Patents Assigned to Research Development
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Patent number: 4894455Abstract: Zinc(II) complexes in which at least one ligand is provided by a compound being:(1) 3-hydroxy-4-pyrone or a 3-hydroxy-4-pyrone in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by an aliphatic hydrocarbon group of 1 to 6 carbon atoms; or(2) a 3-hydroxypyrid-2-one or 3-hydroxypyrid-4-one in which the hydrogen atom attached to the nitrogen atom is replaced by an aliphatic acyl group, by an aliphatic hydrocarbon group of 1 to 6 carbon atoms, or by an aliphatic hydrocarbon group substituted by one or, except in the case of ionizable groups, more than one substituent selected from aliphatic acyl, alkoxy, aliphatic amine, aliphatic amide, carboxy, aliphatic ester, halogen, hydroxy and sulpho groups and, optionally, in which one or more of the hydrogen atoms attached to ring carbon atoms are replaced by one of said substituents, by an aliphatic hydrocarbon group of 1 to 6 carbon atoms, or by an aliphatic hydrocarbon group substituted by an alkoxy, aliphatic ester, halogen or hydroType: GrantFiled: February 18, 1987Date of Patent: January 16, 1990Assignee: National Research Development CorporationInventors: Robert C. Hider, George Kontoghiorghes, Jack Silver, Michael A. Stockham
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Patent number: 4892468Abstract: A hydraulic pump is disclosed, characterized in that, in the hydraulic pump including a cylinder body having a cylinder chamber, a suction port and an ejection port, a cam member and a reciprocatingly movable member are provided, wherein oil in said cylinder chamber is ejected when said movable member is pushed into said cylinder chamber by the cam member, a cylindrical piston is slidably fitted into said cylinder chamber, so that the movable member is engaged with the cylindrical piston when it is pushed into the cylinder chamber so shut off communication between the cylinder chamber and the suction port and a valve provided in the ejection passage communicating to said ejection port is opened due to the pressure rise when said movable member is further pushed into said cylinder chamber to eject the oil in the cylinder chamber outwardly.Type: GrantFiled: August 8, 1988Date of Patent: January 9, 1990Assignees: Akebono Brake Industry Co., Ltd., Akebono Research, Development Centre Ltd.Inventor: Toshifumi Maehara
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Patent number: 4892846Abstract: A fibre-reinforced ceramic material is made by making a melt of glass of specified composition, cooling the melt rapidly enough for it to solidify as a glass, crushing the glass to a particle size not exceeding 70 .mu.m but preferably not exceeding 50 .mu.m mixing the powder with reinforcing fibres and heat-treating the mixture, preferably under pressure. The glass composition is: 100 parts by weight of base glass (0-30 CaO, 0-30 MgO, 5-35 Al.sub.2 O.sub.3, and 35-75 SiO.sub.2) plus 1/2-3 parts Cr.sub.2 O.sub.3 plus 1/2-10 parts of Fe.sub.2 O.sub.3 or the equivalent.This ensures the ceramic contains both surface-nucleated and internally-nucleated crystals, enhancing its properties.Type: GrantFiled: November 17, 1988Date of Patent: January 9, 1990Assignee: National Research Development CorporationInventors: Philip S. Rogers, Rees D. Rawlings, Hyung S. Kim
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Patent number: 4892478Abstract: A method of producing dental appliances, especially orthodontic appliances, but also including dentures and other dental prosthesis. The method includes placing a self-merging dental gel especially as a stream on a dental cast and under and around preformed dental parts mounted on the cast and merging the dental gel into a homogeneous form of the complete part and then curing the formed dental appliance. The dental gel is a colloidal system including a hardenable dispersing medium, a colloid and a catalyst, preferably a photoinitiator.Type: GrantFiled: March 21, 1988Date of Patent: January 9, 1990Assignee: Dentsply Research & Development Corp.Inventors: Louis H. Tateosian, Louis C. Souder
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Patent number: 4892481Abstract: A dental composite carrier and a packaging means for a composite used for posterior restorations in a tooth is provided. The composite carrier comprises a handle having a lever with a jaw on one end, and the package comprises individual incremental portions of composite material contained in ampules, and a number of ampules packaged in a tray. The composite carrier is used to pick an ampule out of the tray, carry it to a tooth, and deliver it into a cavity in the tooth. Optionally, the handle may have a condenser on its opposite end to be used for packing and smoothing the composite in the tooth.Type: GrantFiled: July 6, 1988Date of Patent: January 9, 1990Assignee: Dentsply Research & Development Corp.Inventors: Thomas V. Kopunek, Douglas D. Bennett
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Patent number: 4891102Abstract: A method of determining one gas in the presence of another, where the one gas is reactive with an electrochemical product of the other, comprisesapplying the gases to one side of a membrane permeable to the two gases, the other side of the membrane retaining a solvent for both gases and for the electrochemical product,applying, for the predetermined duration through a working electrode in contact with the solvent, a potential which electrolyses (e.g. reduces) the (dissolved) other gas to form the said electrochemical product,applying, through the working electrode, a potential for reconverting the product to the dissolved gas,measuring, at a predetermined instant or integrated over a predetermined time slot, the current flowing at the reconversion potential, and,from the amount by which the measured current (or integrated current, i.e. charge) falls short of the current when the said one gas is absent, determining the concentration of the said one gas.Type: GrantFiled: April 23, 1987Date of Patent: January 2, 1990Assignee: National Research Development CorporationInventors: Wyndham J. Albery, Anthony J. M. Coombs, Humphrey J. J. Drummond, Clive Hahn
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Patent number: 4891582Abstract: An optical apparatus and method for measuring the diffusion length in an insulating photoconductor or a semiconductor sample material, that includes a source of coherent light; means for splitting the light source and providing transmitted and reflected beams each having a variable light intensity, one of the transmitted and reflected beams being incident as a background beam at a location on the sample material, means for directing the other of the transmitted and reflected beams so as to be incident at the location as a probe beam, the directing apparatus establishing a predetermined angle between the background and probe beams at the location, polarizing means disposed in the path of the background beam and having one of two predetermined orientations corresponding to polarized and non-polarized states of the beam passing therethrough, means disposed in the path of the probe beam for periodically blocking the passage thereof; and means for measuring changes in the periodic photocurrent supplied by a powerType: GrantFiled: May 3, 1989Date of Patent: January 2, 1990Assignee: Technion Research & Development FoundationInventors: Kurt Weiser, Elia Zeldov, Dan Ritter
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Patent number: 4891593Abstract: An image of the distribution of the molecules of a paramagnetic substance in solution obtained by exciting EPR resonance in the solute and obtaining an NMR image of selected nuclei (e.g. protons) in the solvent.Type: GrantFiled: August 4, 1988Date of Patent: January 2, 1990Assignee: National Research Development CorporationInventors: John Lurie, David M. Bussell, John R. Mallard
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Patent number: 4891587Abstract: A magnetic field sensor including a body of amorphous magnetic material [C] and means to propagate ultrasound [A.B.D.] in said body together with means [E,F; PD, PSD, F] to detect variation with ambient magnetic field strength in the effect of the body on the propagation of ultrasound therein. The ultrasound is propagated as zero-mode shear wave, said mode being controlled by having the thickness of the body of amorphous magnetic material below a critical value which is the quotient of velocity divided by frequency. A specific magnetic field [G,J; G,M] can be applied to control the operating point of the sensor. The field can be alternating and the effect on propagation detected by a phase detector followed by a phase sensitive detector.Type: GrantFiled: November 3, 1988Date of Patent: January 2, 1990Assignee: National Research Development CorporationInventor: Patrick T. Squire
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Patent number: 4891614Abstract: The invention relates to matching asymmetrical discontinuites in transmission lines to give low reflection coefficients (less than five percent) over a wide frequency band (corresponding to at least an octave in wavelength). A group of asymmetrical discontinuites, such as impedance steps in a waveguide, are matched by considering a reference plane whose position varies with frequency at which the reflection coefficient for waves transmitted in one direction is equal to that for waves transmitted in the opposite direction. Matching elements are then provided which have a reflection coefficient at the reference plane which is equal and opposite to the reflection coefficient of the discontinuities. Matching is less difficult if the distance between the steps is less than a quarter of a guide wavelength at all frequencies in the wide band mentioned above and such an arrangement is a "reduced quarterwave transformer".Type: GrantFiled: May 28, 1987Date of Patent: January 2, 1990Assignee: National Research Development CorporationInventor: Frans C. De Ronde
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Patent number: 4889803Abstract: Interferon .gamma. is produced in highly purified form (activity exceeding 10.sup.8 units/ml-day) by CHO cells cotransformed by a first plasmid bearing the genomic human interferon gene under the control of the SV40 early promoter, and a second plasmid bearing a DHFR gene under similar control. Methotrexate selection yielded a clone which was a particularly efficient producer. Production of interferon .gamma. may also be facilitated by a Harvey sarcoma virus enhancer sequence.Type: GrantFiled: April 26, 1985Date of Patent: December 26, 1989Assignee: Yeda Research & Development Co., Ltd.Inventors: Michel Revel, Menachem Rubinstein, Yvez Mory
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Patent number: 4890117Abstract: In view of the introduction of cellular radio, there is a requirement for an antenna of simple construction which can be sold in a consumer market. While the invention meets this need it also has application to the problem of providing TM.sub.01 to TE.sub.01 made converters. The invention employs radial conductors printed on a dielectric substrate and aligned with the transverse electric field in a waveguide supporting the TM.sub.01 mode. Circumferential conductors, each coupled to one of the radial conductors, act as monopoles radiating the required field in an antenna where the radial conductors project through apertures in the waveguide. For the mode converter, both radial and circumferential conductors are inside the waveguide, with the radial conductors aligned with the transverse electric field of the TM.sub.01 mode. Arrangements for maximizing the field at the position of the radial and circumferential conductors are described as are means for preventing the propagation of unwanted modes.Type: GrantFiled: January 14, 1988Date of Patent: December 26, 1989Assignee: National Research Development CorporationInventor: Frans C. de Ronde
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Patent number: 4888814Abstract: A pattern recognition system comprises first and second cell blocks each composed of a number of nonlinear oscillators arranged in a multi-layer matrix. The nonlinear oscillators in each layer of the first cell block are coupled so as to be excited by a corresponding bit of a two-dimensional bit pattern, and are coupled to adjacent nonlinear oscillators in the same layer so as to mutually emphasize the oscillation in a predetermined direction different from those predetermined for the other layers, so that in each of the layers, there are selectively excited the nonlinear oscillators corresponding to a continuous line segment contained in the bit pattern and aligned in the excitation emphasizing direction of that layer.Type: GrantFiled: February 23, 1989Date of Patent: December 19, 1989Assignee: Research Development Corporation of JapanInventors: Youko Yamaguchi, Hiroshi Shimizu
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Patent number: 4887034Abstract: The detection of compounds containing both nuclei of a kind which exhibit nuclear magnetic resonance (nmr) and nuclei of a kind which exhibit nuclear quadrupole resonance (nqr), for example compounds containing both .sup.1 H and .sup.14 N nuclei, is carried out by subjecting a substance suspected of containing such a compound to a magnetic field and repetitively to three parallel activities A,H and B. Activity A comprises two similar rf pulse sequences P.sub.A and P.sub.B at the nmr frequency. Activity H is a temporary change in the value of the magnetic field, which may be a reduction to zero. Activity B is the application of additional rf signals. Activity H and/or activity B are different during each of the respective pulse sequences P.sub.A and P.sub.B. The activity B rf signals are at one or more frequencies selected so that in combination with the activity H in at least one of the pulse sequences the subsequent nmr signal is modified if such a compound is present.Type: GrantFiled: January 26, 1988Date of Patent: December 12, 1989Assignee: National Research Development CorporationInventor: John A. S. Smith
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Patent number: 4886545Abstract: This invention provides compositions comprising a compound having the structural formula ##STR1## wherein each X, Y and Z may represent oxygen, sulfur or two hydrogen atoms, provided however that, when Z represents two hydrogen atoms, both X and Y represent oxygen or sulfur and when Z represents oxygen or sulfur at least one of X and Y must represent oxygen or sulfur; m is 2-6; R' is H or a lower alkyl group having 1-4 carbon atoms; n is 0-17 and R is --CH.sub.3, ##STR2## wherein R" is H or halogen. The invention also provides compositions comprising a physiologically-active agent and the hereinabove recited 1-substituted azacycloalkane compound in an amount effective to enhance the penetration of the physiologically-active agent through the skin or other membrane of the body of an animal.Type: GrantFiled: July 23, 1987Date of Patent: December 12, 1989Assignee: Nelson Research & Development CompanyInventors: James V. Peck, Gevork Minaskanian
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Patent number: 4886783Abstract: This invention relates to a method for administering systemically active agents including therapeutic agents through the skin or mucosal membranes of humans and animals in a transdermal device or formulation comprising topically administering with said systemic agent an effective amount of a membrane penetration enhancer having the structural formula ##STR1## wherein each X, Y and Z may represent oxygen, sulfur or two hydrogen atoms, provided however that, when Z represents two hydrogen atoms, both X and Y represent oxygen or sulfur and when Z represents oxygen or sulfur at least one of X and Y must represent oxygen or sulfur; m is 2-6; R' is H or a lower alkyl group having 1-4 carbon atoms; n is 0-16 and R is --CH.sub.3, ##STR2## wherein R" is H or halogen.Type: GrantFiled: August 17, 1988Date of Patent: December 12, 1989Assignee: Nelson Research & Development Co.Inventors: Gevork Minaskanian, James V. Peck
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Patent number: 4885308Abstract: This invention provides a method for treating the symptoms of parkinsonism which comprises administering to a human or other mammal suffering from the symptoms of parkinsonism an effective amount of a compound selected from the group consisting of optically-active or racemic compounds represented by the general formula: ##STR1## wherein R.sub.1 is selected from the group consisting of organic radicals methyl, substituted or unsubstituted phenyls, pyridyl, hydroxyphenyl, ##STR2## X is oxygen or sulfur, Y is selected from the group consisting of hydroxy, nitro, cyano, azido, amino, acylamino, carboxyamido, trifluoromethyl, sulfate, sulfonamido, halogen, hydrocarbyl and hetero atom-substituted hydrocarbyl radicals, wherein said heteroatoms are selected from the group consisting of halogen, nitrogen, oxygen, sulfur and phosphorus and said hydrocarbyl radicals comprise from 1 to 12 carbon atoms. and a is an integer of from zero to 3,R.sub.2, R.sub.3 and R.sub.Type: GrantFiled: June 13, 1988Date of Patent: December 5, 1989Assignee: Nelson Research & Development Co.Inventor: Alan S. Horn
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Patent number: 4884329Abstract: A precision automatic assembly apparatus for inserting an insertable part into a hole formed in a member includes a movable hand incorporating a movable body to which the insertable part is attached, and an electromagnetic wrist mechanism having a plurality of electromagnets for supporting the movable body and controlling the movable body along a plurality of axes. When the part is inserted into the hole formed in the member, an external force which acts upon the part and the position of a point at which the part contacts the member are estimated by a control unit via position sensing means incorporated in the hand. Currents supplied to the excitation coils of the electromagnetic devices are controlled on the basis of the estimate to adjust the state (position and attitude) of the insertable part, whereby the part is fitted into the hole smoothly and automatically.Type: GrantFiled: April 13, 1987Date of Patent: December 5, 1989Assignee: Research Development CorporationInventor: Toshiro Higuchi
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Patent number: 4885344Abstract: Polymeric materials useful as positive resists comprise a backbone formed from an addition polymer which is degradable by radiation and at least 3 pendant polymeric groups which show no appreciable positive resist characteristics. Preferably these materials comprise a backbone which is a polymethacrylate ester and from 3 to 5 pendant polystyrene groups. These polymers exhibit increased sensitivity and resistance to plasma processing and provide resists which are useful as components of integrated circuits.Type: GrantFiled: January 19, 1988Date of Patent: December 5, 1989Assignee: National Research Development CorporationInventors: Stanley Affrossman, Massoud Bakhshaee, Richard A. Pethrick, David C. Sherrington
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Patent number: 4882837Abstract: A precision automatic assembly apparatus for inserting an insertable part into a hole formed in a member includes a movable hand incorporating a movable body to which the insertable part is attached, and an electromagnetic wrist mechanism having a plurality of electromagnetic devices including air core coils and magnetic poles for supporting the movable body and controlling the movable body along a plurality of axes. When the part is inserted into the hole formed in the member, an external force which acts upon the part and the position of a point at which the part contacts the member are estimated by a control unit via position sensing means incorporated in the hand. Currents supplied to the excitation coils of the electromagnetic devices are controlled on the basis of the estimate to adjust the state (position and attitude) of the insertable part, whereby the part is fitted into the hole smoothly and automatically.Type: GrantFiled: April 22, 1988Date of Patent: November 28, 1989Assignee: Research Development CorporationInventor: Toshiro Higuchi