Patents Assigned to Ratiopharm GmbH
  • SOLID COMPOSITION CONTAINING THE INGREDIENT RASAGILINE
    Publication number: 20130345310
    Abstract: The present invention relates to a solid composition containing at least one pharmaceutically compatible auxiliary ingredient and rasagiline or a pharmaceutically compatible salt thereof as an active ingredient. The invention further relates to a method for producing said solid composition and to a medicine comprising said solid composition.
    Type: Application
    Filed: August 14, 2013
    Publication date: December 26, 2013
    Applicant: RATIOPHARM GMBH
    Inventors: Katrin Rimkus, Sandra Brueck, Frank Muskulus, Jana Paetz
  • Pharmaceutical composition comprising N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5[[[2-(methylsulfonyl)ethyl]amino]methyl]-quinazolinamine
    Patent number: 8586091
    Abstract: The present invention relates to a pharmaceutical composition comprising N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furyl]-4-quinazolinamine as active pharmaceutical ingredient and a process of preparing such composition.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: November 19, 2013
    Assignee: ratiopharm GmbH
    Inventors: Katrin Rimkus, Frank Muskulus, Sandra Brueck, Jana Paetz
  • TRANSDERMAL THERAPEUTIC SYSTEM (TTS) COMPRISING ROTIGOTINE
    Publication number: 20130281944
    Abstract: The present invention relates to a patch containing the active ingredient rotigotine for the transdermal delivery of the active pharmaceutical agent rotigotine, comprising a backing layer (1), a matrix layer (2) containing the active ingredient, and a removable protective sheet (4) which is intended for removal before the patch is applied to the skin, characterized in that disposed with areal coverage between the matrix layer (2) and the removable protective sheet (4) is an additional interlayer (3).
    Type: Application
    Filed: November 29, 2011
    Publication date: October 24, 2013
    Applicant: Ratiopharm GMBH
    Inventors: Christian Drescher, Christian Janssen, Ulrich Becker, Armin Breitenbach
  • DRY PROCESSING OF ATAZANAVIR
    Publication number: 20130224294
    Abstract: The invention relates to dry processes for producing oral dosage forms, more specifically tablets, comprising atazanavir and adhesion enhancers. The invention further relates to compacted intermediates comprising atazanavir and adhesion enhancers.
    Type: Application
    Filed: September 27, 2011
    Publication date: August 29, 2013
    Applicant: RATIOPHARM GMBH
    Inventors: Dominique Meergans, Ralph Stefan
  • SOLID IVABRADINE-CONTAINING COMPOSITION
    Publication number: 20130158008
    Abstract: The present invention relates to a solid composition containing ivabradine or a pharmaceutically acceptable salt thereof. Further, the invention relates to a method for the preparation of such a composition as well as a pharmaceutical product comprising such a composition.
    Type: Application
    Filed: June 14, 2011
    Publication date: June 20, 2013
    Applicant: ratiopharm GmbH
    Inventors: Dominique Meergans, Daniela Stumm, Jens Geier
  • DABIGATRAN ETEXILATE-CONTAINING PHARMACEUTICAL COMPOSITION
    Publication number: 20130149346
    Abstract: The present invention relates to a pharmaceutical composition containing dabigatran etexilate or a pharmaceutically acceptable salt thereof as active ingredient.
    Type: Application
    Filed: March 3, 2011
    Publication date: June 13, 2013
    Applicant: ratiopharm GmbH Graf-Arco-Strasse 3
    Inventors: Dominique Meergans, Jana Paetz
  • ORAL DOSAGE FORM OF DEFERASIROX
    Publication number: 20130142871
    Abstract: The invention relates to an oral dosage form containing deferasirox, binder, disintegrant and optionally wicking agent, wherein the introduction of the dosage form into water leads to a suspension wherein the suspended particles have an average particle size (D50) of 20 ?m to 120 ?m, and also to a method of producing it.
    Type: Application
    Filed: July 7, 2011
    Publication date: June 6, 2013
    Applicant: Ratiopharm GmbH
    Inventors: Jana Paetz, Katrin Rimkus
  • SOLID TAPENTADOL IN NON-CRYSTALLINE FORM
    Publication number: 20130116333
    Abstract: The invention relates to solid tapentadol in non-crystalline form together with a surface stabiliser in the form of a stable intermediate. In the intermediate of the invention, tapentadol is preferably present in amorphous form or in the form of a solid solution. The invention further relates to methods of producing tapentadol in a solid, non-crystalline form and to pharmaceutical formulations containing solid, non-crystalline tapentadol.
    Type: Application
    Filed: May 5, 2011
    Publication date: May 9, 2013
    Applicant: RATIOPHARM GMBH
    Inventors: Jana Paetz, Daniela Stumm, Wolfgang Albrecht, Alexandre Mathieu
  • FINGOLIMOD IN THE FORM OF A SOLID SOLUTION
    Publication number: 20130102682
    Abstract: The invention relates to an intermediate containing fingolimod and matrix material, wherein the fingolimod is present in the matrix material in the form of a solid solution. The invention also relates to granules and pharmaceutical formulations containing fingolimod in the form of a solid solution in matrix material. The subject matter of the invention further relates to methods of preparing a solid solution of fingolimod or of an intermediate, and also granules and pharmaceutical formulations containing fingolimod in the form of a solid solution.
    Type: Application
    Filed: April 21, 2011
    Publication date: April 25, 2013
    Applicant: Ratiopharm GMBH
    Inventors: Jana Paetz, Dominique Meergans
  • MELT-GRANULATED FINGOLIMOD
    Publication number: 20130102683
    Abstract: The invention relates to methods including the step of joint melt processing of (i) fingolimod or a pharmaceutically acceptable salt thereof, with (ii) a matrix former into an intermediate, intermediates obtainable in this way, and oral dosage forms, especially tablets, containing the intermediates of the invention. The invention further relates to a method of preparing the dosage forms of the invention, especially tablets. Finally, the invention relates to oral dosage forms for the treatment of multiple sclerosis.
    Type: Application
    Filed: April 21, 2011
    Publication date: April 25, 2013
    Applicant: RATIOPHARM GMBH
    Inventors: Jana Paetz, Sandra Brueck
  • METHOD OF PREPARING AN ORAL DOSAGE FORM COMPRISING FINGOLIMOD
    Publication number: 20130095177
    Abstract: The present invention relates to a method of preparing an intermediate containing fingolimod, a method of preparing granules containing fingolimod, a method of preparing an oral dosage form containing fingolimod and accordingly intermediates, granules and oral dosage forms obtainable by that method.
    Type: Application
    Filed: April 21, 2011
    Publication date: April 18, 2013
    Applicant: RATIOPHARM GMBH
    Inventors: Jana Paetz, Katrin Rimkus
  • IVABRADINE-CONTAINING PHARMACEUTICAL COMPOSITION
    Publication number: 20130084335
    Abstract: The present invention relates to a pharmaceutical composition containing ivabradine or a pharmaceutically acceptable salt thereof. The invention further relates to a method for the preparation of such a composition.
    Type: Application
    Filed: June 14, 2011
    Publication date: April 4, 2013
    Applicant: ratiopharm GmbH
    Inventors: Dominique Meergans, Katrin Rimkus, Jens Geier
  • RAPID RELEASE IRBESARTAN-CONTAINING PHARMACEUTICAL COMPOSITION
    Publication number: 20130059897
    Abstract: The present invention relates to an irbesartan-containing pharmaceutical composition, in particular a tablet thereof, which comprises the active ingredient, a disintegrant with at least one low-substituted hydroxypropyl cellulose.
    Type: Application
    Filed: October 8, 2012
    Publication date: March 7, 2013
    Applicant: ratiopharm GmbH
    Inventor: ratiopharm GmbH
  • PRASUGREL IN MICRONIZED, CRYSTALLINE FORM AND PHARMACEUTICAL COMPOSITION THEREOF
    Publication number: 20130035355
    Abstract: The present invention relates to Prasugrel or a pharmaceutically acceptable salt thereof, compositions containing said active ingredient as well as pharmaceutical compositions containing said active ingredient or a composition containing said active ingredient. The present invention further relates to methods for the preparation of the novel compositions.
    Type: Application
    Filed: February 10, 2011
    Publication date: February 7, 2013
    Applicant: ratiopharm GmbH
    Inventors: Sandra Brueck, Jana Paetz
  • SOLID PHARMACEUTICAL DOSAGE FORM
    Publication number: 20130028938
    Abstract: The present invention relates to a solid pharmaceutical dosage form comprising ticagrelor as pharmaceutically active ingredient, to certain particles of ticagrelor and to processes of preparing the same.
    Type: Application
    Filed: December 20, 2010
    Publication date: January 31, 2013
    Applicant: ratiopharm GmbH
    Inventors: Sandra Brueck, Dominique Meergans
  • ORODISPERSIBLE TABLET CONTAINING COMPACTED SILDENAFIL BASE
    Publication number: 20120295916
    Abstract: The invention relates to a process for the preparation of a pharmaceutical intermediate, comprising the steps of (i) mixing (a-i) sildenafil base, (b-i) wicking agent, (c-i) disintegrant, (d-i) optionally glidant; (ii) compacting the mixture; and (iii) milling the compacted material; and to an intermediate obtainable by that process. In addition, the invention relates to a process for the preparation of an orally dispersible tablet (hereinafter also referred to as an “orodispersible tablet”) comprising the intermediate of the invention, and to orodispersible tablets obtainable by that process.
    Type: Application
    Filed: December 22, 2010
    Publication date: November 22, 2012
    Applicant: ratiopharm GmbH
    Inventors: Sven Winter, Max-Werner Scheiwe, Dieter Swatschek
  • ESCITALOPRAM AND SOLID PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
    Publication number: 20120288712
    Abstract: The present invention relates to Escitalopram having a small median particle size and a solid pharmaceutical composition comprising the same.
    Type: Application
    Filed: June 22, 2012
    Publication date: November 15, 2012
    Applicant: ratiopharm GmbH
    Inventors: Parshwakumar V. KALYANKAR, Ganesh V. Gat, Jawed Hussain
  • Rapid release irbesartan-containing pharmaceutical composition
    Patent number: 8309607
    Abstract: The present invention relates to an irbesartan-containing pharmaceutical composition, in particular a tablet thereof, which comprises the active ingredient, a disintegrant with at least one low-substituted hydroxypropyl cellulose.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: November 13, 2012
    Assignee: ratiopharm GmbH
    Inventors: Julia Schulze Nahrup, Sandra Brueck, Rainer Alles, Peter Kraass
  • MELT-GRANULATED CINACALCET
    Publication number: 20120270949
    Abstract: The invention relates to an intermediate obtainable by the melt-extrusion of (i) cinacalcet or a pharmaceutically acceptable salt thereof with (ii) a matrix former, and oral dosage forms, especially tablets containing the intermediates of the invention. The invention further relates to a method of preparing the tablets of the invention. Finally, the invention relates to the use of a matrix former and a wicking agent for preparing cinacalcet formulations which can preferably be administered independently of mealtimes.
    Type: Application
    Filed: October 19, 2010
    Publication date: October 25, 2012
    Applicant: ratiopharm GmbH
    Inventors: Jana Paetz, Frank Muskulus
  • COMPOSITION COMPRISING FESOTERODINE AND FIBER
    Publication number: 20120258171
    Abstract: The invention relates to a pharmaceutical composition containing (a) fesoterodine and/or fesoterodine metabolites and (b) fibers, wherein the weight ratio of components (a):(b) is in the range from 1:50 to 1:2; and oral dosage forms containing the pharmaceutical composition. The invention further relates to dry methods of preparing those dosage forms.
    Type: Application
    Filed: October 28, 2010
    Publication date: October 11, 2012
    Applicant: ratiopharm GmbH
    Inventors: Daniela Stumm, Katrin Rimkus