Patents Assigned to Research Corporation Technologies, Inc.
  • Patent number: 4908356
    Abstract: A compound of the formula ##STR1## wherein R.sup.1 and R.sup.2 may be the same of different and are each independently hydrogen or lower alkyl which may be unsubstituted or monosubstituted with halogen, lower alkoxy or hydroxy with the proviso that the substituent is not the .alpha.-carbon or R.sup.1 and R.sup.2 taken together with the carbon to which they are attached form a morpholino ring;each R.sup.3 is independently hydrogen, lower alkyl, carboxy or carbalkoxy;n is an integer from 0, 1, 2 or 3 andR is hydrogen, lower alkyl, cycloalkyl, arylalkyl aryl or a nitrogen, sulfur or oxygen containing heterocyclic or a heterocyclic lower alkyl and pharmacuetically acceptable salts thereof.
    Type: Grant
    Filed: May 25, 1988
    Date of Patent: March 13, 1990
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Richard F. Borch, Ronald R. Valente
  • Patent number: 4897957
    Abstract: The precision flowering of Regal Pelargoniums includes the following six stages: the production of pathogen indexed Mother Block and selection phase, the stock plant production phase, the vegetative propagation post-harvest phases. By means of temperature control and misting during vegetative propagation, careful control of temperature and accumulated light during floral initiation, and night-break lighting during finishing if necessary, flowering Regal Pelargoniums may be produced any time during the year. Moreover, as a result of the combined method steps of the present application, the production of a finished, flowering plant from a stock plant cutting may be completed in a total of 13 to 16 weeks.
    Type: Grant
    Filed: April 12, 1988
    Date of Patent: February 6, 1990
    Assignees: Oglevee, Ltd., Research Corporation Technologies, Inc.
    Inventors: J. Robert Oglevee, Richard Craig
  • Patent number: 4880622
    Abstract: Novel poly(organophosphazene) polymers are used for the controlled release of pharmaceuticals, pesticides, herbicides, plant growth regulators and fertilizers. These polymers also act as foam control agents.
    Type: Grant
    Filed: May 20, 1986
    Date of Patent: November 14, 1989
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Harry R. Allcock, Paul E. Austin, Sukky Kwon
  • Patent number: 4880779
    Abstract: The present invention relates to a method of prevention or treatment of AIDS by inhibition of the human immunodeficiency virus (HIV). Inhibition of the virus is achieved by administration of an inhibitory peptide containing the sequence Phe-X-Gly, wherein X is an amino acid.
    Type: Grant
    Filed: July 31, 1987
    Date of Patent: November 14, 1989
    Assignee: Research Corporation Technologies, Inc.
    Inventor: William R. Gallaher
  • Patent number: 4876399
    Abstract: The present invention is directed to novel taxols useful as a chemotherapeutic agent. Moreover, the present invention is directed to the process of preparing taxols and various intermediates in said process. A key intermediate is this process is 2,5-dihydroxy-2-patchoulenes. Therefore the present invention is also related to said intermediate and the process for its preparation.
    Type: Grant
    Filed: November 2, 1987
    Date of Patent: October 24, 1989
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Robert A. Holton, Rouh-Rong Juo, Richard Lowenthal
  • Patent number: 4861321
    Abstract: An assembly comprising a pulley sub assembly and a shift sub assembly. The pulley sub assembly includes a plurality of pulleys, each pulley includes a plurality of sections, and at least one section of each pulley is axially moveable. The shift sub assembly has a disengaged position to maintain the pulleys in normal positions, and an engaged position. With one embodiment, when the shift sub-assembly is in the engaged position, it slides a section of a first pulley from the plane thereof, into the plane of a second pulley, and then back into the plane of the first pulley. With an alternate embodiment, when the first sub-assembly is in the engaged position, it slides all of the sections of a pulley, one at a time, into the plane of another pulley.
    Type: Grant
    Filed: June 9, 1988
    Date of Patent: August 29, 1989
    Assignee: Research Corporation Technologies, Inc.
    Inventor: John T. Siegwart, Jr.
  • Patent number: 4861989
    Abstract: This disclosure is concerned with method and apparatus for vaporizing liquid solutions in order to detect, quantitate, and/or determine physical or chemical properties of samples present in liquid solution. Mixtures may be separated by an on-line liquid chromatographic column and the methods used for detection, quantitation, indentification, and/or determination of chemical and physical properties include mass spectrometry, photoionization, flame ionization, electron capture, optical photometry, including UV, visible, and IR regions of the spectrum, light scattering, light emission, atomic absorption, and any other technique suitable for detecting or analyzing molecules or particles in a gaseous or vacuum environment. The method and apparatus involves controlled partial vaporization of the solution.
    Type: Grant
    Filed: March 2, 1988
    Date of Patent: August 29, 1989
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Marvin L. Vestal, Calvin R. Blakley, Gordon J. Fergusson
  • Patent number: 4833230
    Abstract: A new class of polyhydroxypolyamides is disclosed. The polyhydroxypolyamides, useful as fibers, plastics, coatings and adhesives, are characterizied by the repeating structural unit--CO--(CHOH).sub.x --CO--NHCH.sub.2 --(CR.sup.1 H).sub.y --CH.sub.2 NH].sub.nwhere R.sup.1 and R.sup.2 are the same or different and are hydrogen, C.sub.1 -C.sub.50 alkyl, C.sub.2 -C.sub.50 alkenyl or C.sub.7 -C.sub.50 aralkyl; x is an integer of 1 to 6; y and z are the same or different and are 0 or an integer of 1 to about 30; and n is an integer of at least about 10.A process for making these polyhydroxypolyamides is also taught. It includes the steps of reacting an aldaric compound, said compound selected from the group consisting of a diacid, an acid-lactone, a dilactone and mixtures thereof, with an alkanol to form an esterification product and forming the polyhydroxypolyamide by polymerizing the esterification product with a primary amine in a polar solvent.
    Type: Grant
    Filed: June 21, 1988
    Date of Patent: May 23, 1989
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Donald E. Kiely, Tsu-Hsing Lin
  • Patent number: 4820300
    Abstract: A totally implantable artificial heart that utilizes a fluid displaced from the left blood pump to power the right blood pump. The left blood pump is a sac-type pump powered by an electric motor that, when contracting and expanding, displaces a volume of fluid in a fluid chamber within the left pump housing. The fluid is displaced through a fluid line connecting the right blood pump, which is a pneumatically operated sac-type or rotary-type pump. The artificial heart permits spatial separation of the left and right blood pumps within the chest of the patient for ease in implantation.
    Type: Grant
    Filed: June 1, 1987
    Date of Patent: April 11, 1989
    Assignee: Research Corporation Technologies, Inc.
    Inventors: William S. Pierce, Gerson Rosenberg
  • Patent number: 4777363
    Abstract: An atmospheric ion mobility spectrometer including a spectrometer tube having a shutter grid defining a reaction region and a drift chamber. The tube includes an inlet at the end of the drift chamber opposite the shutter grid in communication with ambient air that allows the air to be introduced into the tube. The air acts as the sample, carrier gas and drift gases within the IMS.
    Type: Grant
    Filed: August 29, 1986
    Date of Patent: October 11, 1988
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Gary A. Eiceman, Craig S. Leasure
  • Patent number: 4731238
    Abstract: The invention concerns a novel lymphocyte hybridoma and an antibody which may be generated from the hybridoma. The hybridoma and antibody have the internal designation LICR-LON-Fib 75. The origin, method of preparation and uses are discussed. The antibody has particular application in the diagnosis and treatment of cancer of the breast. A particular therapeutic treatment comprises harvesting a sample of bone marrow from a patient, subjecting the patient to treatment adapted to kill cancerous material including that within the bone marrow (possibly including the normal differentiated haemopoietic cells of the marrow), subjecting some or all of the sample to cytotoxic treatment with the antibody (or a toxin conjugate thereof) adapted to kill cancerous cell lines while leaving viable colony-forming units of bone marrow, and reintroducing the treated sample material to the blood stream of the patient.
    Type: Grant
    Filed: December 5, 1983
    Date of Patent: March 15, 1988
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Alexander M. Neville, Christopher S. Foster, Paul A. W. Edwards, Robert A. J. McIlhinney
  • Patent number: 4713336
    Abstract: This invention relates to the field of lignin degradation. More specifically the invention relates to methods for selecting and isolating microorganism from nature that are capable of degrading lignin, processes for cloning a gene segment from such an organism, and methods of using the enzyme product of the gene segment to provide valuable chemical feedstocks, methanol and the like from a lignin source material.
    Type: Grant
    Filed: September 27, 1984
    Date of Patent: December 15, 1987
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Vadake R. Srinivasan, Jeffrey W. Cary, Younghae Chon, Kenneth E. Narva
  • Patent number: PP6654
    Abstract: This invention relates to a new distinct cultivar of geranium substantially as illustrated and described, characterized as being particularly well adapted to both commercial greenhouse production as well as garden performance, and as being early, floriferous, self-branching, compact, heat-tolerant and low-light-tolerant.
    Type: Grant
    Filed: July 17, 1987
    Date of Patent: March 7, 1989
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Richard Craig, Leon Glicenstein
  • Patent number: PP7343
    Abstract: This invention relates to a new and distinct cultivar of regal pelargonium (Pelargonium.times.domesticum) named `Crystal` substantially as illustrated and described herein, particularly characterized as being compact and self-branching, early flowering and floriferous, exhibiting excellent postharvest keeping quality, and having white flowers with distinctive red feathering on the upper two petals thereof.
    Type: Grant
    Filed: April 10, 1989
    Date of Patent: October 2, 1990
    Assignee: Research Corporation Technologies, Inc.
    Inventors: Richard Craig, Glenn G. Hanniford