Patents Assigned to Northeastern University
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Patent number: 10834854Abstract: In an embodiment, a process for making a thermal interface article comprises shaping a flowable composite comprising a flowable matrix composition, a plurality of magnetic, thermally conductive particles having an average length greater than a thickness or diameter, wherein the plurality of magnetic, thermally conductive particles have magnetic or superparamagnetic nanoparticles attached thereto, to provide the flowable composite in a shape comprising a first surface and an opposing second surface, and having a Z-axis perpendicular to the first surface and the opposing second surface; subjecting the flowable composite to a rotating magnetic field and to a vibrational force in an amount and for a time effective to align the average length of the plurality of magnetic, thermally conductive particles along the Z-axis; and solidifying the flowable matrix composition to provide the thermal interface, wherein the thermal interface has a Z-direction thermal conductivity of at least 1.0 W/mK.Type: GrantFiled: February 12, 2018Date of Patent: November 10, 2020Assignee: Northeastern UniversityInventors: Li Zhang, Randall Morgan Erb, Jabulani R. T. Barber, Anvesh Gurijala, Qiaochu Han
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Patent number: 10825219Abstract: Embodiments provide methods and systems for image generation through use of adversarial networks. An embodiment trains an image generator comprising (i) a generator implemented with a first neural network configured to generate a fake image based on a target segmentation, (ii) a discriminator implemented with a second neural network configured to distinguish a real image from a fake image and output a discrimination result as a function thereof and (iii) a segmentor implemented with a third neural network configured to generate a segmentation from the fake image. The training includes (i) operating the generator to output the fake image to the discriminator and the segmentor and (ii) iteratively operating the generator, discriminator, and segmentor during a training period, whereby the discriminator and generator train in an adversarial relationship with each other and the generator and segmentor train in a collaborative relationship with each other.Type: GrantFiled: March 22, 2019Date of Patent: November 3, 2020Assignee: Northeastern UniversityInventors: Yun Fu, Songyao Jiang
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Patent number: 10815582Abstract: Damascene templates have two-dimensionally patterned raised metal features disposed on an underlying conductive layer extending across a substrate. The templates are topographically flat overall, and the patterned conductive features establish micron-scale and nanometer-scale patterns for the assembly of nanoelements into nanoscale circuits and sensors. The templates are made using microfabrication techniques together with chemical mechanical polishing. These templates are compatible with various directed assembly techniques, including electrophoresis, and offer essentially 100% efficient assembly and transfer of nanoelements in a continuous operation cycle. The templates can be repeatedly used for transfer of patterned nanoelements thousands of times with minimal or no damage, and the transfer process involves no intermediate processes between cycles. The assembly and transfer processes employed are carried out at room temperature and pressure and are thus amenable to low cost, high-rate device production.Type: GrantFiled: January 9, 2019Date of Patent: October 27, 2020Assignee: Northeastern UniversityInventors: Ahmed Busnaina, Hanchul Cho, Sivasubramanian Somu, Jun Huang
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Patent number: 10818952Abstract: Lignin-based electrolytes and flow battery cells and systems for use with lignin-based electrolytes are disclosed.Type: GrantFiled: November 29, 2018Date of Patent: October 27, 2020Assignee: Northeastern UniversityInventors: Hongli Zhu, Jonathan Hamel
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Patent number: 10812365Abstract: Network architectures and methods including addressing and dynamic network topology construction schemes that guarantee maximally efficient and scalable routing are disclosed herein. The network architectures and methods introduce a new approach to network design. The network architectures and methods include an addressing scheme based on geographic position of network nodes, and a network topology construction scheme based on the addressing scheme and that can reproduce properties of the existing Internet topology. A routing algorithm for the network architecture is shown to be maximally scalable and efficient. According to an example embodiment, a network includes a plurality of nodes, where each node has a network address based on a latitude of a location of the node, a longitude of the location of the node, and a centrality of the location of the node.Type: GrantFiled: November 16, 2017Date of Patent: October 20, 2020Assignee: Northeastern UniversityInventors: Dmitri Krioukov, Ivan Voitalov
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Patent number: 10802016Abstract: Platform technology involving aqueous microdroplet reaction vessels created, arrayed, and characterized by imaging microscopy in a microfluidic device are applied to a wide variety of bioassays involving the detection and phenotypic characterization of single cells. The bioassays include the rapid and automated detection of microbial pathogens and their antibiotic sensitivity from patient samples as well as the characterization of immune responses using a patient's own cells, including the killing of tumor cells.Type: GrantFiled: September 10, 2019Date of Patent: October 13, 2020Assignee: Northeastern UniversityInventors: Tania Konry, Pooja Sabhachandani, Saheli Sarkar
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Patent number: 10799604Abstract: A method of detecting migration of tumor cells is provided by implanting in a region of tumor cells one or more implants having a matrix material of a biocompatible and biodegradable polymer, and a plurality of nanoparticles dispersed within the matrix material and functionalized to bind tumor cells. Nanoparticles bound to the tumor cells that have migrated out of the region can be detected by various imaging modalities. The implant can be in the shape of a brachytherapy spacer or radiotherapy fiducial maker or can be a coating on a brachytherapy spacer or fiducial marker. A method of treating cancer is provided by implanting one or more brachytherapy spacers or fiducial markers including the matrix material and an anti-cancer therapeutic agent dispersed within the matrix material.Type: GrantFiled: July 27, 2015Date of Patent: October 13, 2020Assignees: Northeastern University, Dana-Farber Cancer Institute, Inc., The Brigham and Women's Hospital, Inc.Inventors: Rajiv Kumar, Srinivas Sridhar, Wilfred Ngwa, Robert Cormack, Gerassimos Makrigiorgos
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Patent number: 10797537Abstract: A distributed wireless radio frequency-based charging system includes hardware and software platforms. The hardware platform includes adaptive energy harvesters and programmable energy transmitters. The software platform manages the hardware profiles, resources (e.g., energy waveforms and transmission powers), schedules the beams of the energy transmitters, and switches between modes of wireless charging and data access point. This allows the energy transmitters to be configured adaptively based on the ambient energy availability, energy needs and number of energy-requesting devices in the network. Under the software control, the energy transmitters can cooperatively form focused beams of energy and power for transmission to energy harvesters in the energy-receiving devices, such as sensors, Internet of Things (IoT) enabled appliances, and mobile/wearable equipment.Type: GrantFiled: March 13, 2017Date of Patent: October 6, 2020Assignee: Northeastern UniversityInventors: Kaushik Chowdhury, M. Yousof Naderi
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Patent number: 10793891Abstract: Nanofluidic devices and methods of the invention are capable of autonomously isolating individual microbial cells using constrictive channels and growing monocultures of the cells for automated characterization of their biochemical properties and interactions with mammalian cells. Single microbial cells, such as bacterial cells, are isolated directly from environmental sources and cultured using chemical factors from their native environment.Type: GrantFiled: August 22, 2017Date of Patent: October 6, 2020Assignee: Northeastern UniversityInventor: Slava Epstein
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Publication number: 20200308722Abstract: A method for transforming a crystal form of an electrolyte containing lithium for aluminum electrolysis includes the following steps: S1, pulverizing the electrolyte containing lithium; S2, uniformly mixing an additive with the electrolyte powder to obtain a mixture, wherein the additive is one or more selected from the group consisting of an oxide of an alkali metal other than lithium, an oxo acid salt of an alkali metal other than lithium, and a halide of an alkali metal other than lithium; a molar ratio of a sum of alkali metal fluoride contained in the electrolyte, alkali metal fluoride directly added from the additive, and alkali metal fluoride to which the additive is converted under the high-temperature calcination condition in the mixture to aluminum fluoride is greater than 3; S3, calcining the mixture at a high temperature.Type: ApplicationFiled: May 17, 2018Publication date: October 1, 2020Applicant: NORTHEASTERN UNIVERSITYInventors: Zhaowen WANG, Wenju TAO, Youjian YANG, Bingliang GAO, Fengguo LIU
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Patent number: 10790946Abstract: A system and method for transmitting data ultrasonically through biological tissue employs a network of a plurality of nodes, at least a portion of the nodes implantable within the biological tissue. At least one implanted node includes a transmitter having an orthogonal frequency division multiplex signal generator to encode an ultrasonic signal for transmission through the biological tissue to an ultrasonic receiver at another node.Type: GrantFiled: August 27, 2019Date of Patent: September 29, 2020Assignee: Northeastern UniversityInventors: Tommaso Melodia, Giuseppe Enrico Santagati
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Patent number: 10784970Abstract: Embodiments disclosed herein may be implemented in the form of a method or corresponding apparatus for receiving or transmitting network communications carried at acoustic wavelengths via an acoustic medium. The corresponding method or apparatus may include a gate-level digital hardware module communicatively coupled to a communications module and define therein logic blocks configured to perform respective primitive processing functions, sequences of the logic blocks being capable of processing data units in accordance with any of the multiple communications protocols on a data unit-by-data unit basis without reconfiguring.Type: GrantFiled: October 23, 2017Date of Patent: September 22, 2020Assignee: Northeastern UniversityInventors: Tommaso Melodia, Emrecan Demirors
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Patent number: 10784518Abstract: The invention provides a nitrogen-functionalized platinum-transition metal catalyst having the formula Pt-M-NX/C (where M is a transition element such as Fe, Co, Ni, Nb, Ta, Ir, Rh, or Ru) for use at the hydrogen electrode of a hydrogen/bromine redox flow battery. The new catalyst possesses excellent activity and durability in the HBr/Br2 environment, showing superior resistance to halide poisoning than conventional Pt/C or Pt-M/C catalysts.Type: GrantFiled: May 12, 2016Date of Patent: September 22, 2020Assignee: Northeastern UniversityInventors: Sanjeev Mukerjee, Michael Bates, Shraboni Ghoshal, Huong Thi Thanh Doan
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Patent number: 10732139Abstract: A glucose sensor suitable for measuring glucose levels in human saliva is provided. Systems containing the glucose sensor and methods for making and using the sensor are also provided. The glucose sensor is highly sensitive and can detect glucose levels at least down to 5 ppm. Fabrication of the sensor involves depositing single-walled carbon nanotubes onto the surface of a working electrode in a 3 electrode electrochemical detector and functionalizing the nanotubes by depositing layers of polymers, metallic nanoparticles, and glucose oxidase enzyme onto the nanotubes. The sensor can be used as a disposable, single-use device or as part of an analytical system, such as a microfluidics system, for the analysis of multiple analytes. The sensor enables the diagnosis and monitoring of diabetes to be performed without pain or the need for finger pricks in a home or clinical setting.Type: GrantFiled: December 14, 2015Date of Patent: August 4, 2020Assignee: Northeastern UniversityInventors: Wenjun Zhang, Ming L. Wang
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Patent number: 10731131Abstract: Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.Type: GrantFiled: June 29, 2016Date of Patent: August 4, 2020Assignee: NORTHEASTERN UNIVERSITYInventors: Shashi K. Murthy, Bradley B. Collier
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Patent number: 10734951Abstract: A receiver circuit receives a signal from a semiconductor device. The receiver circuit includes an input buffer including a first plurality of transistors, the input buffer being configured to detect a fabrication condition of the receiver circuit, generate a control signal according to the detected fabrication condition, and control a gain of an input signal by adjusting a number of operating transistors among the first plurality of transistors in response to the control signal; and a latch circuit configured to latch an output signal of the input buffer, and adjust threshold voltages of a second plurality of transistors in response to a test signal.Type: GrantFiled: April 4, 2018Date of Patent: August 4, 2020Assignees: SK hynix Inc., NORTHEASTERN UNIVERSITYInventors: Hae Kang Jung, Yong Suk Choi, Yong Bin Kim, Gyunam Jeon, Dae-Han Kwon, Joo Hwan Cho
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Patent number: 10726601Abstract: A system and method are provided to detect, analyze and digitally remove makeup from an image of a face. An autoencoder-based framework is provided to extract attractiveness-aware features to perform an assessment of facial beauty.Type: GrantFiled: May 17, 2019Date of Patent: July 28, 2020Assignee: Northeastern UniversityInventors: Yun Fu, Shuyang Wang
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Patent number: 10718763Abstract: Platform technology involving aqueous microdroplet reaction vessels created, arrayed, and characterized by imaging microscopy in a microfluidic device are applied to a wide variety of bioassays involving the detection and phenotypic characterization of single cells. The bioassays include the rapid and automated detection of microbial pathogens and their antibiotic sensitivity from patient samples as well as the characterization of immune responses using a patient's own cells, including the killing of tumor cells.Type: GrantFiled: July 15, 2016Date of Patent: July 21, 2020Assignee: Northeastern UniversityInventors: Tania Konry, Pooja Sabhachandani, Saheli Sarkar
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Patent number: 10720564Abstract: Compact and power efficient acoustically actuated magnetoelectric antennas for transmitting and receiving very low frequency (VLF) electromagnetic waves utilize magnetoelectric coupling in a magnetic/piezoelectric heterostructure to provide voltage control of magnetization in transmission mode and magnetic control of electric polarization in receiving mode. The magnetoelectric antennas provide a power efficiency enhanced by orders of magnitude compared to magnetically or mechanically switching the magnetization. The antennas can be used in groups or arrays and can be combined to form VLF communication systems.Type: GrantFiled: October 25, 2017Date of Patent: July 21, 2020Assignee: Northeastern UniversityInventors: Nian Xiang Sun, Menghui Li
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Patent number: 10713399Abstract: Provided is a method of batching and scheduling for steelmaking production with plant-wide process consideration, including the steps of: establishing a mathematical model for quantitatively describing the decision problem of batching on steelmaking and continuous casting procedures; starting from the production capacity balance between parallel equipment of the same procedure, and material flow convergence between upstream and downstream procedures, establishing a model for the assignment and sequencing of batches on continuous casting equipment and the time dimension; integrating the batching plan and the production scheduling scheme, issuing the batching plan and the production scheduling scheme integrated to all production and manufacturing units at the steelmaking stage.Type: GrantFiled: November 14, 2016Date of Patent: July 14, 2020Assignee: NORTHEASTERN UNIVERSITYInventors: Li xin Tang, Gong shu Wang, Wen jie Xu