Patents Assigned to Prognosys Biosciences, Inc.
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Patent number: 11008607Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: November 13, 2020Date of Patent: May 18, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 11001878Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: January 8, 2021Date of Patent: May 11, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 11001879Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: January 8, 2021Date of Patent: May 11, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Publication number: 20210130884Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: ApplicationFiled: January 8, 2021Publication date: May 6, 2021Applicant: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 10996219Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: June 7, 2019Date of Patent: May 4, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 10983113Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: April 1, 2020Date of Patent: April 20, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 10982268Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: October 30, 2019Date of Patent: April 20, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 10962532Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: March 11, 2020Date of Patent: March 30, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 10961566Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: August 7, 2020Date of Patent: March 30, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 10927403Abstract: The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: August 6, 2020Date of Patent: February 23, 2021Assignee: Prognosys Biosciences, Inc.Inventors: Mark S. Chee, David A. Routenberg
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Patent number: 10914730Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: March 11, 2020Date of Patent: February 9, 2021Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Publication number: 20210017583Abstract: The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature.Type: ApplicationFiled: July 31, 2020Publication date: January 21, 2021Applicant: Prognosys Biosciences, Inc.Inventors: Mark S. CHEE, David A. ROUTENBERG
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Publication number: 20210017586Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: ApplicationFiled: September 25, 2020Publication date: January 21, 2021Applicant: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Publication number: 20210010068Abstract: The present disclosure provides methods and assay systems for use in spatially encoded biological assays, including assays to determine a spatial pattern of abundance, expression, and/or activity of one or more biological targets across multiple sites in a sample. In particular, the biological targets comprise proteins, and the methods and assay systems do not depend on imaging techniques for the spatial information of the targets. The present disclosure provides methods and assay systems capable of high levels of multiplexing where reagents are provided to a biological sample in order to address tag the sites to which reagents are delivered; instrumentation capable of controlled delivery of reagents; and a decoding scheme providing a readout that is digital in nature.Type: ApplicationFiled: August 6, 2020Publication date: January 14, 2021Applicant: Prognosys Biosciences, Inc.Inventors: Mark S. CHEE, David A. ROUTENBERG
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Patent number: 10787701Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: May 16, 2019Date of Patent: September 29, 2020Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Publication number: 20200224256Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: ApplicationFiled: April 1, 2020Publication date: July 16, 2020Applicant: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Publication number: 20200208205Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: ApplicationFiled: March 11, 2020Publication date: July 2, 2020Applicant: Prognosys Biosciences, Inc.Inventor: Mark S. CHEE
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Publication number: 20200208206Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: ApplicationFiled: March 11, 2020Publication date: July 2, 2020Applicant: Prognosys Biosciences, Inc.Inventor: Mark S. CHEE
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Patent number: 10662467Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: February 14, 2019Date of Patent: May 26, 2020Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee
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Patent number: 10662468Abstract: The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.Type: GrantFiled: October 22, 2019Date of Patent: May 26, 2020Assignee: Prognosys Biosciences, Inc.Inventor: Mark S. Chee