Abstract: The present invention provides a polysubstituted pyridine compound of Formula I, a preparation method, a use and a pharmaceutical composition thereof. The polysubstituted pyridine compound of Formula I according to the present invention has an excellent anti-tumor effect, can inhibit various cell kinases simultaneously, has significantly excellent pharmacokinetic characteristics, and is very suitable for oral and intravenous administration. The pharmaceutical composition according to the present invention can be useful for treating tumors and cancers.

Abstract: The invention addresses the problem of providing an edged tool such as a surgical blade or a razor blade that is durable and sharp, and a manufacturing method therefor. The problem is solved by an edged tool manufacturing method provided with a process of treating a metal base material, which has a machined surface obtained by machining, using a plasma generated in an atmosphere filled with a mixed gas having a main gas and a reaction gas as the main components.

Abstract: A retractable suspension system for use with an amphibious vehicle is provided and includes three rotation points disposed on the vehicle body of the vehicle, three integration points disposed on an integration element of a tire, an actuating device and a damping component, so as to render the retractable suspension system structurally simple and multifunctional.

Abstract: One aspect of the invention relates to a method for the purification of cadaverine from an aqueous cadaverine composition comprising one or more involatile impurities, the method comprising: a) distilling or evaporating the aqueous cadaverine composition wherein one or more solvents are added to the evaporation/distillation system before the evaporation/distillation starts, during the evaporation/distillation and/or after the evaporation/distillation substantially stops when no more evaporation/distillation is observed to produce purified cadaverine, wherein the evaporation or distillation is done at a heating temperature of about 80° C. to about 180° C. and under a pressure of 1 atm or lower, and the one or more solvents comprise at least one or more high boiling point (HBP) solvents having a boiling point of at least about 185° C. (1 atm); and b) recovering the one or more HBP solvents.

Abstract: A razor having an attachment portion and a shaving aid is provided. The attachment portion includes a blade body. The shaving aid is provided with a deformable portion that deforms when contacted by the skin surface. When the razor is used, the shaving aid itself deforms to decrease the frictional resistance between the shaving aid and the skin surface. This improves the tactile sensation on the skin surface and thus the shaving sensation.

Abstract: A method for detachment of a mobile set within the equivalent route area moving between the communication systems comprising steps of: during the detachment process is implemented between a mobile set and a service node in one communication system, the service node generates one or more messages and transmits it to the service nodes in one or more communication system within the ERA. If the message is transmitted to the service node within the ERA of only one communication system, this service node transmits this message or the message generated according to this message to the service nodes within the ERA of the other communication system. With the method proposed in present invention, when a mobile is detached from two or more communication systems which share the same ERA, the service nodes in all communication systems within the ERA can still correctly manage the relevant information on this mobile set.

Abstract: Provided is a method for purifying 1,5-pentanediamine comprising: providing 1,5-pentanediamine to be purified and treating the 1,5-pentanediamine to be purified by a reduction reaction to obtain purified 1,5-pentanediamine. Meanwhile, further provided is 1,5-pentanediamine prepared by the method. The purification method has a concise process and a simple operation, and is suitable for industrial production, and can significantly improve the quality of 1,5-pentanediamine.

Abstract: Provided are a lysine decarboxylase immobilized cell and preparation method thereof.

Abstract: This disclosure relates to the field of video coding and decoding technology, and particularly, to a method and an apparatus for coding and decoding videos, wherein the coding method comprises: acquiring available neighboring pixel points which are reconstructed and neighboring to a coding unit; finding a reference block corresponding to the coding unit according to the motion vector of a prediction unit for a pixel attribute in the coding unit, and acquiring corresponding reference pixel points around the reference block; calculating a pixel attribute compensation parameter of the prediction unit using a value of the pixel attribute of the neighboring pixel point and a value of the same pixel attribute of the reference pixel point; and calculating a first prediction value of the prediction unit according to the pixel attribute compensation parameter, and coding the coding unit according to the first prediction value.

Abstract: The present invention provides a method for preparing nylon salt, which comprises mixing 1,5-pentanediamine, water and dicarboxylic acid at a temperature of 65 to 120° C. to obtain a nylon salt, wherein the amount of the water is 2% to 12% by weight based on the total weight of the 1,5-pentanediamine and the dicarboxylic acid. The present invention also provides a nylon salt. According to the present method for preparing nylon salt, the incomplete reaction between the 1,5-pentanediamine and the dicarboxylic acid, which is caused by the nylon salt present during the preparation in a solid state, can be avoided; the reaction between the 1,5-pentanediamine and the dicarboxylic acid can be significantly speeded up, and the reaction time is accordingly shorten. Consequently, the content of diamine and dicarboxylic acid remained in the resulting nylon salt is very low. In addition, the final nylon salt product, which present in a solid state, makes it easier to be stored and transported.

Abstract: This invention involves a fabrication method of fast recovery diode, which includes following steps: growing a sacrificial oxide layer on a surface of an N? substrate; forming a P type doped field-limiting ring region on the substrate; forming a P type doped anode region on the substrate; removing the sacrificial oxide layer; annealing the substrate to form a PN junction; implanting oxygen into the surface of the substrate by ion implantation; annealing the substrate to form a silicon dioxide layer on the surface of the substrate; removing the silicon dioxide layer; forming an anode electrode and a cathode electrode of the fast recovery diode. The method eliminates the curved parts near the silicon surface of the profile of PN junction, decreases electric field intensity at the surface of the substrate, therefore increases the breakdown voltage and reliability of the fast recovery diode.

Abstract: A method for handover of User Entity (UE) by a source Base Station (BS) is provided. The method includes determining whether to handover the UE using an X2 interface, transmitting a handover request message to a target BS, the handover request message including Closed Subscriber Group (CSG) information of the target BS, and receiving a handover request acknowledgement message from the target BS, wherein the determining of whether to handover the UE using the X2 interface includes, if there is the X2 interface between the source BS and the target BS, and if the target BS does not support a CSG or the target BS supports a same CSG supported by the source BS, determining to perform the handover of the UE using the X2 interface, and obtaining the CSG information of the target BS through an X2 interface set up procedure.

Abstract: A medical knife includes a blade plate and a blade portion formed at the distal end of the blade plate. Cutting edges extend from the distal end to the proximal end of the blade portion. Two blade surfaces in the width direction of a back-face portion of the blade portion are formed to gradually increase a distance between opposite side and cutting edge from one of the distal end and the proximal end to the other. The two blade surfaces in the width direction of a front-face portion of the blade portion are formed such that the distance between the opposite side and the cutting edge becomes equal in a zone corresponding to a distal end of the cutting edge and a zone corresponding to a proximal end of the cutting edge, over the entire cutting edge from the distal end to the proximal end of the cutting edge.

Abstract: A median filter device is provided with a reordered circuit, a comparison circuit and a data refresh circuit on the basis of the conventional data buffer circuit and data register circuit. The reorder circuit re-sorts the signal data stored in the data buffer circuit in a preceding clock cycle according to their numerical values. The comparison circuit compares the new signal datum entered in the current clock cycle with the signal data already stored to generate a median. The data refresh circuit updates the signal codes stored in the data register circuit with the signal codes corresponding to the new signal data, for calculation of the median in a following clock cycle. The length of the data buffer circuit and data register circuit can be reduced from N signal data to N-1 signal data, which achieves less data storage capacity, smaller circuit area, easier data processing and higher operation efficiency.

Abstract: A top portion extends from an upper end of a handle. The top portion is curved from the front to the back. A clearance is located between the back side of the razor head and the front of the top portion of the holder. The clearance between the back side of the razor head and the front of the top portion is changed by means of a pivoting mechanism such that, when the razor head is at the neutral position, the clearance at a position separated from the cutting edge is greater than the clearance at a position in the vicinity of the cutting edge. When the razor head is moved from the neutral position to a specified movement position, the clearance at the position separated from the cutting edge is less than the clearance at a position in the vicinity of the cutting edge.

Abstract: A method for handover of User Entity (UE) by a source Base Station (BS) is provided. The method includes determining whether to handover the UE using an X2 interface, transmitting a handover request message to a target BS, the handover request message including Closed Subscriber Group (CSG) information of the target BS, and receiving a handover request acknowledgement message from the target BS, wherein the determining of whether to handover the UE using the X2 interface includes, if there is the X2 interface between the source BS and the target BS, and if the target BS does not support a CSG or the target BS supports a same CSG supported by the source BS, determining to perform the handover of the UE using the X2 interface, and obtaining the CSG information of the target BS through an X2 interface set up procedure.

Abstract: The present disclosure provides mutant vaccinia virus strains that can selectively replicate in tumor cells. The present disclosure also provides use of the mutant vaccinia virus strains for preventing and treating tumors.

Abstract: Cosmos Bipinnatus cotyledons are isolated as explants, and the isolated explants are cultured onto a regeneration medium to obtain regenerated Cosmos Bipinnatus shoots. The regeneration medium optionally includes a basal medium, a cytokinin, an ethylene action inhibitor, and a nitrogen source.

Abstract: A triiodide resin (TR) tube of the present invention has a cylindrical shape. A resin exhaust preventing part is provided at a lower portion of the TR tube, and a triiodide resin is received inside the TR tube. A contaminated culture passes through the TR tube to allow an axenic culture to flow out. When a microalgae culture contaminated with bacteria passes through the TR tube filled with the triiodide resin, a pure culture of microalgae can be prepared by using the sterilizing rate of bacteria populations, which is relatively higher than that of microalgae, due to characteristics of iodine exhibiting negative polarity.

Abstract: Provided is a suction cup device with which the work of attaching the suction cup to the attachment surface, and the work of releasing the attachment can be performed quickly, and with which a fixture member comprised by a fixture that is equipped with a suction cup device can be arranged on the top face of the suction cup device. The suction cup device comprises an operation member capable of reciprocating movement in a direction that intersects with a suction cup support shaft, and a means for applying pulling force to the suction cup support shaft as a result of the movement of the operation member in a predetermined direction. Preferably, the suction cup device comprises an operation member capable of reciprocating sliding movement in a direction that intersects with a suction cup support shaft, and a means for applying pulling force to the suction cup support shaft as a result of the sliding movement of the operation member in a predetermined direction.