Patents Assigned to Rensselaer Polytechnic Institute
  • Patent number: 10657948
    Abstract: A system, method and program product for generating sound masking in an open-plan space. A method is disclosed that includes: establishing a set of acoustic criteria for the space that specifies minimum output levels at a set of specified frequencies; mixing sound samples to create an audio output stream for use as sound masking when broadcast over at least one speaker using a power amplifier; and processing the audio output stream, wherein the processing includes: analyzing the audio output stream with a spectrum analyzer to determine if the minimum output levels at the set of specified frequencies are met; and level adjusting the audio output stream with an equalizer to ensure that minimum output levels at the set of specified frequencies are met but do not exceed a given threshold above the minimum level.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: May 19, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Jonas Braasch, Alana Gloria DeLoach, Jeffrey Parkman Carter
  • Patent number: 10646685
    Abstract: Multipurpose lighting systems and methods of providing controllable lighting are provided. A lighting system includes a sheet of flexible material, a plurality of light sources and a controller. The plurality of light sources are attached to the sheet of flexible material and configured to emit diffused light. The controller is coupled to the plurality of light sources and is configured to control one or more of the plurality of light sources according to one of a plurality of prescribed lighting characteristics associated with a respective plurality of different lighting tasks. In some examples, the lighting system includes a camera coupled to the sheet of flexible material configured to capture at least one image of an object synchronously with the light emitted by the plurality of light sources.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: May 12, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Mark S. Rea, Mariana Gross Figueiro, Martin B. Overington, Jean Paul Freyssinier, Robert White
  • Publication number: 20200139308
    Abstract: The present invention relates to synthetic membranes and use of these synthetic membranes for isolation of volatile organic compounds and purification of water. The synthetic membrane includes a hydrophobic polymer layer located on a polymeric membrane support layer. The invention includes a method of isolating volatile organic compounds with the synthetic membrane by contacting a volatile organic mixture with the hydrophobic polymer layer of the synthetic membrane and removing volatile organic compounds from the polymeric membrane support layer of the synthetic membrane by a process of pervaporation. The invention also includes a method of purifying water with the synthetic membrane by contacting an ionic solution with the hydrophobic polymer layer of the synthetic membrane and removing water from the polymeric membrane support layer of the synthetic membrane by a process of reverse osmosis. The invention also relates to methods of isolating non-polar gases by gas fractionation.
    Type: Application
    Filed: January 3, 2020
    Publication date: May 7, 2020
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Georges BELFORT, Joseph GRIMALDI, Joseph IMBROGNO, James KILDUFF, John Joseph KEATING
  • Patent number: 10643354
    Abstract: Systems and methods for geometric calibration and image reconstruction in computed tomography (CT) scanning using iterative reconstruction algorithms are provided. An iterative reconstruction algorithm can be used to reconstruct an improved image, and then the improved image can be used to adjust inaccurate parameters by using a Locally Linear Embedding (LLE) method. Adjusted parameters can then be used to reconstruct new images, which can then be used to further adjust the parameters. The steps of this iterative process can be repeated until a quality threshold is met.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: May 5, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Mianyi Chen, Yan Xi, Wenxiang Cong
  • Publication number: 20200129540
    Abstract: A heparin structure with increased anticoagulant activity and method of making the same are disclosed. A heparin sample is provided and treated with a heparan sulfate sulfotransferase in an enzymatic reaction to add sulfuryl groups from a sulfuryl group source to the heparin sample, resulting in a heparin structure having above about 8% more 3-O-sulfo groups relative to wild-type bovine intestinal heparin. The added sulfuryl groups modify the heparin structure and increase the sample's binding to antithrombin III and its anticoagulant activity to be more similar and a viable alternative to porcine intestinal heparin. The modified heparin exhibits an anti-FXa activity and an anti-FIIa activity greater than about 180 U/mg, and a ratio of the anti-FXa activity to the anti-FIIa activity of about 0.9 to about 1.1, consistent with U.S. Pharmacopeia (USP) heparin activity specifications.
    Type: Application
    Filed: March 20, 2018
    Publication date: April 30, 2020
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Li Fu, Kevin Li, Daisuke Mori, Makoto Hirakane, Jonathan S. Dordick, Robert J. Linhardt
  • Publication number: 20200111194
    Abstract: A system for generating a high resolution (HR) computed tomography (CT) image from a low resolution (LR) CT image is described. The system includes a first generative adversarial network (GAN) and a second GAN. The first GAN includes a first generative neural network (G) configured to receive a training LR image dataset and to generate a corresponding estimated HR image dataset, and a first discriminative neural network (DY) configured to compare a training HR image dataset and the estimated HR image dataset. The second GAN includes a second generative neural network (F) configured to receive the training HR image dataset and to generate a corresponding estimated LR image dataset, and a second discriminative neural network (DX) configured to compare the training LR image dataset and the estimated LR image dataset.
    Type: Application
    Filed: October 7, 2019
    Publication date: April 9, 2020
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Ge Wang, Chenyu You, Wenxiang Cong, Hongming Shan, Guang Li
  • Publication number: 20200094241
    Abstract: Embodiments of the invention relate generally to anion exchange membranes and, more particularly, to anion exchange membranes comprising a styrene block copolymer and methods for their manufacture. In one embodiment, the invention provides a polymer according to formula IV, wherein x and y are mol %, QA is or each of R1 and R2 is, independently, a linear alkyl chain or a cyclic alkyl chain, and Z is selected from a group consisting of: a linear alkyl chain, a cyclic alkyl chain, and an alkylene ether chain.
    Type: Application
    Filed: November 26, 2019
    Publication date: March 26, 2020
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Chulsung Bae, Angela Dee Mohanty
  • Patent number: 10602265
    Abstract: A coprime microphone array (CMA) system, comprising: a CMA arrangement that includes a pair of uniform linear microphone subarrays that are coincident and have a coprime number of microphones; a computing system that processing signals from each microphone in the CMA arrangement and generates sound localization information.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: March 24, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ning Xiang, Dane Bush
  • Publication number: 20200091535
    Abstract: Hydrocarbon proton exchange membranes are disclosed that are composed of a material including a hydrophobic main chain, and acidic side chains. The main chain includes a polyaryl structure that is substantially free of ether linkages and also includes a fluoromethyl substituted carbon. The acidic side chains include a hydrocarbon tether terminated by a strongly acidic group, such as a fluoroalkyl sulfonate group. Chemical stability of the material is increased by removing the ether linkages from the main chain. The hydrophobic main chain and substantially hydrophilic side chains create a phase-separated morphology that affords enhanced transport of protons and water across the membrane even at low relative humidity levels. These materials are advantageous as membranes for use in fuel cells, redox flow batteries, water hydrolysis systems, sensors, electrochemical hydrogen compressors, actuators, water purifiers, gas separators, etc.
    Type: Application
    Filed: December 20, 2017
    Publication date: March 19, 2020
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Chulsung BAE, Eun Joo PARK, Junyoung HAN
  • Publication number: 20200090781
    Abstract: Method, system and computer program product are provided for estimating a circadian phase of a subject by: obtaining a sensed biological signal for the subject; and using, by one or more processors, adaptive frequency tracking to adaptively estimate the circadian phase of the subject from the sensed biological signal. Circadian phase estimation may be accelerated by providing a feedback loop for the adaptive frequency tracking, which utilizes, in part, a circadian phase model in automatically ascertaining a phase correction for the adaptive frequency tracking. The circadian phase estimation may be used in automatically constructing a light-based circadian rhythm model for the subject using a linear parameter-varying (LPV) formulation, and once constructed, the circadian rhythm model for the subject may be used to provide light-based circadian rhythm regulation.
    Type: Application
    Filed: November 20, 2019
    Publication date: March 19, 2020
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Jiaxiang ZHANG, John T. WEN, Agung JULIUS
  • Patent number: 10583429
    Abstract: The present disclosure is directed to mixed mode chromatography media comprising a ligand directly attached to a solid support. In some aspects, the ligand has a chemical formula of The mixed mode chromatography media is useful for binding and purifying proteins from a solution.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: March 10, 2020
    Assignees: Bio-Rad Laboratories, Inc., Rensselaer Polytechnic Institute
    Inventors: Steven Cramer, James Woo, Hong Chen, Jiali Liao, Russell Frost
  • Publication number: 20200072259
    Abstract: Methods and systems for controlling a fluid flow field near a surface are disclosed. In some embodiments, the system includes an array of oscillating bodies disposed on the surface to provide physical modification to the flow field. Fluid jets are also emitted from an outlet in the oscillating body to provide virtual modification of the flow field through momentum addition. Fluid jet sources, including synthetic jet generators such as piezoelectric drivers and sources of compressed fluids such as air or water, are positioned to be in fluid communication with the outlet at intervals during the oscillation of the oscillating body. Controlling the oscillation amplitude and frequency of the body, as well as the location of oscillating body outlets and frequency of fluid jet emission, have advantageous effects for the surface such as improved heat transfer properties and reduction in structural vibration and noise.
    Type: Application
    Filed: November 6, 2019
    Publication date: March 5, 2020
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Michael Amitay, Samantha Gildersleeve
  • Publication number: 20200055980
    Abstract: Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described.
    Type: Application
    Filed: August 28, 2019
    Publication date: February 20, 2020
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Chulsung BAE, Woo-Hyung LEE
  • Publication number: 20200053913
    Abstract: Methods, systems, and assemblies for cooling an electronic component are disclosed. A heat sink assembly includes first and second substrates. The first substrate is in thermal contact with the electronic component. A primary channel is formed in the second surface of the first substrate. The primary channel is configured to direct cooling fluid for cooling the electronic component. An array of primary cooling fluid fins is positioned within the primary channel. The array of primary cooling fluid fins includes upstream solid fins and downstream open fins each having an upstream opening and downstream sidewalls. The secondary channel is formed within the second surface of the second substrate and is configured to direct partially heated cooling fluid away from the electronic component. An array of secondary cooling fluid fins is positioned within the secondary channel downstream. An enclosing layer seals the secondary channel.
    Type: Application
    Filed: October 10, 2019
    Publication date: February 13, 2020
    Applicant: Rensselaer Polytechnic Institute
    Inventors: Corey Christopher Woodcock, Joel L. Plawsky, Yoav Peles, Xiangfei Yu
  • Patent number: 10548543
    Abstract: Novel and advantageous methods and systems for performing spectral computed tomography are provided. An edge-on detector, such as a silicon strip detector, can be used to receive X-rays after passing through a sample to be imaged. An energy resolving process can be performed on the collected X-ray radiation. The CT scanner can have third-generation or fourth-generation geometry.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: February 4, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Yan Xi, Wenxiang Cong, Zaifeng Shi
  • Patent number: 10539689
    Abstract: Novel and advantageous methods and systems for performing computed tomography (CT) imaging are disclosed. Electrodes can be connected to appropriate surface sites of a detector element of a CT scanner to capture nearby electron-hole pairs generated by X-rays received on the detector element. This detection can be performed in current-integrating/energy-integrating mode.
    Type: Grant
    Filed: January 25, 2016
    Date of Patent: January 21, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Wenxiang Cong, Zaifeng Shi
  • Patent number: 10537299
    Abstract: Systems and methods for determining an attenuation sinogram for a time-of-flight (TOF) positron emission tomography (PET) scan using only TOF PET data, and including use of the total amount of tracer provided to the subject of the TOF PET scan, are provided. The total amount of injected tracer can be used to determine the otherwise unknown constant shift present when an attenuation sinogram is estimated using the gradient of the attenuation sinogram. The attenuation sinogram can therefore be accurately and stably determined without any additional knowledge on the attenuation sinogram or map.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: January 21, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Ge Wang, Qingsong Yang, Wenxiang Cong
  • Patent number: 10532326
    Abstract: The present disclosure relates to, inter alia, a modified surface comprising an optically active monomer, a polymeric material having a surface onto which the optically active monomer is covalently bound. In one aspect, a membrane comprising an optically active monomer, a poly(aryl sulfone) membrane having a surface onto which the optically active monomer is covalently bound. The present disclosure also relates to a method of modifying a surface, the method comprising applying sufficient energy to a surface to induce covalent bonding with an optically active monomer, and contacting the optically active monomer with the surface. In one aspect, a method of modifying a surface of a poly(aryl sulfone) membrane is disclosed. In another aspect, a method of synthesizing an optically active monomer is disclosed. In one aspect, a method of filtration of chiral compounds is disclosed.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: January 14, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Georges Belfort, Joseph Imbrogno
  • Patent number: 10525457
    Abstract: Embodiments of the invention relate generally to anion exchange membranes and, more particularly, to anion exchange membranes comprising a styrene block copolymer and methods for their manufacture. In one embodiment, the invention provides a polymer according to formula IV, wherein x and y are mol %, QA is or each of R1 and R2 is, independently, a linear alkyl chain or a cyclic alkyl chain, and Z is selected from a group consisting of: a linear alkyl chain, a cyclic alkyl chain, and an alkylene ether chain.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: January 7, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Chulsung Bae, Angela Dee Mohanty
  • Patent number: 10526616
    Abstract: An improved nanoparticle for transfecting cells is provided. The nanoparticle includes a core polyplex and a silica coating on the core polyplex and, optionally, a polymer attached to an outer surface of the silica coating, where the polyplex includes an anionic polymer, a cationic polymer, a cationic polypeptide, and a polynucleotide. Also provided is an improved method of modifying intracellular polynucleotides. The method includes contacting a cell with a nanoparticle that includes a core polyplex and a silica coating on the core polyplex and, optionally, a polymer attached to an outer surface of the silica coating, where the polyplex includes an anionic polymer, a cationic polymer, a cationic polypeptide, and a polynucleotide.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: January 7, 2020
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Shiva Prasad Kotha, Andre Ronald Watson, Vaibhav A. Pandit