Patents Assigned to Northeastern University
-
Publication number: 20250032044Abstract: A method of determining an extent of visual spatial neglect of a patient includes providing a software-based test to the patient via a presentation apparatus positioned on the head of the patient and having a display device positioned close and in front of the eyes of the patient. EEG information is collected from the patient during the test via an EEG apparatus positioned on the head of the patient. Portions of the EEG information collected during the test are used to determine the extent of the visual spatial neglect of the patient. An indication of the extent of the visual spatial neglect of the patient is provided.Type: ApplicationFiled: March 30, 2023Publication date: January 30, 2025Applicants: UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, NORTHEASTERN UNIVERSITY, THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPT. OF VETERANS AFFAIRSInventors: Murat Akcakaya, Deniz Kocanaogullari, Emily Grattan, George F. Wittenberg, Jennifer Mak, Sarah Ostadabbas, Xiaofei Huang
-
Patent number: 12201841Abstract: An implant system includes an electrode portion comprising plural electrodes to perform nerve stimulation and nerve sensing, an impedance controller configured to selectively connect the plural electrodes between a stimulator to perform nerve stimulation and a sensor to perform nerve sensing based on a control signal, and set an impedance of each of the plural electrodes, and a processor configured to control a contact impedance by the plural electrodes by generating the control signal to control at least one of plural switches connected respectively to the plural electrodes, or variable resistors connected respectively to the plural electrodes, based on at least one of a selectively set purpose of the plural electrodes or a position of an electrode to which nerve stimulation is to be provided.Type: GrantFiled: December 15, 2021Date of Patent: January 21, 2025Assignees: Samsung Electronics Co., Ltd., NORTHEASTERN UNIVERSITYInventors: Junyeub Suh, Sangjoon Kim, Hui Fang, Jaehyeon Ryu
-
Patent number: 12205317Abstract: Embodiments identify joints of a multi-limb body in an image. One such embodiment unifies depth of a plurality of multi-scale feature maps generated from an image of a multi-limb body to create a plurality of feature maps each having a same depth. In turn, for each of the plurality of feature maps having the same depth, an initial indication of one or more joints in the image is generated. The one or more joints are located at an interconnection of a limb to the multi-limb body or at an interconnection of a limb to another limb. To continue, a final indication of the one or more joints in the image is generated using each generated initial indication of the one or more joints.Type: GrantFiled: February 10, 2021Date of Patent: January 21, 2025Assignee: Northeastern UniversityInventors: Yun Fu, Songyao Jiang, Bin Sun
-
Patent number: 12195826Abstract: A mixed rare earth concentrate mineral and suspended mineral phase transformation-clean leaching system and a method thereof achieve low-temperature phasing transformation of a rare earth mineral. The system includes a Venturi dryer, a multi-stage separator, a suspension preheating decomposition furnace, a multi-state fluidization sealing valve, a mineral phase transformation machine, a ball mill, a multi-stage acid leaching tank, an alkali leaching tank and a neutralization tank.Type: GrantFiled: September 8, 2023Date of Patent: January 14, 2025Assignee: NORTHEASTERN UNIVERSITYInventors: Peng Gao, Shuai Yuan, Jilai Ning, Yuexin Han, Yanjun Li, Yongsheng Sun, Wenbo Li
-
Patent number: 12196866Abstract: In an embodiment, a method monitors, within a global navigation satellite system (GNSS) limited zone, an intra-zone location of a vehicle having a GNSS receiver, the intra-zone location being within the limited zone. The method determines a simulated intra-zone location of the vehicle based on the intra-zone location monitored to calculate a likely location of the vehicle. The method calculates a global location of the vehicle based on the intra-zone location and the location of the GNSS limited zone within a global network of limited zones. The method broadcasts, from a transmitter within the GNSS limited zone, a GNSS signal representing the global location of the vehicle.Type: GrantFiled: May 10, 2022Date of Patent: January 14, 2025Assignee: Northeastern UniversityInventors: Matthew T. Kling, Daniel Lau, Kenneth Lile Witham, Pau Closas, Gerald Mycko LaMountain
-
Patent number: 12196723Abstract: The invention relates to a large-scale three-dimensional physical simulation test system for the whole development process of deep engineering rock burst. A CO2 blast cracking device, a dynamic fiber grating and ultrasonic probes are pre-embedded in a physical model sample of similar materials. Acoustic emission probes are pre-mounted on the boundary of a sample. A tunnel excavated in the sample is provided with a three-way acceleration sensor and an industrial endoscope. A sample 3D printer and a drop hammer impact device are arranged outside the three-dimensional static stress loading device. A hydraulic oil source and a controller are arranged outside the three-dimensional static stress loading device and mounted on the ground. The controller is connected with a computer.Type: GrantFiled: July 22, 2022Date of Patent: January 14, 2025Assignee: NORTHEASTERN UNIVERSITYInventors: Xiating Feng, Xiwei Zhang, Lei Shi, Zhibin Yao
-
Publication number: 20250009658Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering an effective amount of a pharmaceutical composition including a PUFA-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system to a subject in need of treatment, and treating cancer. A method of overcoming multidrug resistance by exposing a multidrug resistant cell to an effective amount of a pharmaceutical composition including an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system, and inducing the death of the multidrug resistant cell. A method of eliminating a cancer stem cell. Methods of reducing stemness of a cancer stem cell, retaining drug in the body, and providing a slower release profile.Type: ApplicationFiled: July 16, 2024Publication date: January 9, 2025Applicants: TargaGenix, Inc., Research Foundation for State University New York, Northeastern UniversityInventors: James E. EGAN, Iwao OJIMA, Mansoor M. AMIJI, Galina Ivanovna BOTCHKINA
-
Patent number: 12191656Abstract: The presently disclosed embodiments generally relate to systems, devices, and methods for sensing and charging of electronic devices using coils. In some embodiments, the presently disclosed system can include a pad, a charging foot, and a backpack. The pad can include one or more nested coils therein that can sense one or more corresponding receiver coils of an unmanned aerial vehicles (UAV) that landed thereon. The nested coils of the pad can provide charging energy to the UAV independent of the location along the pad in which the UAV landed, and no precise alignment between the receiver coils and the charging coils is required. The charging foot can be attached to one or more legs of the UAV, and can include a receiver coil and circuitry to regulate energy received by the coil to a charging voltage level that can be provided to the battery.Type: GrantFiled: September 28, 2022Date of Patent: January 7, 2025Assignee: Northeastern UniversityInventors: Yousof Naderi, Kaushik Chowdhury
-
Patent number: 12192792Abstract: A self-optimizing operating system for next-generation cellular networks is provided. The system provides telecommunications operators with an efficient and flexible network control platform that hides low-level network details through a virtual network abstraction and allows them to define centralized and high-level control objectives with no need for in-depth and detailed knowledge of cross-layer optimization theory or the underlying wireless protocol stack implementation.Type: GrantFiled: May 1, 2020Date of Patent: January 7, 2025Assignee: Northeastern UniversityInventors: Tommaso Melodia, Leonardo Bonati, Salvatore D'Oro
-
Patent number: 12187834Abstract: Disclosed herein are hydrogel compositions comprising a triblock copolymer having a formula A-B-A, wherein A is a polycaprolactone (PCL) block or a polyvalerolactone (PVL) block and B is a polyethylene glycol (PEG) block. Also disclosed are methods of making a hydrogel comprising providing a photoinitiator and a triblock copolymer having a formula A-B-A, wherein the triblock copolymer comprises one or more ethylenically unsaturated moieties; and photocrosslinking the triblock copolymer, thereby forming a hydrogel.Type: GrantFiled: December 13, 2023Date of Patent: January 7, 2025Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, NORTHEASTERN UNIVERSITYInventors: Yi Hong, Guohao Dai, Cancan Xu, Wen-han Lee
-
Patent number: 12186428Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer.Type: GrantFiled: November 14, 2022Date of Patent: January 7, 2025Assignees: TargaGenix, Inc., The Research Foundation for the State University of New York, Northeastern UniversityInventors: James E. Egan, Mansoor M. Amiji, Iwao Ojima
-
Patent number: 12188338Abstract: A microwave drill bit capable of achieving fracturing of a borehole wall and end of a deep hard rock while drilling and a use method thereof are provided. The microwave drill bit comprises a microwave drill bit body, wherein a support frame front plate, a metal sleeve and a water inlet ring sequentially sleeve on the microwave drill bit body, the metal sleeve is connected with a rotary drive I mounted on the support frame front plate, the microwave drill body is connected with a microwave mode converter and a microwave splitter II respectively, the microwave mode converter and the microwave splitter II are connected with a microwave splitter I by a rectangular waveguide, the microwave splitter I is sequentially connected with a microwave rotating joint, a fixed waveguide and a microwave generator, and the microwave rotating joint is connected with a rotary drive II mounted on the support frame rear plate.Type: GrantFiled: April 21, 2023Date of Patent: January 7, 2025Assignee: NORTHEASTERN UNIVERSITYInventors: Feng Lin, Xiating Feng, Chengxiang Yang, Jiuyu Zhang, Shiping Li, Tianyang Tong, Xiangxin Su
-
Patent number: 12181440Abstract: Disclosed is a method of desorbing an adsorbed material by subjecting to energy a diazirine adsorbed on a solid surface or a layer on the solid surface, which causes the diazirine to form a carbene and nitrogen gas; and using the energy of the resultant nitrogen gas to desorb the adsorbed material from the solid surface or a layer on the same. Also disclosed is a method of reacting the resultant carbene with (a) a material in the gas phase proximal to the first solid surface; (b) a material adsorbed on a second solid surface proximal to the first solid surface; or (c) a second solid surface proximal to the first solid surface.Type: GrantFiled: August 5, 2022Date of Patent: December 31, 2024Assignee: Northeastern UniversityInventors: Roger W. Giese, Pushkar Kulkarni
-
Patent number: 12178140Abstract: A thin film heterostructure of a topological insulator (TI) with a normal metal (NM) is used as a highly energy efficient and low power dissipation spin Hall Material (SHM). The TI material is sputter deposited onto a substrate and cooled in high vacuum, and an NM material is sputter deposited onto the TI film. The structure and method is compatible with complementary metal oxide (CMOS) processes, and with growth of large-area TI films for wafer-level device fabrication.Type: GrantFiled: December 2, 2021Date of Patent: December 24, 2024Assignee: Northeastern UniversityInventors: Nian-Xiang Sun, Nirjhar Bhattacharjee
-
Patent number: 12171854Abstract: Disclosed are polymers, methods of making polymers, and compositions, focused on cross-linking heterocycles comprising a moiety of Formula I with thiols and thiolates.Type: GrantFiled: March 15, 2022Date of Patent: December 24, 2024Assignee: Northeastern UniversityInventor: Jeffrey N. Agar
-
Patent number: 12176947Abstract: A visible light communication (VLC) system transmits and receives visible light signals across a VLC channel that includes an air-water interface. A transmitter may be configured generates and transmits a visible light signal across the VLC channel to a remote device, and a signal modulator controls the transmitter to generate the visible light signal from a digital transmission signal in accordance with a modulation setting. A receiver processes a remote visible light signal received across the VLC channel from the remote device. A signal demodulator converts the remote visible light signal to a received digital signal.Type: GrantFiled: May 27, 2022Date of Patent: December 24, 2024Assignee: NORTHEASTERN UNIVERSITYInventors: Kerem Enhos, Emrecan Demirors, Tommaso Melodia
-
Patent number: 12177328Abstract: Embodiments protect against memory-based side-channel attacks by efficiently shuffling data. In an example implementation, in response to a data access request by an encryption methodology regarding a first data element from amongst a plurality of data elements stored in memory, a storage address of a second data element of the plurality is determined. This storage address is determined using (i) an address of the first data element in the memory, (ii) a permutation function, and (iii) a random number. In turn, the first data element is stored at the determined storage address of the second data element and the second data element is stored at the address of the first data element. In this way, embodiments protect encryption methodologies from memory-based side-channel attacks.Type: GrantFiled: April 19, 2022Date of Patent: December 24, 2024Assignee: NORTHEASTERN UNIVERSITYInventors: Yunsi Fei, Zhen Jiang
-
Patent number: 12174534Abstract: A scalable printing process capable of printing microscale and nanoscale features for additively manufacturing electronics is provided. This fast, directed assembly-based approach selectively prints microscale and nanoscale features on both rigid and flexible substrates. The printing speed is much faster than state-of-the-art inkjet and flexographic printing, and the resolution is two orders of magnitude higher, with minimum feature size of 100 nm. Feature patterns can be printed over large areas and require no special limitations on the assembled materials. Hydrophilic/hydrophobic patterns are used to direct deposition of nanomaterials to specific regions or to selectively assemble polymer blends to desired sites in a one-step process with high specificity and selectively. The selective deposition can be based on electrostatic forces, hydrogen bonding, or hydrophobic interactions.Type: GrantFiled: October 16, 2020Date of Patent: December 24, 2024Assignee: Northeastern UniversityInventors: Salman A. Abbasi, Zhimin Chai, Ahmed Busnaina
-
Patent number: 12169145Abstract: Zero-power system for remote monitoring of heat sources is provided. The systems detect failure indicators of remote equipment including power substations, oil rigs, large inaccessible machinery in a factory, and communications equipment. The systems also can be used to detect the presence of people in buildings or in other locations, so as to improve HVAC utilization in large buildings. When the zero-power monitoring systems detect heat sources, such as the presence of people, failure indicators, or a targeted environmental signal, a circuit is closed using the energy of the detected radiation, and activating an RFID tag, a radio transmitter, or an alarm. The monitoring systems can remain deployed and active for many years without the need for battery replacement.Type: GrantFiled: January 21, 2020Date of Patent: December 17, 2024Assignee: Northeastern UniversityInventors: Matteo Rinaldi, Zhenyun Qian, Vageeswar Rajaram, Sungho Kang
-
Patent number: 12157901Abstract: Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.Type: GrantFiled: December 5, 2022Date of Patent: December 3, 2024Assignee: Northeastern UniversityInventors: Shashi K. Murthy, Bradley B. Collier