Abstract: Provided herein are composite conductors, characterized by having copper deposits inside the bulk rather than on the outer surface of a non-metallic conductive porous matrix, such as CNT fabric, as well as a process for obtaining the same. The composite conductors provided herein are also characterized by a low specific weight and a high ampacity compared to metal conductors of similar size and shape.

Abstract: Computerized systems and methods for digital histopathology analysis are disclosed. In one embodiment, a series of deep learning networks are used that train, in succession, on datasets of successively increasing relevance. In some examples, learned parameters from at least a portion of one deep learning network are transferred to a next deep learning network in a succession of deep learning networks. In some examples, at least one of the deep learning networks includes a self-supervised learning network. In some examples, at least one of the deep learning networks includes an attention-based learning network. These and other examples and details are disclosed herein in various contexts including, for example evaluating genotypes of cancer tissue (e.g., bladder, prostate, or lung cancer) using histopathology images. In some examples, the context is to assist in predicting presence or absence of certain cancer genotypes and/or predicting patient responses to a new treatment.

Abstract: The present invention relates to an heparanase-binding and heparanase-neutralizing monoclonal antibody (IgG-1 mAb A54), including its epitope (HBD-II) and mode of interaction with heparanase, pharmaceutical composition comprising same, and uses thereof e.g. for inhibiting or treating a disease or disorder associated with heparanase activity, including but not limited to cancer, inflammation, viral infection, diabetes and related complications. The present invention further provides combinatorial cancer therapies, comprising the heparanase-neutralizing mAb and an additional anti-cancer treatment such as chemotherapy or radiation.

Abstract: An automobile seat integrated with height adjustment and angle adjustment comprises a seat body comprising a pedestal skeleton and a backrest skeleton, a height adjustment mechanism comprising a bottom support, a rear connection rod, an upper connection rod and a front connection rod and an angle adjustment mechanism comprising the bottom support, an angle adjustment connection rod, a driving connection rod, a front connection rod and the upper connection rod, the bottom support, the front connection rod and the upper connection rod are common parts of the height adjustment mechanism and the angle adjustment mechanism, the bottom support, the rear connection rod, the upper connection rod and the front connection rod are successively adjacently connected by rotating pairs, and the rear connection rod is connected with a height adjustment driving source which drives the rear connection rod to move when working to realize the height adjustment of the automobile seat.

Abstract: The present invention, is directed to a method for selecting an improved genetically modified Solanum plant, the method including: determining the presence of at least one inactive allele of auxin responsive factor (ARF) 8 gene in the genome of the genetically modified Solanum plant or a part derived therefrom; and (b) selecting a genetically modified Solanum plant determined as having a genome including the at least one inactive allele of ARF8 gene, wherein the improvement is at least any one of: (i) increased yield; (ii) increased resistance to a pathogen; (iii) earlier fruit setting; and (iv) any combination of (i) to (iii), compared to a wild-type variant of said Solanum plant, thereby, selecting an improved genetically modified Solanum plant.

Abstract: Novel inhibitors of MetAp2 enzymatic activity and uses thereof are provided.

Abstract: Generally, disclosed herein are various embodiments of bonding agents for use in adhering optical fibers to ferrules within optical connectors, and the methods for use thereof. The various embodiments of bonding agents described herein may provide desirable properties, such as, but not limited to, high adhesion strength and/or improved performance following environmental aging. Various embodiments of the bonding agents disclosed herein may also have other desirable properties for the process of securing an optical fiber within a ferrule, such as, but not limited to, shortened process cycle time.

Abstract: The present disclosure relates to an artificial agglomerated stone comprising micronized feldspar and to a method for its manufacturing.

Abstract: The present disclosure relates to a fiber optic assembly that includes a body and a lid coupled to the body where the body and the lid each define a respective fiber routing plane. The fiber optic assembly also includes a plurality of ports on the body and a plurality of ports on the lid such that when the lid and the body are in a closed configuration, the ports of the body and the ports of the lid define a singular connection plane.

Abstract: A monitoring apparatus for a package includes a pressure applying device configured to apply a pressure to the package, a sensor configured to measure the pressure applied to the package by the pressure applying device, and a signal transmitting apparatus electrically coupled to the package and configured to input an input signal to a chip of the package, receive an output signal from the package in real time, and monitor a damage of the chip of the package in real time while the pressure applying device applies the pressure to the package.

Abstract: A direct gaseous reformate injector that includes an inlet for receiving a gaseous reformate; a plunger; and an outward-opening valve that comprises a valve body and a needle that is movable, by the plunger, in relation to the valve body, between a (a) closed position in which the gaseous reformate is not outputted from the direct gaseous reformate injector, and (b) an open position in which the gaseous reformate is outputted from the direct gaseous reformate injector.

Abstract: Various embodiments provide an optical lens that includes wafer level diffractive microstructures. In one embodiment, the optical lens includes a substrate, a microstructure layer having a first refractive index, and a protective layer having a second refractive index that is different from the first refractive index. The microstructure layer is formed on the substrate and includes a plurality of diffractive microstructures. The protective layer is formed on the diffractive microstructures. The protective layer provides a cleanable surface and encapsulates the diffractive microstructures to prevent damage and contamination to the diffractive microstructures. In another embodiment, the optical lens includes a substrate and an anti-reflective layer. The anti-reflective layer is formed on the substrate and includes a plurality of diffractive microstructures.

Abstract: An optical fiber cable that includes subunits is provided. The cable has an outer jacket having a thickness of at least 2.0 millimeters and that is made from a fire retardant polymer material having a PHRR value of 222 kw/m2 when tested in a cone calorimeter measured according to ASTM E1354 with a heat flux of 50 kW/m2. The cable meets the requirement of UL 1666 burn test for riser cables and the requirements of EN 50399 burn test for CPR class Cca cables.

Abstract: An optical fiber cable is provided. The optical fiber cable includes an outer jacket having an outer surface defining an outermost surface of the optical fiber cable and an inner surface defining a central bore. The optical fiber cable includes a plurality of aramid fibers located in the central bore, and the plurality of aramid fibers have a relatively low total linear density such that a total linear density of all aramid fibers within the central bore is less than 10,000 dtex. The optical fiber cable includes at least one optical fiber located within the central bore, and the at least one optical fiber has a proof test of greater than 100 kpsi.

Abstract: The present invention relates to a method of determining the trapped volume and the trapped aqueous volume of a plurality of liposomes in a liposomal composition. The method can be used for calculating the concentration of an active pharmaceutical ingredient entrapped within the liposomes and for quality assurance of a pre-formed liposomal composition.

Abstract: A method of treating a disease or disorder for which an increase in immune cells in the brain is therapeutic in a subject is disclosed. The method comprises administering to the subject a therapeutically effective amount of an agent which specifically binds and increases activity of a receptor selected from the group consisting of a 5HT2C receptor, a 5HT2A receptor and a 5HT2B receptor in the postcentral gyrus and/or the choroid plexus (CP) of the brain of the subject. Compositions for treating these diseases are also disclosed.

Abstract: The technology subject of the present application concerns a novel class of fused nanocrystal molecules having unique electronic properties. The application further contemplates methods for their preparation and methods of their use.

Abstract: Provided is a polypeptide having phospholipase C activity. The polypeptide has: 1) an amino acid sequence represented by SEQ ID No: 2, comprising amino acid substitutions occurred at one or more positions, wherein the one or more positions are selected from positions 6, 8, 10, 104, and 205 in the amino acid sequence represented by SEQ ID No: 2 or any combination thereof; or 2) having at least 80% sequence identity with 1), and at least one of positions 6, 8, 10, 104 and 205 being different from positions 6, 8, 10, 104, and 205 in the amino acid sequence represented by SEQ ID No: 2. Provided are a nucleic acid molecule for encoding the polypeptide, a vector comprising the nucleic acid molecule, and a cell comprising the nucleic acid molecule or the vector. Provided are uses of the polypeptide, the nucleic acid molecule, the vector, and the cell.

Abstract: A method of preparing a composition comprising mycelium along with a cellulose and/or plurality of nanoparticles is described herein. The method comprises inoculating a liquid medium with fungus, the liquid medium comprising nutrients and the cellulose and/or nanoparticles. Further described herein are compositions comprising mycelium along with a cellulose and/or plurality of nanoparticles, as well as articles-of-manufacture comprising such a composition, wherein at least 10% of the cellulose and/or nanoparticles in the composition is incorporated within the mycelium. A method of enhancing fungal growth is also described, comprising contacting the fungus with a liquid medium comprising a polymer which comprises carboxylic acid groups.

Abstract: A technique to mitigate timing errors induced by power supply droops includes an inverter-based droop detector as well as Dual Mode Logic (DML) to achieve a droop-resist ant timing response. The droop detector is based on capacitor ratios and is thus less sensitive to Process/Voltage/Temperature (PVT) and to random offset than the prior art. The DML can alter its power/performance ratio based on the droop level input it receives from the detector, such that the critical timings are preserved.