Patents Assigned to Research Foundation of The City University of New York
  • Publication number: 20180230372
    Abstract: Self-suspending proppants including proppant particles coated with a CO2-philic coating are provided. The CO2-philic coating may be lightly crosslinked and may have a physical structure that constrains CO2 molecules. Methods of making self-suspending proppants may include coating a proppant particle with a polymerizable precursor material of a CO2-philic material and polymerizing the polymerizable precursor material to form a self-suspending proppant are also provided. Additionally, hydraulic fracturing fluids that may include a CO2-based fluid and the self-suspending proppants and methods of treating subterranean formations by contacting a subterranean formation with hydraulic fracturing fluid and propagating at least one subterranean fracture are provided.
    Type: Application
    Filed: March 15, 2018
    Publication date: August 16, 2018
    Applicants: Aramco Services Company, Research Foundation of The City University of New York
    Inventors: Feng Liang, Ghaithan A. Al-Muntasheri, Leiming Li, B. Raghava Reddy, George John, Vidyasagar Adiyala
  • Publication number: 20180230371
    Abstract: Self-suspending proppants including proppant particles coated with a CO2-philic coating are provided. The CO2-philic coating may be lightly crosslinked and may have a physical structure that constrains CO2 molecules. Methods of making self-suspending proppants may include coating a proppant particle with a polymerizable precursor material of a CO2-philic material and polymerizing the polymerizable precursor material to form a self-suspending proppant are also provided. Additionally, hydraulic fracturing fluids that may include a CO2-based fluid and the self-suspending proppants and methods of treating subterranean formations by contacting a subterranean formation with hydraulic fracturing fluid and propagating at least one subterranean fracture are provided.
    Type: Application
    Filed: March 15, 2018
    Publication date: August 16, 2018
    Applicants: Aramco Services Company, Research Foundation of The City University of New York
    Inventors: Feng Liang, Ghaithan A. Al-Muntasheri, Leiming Li, B. Raghava Reddy, George John, Vidyasagar Adiyala
  • Patent number: 10036042
    Abstract: A method for isomerizing a double bond is provided. A substrate is exposed to an isomerase enzyme, wherein the isomerase enzyme comprises a redox-regulated ligand switch and heme b cofactor. A reducing agent is added which changes iron (III) to iron (II). The enzyme isomerizes double bonds in the iron (II) state but not in the iron (III) state. In one embodiment, the enzyme is homologous with 15-cis-?-carotene isomerase (Z-ISO).
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: July 31, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Eleanore T. Wurtzel, Jesús Beltrán
  • Patent number: 10023555
    Abstract: The present invention discloses novel compounds derived from NSAIDs and pharmaceutically acceptable salts thereof. Other aspects of the invention relate to use of the NSAID derivatives in treating inflammatory diseases and pharmaceutical compositions thereof.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: July 17, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Khosrow Kashfi, Mitali Chattopadhyay, Ravinder Kodela
  • Patent number: 10004898
    Abstract: A system and method to treat neuromuscular conditions, including spinal cord injury, by what is characterized as dipole (two point) cortico-muscular stimulation. Two-point stimulation, with oppositely charged electrodes, allows pulsed, direct current to pass through the cortico-muscular pathway. The electrodes are placed on nerves, muscles, or a combination of both, that are on opposite sides of the spinal column, forming a current that passes across the spinal column. Further, an active electrode can be placed on the spinal column and a reference electrode can be placed outside the central nervous system. These methods improve functional recovery of the motor pathway.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: June 26, 2018
    Assignee: THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Zaghloul Ahmed, Andrzej Wieraszko
  • Patent number: 9987818
    Abstract: A method for forming a superhydrophobic surface is disclosed. A surface of a first substrate is bonded to a surface of a second substrate to form a stacked material. The stacked material is peeled apart to form a fracture line and provide a superhydrophobic surface.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: June 5, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Alan M. Lyons, QianFeng Xu
  • Patent number: 9974951
    Abstract: A system and method to treat neuromuscular conditions, including spinal cord injury, by what is characterized as dipole (two point) cortico-muscular stimulation. Two-point stimulation, with oppositely charged electrodes, allows pulsed, direct current to pass through the cortico-muscular pathway. The electrodes are placed on nerves, muscles, or a combination of both, that are on opposite sides of the spinal column, forming a current that passes across the spinal column. Further, an active electrode can be placed on the spinal column and a reference electrode can be placed outside the central nervous system. These methods improve functional recovery of the motor pathway.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: May 22, 2018
    Assignee: THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Zaghloul Ahmed, Andrzej Wieraszko
  • Patent number: 9956395
    Abstract: An electrode assembly includes a substantially porous element configured to be coupled to an electrode for delivery of electrical current to a patient in a neurostimulation procedure. The substantially porous material defining a contact surface, of which at least a portion contacts the patient during the neurostimulation procedure. A first insulating member is coupled to the substantially porous element and exposed at the contact surface to prevent a portion of the contact surface from contacting the patient to deliver the electrical current during the neurostimulation procedure.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: May 1, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Marom Bikson, Gregory Kronberg, Tamer N. Naguib, Denis Arce, Preet Minhas
  • Patent number: 9952227
    Abstract: Fluorescent proteins (Chlopsid FP I from Kaupichthys hyoproroides and Chlopsid FP II from Kaupichthys n. sp.) are used in a method for detecting bilirubin. The proteins are based on transcriptome analysis of the false moray eels, Kaupichthys hyoproroides and Kaupichthys n. sp., the later representing a heretofore undescribed species.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: April 24, 2018
    Assignees: Research Foundation of the City University of New York, John B. Pierce Laboratory
    Inventors: David F. Gruber, Jean P. Gaffney, Vincent A. Pieribone
  • Patent number: 9942031
    Abstract: A system for producing a public ring that is fully homomorphically encrypted. The system comprises a processor which generates a first presentation G of a ring, where G=x,y|x2=0,y2=0,xy+(p+1)yx=1, where x and y are generators and p is a first private prime number. The system further generates a second presentation H of the ring. H is defined as follows: H=x,y,t|x2=0,y2=0,t=m1yx,xy+m2yx+t=1. In addition, m1 and m2 are positive integers and p+1=m1+m2, wherein t is a generator and the first presentation G and the second presentation H are isomorphic. The system further produces a public ring ? that is fully homomorphically encrypted, where: H ^ = ? x , y , t ? N · 1 = 1 , x 2 = 1 , y 2 = 0 , xyx = x , yxy = y , tx = 0 , yt = 0 , t 2 = t + m 2 2 - m 2 m 1 ? tyx ? , N=pq and further, q is a second private prime number, and the public ring ? is further, publically available. A corresponding method is also disclosed.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: April 10, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Delaram Kahrobaei, Ha T. Lam, Vladimir Shpilrain
  • Patent number: 9927604
    Abstract: A method for tracking three-dimensional movement of an object and focusing thereon is provided. Software repeatedly detects three-dimensional locations of one or more objects and image quality by sampling images at many parameter settings as the objects move in three-dimensional environment. The images are ranked occurring to a fitness score and parameter settings for subsequent images to established using a biologically-inspired algorithm.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: March 27, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: M. Umit Uyar, Stephen Gundry
  • Patent number: 9909113
    Abstract: In one embodiment, the invention provides a method of purifying recombinant alpha-galactosidase A. The method includes obtaining a lysate from cells recombinantly expressing alpha-galactosidase A grown in a cell culture medium having non-precipitating phosphate; contacting said lysate with a first chromatography media that binds ?-D-mannopyranosyl or ?-D-glucopyranosyl; eluting alpha-galactosidase A from the first chromatography media to generate a first eluate having alpha-galactosidase A, wherein said eluting includes at least one elution pause between 4 and 16 hours; contacting the first eluate with a second chromatography media that binds galactose binding proteins; and eluting alpha-galactosidase A from said second chromatography media to generate a second eluate containing said recombinant alpha-galactosidase A.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: March 6, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: David H. Calhoun, Abass Abdullahi
  • Patent number: 9889185
    Abstract: The subject matter disclosed herein pertains to the modulation of a bacterial invasion switch and the subsequent use of the bacterium to vaccinate an organism. In one embodiment, the bacterial invasion switch is modulated by changing the proteolysis of ExoR protein. In another embodiment, a mutated bacterium produces a mutant ExoR protein that resists proteolysis.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: February 13, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Haiping Cheng, Shari Walcott, Haiyang Lu, Li Luo, Menghua Yang, Zahra Salehi
  • Patent number: 9867542
    Abstract: A time reversal optical tomography (TROT) method for near-infrared (NM) diffuse optical imaging of targets embedded in a highly scattering turbid medium is presented. TROT combines the basic symmetry of time reversal invariance and subspace-based signal processing for retrieval of target location. The efficacy of TROT is tested using simulated data and data obtained from NIR imaging experiments on absorptive, scattering and fluorescent targets embedded in Intralipid-20% suspension in water, as turbid medium, as well as, a realistic cancerous model breast assembled using ex vivo human breast tissues with two embedded tumors. The results demonstrate the potential of TROT for detecting and locating small targets in a turbid medium, such as, breast tumors in early stages of growth.
    Type: Grant
    Filed: October 22, 2013
    Date of Patent: January 16, 2018
    Assignee: Research Foundation of the City University of New York
    Inventors: Binlin Wu, Wei Cai, Swapan K. Gayen
  • Publication number: 20170368474
    Abstract: A method and device for extracting oil from food waste is disclosed. Food waste is introduced into an elongated cylinder that is immersed under hot water. A drive shaft is actuated that simultaneously presses the food waste against an interior wall and moves the food waste through the cylinder. The content of the cylinder is subjected to steam treatment using a steam inlet in the cylinder. The combination of hot water, steam treatment and pressing recovers a high content of oil from the food waste.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 28, 2017
    Applicant: Research Foundation of the City University of New York
    Inventor: Lawrence M. Pratt
  • Patent number: 9849101
    Abstract: A method for enhancing amidohydrolase activity of Fatty Acid Amide Hydrolase (FAAH) is disclosed. The method comprising administering a phenoxyacyl-ethanolamide that causes the enhanced activity. The enhanced activity can have numerous effects on biological organisms including, for example, enhancing the growth of certain seedlings.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: December 26, 2017
    Assignees: Research Foundation of the City University of New York, The Curators of the University of Missouri, University of North Texas
    Inventors: George John, Subbiah Nagarajan, Kent Chapman, Lionel Faure, Peter Koulen
  • Patent number: 9845472
    Abstract: PVT1 exon 9 is overexpressed in aggressively tumorigenic prostate cancer cell lines and prostate tumor tissues. This exon provides a diagnostic tool for the detection and monitoring of aggressive prostate cancer. Several small interfering ribonucleic acids (siRNAs) are disclosed that are useful for treating prostate cancer.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: December 19, 2017
    Assignee: Research Foundation of the City University of New York
    Inventors: Olorunseun O. Ogunwobi, Adeodat Ilboudo, Chunxiao Ying
  • Patent number: 9844668
    Abstract: Improved neuromodulation control of neurological abnormalities associated with effector organs in vertebrate beings using direct current stimulation for modulating spinal cord excitability, having a peripheral-current supplying component for providing direct current peripheral nerve stimulation and a spinal-current supplying component providing direct current for spinal stimulation, and a controller managing such functions.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: December 19, 2017
    Assignee: The Research Foundation of the City University of New York
    Inventor: Zaghloul Ahmed
  • Patent number: 9832998
    Abstract: The present invention relates to novel antiviral compounds which are covalently attached to solid, macro surfaces. In another embodiment, the invention relates to novel antiviral compositions including a polymeric material and, embedded therein, an antiviral compound. In other embodiments, the invention relates to making a surface antiviral and making a polymeric material antiviral.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: December 5, 2017
    Assignees: Research Foundation of the City University of New York, Long Island University, Pace University
    Inventors: Robert Engel, JaimeLee Iolani Rizzo, Karin Melkonian-Fincher
  • Publication number: 20170333872
    Abstract: The invention is directed to an adsorbent comprising: a) 20-30% porous carbon with incorporated organic nitrogen species; and b) 70-80% inorganic matter. The invention is directed to a method of making an adsorbent which comprises: a) thermally drying dewatered sewage sludge to form granulated organic fertilizer; and b) pyrolyzing said the organic fertilizer at temperatures between 600 and 1000° C. The invention is additionally directed to the process of removing acidic gases from wet air streams comprising putting an adsorbent in contact with the wet air stream and allowing the adsorbent to adsorb the acidic gases.
    Type: Application
    Filed: August 4, 2017
    Publication date: November 23, 2017
    Applicant: Research Foundation of the City University of New York
    Inventors: Teresa J. BANDOSZ, Andriy Bahryeyev, David C. Locke