Abstract: A method and apparatus for producing a composite part are provided to enable composite parts to be assembled with precise control over the orientation and spatial distribution of reinforcing or other particles within a matrix material. The method and apparatus use magnetic fields applied during various additive manufacturing processes to achieve complex particles orientations within each layer of the part. The composite parts can achieve enhanced properties, including mechanical, thermal, electrical and optical properties.

Abstract: Provided in one embodiment is filtering article, comprising: powders comprising bundles of nanotubes, each bundle comprising hollow titania nanotubes. Embodiments of the methods of making and using the filtering articles are also provided.

Abstract: A system for sensing a target in a region of interest (ROI) includes a coded compressive antenna (CCA) to generate an EM field codified in multiple dimensions. One or more receivers receives EM energy reflected by the target, and produces reflection information corresponding to the reflected energy. A compressive sensing imaging processor analyzes reflection information to generate an image representing the target. The CCA may use a distorted reflector, a vortex lens, and/or meta-materials to codify the EM field in multiple dimensions. The system may evaluate a sensing matrix that characterizes the transmission channel and the codified EM field. The system configures the CCA to produce a coded EM field enhances certain sensing matrix singular values, with respect to an EM field produced by a non-codified antenna. The sensing system provides increased target sensitivity while reducing false detections.

Abstract: A large-scale three-dimensional physical model test system for a deep cavern group comprises a base, an anti-deformation prestressed loading frame assembly, a load applying assembly, a model sample preparation and transportation assembly and a multifunctional hydraulic loading system assembly. The anti-deformation prestressed loading frame assembly and the model sample preparation and transportation assembly are both arranged on the base. The load applying assembly is arranged on the anti-deformation prestressed loading frame assembly, and the load applying assembly is connected with the multifunctional hydraulic loading system assembly. A model sample is subjected to long-time load holding, dynamic disturbance and displacement control overload under multi-surface multi-point cooperative control through cooperation between the load applying assembly and the multifunctional hydraulic loading system assembly.

Abstract: Disclosed herein are compounds represented by Structural Formula I: or a pharmaceutically acceptable salt thereof. Values for the variables in Structural Formula I are described herein. The compounds can be used to modulate (e.g., inhibit) N-acylethanolamine hydrolyzing acid amidase (NAAA) and thereby treat a variety of diseases, disorders and conditions mediated by NAAA, such as a gastrointestinal motility disorder, irritable bowel syndrome, an inflammatory bowel disorder, neuroinflammation, nicotine addiction, cancer, opioid dependence, analgesia, chemotherapy-induced neuropathic pain and pain. Also disclosed herein are compositions and methods including compounds of Structural Formula I, or a pharmaceutically acceptable salt thereof.

Abstract: A method for calorimetry includes flowing a first fluid through a co-flow reactor microchannel having plural inlets and an outlet, the first fluid flowing through each of the inlets, and measuring transmission of light through a Nano Hole Array (NHA) sensor to obtain a baseline extraordinary optical transmission (EOT) measurement. The flow of the first fluid is stopped, the microchannel is emptied of the first fluid, and the first fluid and a second fluid are passed through the microchannel such that a reaction occurs, the first fluid flowing through a first of the inlets and the second fluid flowing through a second of the inlets. While flowing the first and second fluids, transmission of light through the NHA sensor is measured to obtain a reaction EOT measurement. A calorimetry measurement, indicative of energy released during the reaction, is calculated as a function of the baseline and reaction EOT measurements.

Abstract: The use of magnetic fields in the production of porous articles is generally described. Certain embodiments are related to methods of producing porous articles in which magnetic fields are applied to an emulsion to align emulsion droplets. In some embodiments, after the emulsion droplets have been aligned, the emulsion droplets and/or the medium surrounding the emulsion droplets can be removed to leave behind a porous article. According to certain embodiments, polyvinyl alcohol can be used, for example, to stabilize the emulsion droplets and/or bind together components of the porous article. In some embodiments, water-soluble liquid alcohol can be used, for example, to stabilize the suspension of electronically conductive material within a phase of the emulsion.

Abstract: A microelectromechanical resonant circulator device is providing, having a substrate, and at least three electrical ports supported on the substrate. At least three electromechanical resonator elements are connected with associated switch elements and an associated port. The switch elements are operative to provide commutation over time of the electromechanical resonator elements.

Abstract: Methods, systems, and devices described herein enable single-image optical sectioning, even at depth within turbid media, such as human skin or other tissue. Embodiments can eliminate the need for multiple image samples or raster scans, making in-vivo or live biological imaging easier and faster than multi-image sectioning techniques. Better contrast and resolution than traditional three-phase structured illumination microscopy (SIM) is possible in turbid media. Embodiments enable imaging of cell nuclei. Resolution and contrast resulting from disclosed embodiments are less sensitive to motion of or within patients or other targets than confocal microscopy and three-phase SIM techniques. Three-dimensional images of target specimens can be provided based on a group of single-image optical sections. Real-time imaging can also be provided.

Abstract: A method and system for providing a recovery sequence for a network from a state of disruption to a state of partial or complete functionality are provided. The method and system can measure the response of a network to one or multiple hazards and can generate and compare the effectiveness of multiple recovery strategies in a quantitative and generalizable manner, providing a user with practical tools to implement an efficient restoration of the network.

Abstract: Embodiments are directed to a platform for liquid droplet generation and isolation for biochemical sensing and testing. An embodiment includes generator, fluid-exchange, and manipulator structures that are vertically aligned on a substrate to form a collection chamber. The generator structure is configured to form liquid droplets from a stream of liquid using gas. The fluid-exchange structure is connected to the generator structure to receive the liquid droplets in a carrier liquid held in the collection chamber. The manipulator structure is connected to receive the liquid droplets in the carrier liquid via an inlet. The manipulator structure defines a manipulator chamber connected to the inlet and has a first outlet and a second outlet and a filter capable of filtering the liquid droplets from the carrier liquid. The first outlet enables removal of the liquid droplets filtered and the second outlet enables removal of the carrier liquid.

Abstract: Inter-allotropic transformations of carbon are provided using moderate conditions including alternating voltage pulses and modest temperature elevation. By controlling the pulse magnitude, small-diameter single-walled carbon nanotubes are transformed into larger-diameter single-walled carbon nanotubes, multi-walled carbon nanotubes of different morphologies, and multi-layered graphene nanoribbons.

Abstract: Bonded surfaces are formed by adhering first nanorods and second nanorods to respective first and second surfaces. The first shell is formed on the first nanorods and the second shell is formed on the second nanorods, wherein at least one of the first nanorods and second nanorods, and the first shell and the second shell are formed of distinct metals. The surfaces are then exposed to at least one condition that causes the distinct metals to form an alloy, such as eutectic alloy having a melting point below the temperature at which the alloy is formed, thereby bonding the surfaces upon which solidification of the alloy.

Abstract: A compound is represented as Formula I, a tautomer thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof: Compounds of Formula I are inhibitors of N-acylethanolamine hydrolyzing acid amidase (NAAA).

Abstract: A zero-power plasmonic microelectromechanical system (MEMS) device is capable of specifically sensing electromagnetic radiation and performing signal processing operations. Such devices are highly sensitive relays that consume no more than 10 nW of power, utilizing the energy in detected electromagnetic radiation to detect and discriminate a target without the need of any additional power source. The devices can continuously monitor an environment and wake up an electronic circuit upon detection of a specific trigger signature of electromagnetic radiation, such as vehicular exhaust, gunfire, an explosion, a fire, a human or animal, and a variety of sources of radiation from the ultraviolet to visible light, to infrared, to terahertz radiation.

Abstract: Nanofluidic devices and methods of the invention are capable of autonomously isolating individual microbial cells using constrictive channels and growing monocultures of the cells for automated characterization of their biochemical properties and interactions with mammalian cells. Single microbial cells, such as bacterial cells, are isolated directly from environmental sources and cultured using chemical factors from their native environment.

Abstract: Provided is a disc gap servo control device and method for a powder grinding system, which includes a disc powder grinding machine, a rotating speed regulating device of a rotating disc, the disc gap servo control device and a control cabinet. The method includes the following steps of: (1) inputting a control information; (2) an industrial computer obtaining a current disc gap and displaying the disc gap on a touch screen; (3) the disc gap servo control device adjusting the disc gap; (4) the current disc gap reaches a target disc gap; and (5) a frequency converter controlling a motor rotating speed, so that the actual rotating disc rotating speed can reach a target rotating speed of the rotating disc. The operation parameters of the rotating disc are observed by the industrial computer in real time, and finally a high-precision servo control of the disc gap can be realized.

Abstract: A sensor and a measurement method for measuring hydrogen content in metal melt. The sensor has a solid proton conductor element, a reference electrode, a quasi-electrode to be measured, a reference compound, a through pipe and an insulating ceramic adhesive. The measurement method has the steps of: (1) inserting the sensor and a corrosion-resistant electrode into the metal melt, and making sure that the solid proton conductor element is fully immersed into the metal melt, the quasi-electrode to be measured is in direct contact with the metal melt and the contact surface is the electrode to be measured; (2) connecting a potentiometer and the reference electrode cable or the metal gas guide pipe to the corrosion-resistant electrode, and measuring a potential difference between the reference electrode and the electrode to be measured; and (3) calculating the hydrogen content S of the metal melt.

Abstract: Augmented three-dimensional (3D) printing systems and methods for constructing and mineralizing a hydrogel structure with defined geometry are disclosed. One example embodiment is a system for three-dimensional printing and mineralizing a polymer. The system includes a three-dimensional printer unit with a syringe extruder, a fluid delivery system operatively coupled to the three-dimensional printer unit, and a control unit. The control unit is operatively coupled to the three-dimensional printer unit and fluid delivery system, and is configured to (i) cause the three-dimensional printer unit to print a portion of a three-dimensional polymer object, (ii) cause the fluid delivery system to flush the portion of the three-dimensional polymer object with a fluid to mineralize the portion of the three-dimensional polymer object, and (iii) cause the three-dimensional printer unit to print a subsequent portion of the three-dimensional polymer object.

Abstract: The disclosed subject matter relates to brush polymer-oligonucleotide conjugates comprising oligonucleotides covalently attached to the backbone of a non-cationic, sterically congested brush polymer and the use of such polymer-oligonucleotide conjugates in antisense gene regulation and as diagnostic agents.