Patents Assigned to Rensselaer Polytechnic Institute
  • Publication number: 20250131520
    Abstract: Systems and methods of predicting the retention rates of students attending an educational institution are provided. The method includes receiving an initial dataset related to a cohort of students attending the educational institution, dividing the initial dataset into a training dataset and a testing dataset, training a predictive algorithm via the training dataset to generate a prediction model, and processing the testing dataset via the prediction model to output a prediction results dataset. The prediction results dataset includes a listing of the cohort of students organized from most likely to leave the educational institution to least likely to leave the educational institution. The method includes filtering a percentage of the prediction results dataset to identify a watchlist of students likely to leave the educational institution.
    Type: Application
    Filed: February 3, 2023
    Publication date: April 24, 2025
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Jasmine Yang, Lu Enzhe, Jiarun Li, Keith Moo-Young, Yihui Yang, Hui Su, Yifan LIU
  • Patent number: 12282694
    Abstract: One embodiment provides a computing device. The computing device is configured to couple to a display. The computing device includes an ambient detection module configured to detect a characteristic of ambient light relative to at least a portion of a display area of the display. The computing device further includes a displayed image optimization module configured to optimize a feature of at least a portion of a displayed image based, at least in part, on the characteristic of the ambient light.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: April 22, 2025
    Assignee: Rensselaer Polytechnic Institute
    Inventor: Michael Shur
  • Publication number: 20250120999
    Abstract: A composition is orally or topically administered to a patient susceptible to infection by an orthopoxvirus such as monkeypox (mpox). The composition includes inhibitors configured to bind to orthopoxvirus envelope proteins, e.g., MPXV A29 from mpox. The inhibitors can include sulfated polysaccharides or glycans such as heparin, chondroitin sulfate A, chondroitin sulfate B (dermatan sulfate), chondroitin sulfate C, chondroitin sulfate D, chondroitin sulfate E, pentosan polysulfate, mucopolysaccharide polysulfate, or combinations thereof. Binding of the composition to the envelope proteins inhibits the interaction between the virions and heparan sulfate proteoglycans (HSPG) and thus the ability of the virions to enter the host cell.
    Type: Application
    Filed: October 4, 2024
    Publication date: April 17, 2025
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Fuming ZHANG, Robert Linhardt, Jonathan Dordick, Deling Shi
  • Patent number: 12267931
    Abstract: A luminaire includes a frame, an ambient light source positioned within the frame adjacent a first end of the frame, a downlight light source positioned within the frame adjacent a second end of the frame, a diffuser connected to the frame and at least partially surrounding the ambient light source, and a reflector configured to direct light emitted by the downlight light source. A first driver is in electrical communication with the ambient light source and is configured to adjust the illuminance of the ambient light source. A second driver is in electrical communication with the downlight light source and is configured to adjust the illuminance of the downlight light source. A controller is in electrical communication with and send control signals to the drivers to change the light sources between a plurality of illuminance modes, which includes a circadian effective mode and a circadian ineffective mode.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: April 1, 2025
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Charles Jarboe, Andrew Bierman, Mariana Gross Figueiro, Mark S. Rea
  • Patent number: 12266104
    Abstract: One embodiment provides an apparatus for fluorescence lifetime imaging (FLI). The apparatus includes a deep neural network (DNN). The DNN includes a first convolutional layer, a plurality of intermediate layers and an output layer. The first convolutional layer is configured to receive FLI input data. Each intermediate layer is configured to receive a respective intermediate input corresponding to an output of a respective prior layer. Each intermediate layer is further configured to provide a respective intermediate output related to the received respective intermediate input. The output layer is configured to provide estimated FLI output data corresponding to the received FLI input data. The DNN is trained using synthetic data.
    Type: Grant
    Filed: January 26, 2024
    Date of Patent: April 1, 2025
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Jason Tyler Smith, Ruoyang Yao, Xavier Intes, Pingkun Yan, Marien Ochoa-Mendoza
  • Patent number: 12265247
    Abstract: In an embodiment, there is provided a light guide for an edge-lit light panel. The light guide includes a first light coupling surface; a second light coupling surface; a first light output surface; and a second light output surface. The second light coupling surface opposes the first light coupling surface. The second light output surface opposes the first light output surface. The first light output surface and the second light output surface are coupled between the first light coupling surface and the second light coupling surface. Each light coupling surface is configured to receive incident light from a respective light source and to produce at least a portion of a batwing light beam inside the light guide. The at least a portion of the batwing light beam is concentrated adjacent the first light output surface, the first light output surface corresponding to a first light extraction surface.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: April 1, 2025
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Xi Mou, Nadarajah Narendran
  • Publication number: 20250102163
    Abstract: One or more temperature control units are distributed throughout an environment to provide localized heating and cooling. The temperature control units include a thermal storage system including one or more substances of high latent heat capacity, a heat distribution surface, a solid-state heat pump positioned between the thermal storage system and the heat distribution surface, an environmental sensing module including a proximity sensor, and unit control modules in communication with the solid-state heat pumps. The solid-state heat pumps are individually controllable so that heating and cooling can be provided simultaneously from separate heat pumps in the same temperature control unit, or separate temperature control units in the same environment.
    Type: Application
    Filed: October 10, 2024
    Publication date: March 27, 2025
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Berardo Matalucci, Theodorian Borca-Tasciuc, Anna Helen Dyson, Benjamin Pearce, Jason Oliver Vollen
  • Patent number: 12258440
    Abstract: Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described.
    Type: Grant
    Filed: October 24, 2023
    Date of Patent: March 25, 2025
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Chulsung Bae, Woo-Hyung Lee
  • Publication number: 20250097611
    Abstract: A cross-connect switch architecture is described. A cross-connect switch device includes a cross-point switch array, a plurality of photo detectors and a plurality of amplifiers. The cross-point switch array includes a plurality of switches. Each switch is coupled between a respective photo detector and a respective amplifier and is configured to couple the respective photo detector to the respective amplifier when the switch is selected.
    Type: Application
    Filed: December 3, 2024
    Publication date: March 20, 2025
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Bassem Fahs, Robert F. Karlicek, JR., Mona Mostafa Hella
  • Publication number: 20250051819
    Abstract: Disclosed herein are novel microbial polycultures of two or more cell strains, capable of producinges, flavonoids, and anthocyanidin-3-O-glucosides, and methods of use thereof. Also disclosed is a microbial cell capable of producing phenylpropanoic acids, and methods of use thereof.
    Type: Application
    Filed: March 27, 2024
    Publication date: February 13, 2025
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Mattheos KOFFAS, John Andrew JONES
  • Patent number: 12220691
    Abstract: An anion exchange membrane is composed of a copolymer of 1,1-diphenylethylene and one or more styrene monomers, such as 4-tert-butylstyrene. The copolymer includes a backbone substituted with a plurality of ionic groups coupled to phenyl groups on the backbone via hydrocarbyl tethers between about 1 and about 7 carbons in length. High-temperature conditions enabled by these copolymers enhance conductivity performance, making them particularly suitable for use in anion exchange membranes in fuel cells, electrolyzers employing hydrogen, ion separations, etc. The properties of the membranes can be tuned via the degree of functionalization of the phenyl groups and selection of the functional groups, such as quaternary ammonium groups. Several processes can be used to incorporate the desired ionic functional groups into the polymers, such as chloromethylation, radical bromination, Friedel-Crafts acylation and alkylation, sulfonation followed by amination, or combinations thereof.
    Type: Grant
    Filed: March 18, 2024
    Date of Patent: February 11, 2025
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Sangwoo Lee, Chulsung Bae, Carrie Lynn Trant
  • Publication number: 20250028128
    Abstract: A system for free-space optical communication includes a first light source configured to emit an information signal, a spatial light modulator configured to shape the information signal, a second light source configured to emit a plurality of beam pulses, at least one spiral phase plate configured to convert each of the plurality of beam pulses into a plurality of vortical beam filaments, and a mirror coupler configured to combine the information signal and the plurality of vortical beam filaments to form a multi-filament beam having the plurality of vortical beam filaments embedded within the information signal. When the multi-filament beam passes through an optically obstructed space the plurality of vortical beam filaments are configured to clear at least one channel in the optically obstructed space for the information signal to pass through.
    Type: Application
    Filed: February 20, 2024
    Publication date: January 23, 2025
    Applicant: Rensselaer Polytechnic Institute
    Inventor: Moussa N'Gom
  • Publication number: 20240424073
    Abstract: A composition includes a contraceptive chimeric virus-like particle with an antigenic carrier domain and one or more antigenic regions from a sperm cell in the antigenic carrier domain, with the antigenic carrier domain including human papillomavirus L1 capsid protein and the antigenic regions including one or more structural elements of the Catsper ion channel complex. When administered to a patient, the contraceptive vaccine stimulates production of anti-sperm antibodies that, upon binding to a sperm cell, inhibit the sperm cell's motility and thus inhibit the ability of the sperm cell to fertilize an egg cell. The induced immunoinfertility of the composition can be reversed for brief or extended lengths of time by overdosing the patient with a reversal agent lacking the antigenic carrier domain but having a protein sequence substantially identical to that of the one or more antigenic regions to sequester the anti-sperm antibodies.
    Type: Application
    Filed: February 9, 2024
    Publication date: December 26, 2024
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Christopher BYSTROFF, Jean-Ju Lucia CHUNG
  • Patent number: 12175734
    Abstract: In some embodiments, a method of machine learning includes identifying, by an auto encoder network, a simulator feature based, at least in part, on a received first simulator data set and an emulator feature based, at least in part, on a received first emulator data set. The method further includes determining, by a synthesis control circuitry, a synthesized feature based, at least in part, on the simulator feature and based, at least in part, on the emulator feature; and generating, by the auto encoder network, an intermediate data set based, at least in part, on a second simulator data set and including the synthesized feature. Some embodiments of the method further include determining, by a generative artificial neural network, a synthesized data set based, at least in part, on the intermediate data set and based, at least in part, on an objective function.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: December 24, 2024
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Daniel David Harrison, Xun Jia, Klaus Mueller
  • Patent number: 12172030
    Abstract: Methods and systems for performing optogenetics using X-rays or ultrasound waves are provided. Visible-light-emitting nanophosphors can be provided to a sample, and X-ray stimulation can be used to stimulate the nanophosphors to emit visible light. Alternatively, ultrasonic waves can be provided to the sample to cause sonoluminescence, also resulting in emission of visible light, and this can be aided by the use of a chemiluminescent agent present in the sample. The emitted light can trigger changes in proteins that modulate membrane potentials in neuronal cells.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: December 24, 2024
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Matthew Getzin, Rachel Berry, Lars Gjesteby
  • Patent number: 12167184
    Abstract: A cross-connect switch architecture is described. A cross-connect switch device includes a cross-point switch array, a plurality of photo detectors and a plurality of amplifiers. The cross-point switch array includes a plurality of switches. Each switch is coupled between a respective photo detector and a respective amplifier and is configured to couple the respective photo detector to the respective amplifier when the switch is selected.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: December 10, 2024
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Bassem Fahs, Robert F. Karlicek, Jr., Mona Mostafa Hella
  • Patent number: 12151002
    Abstract: Imaging systems and methods are provided. Systems and methods of the subject invention can include the use of nanoparticles (for example, nanophosphors) within a sample to be imaged. Excitation with radiation, such X-ray radiation, can be performed on the nanoparticles to give rise to a change in one or more resonance parameters of the nanoparticles, and this change can be measured using magnetic resonance imaging to provide localization information.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: November 26, 2024
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Matthew Webber Getzin, Lars Arne Gjesteby, Wenxiang Cong
  • Patent number: 12152935
    Abstract: A hybrid fiber for detection of UV light is described. The hybrid fiber includes a conductor, a first layer, a photoactive layer, a second layer, and a transparent electrode. The conductor includes a conductive material. The first layer includes a first material deposited onto the conductor. The first material is configured to transport holes and block electrons. The photoactive layer includes a photoactive material coating the first layer. The photoactive material includes a first submaterial and a second submaterial. The second layer includes a second material deposited onto the photoactive layer. The second material is configured to block holes and transport electrons. The transparent electrode includes a transparent electrode material deposited onto the second layer.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: November 26, 2024
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Dali Shao, Shayla Maya Sawyer, Jie Lian
  • Patent number: 12154193
    Abstract: Systems and methods for reconstructing images for computed tomography are provided. Image reconstruction can be based on a realistic polychromatic physical model, and can include use of both an analytical algorithm and a single-variable optimization method. The optimization method can be used to solve the non-linear polychromatic X-ray integral model in the projection domain, resulting in an accurate decomposition for sinograms of two physical basis components.
    Type: Grant
    Filed: July 7, 2022
    Date of Patent: November 26, 2024
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Wenxiang Cong, Qingsong Yang
  • Publication number: 20240376192
    Abstract: Provided herein are conformation-specific antibodies which bind to protein aggregates, such as amyloid fibrils, including aggregates of glucagon and liraglutide. Also provided are methods of using the antibodies to detect protein aggregates in samples, and methods for identifying aggregate-binding antibodies.
    Type: Application
    Filed: November 17, 2023
    Publication date: November 14, 2024
    Applicant: Rensselaer Polytechnic Institute
    Inventor: Peter M. Tessier