Abstract: An isolated recombinant influenza virus is provided having PA, PB1, PB2, NP, NS, M, NA and HA viral segments, wherein the PB1 viral segment encodes a PB1 with a residue other than isoleucine at position 711 or the M viral segment encodes a M1 with a residue other than methionine at position 128, wherein the recombinant influenza virus has enhanced replication relative to a corresponding influenza virus having a PB1 viral segment that encodes a PB1 with an isoleucine at position 711 or having a M viral segment that encodes a M1 with methionine at position 128, as well as methods of making and using the virus.

Abstract: Disclosed herein are a continuous scanning method using signal shielding and an apparatus for the continuous scanning method. The continuous scanning method includes producing a magnetic field on consecutively input samples by applying a signal to an excitation solenoid coil, blocking signal detection in a partial region so that only one harmonic peak is detected by a detection solenoid coil, which is a differential coil, using a magnetic field produced by at least one magnet, and sequentially detecting one harmonic peak in the samples based on the detection solenoid coil, and performing scanning of nanomagnetic particles on respective samples based on a signal for the detected harmonic peak.

Abstract: The present invention discloses a novel microbial process for decontaminating (per)chlorate and/or nitrate containing matrices. A heterotrophic mixed microbial culture expressing the functional genes responsible for (per) chlorate and nitrate reduction is the major component of the process. The present process can be a better substitute for existing processes for decontaminating perchlorate contaminated propellant wastewater, ion exchange resin/regenerate solutions, etc. The consortium consists or comprises of Halomonas sp. NIIST-PRB-02 (MTCC No. 5911), Bacillus sp. NIIST-PRB-03 (MTCC No. 5912) and Serratia marcescens strain NIIST5 (MTCC No. 5821).

Abstract: The present invention provides a compound having the structure:

Abstract: This document provides methods and materials involved in identifying and/or treating mammals having a treatment-resistant prostate cancer (e.g., an enzalutamide-resistant, castration-resistant prostate cancer). For example, methods and materials for identifying a mammal (e.g., a human) having treatment-resistant prostate cancer (e.g., an enzalutamide-resistant, castration-resistant prostate cancer) as having an elevated level of one or more polypeptides (e.g., one or more of a CXXC5, a CXXC4, a TET2, an ID1, an ID3, and/or a PFN2 polypeptide) in treatment-resistant prostate tissue are provided. Methods and materials for administering one or more targeted therapies with or without one or more chemotherapeutic agents to a mammal having treatment-resistant prostate cancer identified as having an elevated level of one or more polypeptides (e.g., one or more of a CXXC5, a CXXC4, a TET2, an ID1, an ID3, and/or a PFN2 polypeptide) in treatment-resistant prostate tissue also are provided.

Abstract: A method of forming a probe, wherein the method includes converting cholenic acid into a compound with a terminal alkyne group, wherein the converting the cholenic acid comprises using a sequence, wherein the sequence comprises synthesizing a THP-protection group, LiAlH4 reduction, Dess-Martin oxidation, and Seyferth-Gilbert-Bestmann homologation. The method additionally includes forming A-Chol by removing the THP-protection. Further, the method includes forming PhA-Chol from the compound with the terminal alkyne group via a palladiumcatalyzed Sonogashira reaction. Additionally, the method includes forming PhDY Chol from the compound with the terminal alkyne group via a coppercatalyzed Cadiot-Chodkiewicz reaction.

Abstract: A noise management system for a window includes an active noise control (ANC) module and a passive sound absorbing module. The ANC module is disposed in or adjacent a ventilation channel of the window and configured to substantially cancel low-frequency noise entering the ventilation channel. The passive sound absorbing module is disposed in or adjacent to the ventilation channel and configured to absorb both high-frequency noise entering the channel and harmonic sounds generated by the ANC module.

Abstract: The present invention provides nanoparticle conjugates incorporating the self-assembling module diphenylalanine (FF) dipeptide into a bioactive moiety. The conjugate self-assembles to form distinct nanometric structures such as nanospheres. The present invention further provides nanoparticles formed by supramolecular co-assembly of the conjugates with a diphenylalanine (FF) dipeptide or analog thereof, to generate bioactive self-assembled nanostructures.

Abstract: Provided is a method for transmitting paging information in a cellular system. An object of the method is transmitting paging information which can improve applicability of a limited radio resource by variably and flexibly setting up and mapping a transport channel and a physical channel in order to transmit information notifying start of downlink information from a base station to a terminal in a cellular system for packet transmission. The method includes the steps of: forming a paging channel (PCH) in a transport channel corresponding to generation of paging information; setting a paging indication channel (PICH) based on the paging information and forming the paging indication channel in a radio resource of a physical layer; and allocating the paging channel to the radio resource of the physical layer.

Abstract: A hologram display device includes a light source unit that emits light, a spatial light modulator that modulates the light emitted from the light source unit, and a random pinhole panel. The random pinhole panel includes a plurality of pinholes of a random position or a random size and is arranged in line with an output part of the spatial light modulator. In the hologram display device and the method of manufacturing the hologram display device, a position and size of a random pinhole on the random pinhole are not limited to inside each pixel of the spatial light modulator.

Abstract: An apparatus for supporting a wafer during a plasma processing operation includes a pedestal configured to have bottom surface and a top surface and a column configured to support the pedestal at a central region of the bottom surface of the pedestal. An electrical insulating layer is disposed over the top surface of the pedestal. An electrically conductive layer is disposed over the top surface of the electrical insulating layer. At least three electrically conductive support structures are distributed on the electrically conductive layer. The at least three support structures are configured to interface with a bottom surface of a wafer to physically support the wafer and electrically connect to the wafer. An electrical connection extends from the electrically conductive layer to connect with a positive terminal of a direct current power supply at a location outside of the pedestal.

Abstract: In some embodiments, a method for aiding prediction of the likelihood of progression from Barrett's esophagus to high grade dysplasia or esophageal adenocarcinoma in a subject, is disclosed. The method can include (a) providing an oesophagal sample from said subject (b) determining if said sample stains abnormally with Aspergillus oryzae lectin; (c) determining if there is a DNA content abnormality in said sample; and (d) determining if there is low grade dysplasia in said sample; wherein if (b) is abnormal and (c) is abnormal and low grade dysplasia is present, then an increased likelihood of progression is determined. The disclosed subject matter also relates to an apparatus, and to different uses of certain materials.

Abstract: An ultra-sensitive speckle-analyzing system is disclosed which includes an image capture device configured to receive a scattered field having a speckle configuration and thereby capture i) a reference speckle image, and ii) a subsequent speckle image, each of the reference and the subsequent speckle images having a plurality of speckles on a background; and a processor configured to generate a cross-correlation between the plurality of speckles of the reference and the subsequent speckle images, to thereby represent a change in the speckle configuration.

Abstract: Methods of preparing influenza viruses having altered immunodominant epitopes in HA, e.g., having one or more residues in one or more of antigenic sites A-E in HA altered, and viral vectors, e.g., influenza virus VLPs or non-influenza viruses or VLPs thereof expressing or having influenza HAs with altered immunogenicity as a result of altered immunodominant epitopes therein are provided.

Abstract: The present invention relates to a composition for immunostaining cleared large tissues and a method for immunostaining cleared large biological tissues using the same. The composition for immunostaining cleared large tissues increases antibody permeability in cleared biological tissues, in particular, large biological tissues having a thickness of 3 mm or more, to allow antibodies to penetrate deep into thick tissues, thereby overcoming immunostaining problems associated with limited permeation of antibodies in existing methods, reduces the time required for immunostaining large tissues, thereby enabling simple and rapid three-dimensional bioimaging with high resolution for large biological tissues, and may be beneficially used, through structure images, for identifying the causes of various diseases, developing new treatment methods, and predicting the efficacy and toxicity of drugs.

Abstract: A method and apparatus for setting up a relay link to transfer a data frame using a relay in a wireless communication system are provided. The relay link setup method of a source STA in a wireless communication system may include receiving capability information of at least one relay supporting station included in the wireless communication system from an access point (AP) or a personal basic service set (PBSS) central point (PCP), selecting one of the at least one relay supporting station as a relay station, using beam forming information among the source station, a destination station, and the at least one relay supporting station and the capability information, transferring a relay link setup request frame to the destination station, and receiving a relay link setup response frame that includes information on a relay link setup result from the destination station. The relay link setup request frame and the relay link setup response frame may pass through the relay station.

Abstract: Methods are provided for the prevention and/or treatment of pain, interstitial cystitis and/or overactive bladder in a subject using an IPSE protein, such as H03 H-IPSE, H06 H-IPSE, M-IPSE or other IPSE homologs, variants, mutants or mimics. The IPSE protein can be administered prior to, contemporaneously with, and/or after the subject develops pain, interstitial cystitis and/or overactive bladder. Pharmaceutical compositions also are provided that contain one or more IPSE proteins in a pharmaceutically acceptable carrier, excipient or diluent.

Abstract: Systems and methods for determining a pose of an object held by a flexible end effector of a robot are disclosed. A method of determining a pose of the object includes receiving tactile data from tactile sensors, receiving curvature data from curvature sensors, determining a plurality of segments of the flexible end effector from the curvature data, assigning a frame to each segment, determining a location of each point of contact between the object and the flexible end effector from the tactile data, calculating a set of relative transformations and determining a location of each point relative to one of the frames, generating continuous data from the determined location of each point, and providing the continuous data to a pose determination algorithm that uses the continuous data to determine the pose of the object.

Abstract: A solid particle aerosol development device form fogs of solid (e.g., frozen) fountain solution particles that are charged, and brings the charged solid fountain solution particles into proximity of an electrostatic charged image pattern on a imaging member's charge retentive surface. The charged solid fountain solution particles bond to the charge retentive surface at the charged image pattern to develop that image into a fountain solution latent image. The solid particle aerosol development devices produce solid fountain solution particles to develop electrostatic latent images while mitigating issues of evaporation and vapor production, and thus may apply fine films of fountain solution which may otherwise evaporate. In examples, the fountain solution aerosol development devices may include an anilox member, a metering member in contact with the anilox member, a fountain solution reservoir, a particle charger and a particle delivery baffle.