Patents Assigned to Research Development
  • System for monitoring and displaying status of processing a dairy product
    Patent number: 12127527
    Abstract: Systems and methods for monitoring a cheesemaking process, and for identifying certain stages of the process, are disclosed. The system includes a sonic sensor, along with a processor that will receive, from the sonic sensor, a signal that is indicative of a speed of sound in a material that is being processed in the cheesemaking process. The processor will use the speed of sound to identify a cut point in the cheesemaking process. The processor will generate a signal when the cut point is reached. Optionally, before this happens the processor also may use the speed of sound to identify a flocculation point in the cheesemaking process.
    Type: Grant
    Filed: May 9, 2022
    Date of Patent: October 29, 2024
    Assignee: TZero Research & Development LLC
    Inventors: Stephen M. Wells, Nicholas A. Wells, Eli M. Hughes
  • BIOMARKERS TO DETECT RISK OF SINUSOIDAL OBSTRUCTION SYNDROME
    Publication number: 20240353424
    Abstract: The present disclosure provides biomarker panels for evaluating subjects at risk of sinusoidal obstruction syndrome (SOS) early after hematopoietic stem cell transplantation (HSCT). In particular, the present disclosure relates to the use of ST2. L-Ficolin, and HA for prognosing, diagnosing, and/or treating SOS.
    Type: Application
    Filed: April 11, 2024
    Publication date: October 24, 2024
    Applicant: MUSC Foundation for Research Development
    Inventor: SOPHIE PACZESNY
  • TOPICAL DELIVERY SYSTEMS FOR ACTIVE COMPOUNDS
    Publication number: 20240350401
    Abstract: The disclosure concerns viscous or gelled delivery systems based on oily nano-domains dispersed in a viscosified/gelled continuous aqueous phase, and suitable for prolonged and/or sustained topical delivery of various active compounds.
    Type: Application
    Filed: June 27, 2024
    Publication date: October 24, 2024
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., LYOTROPIC DELIVERY SYSTEMS LTD
    Inventors: Nissim GARTI, Sharon GARTI LEVI
  • REWARD SYSTEM ACTIVATION FOR THERAPEUTIC PURPOSES
    Publication number: 20240352484
    Abstract: Provided is reward system activation for therapeutic purposes. Accordingly there is provided a method of treating a disease in a subject in need thereof, the method comprising subjecting the subject to a treatment module which activates the reward system of the subject.
    Type: Application
    Filed: April 18, 2024
    Publication date: October 24, 2024
    Applicants: Technion Research & Development Foundation Limited, Rambam Med-Tech Ltd.
    Inventors: Asya ROLLS, Lior GEPSTEIN, Hedva HAYKIN, Hilla AZULAY-DEBBY
  • Patient lift and sling having wireless communication
    Patent number: 12121486
    Abstract: A person lift system includes a motor and a sling bar coupled to the motor. The sling bar includes a first attachment hook at a first end region of the sling bar and a second attachment hook at a second end region of the sling bar. A sling includes a main body section and a plurality of loops coupled to the main body section. Each of the plurality of loops is configured to attach to one of the plurality of attachment hooks. A first electronic reader is coupled to the sling bar near the first attachment hook. A second electronic reader is coupled to the sling bar near the second attachment hook. Each of a plurality of short range wireless tags is coupled to a respective one of the plurality of loops.
    Type: Grant
    Filed: September 7, 2023
    Date of Patent: October 22, 2024
    Assignee: Liko Research & Development AB
    Inventors: Philippe Kaikenger, Clementine Pirio, Jean-Bernard Duvert, Mickael Audic, Marcus Linde, Daniel Johansson, Johanna Sundqvist
  • COMPOUNDS AND USES THEREOF IN THE TREATMENT AND PREVENTION OF DISEASES AND CONDITIONS ASSOCIATE WITH OR AGGRAVATED BY IMPAIRED MITOPHAGY OR OXIDATIVE STRESS
    Publication number: 20240343696
    Abstract: The invention provides compounds and uses thereof in the treatment and prevention of diseases and conditions associate with or aggravated by impaired mitophagy or oxidative stress, and methods of their preparation.
    Type: Application
    Filed: July 5, 2022
    Publication date: October 17, 2024
    Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: Shmuel BEN-SASSON Z”L, Einav GROSS
  • NOMADIC BACTERIA AND USES THEREOF
    Publication number: 20240336889
    Abstract: A method of generating a biofilm of nomadic bacteria. The method comprises: (a) culturing the nomadic bacteria in an acidic environment under conditions that promote generation of a V-type structure of the nomadic bacteria; and subsequently (b) culturing said nomadic bacteria having a V-type structure on an adherent surface, thereby generating the biofilm comprising the nomadic bacteria. Conditioned media of nomadic bacteria are also disclosed and uses thereof.
    Type: Application
    Filed: June 18, 2024
    Publication date: October 10, 2024
    Applicants: The State of Israel, Ministry of Agriculture & Rural Develoment, Agricultural Research Organization, Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Moshe SHEMESH, Satish Kumar RAJASEKHARAN, Doron STEINBERG
  • FORMULATION AND METHOD FOR INCREASING ORAL BIOAVAILABILITY OF DRUGS
    Publication number: 20240335391
    Abstract: The application discloses a formulation and method for increasing bioavailability of an orally administered drug.
    Type: Application
    Filed: June 18, 2024
    Publication date: October 10, 2024
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Amnon HOFFMAN, Abraham J. DOMB, Anna ELGART, Irina CHERNIAKOV
  • Minimally invasive subdural evacuating system
    Patent number: 12108965
    Abstract: The present invention provides minimally invasive subdural evacuating systems and methods of use thereof. The subdural evacuating systems include a cutting component and a rod component, wherein the rod component provides an external physical indicator that the surface of the dura mater has been reached, permitting the cutting component to accurately pierce the dura mater with minimal to no risk of damaging any adjacent anatomy.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: October 8, 2024
    Assignee: MUSC Foundation for Research Development
    Inventors: Stephen Kalhorn, Ryan Kellogg, Joe Ruscito
  • COMBINATION THERAPIES FOR THE TREATMENT OF DISEASES
    Publication number: 20240325461
    Abstract: Disclosed are combination therapies for the treatment of diseases including obesity and osteoporosis. In some embodiments, an inactivated Parabacteroides goldsteinii is enterically administered to a subject, such as a human patient, in combination with a bisphosphonate such as alendronate to treat the metabolic disease or disorder. Related pharmaceutical and probiotic compositions and methods are provided.
    Type: Application
    Filed: March 28, 2024
    Publication date: October 3, 2024
    Applicant: Research Development Foundation
    Inventors: Mirko TRAJKOVSKI, Melis ULGEN
  • METHODS AND COMPOSITIONS FOR USE IN IMPROVING ADAPTIVE IMMUNITY IN THE ELDERLY POPULATION
    Publication number: 20240325437
    Abstract: A method of increasing proliferation of adaptive immune cells of a subject at least 65 years old is provided. The method comprising contacting the immune cells with an agent which increases the level of labile iron in the immune cells and/or reduces toxicity of hemoglobin, heme or a degradation product thereof, thereby increasing the proliferation of the adaptive immune cells of the subject.
    Type: Application
    Filed: March 28, 2024
    Publication date: October 3, 2024
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Noga RON-HAREL, David EZUZ
  • Device for automatically inserting and manipulating a medical tool into and within a bodily lumen
    Patent number: 12102290
    Abstract: An assembly for driving linear movement and roll movement of an elongate surgical tool, comprising: an elongate shaft comprising a central lumen extending along the shaft long axis; the elongate shaft comprising a plurality of apertures extending across walls of the elongate shaft and into the central lumen; a set of wheels positioned opposing each other and aligned on two sides of the central lumen, the set of wheels at least partially extending through the apertures beyond the walls of the elongate shaft and into the central lumen to contact an elongate surgical tool received therein; the set of wheels being coupled to the elongate shaft and configured to rotate with the elongate shaft as a single unit when the elongate shaft is rotated about the shaft long axis.
    Type: Grant
    Filed: November 15, 2021
    Date of Patent: October 1, 2024
    Assignees: Microbot Medical Ltd., Technion Research & Development Foundation Limited
    Inventors: Simon Sharon, Idan Boader, Moshe Shoham, Eran Cohen, Eyal Morag
  • Surgical robotic arm control system and control method thereof
    Patent number: 12102393
    Abstract: A surgical robotic arm control system and a control method thereof are provided. The surgical robotic arm control system includes a surgical robotic arm, an image capturing unit, and a processor. The surgical robotic arm has multiple joint axes. The image capturing unit obtains a first image. The processor executes a spatial environment recognition module to generate a first environment information image, a first direction information image, and a first depth information image according to the first image. The processor executes a spatial environment image processing module to calculate path information according to the first environment information image, the first direction information image, and the first depth information image. The processor executes a robotic arm motion feedback module to operate the surgical robotic arm to move according to the path information.
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: October 1, 2024
    Assignee: Metal Industries Research & Development Centre
    Inventors: Jian Jia Zeng, Bo-Wei Pan, Sheng-Hong Yang
  • Intelligent thermal and power management in a wireless communications device in a wireless communications system (WCS)
    Patent number: 12101109
    Abstract: Intelligent thermal and power management in a wireless communications device in a wireless communications system (WCS) is disclosed. In a non-limiting example, the wireless communications device can be a base station (e.g., eNB) in the WCS. The wireless communications device includes a number of sensor circuits each configured to perform a sensory measurement (e.g., temperature measurement) in a specific circuit or at a specific location of the wireless communications device. A control circuit is provided in the wireless communications device support intelligent thermal and power management in the wireless communications device. Specifically, the control circuit determines that the sensory measurement is above an abnormal threshold(s) and performs one or more corrective actions accordingly to reduce the sensory measurement to a desirable threshold.
    Type: Grant
    Filed: May 27, 2022
    Date of Patent: September 24, 2024
    Assignee: Corning Research & Development Corporation
    Inventors: Lior Michael Kruh, Shirish Nagaraj, Deepak Pengoria, Hsien Li Woo
  • APPARATUS AND METHOD FOR ULTRA-FAST CRYSTALLIZATION IN PHASE - CHANGE RF SWITCHES
    Publication number: 20240313766
    Abstract: An indirectly heated phase change switch (IPCS) for radio frequency (RF) switching, comprises two RF ports and an RF path therebetween, a phase change material (PCM) located between the RF ports, an embedded heater separated from the PCM by a dielectric layer, the embedded heater configured to provide thermal actuation of the PCM to bring about phase changes between a crystalline state and an amorphous state to provide Ohmic switching, and a bias voltage on the IPCS across said RF path. The bias is provided during heating to improve the crystallization time.
    Type: Application
    Filed: February 15, 2022
    Publication date: September 19, 2024
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Shahar KVATINSKY, Nicolas WAINSTEIN, Eilam YALON
  • Haploid human embryonic stem cell lines and somatic cell lines and methods of making the same
    Patent number: 12091678
    Abstract: Haploid human embryonic stem cells and cell lines, haploid multipotent human cells, and haploid differentiated human cells are provided. In addition, methods of making and using the haploid human cells are provided.
    Type: Grant
    Filed: December 15, 2020
    Date of Patent: September 17, 2024
    Assignees: New York Stem Cell Foundation, Inc., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Dietrich M. Egli, Nissim Benvenisty, Ido Sagi
  • COMPOSITIONS AND METHODS FOR TREATING A MEDICAL CONDITION
    Publication number: 20240301090
    Abstract: Compositions and methods for treating a medical condition are provided. Accordingly, there is provided a composition comprising a polypeptide comprising a GnRH receptor binding protein and a polynucleotide coding a therapeutic agent, wherein said polypeptide is in association with said polynucleotide via a linker comprising a cleavage motif that can be cleaved by a proteolytic enzyme secreted by a cell expressing said GnRH receptor. Also provided is a nucleic acid construct comprising a nucleic acid sequence encoding a fusion protein comprising a DNA binding domain (DBD) of a transcription factor that binds a regulatory region of a gonadotropin gene attached to a chromatin modifying domain that represses transcription upon association with the DBD. Also provided are methods of use thereof.
    Type: Application
    Filed: July 13, 2022
    Publication date: September 12, 2024
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Philippa MELAMED, Lilach Pnueli POLINSKY
  • Laser cleaving and polishing of doped optical fibers
    Patent number: 12085755
    Abstract: The present disclosure relates to an optical fiber having a core and a cladding, where the cladding is doped with a dopant. The cladding has a dopant concentration gradient in the radial direction such that a concentration of the dopant changes with respect to radial distance from a core-cladding interface. Doping the cladding of the optical fiber enables ablation of the fiber surface with a line source to provide an ablated wedge or crack such that cleaving can be achieved by applying a stress force to the fiber after ablation or by applying a pull force during ablation.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: September 10, 2024
    Assignee: Corning Research & Development Corporation
    Inventors: Anthony Sebastian Bauco, Kevin Wallace Bennett, Eric Raymond Logan
  • Fiber optic connectors with funnel-shaped boots and methods of installing the same
    Patent number: 12078850
    Abstract: A fiber optic connector comprises a connector body, a ferrule, and a boot. The ferrule has a rear portion supported within the connector body and a front portion extending beyond a front end of the connector body. The boot has a front portion within the connector body and a funnel-shaped portion that extends beyond a back end of the connector body. The funnel-shaped portion defines a boot back end. Additionally, the funnel-shaped portion includes a tapered passage on an interior of the boot and a lip on an exterior of the boot. The tapered passage and the lip are curved toward each other proximate the boot back end so that the funnel-shaped portion terminates with a rounded configuration.
    Type: Grant
    Filed: September 13, 2021
    Date of Patent: September 3, 2024
    Assignee: Corning Research & Development Corporation
    Inventors: Victor Julian Borer, Albert De Los Santos, Donald Kent Larson, Edward B. Lurie, Jameson Rensloe Wright, Donald Allen Zielinski, Jr.
  • Front bumper insert
    Patent number: D1046715
    Type: Grant
    Filed: April 14, 2022
    Date of Patent: October 15, 2024
    Assignees: Zhejiang ZEEKR Automobile Research & Development Co., Ltd., Zhejiang Geely Holding Group Co., Ltd.
    Inventor: Asok George