Patents Assigned to Research
  • Compositions and methods for nasal administration of drugs to brain and for systemic effect
    Patent number: 11389404
    Abstract: The invention relates to a nasally administrable composition comprising at least one active substance in magnesium-containing vesicular carrier, said carrier comprising glycol, phospholipids, water and at least one magnesium source. Methods for nasal administration of the composition, for example, for pain relief, are also provided.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: July 19, 2022
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Elka Touitou, Hiba Natsheh
  • Growth media for three-dimensional cell culture
    Patent number: 11390835
    Abstract: A three-dimensional cell growth medium is described. The cell growth medium may comprise hydrogel particles swollen with a liquid cell growth medium to form a granular gel yield stress material which undergoes a phase transformation from a solid phase to a liquid-like phase when an applied stress exceeds the yield stress. Cells may be placed in the three-dimensional cell growth medium according to any shape or geometry, and may remain in place within the three-dimensional cell growth medium.
    Type: Grant
    Filed: May 7, 2016
    Date of Patent: July 19, 2022
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Wallace Gregory Sawyer, Thomas Ettor Angelini, Steven Craig Ghivizzani, Tapomoy Bhattacharjee, Glyn Daniel Palmer
  • Promoters and uses thereof
    Patent number: 11390866
    Abstract: The present invention relates to a nucleic acid sequence derived from the regulatory region of the human gamma-synuclein gene and having a promoter activity in retinal ganglion cells. The present invention also relates to expression cassettes or vectors comprising said promoter operably linked to a nucleic acid sequence encoding a polypeptide of interest as well as viral particles or host cells comprising said expression cassette or vector. The present invention also relates to the use of said expression cassettes, vectors, viral particles or cells in the treatment of ocular disease, in particular ocular disease associated with retinal ganglion cell or photoreceptor cell degeneration.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: July 19, 2022
    Assignees: SORBONNE UNIVERSITÉ, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Deniz Dalkara, Serge Picaud, Melissa Desrosiers, Jose-Alain Sahel, Jens Duebel, Alexis Bemelmans, Botond Roska
  • Multi-step process and system for converting carbon dioxide to multi-carbon products
    Patent number: 11390954
    Abstract: Systems and methods for the electrochemical conversion of COT to multi-carbon products are provided. Each system and method comprises a sequence of multiple, independently optimized electrochemical reaction steps that take place in separate reaction chambers.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: July 19, 2022
    Assignee: University of Louisville Research Foundation, Inc.
    Inventor: Joshua Spurgeon
  • Electroporation delivery systems and methods of using electroporation delivery systems
    Patent number: 11389642
    Abstract: The present disclosure relates generally to electroporation systems and utilizing algorithms for electroporation pulse delivery including a patient's EKG/EGM monitoring. In some embodiments, an electroporation delivery system may include an electrocardiogram operatively connected to a processing device and a memory. One or more sensors may be operatively connected to the electrocardiogram for measuring electrical activity QRS complex of a patient's heart. One or more electrodes for treatment may be disposed in, at, or near the patient's heart, the one or more electrodes operatively connected to a pulse delivery mechanism. The electroporation delivery system may be configured to determine whether an electroporation pulse is deliverable to a patient based on the electrocardiogram.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: July 19, 2022
    Assignees: Cardiac Pacemakers, Inc., Mayo Foundation for Medical Education and Research
    Inventors: Samuel J. Asirvatham, Suraj Kapa, Sarah M. Gruba, Douglas D. Pagoria, James P. Rohl, Chance M. Witt, Ammar M. Killu, Niyada Naksuk
  • Compositions for use as lubricants in die casting, methods of using the same, and products produced therewith
    Patent number: 11390824
    Abstract: Lubricant compositions and methods of producing die-cast products by applying such a lubricant composition to a working surface of a die prior to casting a product from a molten metal injected into the die. The composition serves as lubricant between the die and resulting product, and contains at least one active component that reacts with an oxide of the metal to remove a layer of the oxide that forms on a surface of the melt during the die casting process.
    Type: Grant
    Filed: January 28, 2019
    Date of Patent: July 19, 2022
    Assignee: Purdue Research Foundation
    Inventors: Xiaoming Wang, Qingyou Han
  • Hafnium-zirconium oxide (HZO) ferroelectric transducer and method of making the same
    Patent number: 11393973
    Abstract: A nano-mechanical acoustical resonator is designed and fabricated with CMOS compatible techniques to apply to mm-wave RF front-ends and 5G wireless communication systems which have extreme small scale and integrated in 3D sensors and actuators.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: July 19, 2022
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Mayur Ghatge, Glen H. Walters, Toshikazu Nishida, Roozbeh Tabrizian
  • WIRELESS CHARGING SYSTEM FOR SMART GARMENTS SUPPORTING MULTIPLE CHARGING METHODS
    Publication number: 20220224153
    Abstract: A contactless charging system for smart garments having coils whose centroids are not colinear. Folding a coil in half through its centroid will null out its inductance. A smart garment having 3 coils that have centroids that are not colinear is proposed. Accordingly, there is no single folding line that intersects all 3 centroids thereby nullifying inductance. Power can be combined with one or more rectifiers such that power is not cancelled. The present disclosure is suitable for any charging environment or apparatus, such as, drawer or hanger.
    Type: Application
    Filed: January 14, 2022
    Publication date: July 14, 2022
    Applicants: Analog Devices, Inc., UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Patrick RIEHL, Chin-Wei CHANG, Jenshan LIN
  • APPARATUS FOR ENCODING AND DECODING IMAGE BY SKIP ENCODING AND METHOD FOR SAME
    Publication number: 20220224896
    Abstract: The present invention relates to an apparatus and method for encoding and decoding an image by skip encoding. The image-encoding method by skip encoding, which performs intra-prediction, comprises: performing a filtering operation on the signal which is reconstructed prior to an encoding object signal in an encoding object image; using the filtered reconstructed signal to generate a prediction signal for the encoding object signal; setting the generated prediction signal as a reconstruction signal for the encoding object signal; and not encoding the residual signal which can be generated on the basis of the difference between the encoding object signal and the prediction signal, thereby performing skip encoding on the encoding object signal.
    Type: Application
    Filed: April 1, 2022
    Publication date: July 14, 2022
    Applicants: Electronics and Telecommunications Research Institute, Kwangwoon University Industry-Academic Collaboration Foundation, Universily-lndustry Cooperation Group of Kyung Hee University
    Inventors: Sung Chang LIM, Ha Hyun LEE, Se Yoon JEONG, Hui Yong KIM, Suk Hee CHO, Jong Ho KIM, Jin Ho LEE, Jin Soo CHOI, Jin Woong KIM, Chie Teuk AHN, Dong Gyu SIM, Seoung Jun OH, Gwang Hoon PARK, Sea Nae PARK, Chan Woong JEON
  • HIGH TEMPERATURE THERMAL DUAL-BARRIER COATING
    Publication number: 20220221234
    Abstract: A thermal dual-barrier coating system is disclosed which includes a first thermal barrier layer having a first thermal conductivity, one or more composite structures vertically disposed adjacent the first thermal barrier layer, each of the one or more composite structures includes an ultra-thin disordered semi-continuous metallic film and a layer of a second thermal barrier layer.
    Type: Application
    Filed: January 11, 2022
    Publication date: July 14, 2022
    Applicant: Purdue Research Foundation
    Inventors: Jacob ZUBIN, Xueji WANG, Ali JISHI, Avra Sankar BANDYOPADHYAY
  • MULTI-BEAM ANTENNA USING HIGHER-ORDER MODES
    Publication number: 20220224005
    Abstract: Disclosed is an array antenna comprising a plurality of array elements. The plurality of array elements are formed as a coupler including a central element and peripheral elements configured to surround the central element; each of the central element and the peripheral elements is formed as a waveguide; and the peripheral elements are excited in higher-order modes using coupling slots to form a beam pattern through an electric field distribution of the central element and the peripheral elements.
    Type: Application
    Filed: January 13, 2022
    Publication date: July 14, 2022
    Applicant: Electronics and Telecommunications Research Institute
    Inventor: So Hyeun YUN
  • GASTRORETENTIVE DOSAGE FORMS FOR SUSTAINED DRUG DELIVERY
    Publication number: 20220218604
    Abstract: The present disclosure is directed to floating gastroretentive dosage forms with prolonged gastric residence time. The disclosure also provides rapidly expanding sustained release or combined immediate release and sustained release formulations comprising drugs that require targeted release in the proximal gastrointestinal tract for maximum therapeutic benefit. The rapidly expanding floating gastroretentive dosage forms comprise a permeable elastic membrane providing desired characteristics for drug release and mechanical strength to maintain tablet integrity.
    Type: Application
    Filed: March 24, 2022
    Publication date: July 14, 2022
    Applicant: AMNEAL COMPLEX PRODUCTS RESEARCH LLC
    Inventors: Kanji Meghpara, Jaydeep Vaghashiya, Navnit H. Shah, Dipen Desai, Wantanee Phuapradit, Harpreet Kaur Sandhu, Siva Ram Kiran Vaka, Namdev B. Shelke, Ashish Chatterji
  • MIXED-PHASE WINDING, STATOR, AND MOTOR
    Publication number: 20220224181
    Abstract: Disclosed is a mixed-phase winding, comprising at least one branch, where each branch is composed of at least one coil ring; the coil ring comprises a set of lap winding coils and a set of combined conductors; each set of lap winding coils comprises P lap winding coils evenly distributed in the circumferential direction, and each set of combined conductors comprises P combined conductors evenly distributed in the circumferential direction, P being the number of pole pairs; and the lap winding coils and the combined conductors are arranged at intervals in a staggered manner in the circumferential direction and sequentially connected in series; each lap winding coil and each combined conductor each comprises a hairpin conductor or at least two hairpin conductors arranged side by side in the thickness direction; each hairpin conductor comprises a hairpin body integrally bent in a U shape.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 14, 2022
    Applicants: CHONGQING ZONGSHEN ELECTRIC POWER TECHNOLOGY CO. LTD, CHONGQING ZONGSHEN INNOVATION TECHNOLOGY RESEARCH INSTITUTE CO. LTD
    Inventors: Chaodong HUANG, Junshan SHAO
  • METHOD FOR MANUFACTURING POWER SEMICONDUCTOR DEVICE
    Publication number: 20220223696
    Abstract: Disclosed is a method for manufacturing a power semiconductor device. The method includes forming a lower active layer on a substrate, forming an upper active layer on both sides of the lower active layer, forming a source electrode, a drain electrode, and a gate electrode on the upper active layer and the lower active layer, and forming a heat dissipating and electrical ground electrode penetrating the substrate and the lower active layer and connected to a lower surface of the lower active layer. The upper active layer may be epitaxially grown at a high doping concentration by a selective deposition method using a mask layer that exposes a portion of the lower active layer as a blocking layer.
    Type: Application
    Filed: January 12, 2022
    Publication date: July 14, 2022
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Jae Kyoung MUN, Woojin CHANG, Yoo Jin JANG, Kyu Jun CHO
  • A METHOD FOR BIOLOGICALLY PRODUCING SUGAR ALCOHOL FROM AGAR
    Publication number: 20220220490
    Abstract: The present invention relates to a method for biologically producing, from seaweeds, 3,6-anhydro-L-galactitol (L-AHGol) which is a novel sugar alcohol, and agarobititol (ABol) which is in a disaccharide form having 3,6-anhydro-L-galactitol (L-AHGol) as a reducing end, by using a genetic engineering technique in GRAS strains.
    Type: Application
    Filed: September 5, 2019
    Publication date: July 14, 2022
    Applicant: Korea University Research and Business Foundation
    Inventors: Kyoung Heon KIM, Yong Su JIN, Dong-Hyun KIM, Eun-Ju YUN
  • LAMINATING AND SHAPING COPPER POWDER, LAMINATED AND SHAPED OBJECT, MANUFACTURING METHOD OF LAMINATED AND SHAPED OBJECT, AND LAMINATING AND SHAPING APPARATUS
    Publication number: 20220219232
    Abstract: The present invention provides a laminating and shaping copper powder capable of shaping a laminated and shaped object of copper having a high electrical conductivity of, for example, 80% IACS or more. The present invention is a laminating and shaping copper powder obtained by mixing a nano-oxide of equal to or more than 0.01 wt % and equal to or less than 0.20 wt % and a pure copper powder. There is also provided a laminated and shaped object using the laminating and shaping copper powder of the present invention. There are also provided a manufacturing method of the laminated and shaped object using the laminating and shaping copper powder of the present invention and a laminating and shaping apparatus using the laminating and shaping copper powder.
    Type: Application
    Filed: June 4, 2020
    Publication date: July 14, 2022
    Applicants: FUKUDA METAL FOIL & POWDER CO.,LTD., TECHNOLOGY RESEARCH ASSOCIATION FOR FUTURE ADDITIVE MANUFACTURING
    Inventors: Yuji SUGITANI, Hideki KYOGOKU
  • SUBSTRATE-ENHANCED COMPARATOR AND ELECTRONIC DEVICE
    Publication number: 20220224320
    Abstract: The present disclosure provides a substrate-enhanced comparator and electronic device, the comparator including: a cross-coupled latch, for connecting input signals to the gate of a cross-coupled MOS transistor to form a first input of the latch; output buffers, connected to the cross-coupled latch for amplifying output signals of the latch; AC couplers, connected to the output buffers for receiving and amplifying the output signals of the latch, coupling the output signals to substrates of the cross-coupled MOS transistors to form second inputs of the latch. The cross-coupled latch is also for output signal regenerative latching based on input signals sampled at the first inputs and input signals sampled at the second inputs. The present disclosure introduces additional substrate inputs to the cross-coupled structure of the conventional latch as the second inputs of the latch.
    Type: Application
    Filed: January 7, 2020
    Publication date: July 14, 2022
    Applicants: NO.24 RESEARCH INSTITUTE OF CHINA ELECTRONICS TECHNOLOGY GROUP CORPORATION, Chongqing GigaChip Technology Co., Ltd.
    Inventors: Ting LI, Zhengbo HUANG, Yong ZHANG, Yabo NI, Jian'an WANG, Guangbing CHEN, Dongbing FU, Zicheng XU
  • INTERFERON REGULATORY FACTOR 5 INHIBITORS AND USES THEREOF
    Publication number: 20220220168
    Abstract: Polypeptides comprising a cell penetrating amino acid sequence and an interferon regulatory factor 5 (IRF5) targeting amino acid sequence are disclosed, where the IRF5 targeting amino acid sequence is one or more of RHATRHG (SEQ ID NO:1), KSRDFRL (SEQ ID NO:2) and GPRDMPP (SEQ ID NO:3), as well as methods of using these polypeptides to treat diseases, such as autoimmune and inflammatory diseases.
    Type: Application
    Filed: May 4, 2020
    Publication date: July 14, 2022
    Applicant: THE FEINSTEIN INSTITUES FOR MEDICAL RESEARCH
    Inventors: Betsy J. Barnes, Shan Sun
  • INTEGRATED DUAL-SIDED ALL-IN-ONE ENERGY SYSTEM INCLUDING PLURAL VERTICALLY STACKED DUAL-SIDED ALL-IN-ONE ENERGY APPARATUSES
    Publication number: 20220223777
    Abstract: The present disclosure relates to an integrated dual-sided all-in-one energy system including a plurality of vertically stacked dual-sided all-in-one energy apparatuses, each including an energy-harvesting device and an energy-storage device disposed on both sides of a substrate, and according to one embodiment of the present disclosure, an integrated dual-sided all-in-one energy system may include a plurality of dual-sided all-in-one energy apparatuses, each including an energy-harvesting device that is formed as an electrode pattern on one side of a substrate and generates electrical energy by harvesting energy based on a temperature difference between a first side and a second side and an energy-storage device that is formed on the other side of the substrate and is selectively connected to the energy-harvesting device based on the electrode pattern to store the generated electrical energy.
    Type: Application
    Filed: July 1, 2021
    Publication date: July 14, 2022
    Applicant: Korea University Research and Business Foundation
    Inventors: Sang Sig KIM, Kyoung Ah CHO, Yoon Beom PARK
  • ROBUST CARBON DOTS (CD) AS AN ARTIFICIAL TRACER FOR GROUNDWATER STUDIES
    Publication number: 20220220848
    Abstract: The invention provides methods for the measurement of ground water characteristics. The carbon dot tracer is injected in an injection bore well. Carbon dot tracer and ground water are thoroughly mixed in the injection bore well. The ground water mixed with carbon dot tracer is pumped from the injection bore well to an acquiring bore well connected with injection bore well with micro and major fracture; the water samples mixed with carbon dot tracer were collected at the acquiring bore well. The characteristics of the ground water were measured by measuring fluorescence. The invention further relates to a method for depicting the solute transportation in the soil.
    Type: Application
    Filed: January 11, 2021
    Publication date: July 14, 2022
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Taufique WARSI, Lopamudra BHATTACHARJEE, Thangamani SUPPAN, Sanjeev K. JAT, Kallol MOHANTA, Rama Ranjan BHATTACHARJEE, Rangarajan RAMASWAMY, Chakravadhanula MANIKYAMBA, T. Vinoda RAO, Virendra Mani TIWARI