Patents Assigned to Northwestern University
  • Patent number: 10703637
    Abstract: A boron allotrope comprising an elemental boron layer comprising a boron atomic thickness dimension and a method for preparation thereof.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: July 7, 2020
    Assignees: NORTHWESTERN UNIVERSITY, UCHICAGO ARGONNE, LLC
    Inventors: Mark C. Hersam, Joshua D. Wood, Andrew J. Mannix, Brian T. Kiraly, Brandon L. Fisher, Nathan P. Guisinger
  • Patent number: 10705611
    Abstract: This disclosure provides designer interfaces that present condensed representations of texture functions, the representations displaying selected control points that manipulate the representations, an algorithm that computes a texture function based on the positions of said selected control points, and the texture function generating a signal to control a force on an appendage of a user that touches a tactile surface, and methods of using the designer interfaces.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: July 7, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventor: David J. Meyer
  • Patent number: 10705589
    Abstract: A system includes an ARM core processor, a programmable regulator, a compiler, and a control unit, where the compiler uses a performance association outcome to generate a 2-bit regulator control values encoded into each individual instruction. The system can provide associative low power operation where instructions govern the operation of on-chip regulators or clock generator in real time. Based on explicit association between long delay instruction patterns and hardware performance, an instruction based power management scheme with energy models are formulated for deriving the energy efficiency of the associative operation. An integrated voltage regulator or clock generator is dynamically controlled based on instructions existing in the current pipeline stages leading to additional power saving. A compiler optimization strategy can further improve the energy efficiency.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: July 7, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Jie Gu, Russ Joseph
  • Patent number: 10702803
    Abstract: Separation of rhenium disulfide nanomaterials and related fluid density gradient media.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: July 7, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Mark C. Hersam, Joohoon Kang
  • Patent number: 10705610
    Abstract: A touch interface device that produces tactile and audio output comprising a touch surface, an first electrode coupled to the touch surface that receives a first haptic/audio output potential, a second electrode coupled to a low impedance return path to the device, the first and second electrodes being configured such that when both the first and second electrodes are touched by an appendage of a user, a current flows between the first and second electrodes and the appendage, where the current creates an electric field that imparts a controlled electrostatic force at interfaces of the first electrode and the appendage, and wherein the electrostatic force provides tactile feedback to the appendage of the user and causes vibration in the surrounding air that is audible to the user.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: July 7, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: James E. Colgate, Michael A. Peshkin, Craig Shultz
  • Publication number: 20200199576
    Abstract: Disclosed herein are compounds, compositions, and methods for identifying substrates of E3 ubiquitin ligases. The proteins, vectors, compositions, and may be utilized in methods for orthogonal ubiquitin transfer (OUT) between variant components of the ubiquitin cascade such as a variant ubiquitin (UB), a variant ubiquitin activating enzyme (E1), a variant ubiquitin-conjugating enzyme (E2), and a variant ubiquitin ligase (E3), which may include a variant HECT type, U-box type, RBR type, and/or Ring type E3 ligase. The variant components of the ubiquitin cascade typically include one or more mutations relative to their wild-type counterparts, such as amino acid substitutions, such that the variant components interact specifically and orthogonally with each of their variant components and do not interact with the wild-type counterpart of their variant components.
    Type: Application
    Filed: December 19, 2019
    Publication date: June 25, 2020
    Applicants: Northwestern University, Georgia State University Research Foundation
    Inventors: Jun Yin, Hiroaki Kiyokawa, Yiyang Wang, Karan Bhuripanyo, Bo Zhao, Xianpeng Liu, Li Zhao
  • Patent number: 10694123
    Abstract: A method for imaging objects includes illuminating an object with a light source of an imaging device, and receiving an illumination field reflected by the object. An aperture field that intercepts a pupil of the imaging device is an optical propagation of the illumination field at an aperture plane. The method includes receiving a portion of the aperture field onto a camera sensor, and receiving a sensor field of optical intensity. The method also includes iteratively centering the camera focus along the Fourier plane at different locations to produce a series of sensor fields and stitching together the sensor fields in the Fourier domain to generate an image. The method also includes determining a plurality of phase information for each sensor field in the series of sensor fields, applying the plurality of phase information to the image, receiving a plurality of illumination fields reflected by the object, and denoising the intensity of plurality of illumination fields using Fourier ptychography.
    Type: Grant
    Filed: July 14, 2018
    Date of Patent: June 23, 2020
    Assignees: Northwestern University, William Marsh Rice University
    Inventors: Oliver Strider Cossairt, Jason Holloway, Ashok Veeraraghavan, Manoj Kumar Sharma, Yicheng Wu
  • Patent number: 10692700
    Abstract: A system for laser-induced plasma micromachining of a work-piece includes a dielectric fluid, a dielectric fluid supply device, a laser, a processor, and a memory. The dielectric fluid supply device is arranged to hold a work-piece in the dielectric fluid or to direct the dielectric fluid onto the work-piece. The laser is arranged to emit a pulsed laser-beam. The processor is in electronic communication with the laser. The memory is in electronic communication with the processor. The memory includes programming code for execution by the processor. The programming code is programmed to direct the laser to deliver the pulsed laser-beam into the dielectric fluid to create a plasma generated at a focal point of the pulsed laser-beam in the dielectric fluid to micromachine, using the plasma, the work-piece disposed adjacent to the focal point.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: June 23, 2020
    Assignee: Northwestern University
    Inventors: Kumar Pallav, Rajiv Malhotra, Ishan Saxena, Kornel Ehmann, Jian Cao
  • Patent number: 10690661
    Abstract: Provided herein are compositions and systems comprising yeast-based biosensors (YBBs) and methods of use thereof. In particular, YBBs are provided for the detection and/or quantification of an analyte (e.g., peptide analyte) in a sample (e.g., a biological sample, environmental sample, etc.). In some embodiments, provided herein are diagnostic compositions, devices, and methods comprising yeast-based biosensors (YBBs) engineered to detect analytes (e.g., peptides (e.g., biomarker peptides, etc.), etc.). In some embodiments, YBBs comprise (a) recognition element (e.g., receptor (e.g., modified yeast receptor, etc.), etc.) on the exterior of the biosensor (e.g., for binding and or recognition of the analyte (e.g., peptide)), and (b) a reporter that signals binding or recognition of the analyte. In some embodiments, a recognition element is a cell surface receptor.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: June 23, 2020
    Assignee: Northwestern University
    Inventors: Keith E. J. Tyo, Adebola V. Adeniran, John W. Bostick, Dante A. Pertusi, Sarah Christine Stainbrook
  • Patent number: 10689252
    Abstract: The present teachings provide methods for providing populations of single-walled carbon nanotubes that are substantially monodisperse in terms of diameter, electronic type, and/or chirality. Also provided are single-walled carbon nanotube populations provided thereby and articles of manufacture including such populations.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: June 23, 2020
    Assignee: Northwestern University
    Inventors: Michael S. Arnold, Mark C. Hersam, Samuel I. Stupp
  • Patent number: 10688195
    Abstract: Provided herein are antibiotic coated nanoparticles and methods of treating bacterial infection therewith. In particular embodiments, polymyxin B, vancomycin, and/or other antibiotics are linked to nanoparticles (e.g., gold or silica nanoparticles) and utilized for the treatment of bacterial infections.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: June 23, 2020
    Assignees: NORTHWESTERN UNIVERSITY, MIDWESTERN UNIVERSITY
    Inventors: Alan R. Hauser, Andrew Lee, Marc H. Scheetz, Nathaniel J. Rhodes
  • Publication number: 20200188974
    Abstract: A rolling mill system for Incremental rotary shaping of an elongated workpiece is provided that includes first and second workpiece holders. A support frame has a track with the first and second workpiece holders being movably associated with the track, the workpiece holders and an associated workpiece being movable in unison along the track. A radial chuck is mounted to the frame that includes a plurality of jaws that are movable radially inwardly and outwardly. Each jaw has a tool mounted thereto that is rotatable about an axis of rotation, with the axis of rotation of each tool being oriented at a skew angle relative to the longitudinal axis of a workpiece. A source of electric current and an electrically conductive flow path are provided for flowing electrical current through a workpiece. A controller is provided that is configured to control the operation of each of the first motor, second motor and third motor, and to control the flow of current flowing through the tools to the workpiece.
    Type: Application
    Filed: October 6, 2017
    Publication date: June 18, 2020
    Applicant: Northwestern University
    Inventors: Qiang Zeng, Kornel Ehmann, Man Kwan Ng, Jian Cao
  • Patent number: 10685181
    Abstract: Disclosed herein are systems, methods and computer readable storage media for determining tags or labels from natural language expressions expressing a preference or choice, determining attributes from natural language expressions and other data, and predicting preferences from natural language expressions and other data.
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: June 16, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Lawrence A. Birnbaum, Shawn O'Banion
  • Patent number: 10684417
    Abstract: Low-coherence enhanced backscattering (LEBS) spectroscopy is an angular resolved backscattering technique that is sensitive to sub-diffusion light transport length scales in which information about the scattering phase function is preserved. Lens-based and lens-free fiber optic LEBS probes are described that are capable of measuring optical properties of a target tissue through depth-limited measurements of backscattering angles within the enhanced backscattered cone.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: June 16, 2020
    Assignees: NORTHWESTERN UNIVERSITY, AMERICAN BIOOPTICS, LLC
    Inventors: Vadim Backman, Jeremy D. Rogers, Nikhil N. Mutyal, Bradley Gould, Andrew J. Radosevich, The Quyen Nguyen
  • Patent number: 10687032
    Abstract: A medicine container includes a controller and a scale connected with the controller. The scale is configured to measure a weight of a content contained in the medicine container. An inertial measurement unit connects with the controller. The inertial measurement unit is configured to detect a position of the medicine container. The controller is configured to process the position information to ensure that the container is located in an upright position before the weight measurement is considered.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: June 16, 2020
    Assignee: Northwestern University
    Inventors: Sanjay Mehrotra, Fatma Seda Memik, Ilya Mikhelson
  • Publication number: 20200179368
    Abstract: Disclosed herein are methods and compositions for administering immunotherapy to a subject in need thereof and for treating a subject in need thereof, where in the methods the subject is administered an effective amount of an inhibitor of nNOS for inducing an immunotherapeutic response in the subject and for treating the subject. The disclosed methods and composition may be utilized for treating a subject having a cell proliferative disease or disorder such as melanoma.
    Type: Application
    Filed: December 4, 2019
    Publication date: June 11, 2020
    Applicants: Northwestern University, Chapman University
    Inventors: Richard B. Silverman, Sun Yang
  • Publication number: 20200181106
    Abstract: Disclosed are enantioselective cross dehydrogenative coupling reactions for synthesizing tetrahydropyran compounds. Novel tetrahydropyran compounds may be synthesized by the disclosed methods as well as tetrahydropyran precursor compounds for synthesizing various naturally occurring compounds. The enantioselective cross dehydrogenative coupling reactions utilize in situ Lewis Acid activation in combination with oxidative formation of an oxocarbenium ion to provide a highly efficient and selective coupling reaction for synthesizing tetrahydropyran compounds.
    Type: Application
    Filed: December 11, 2019
    Publication date: June 11, 2020
    Applicant: Northwestern University
    Inventors: Karl A. Scheidt, Ansoo Lee, Richard C. Betori
  • Patent number: 10676509
    Abstract: Immobilizable antimicrobial compounds incorporating antimicrobial and/or antifouling components, as can be adhered to various device structures and components.
    Type: Grant
    Filed: July 31, 2009
    Date of Patent: June 9, 2020
    Assignee: Northwestern University
    Inventors: Phillip B. Messersmith, Annelise E. Barron, Andrea Statz, Nathaniel Chongslriwatana
  • Patent number: 10676629
    Abstract: A rapid, scalable methodology for graphene dispersion and concentration with a polymer-organic solvent medium, as can be utilized without centrifugation, to enhance graphene concentration.
    Type: Grant
    Filed: December 4, 2017
    Date of Patent: June 9, 2020
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Mark C. Hersam, Yu Teng Liang, Ethan B. Secor, Pradyumna L. Prabhumirashi, Kanan P. Puntambekar, Michael L. Geier
  • Publication number: 20200164317
    Abstract: Methods for making porous polyelectrolyte complex (PEC) films are provided. In an embodiment, such a method comprises coating the surface of a substrate with a polyelectrolyte (PE) coacervate mixture, the PE coacervate mixture comprising a cationic polymer, an anionic polymer, water, and a salt, the PE coacervate having a salt concentration; exposing the coating to an aqueous medium having another salt concentration, for a time to induce solidification of polyelectrolyte complexes (PECs) in the form of a PEC film having pores distributed throughout, wherein a difference ??C-M #191 between the salt concentration of the PE coacervate mixture and the salt concentration of the aqueous medium is selected to achieve a predetermined porosity for the porous PEC film.
    Type: Application
    Filed: May 9, 2018
    Publication date: May 28, 2020
    Applicant: Northwestern University
    Inventors: Kenneth R. SHULL, Kazi SADMAN, Qifeng WANG