robot adopts lift-type electric crawler walking mechanisms capable of automatically adjusting a supporting force to avoid sliding. The apparatus can be used for intelligent long-term monitoring of borehole fracture, deformation and wave velocity.
    Type: Application
    Filed: March 7, 2024
    Publication date: November 21, 2024
    Applicant: Northeastern University
    Inventors: Jun ZHAO, Xiating FENG, Mengfei JIANG, Jiachao XUE, Chengxiang YANG