Patents Assigned to Ramot - Tel-Aviv University
  • Publication number: 20150189881
    Abstract: The present invention relates to the use of Ornidazole and related compounds as herbicides active on a wide range of photoautotrophic organisms. The compounds of the present invention show effective herbicidal activity while being non-hazardous to the environment and to human health.
    Type: Application
    Filed: July 3, 2013
    Publication date: July 9, 2015
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Yehouda Marcus, Michael Gurevitz
  • Publication number: 20150185218
    Abstract: A method of determining tyrosinase activity of a cell is disclosed. The method comprises: (a) contacting the cell with a phenol under conditions wherein tyrosinase of the cell catalyzes a reaction with said phenol, so as to generate a product which produces an electrical signal; and (b) measuring a level of the electrical signal, thereby determining tyrosinase activity of the cell. Use of the method for detecting melanoma in skin samples is also disclosed.
    Type: Application
    Filed: May 30, 2013
    Publication date: July 2, 2015
    Applicant: Ramot At Tel-Aviv University Ltd.
    Inventors: Sefi Vernick, Yosi Shacham-Diamand, Judith Rishpon, Michal Mossberg, Ofri Vaisman
  • Patent number: 9070453
    Abstract: To store, successively, in a plurality of memory cells, first and second pluralities of input bits that are equal in number, a first transformation transforms the first input bits into a first plurality of transformed bits. A first portion of the cells is programmed to store the first transformed bits according to a mapping of bit sequences to cell levels, but, if the first transformation has a variable output length, only if there are few enough first transformed bits to fit in the first cell portion. Then, without erasing a second cell portion that includes the first portion, if respective levels of the cells of the second portion, that represent a second plurality of transformed bits obtained by a second transformation of the second input bits, according to the mapping, are accessible from the current cell levels, the second portion is so programmed to store the second transformed bits.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: June 30, 2015
    Assignee: Ramot at Tel Aviv University Ltd.
    Inventors: Eran Sharon, Idan Alrod, Simon Litsyn, Ishai Ilani
  • Patent number: 9061006
    Abstract: A method of diagnosing Phenylketonuria (PKU) in a subject in need thereof is disclosed. The method comprises detecting phenylalanine fibrils in a tissue of the subject, wherein a presence or level above a predetermined threshold of said phenylalanine fibrils in said tissue, is indicative of PKU in the subject. Antibodies capable of detecting phenylalanine fibrils are also disclosed as well as additional uses.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: June 23, 2015
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Lihi Adler-Abramovich, Ohad Carny, Ehud Gazit
  • Publication number: 20150164989
    Abstract: A method of treating or preventing an ovary-related syndrome associated with infertility in a subject in need thereof is provided. The method comprising administering to the subject a pharmaceutical composition comprising an active ingredient consisting of pigment epithelium-derived factor (PEDF) and a pharmaceutically acceptable carrier, thereby treating or preventing the ovary-related syndrome associated with infertility in the subject.
    Type: Application
    Filed: February 23, 2015
    Publication date: June 18, 2015
    Applicants: Ramot at Tel-Aviv University Ltd., The Fund for Medical Research, Development of Infrastructure and Health Services - Assaf HaRofeh
    Inventors: Ruth SHALGI, Dana Chuderland, Ido Ben-Ami, Raphael Ronel
  • Publication number: 20150166667
    Abstract: The present invention generally concerns methods and compositions for treating skin hyperplasia and cancer.
    Type: Application
    Filed: October 23, 2014
    Publication date: June 18, 2015
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventor: Efrat WERTHEIMER
  • Patent number: 9057088
    Abstract: Silver-coated proteins, being dissolvable or suspendable in aqueous media and/or retaining a biological activity of the protein and a process for preparing same are disclosed. Further disclosed are modified proteins which have a reducing moiety attached to the surface thereof and a process for preparing same. The modified proteins can be utilized for obtaining the silver-coated proteins. Further disclosed are a pharmaceutical composition containing and a method of treating bacterial and fungal infections utilizing biologically active silver-coated hydrogen peroxide producing enzymes such as glucose oxidase. Further disclosed are conductive elements that comprise the silver-coated proteins disclosed herein and electronic circuits containing same. Further disclosed are electrodes having the silver-coated proteins deposited thereon and biosensor systems utilizing same for determining a level of an analyte in a liquid sample.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: June 16, 2015
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Amihay Freeman, Yosi Shacham-Diamand, Hila Moscovich-Dagan, Noa Hadar
  • Patent number: 9058736
    Abstract: Apparatus for detection of human falls comprises: an acceleration detector, for detecting vibration events, typically placed on a floor, a microphone, located in association with the acceleration detector for detection of corresponding sound events, and a classification unit to classify concurrent events from the microphone and the acceleration detector, thereby to determine whether a human fall is indicated. If the event appears to be a human fall, then an alarm is raised.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: June 16, 2015
    Assignees: Ramot at Tel-Aviv University Ltd., Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Israel Gannot, Dimitry Litvak, Yaniv Zigel
  • Patent number: 9045568
    Abstract: Vinyl terminated polyolefins with long chain branching produced with Salan catalysts having carbazole moieties.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: June 2, 2015
    Assignees: ExxonMobil Chemical Patents Inc., Ramot at Tel-Aviv University Ltd.
    Inventors: Garth R. Giesbrecht, Matthew W. Holtcamp, Moshe Kol
  • Patent number: 9036058
    Abstract: A method of processing a polychromatic image is disclosed. The method comprises, for each of at least a portion of the picture elements, assigning to the picture element a new color value for each individual color, and storing the new values in a computer readable medium. The new values are assigned by: processing each of a first and a second colors of the picture element, based, at least in part on first and second colors of peripheral picture elements, to respectively provide a first processed color value and a second processed color value; employing optimization for reducing error and for assigning to the picture element a new color value for each of the first and second colors; and assigning to the picture element a new color value for a third color calculated based, at least in part, on the new color values for the first and second colors.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: May 19, 2015
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Hedva Spitzer, Yuval Barkan
  • Patent number: 9031417
    Abstract: A modulator device for converting digital data into modulation of an optical signal includes an electronic input for receiving an input data word of N bits and an electrically controllable modulator for modulating the intensity of an optical signal, the modulator including M actuating electrodes where M?N. An electrode actuating device, most preferably a digital-to-digital converter, operates actuating electrodes so that at least one electrode is actuated as a function of values of more than one bit of the input data word. According to an alternative, or supplementary, aspect of the invention, the set of electrodes includes at least one electrode having an effective area which is not interrelated to others of the set by factors of two. In one preferred implementation, a Mach-Zehnder modulator also provides phase modulation to give QAM functionality. Another implementation employs a semiconductor laser.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: May 12, 2015
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Yossef Ehrlichman, Ofer Amrani, Shlomo Ruschin
  • Patent number: 9023800
    Abstract: Isolated DJ-1 related peptides are disclosed and pharmaceutical compositions comprising same for treating oxidative stress-related disorder.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: May 5, 2015
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Daniel Offen, Nirit Lev, Eldad Melamed
  • Patent number: 9023609
    Abstract: The present invention reveals a strong correlation between FGL-2 prothrombinase activity levels and the presence of a malignant proliferative disorder in a subject. Thus, the present invention provides FGL-2 prothrombinase activity as a diagnostic tool for malignancy.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: May 5, 2015
    Assignees: Mor Research Applications Ltd., Ramot at Tel-Aviv University Ltd.
    Inventors: Aida Inbal, Esther Rabizadeh
  • Patent number: 9018257
    Abstract: The present invention provides drug conjugates comprising 5-aminolevulinic acid (ALA), an aldehyde and a carboxylic acid that may function as a histone deacetylase inhibitor (HDACI). These conjugates may serve as co-drugs which release a plurality of active species in vivo. The novel drug conjugates may be used, for the treatment or prevention of cancer in PDT-dependent and/or PDT-independent (nonPDT) treatments, as well as for cosmetic uses. In addition the present invention provides novel uses for both the novel and known compounds. According to some embodiments, the present invention provides drug conjugates (co-drugs) comprising (i) ALA, (ii) an aldehyde and (iii) a carboxylic acid that may function as a histone deacetylase inhibitor (HDACO for the treatment of anemia and/or for the induction of erythropoiesis.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: April 28, 2015
    Assignees: Bar Ilan University, Ramot at Tel Aviv University Ltd.
    Inventors: Ada Rephaeli, Nataly Tarasenko, Zvi Malik, Abraham Nudelman, Gili Berkovitch-Luria, Dvir Doron
  • Patent number: 9018616
    Abstract: A rectifying antenna device is disclosed. The device comprises a pair of electrode structures, and at least one nanostructure diode contacting at least a first electrode structure of the pair and being at least in proximity to a second electrode structure of the pair. At least one electrode structure of the pair receives AC radiation, and the nanostructure diode(s) at least partially rectifies a current generated by the AC radiation.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: April 28, 2015
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Yael Hanein, Amir Boag, Jacob Scheuer, Inbal Friedler
  • Patent number: 9012104
    Abstract: A bipolar plate and regenerative fuel cell stacks including the bipolar plates and membrane electrode assemblies (MEAs) alternately stacked. The bipolar plate comprises a plate main body formed of an electrically conductive material. The plate main body has a first surface and a second surface opposite the first surface. Each surface has reaction flow channels through which fluids pass. The reaction flow channels on the first surface have a plurality of ribs therebetween forming an interdigitate flow field pattern. The reaction flow channels on the second surface have a plurality of ribs therebetween forming an interdigitate flow field pattern or a flow field pattern different from an interdigitate flow field pattern, e.g., a serpentine flow field pattern.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: April 21, 2015
    Assignee: Ramot At Tel-Aviv University Ltd.
    Inventors: Emanuel Peled, Arnon Blum, Adi Aharon, Yaron Konra, Vladimir Zel, Kobby Saadi
  • Patent number: 9013707
    Abstract: A device for optical sensing of substances or environmental conditions in a fluid includes a number of non-overlapping adjacent sensing elements, each having a layered optical element for generating a wavelength-specific interference effect and being treated so as to respond to the presence of a predefined substance or a predefined environmental condition to cause an optically detectable change. The sensing elements are distinct from each other both in their wavelength-specific interference effect and in the corresponding optically detectable change. As a result, when the device is illuminated by a common illumination beam of multi-wavelength illumination, spectral analysis performed on the reflected or transmitted illumination enables simultaneous sensing of a plurality of substances or environmental conditions. In certain preferred implementations, the layered optical element includes at least one layer of porous silicon.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: April 21, 2015
    Assignee: Ramot At Tel-Aviv University Ltd.
    Inventors: Shlomo Ruschin, Tanya Hutter
  • Patent number: 9013691
    Abstract: Snapshot spectral imagers comprise an imaging lens, a dispersed image sensor and a restricted isometry property (RIP) diffuser inserted in the optical path between the source image and the image sensor. The imagers are used to obtain a plurality of spectral images of the source object in different spectral bands in a single shot. In some embodiments, the RIP diffuser is one dimensional. An optional disperser may be added in the optical path, to provide further dispersion at the image sensor. In some embodiments, all imager components except the RIP diffuser may be part of a digital camera, with the RIP diffuser added externally. In some embodiments, the RIP diffuser may be included internally in a digital camera.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: April 21, 2015
    Assignee: Ramot at Tel-Aviv University
    Inventors: Michael Golub, Menachem Nathan, Amir Averbuch, Asaf Kagan, Valery Zheludev, Roman Malinsky
  • Patent number: 8990658
    Abstract: Data that are stored in cells of a multi-bit-per cell memory, according to a systematic or non-systematic ECC, are read and corrected (systematic ECC) or recovered (non-systematic ECC) in accordance with estimated probabilities that one or more of the read bits are erroneous. In one method of the present invention, the estimates are a priori. In another method of the present invention, the estimates are based only on aspects of the read bits that include significances or bit pages of the read bits. In a third method of the present invention, the estimates are based only on values of the read bits. Not all the estimates are equal.
    Type: Grant
    Filed: March 11, 2009
    Date of Patent: March 24, 2015
    Assignee: Ramot at Tel Aviv University Ltd.
    Inventors: Simon Litsyn, Idan Alrod, Eran Sharon, Mark Murin, Menahem Lasser
  • Publication number: 20150075250
    Abstract: A force sensor device has at least three arcs distributed around a central axis. The arcs have integrated sensing elements that measure strain applied on the arc resulting from a force applied on the central axis.
    Type: Application
    Filed: April 29, 2013
    Publication date: March 19, 2015
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Gabor Kosa, Gabor Skekely, Peter Sandor Baki