Abstract: Provided are methods and compositions for cartilage repair. The method involves performing a surgical procedure at the site of a cartilage defect and administering a composition comprising a receptor for hyaluronan mediated motility (RHAMM)-mimetic peptide, and a high molecular weight hyaluronan.
Type:
Grant
Filed:
August 19, 2015
Date of Patent:
October 22, 2019
Assignees:
New York University, London Health Sciences Centre Research Inc.
Inventors:
Mary K. Cowman, Thorsten Kirsch, Eric J. Strauss, Eva Ann Turley, Cornelia Toelg, Leonard G. Luyt
Abstract: A bit interleaver, a bit-interleaved coded modulation (BICM) device and a bit interleaving method are disclosed herein. The bit interleaver includes a first memory, a processor, and a second memory. The first memory stores a low-density parity check (LDPC) codeword having a length of 16200 and a code rate of 2/15. The processor generates an interleaved codeword by interleaving the LDPC codeword on a bit group basis. The size of the bit group corresponds to a parallel factor of the LDPC codeword. The second memory provides the interleaved codeword to a modulator for 256-symbol mapping.
Type:
Grant
Filed:
May 21, 2015
Date of Patent:
October 22, 2019
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Sung-Ik Park, Sun-Hyoung Kwon, Bo-Mi Lim, Jae-Young Lee, Heung-Mook Kim, Nam-Ho Hur
Abstract: Provided is a charged particle generation device. The charged particle generation device includes a light source unit configured to emit a laser, a target layer that receives the laser and emits charged particles, and a focusing structure disposed on the target layer to focus the laser. The focusing structure includes solid films extending on an upper surface of the target layer in a direction away from the target layer, and a pore section disposed between the solid films and having a porous structure. The focusing structure includes a material having a higher atomic number than carbon.
Type:
Grant
Filed:
September 11, 2018
Date of Patent:
October 22, 2019
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Methods of pre-densifying a metal wire containing superconductor materials are provided. Superconductor materials containing the pre-densified wires also are provided. The wires may be pre-densified by subjecting a metal wire that includes one or more filament cavities in which a superconductor precursor powder is disposed to a temperature and a first pressure for a time sufficient to densify the superconductor precursor powder to form a pre-densified metal wire, wherein the temperature is less than the melting point of the superconductor precursor powder, and the first pressure is sufficient, at the temperature, to compress at least a portion of the metal wire.
Type:
Grant
Filed:
July 27, 2016
Date of Patent:
October 22, 2019
Assignee:
Florida State University Research Foundation, Inc.
Inventors:
Maxime R. Matras, Eric Hellstrom, Ulf Trociewitz, Jianyi Jiang, David Larbalestier
Abstract: A method of constraining operation of a robot includes receiving, using network interface hardware of a robot, one or more robotic control instructions from a user, where the robotic control instructions instruct the robot to perform a robotic movement, determining whether the user providing the one or more robotic control instructions to the robot is a primary user or a secondary user, and comparing the robotic movement instructed by the one or more robotic control instructions with one or more robotic operation constraints. The method further includes determining whether the robotic movement instructed by the one or more robotic control instructions conflicts with the one or more robotic operation constraints and constraining operation of the robot when the user is the secondary user and the robotic movement instructed by the one or more robotic control instructions conflicts with the one or more robotic operation constraints.
Abstract: The present disclosure is concerned with benzo annulene compounds that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, chikungunya, Venezuelan equine encephalitis, dengue, influenza, and zika, using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Type:
Grant
Filed:
February 8, 2018
Date of Patent:
October 22, 2019
Assignee:
Southern Research Institute
Inventors:
Ashish Kumar Pathak, Syed Kaleem Ahmed, Corinne E. Augelli-Szafran, Joseph A. Maddry
Abstract: A computer aided diagnostic system and automated method to classify a kidney. Image data for a medical scan that includes image data of a kidney may be received. The kidney image data may be segmented from other image data of the medical scan. One or more iso-contours may be registered for the kidney image data, and renal cortex image data may be segmented from the kidney image data based on the one or more registered iso-contours. The kidney may be classified by analyzing one or more features determined from the segmented renal cortex image data using a learned model associated with the one or more features.
Type:
Grant
Filed:
February 23, 2018
Date of Patent:
October 22, 2019
Assignee:
University of Louisville Research Foundation, Inc.
Inventors:
Ayman S. El-Baz, Amy Dwyer, Rosemary Ouseph, Fahmi Khalifa, Ahmed Soliman, Mohamed Shehata
Abstract: Provided is a battery pack comprising a plurality of batteries; and a plurality of memories that correspond respectively to the batteries and that each record deterioration information of the corresponding battery. Each set of a battery and a corresponding memory may be formed integrally as a battery cell. As a result, the deterioration information of each battery cell can be known even after the battery pack is disassembled.
Type:
Grant
Filed:
July 3, 2015
Date of Patent:
October 22, 2019
Assignees:
ITOCHU Corporation, The Japan Research Institute, Limited
Abstract: An implantable subsystem includes multiple implantable neural probes disposed on a flexible substrate. Each neural probe is configured to magnetically stimulate brain neurons. Each probe includes an array of magnetic neural stimulators that magnetically stimulate neurons. Each probe also includes neural probe activation circuitry comprising thin film switches disposed on the flexible substrate. The thin film switches are electrically coupled to row and column activation lines and selectively activate the magnetic neural stimulators in response to neural stimulation activation signals carried on the activation lines.
Type:
Grant
Filed:
June 7, 2017
Date of Patent:
October 22, 2019
Assignee:
Palo Alto Research Center Incorporated
Inventors:
Bernard D. Casse, George Daniel, Jonathan Rivnay, Christopher Paulson, Robert Street
Abstract: Provided herein is a polymer having formula I: where m, n, and R1 are as defined herein, and the polymer has a number average molecular weight of the polymer of from 500 to 80,000 Daltons. Also provided herein are block copolymers of the polymer of formula I, as well as processes to make the polymer and block copolymers thereof.
Type:
Grant
Filed:
February 16, 2016
Date of Patent:
October 22, 2019
Assignee:
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Abstract: Method and system is described for enhanced subsea leak detection by using autonomous underwater vehicle (AUV) that is equipped with measurement components and navigation components. The method and system may include a one or more wireless communication components for navigation. Also, the method and system may include one or more sensors to detect leakage from a pipeline.
Abstract: Downhole gas separators, artificial lift systems including the downhole gas separators, hydrocarbon wells including the artificial lift systems, and methods of separating a gas from a liquid hydrocarbon within a hydrocarbon well. The downhole gas separators include an elongate outer housing that defines an enclosed volume, a fluid inlet port, and a gas outlet port. The downhole gas separators further include an elongate dip tube that extends within the enclosed volume, and the gas outlet port is configured to selectively provide fluid communication between the enclosed volume and an external region.
Type:
Grant
Filed:
August 24, 2016
Date of Patent:
October 22, 2019
Assignee:
ExxonMobil Upstream Research Company
Inventors:
Jason Y. Wang, Andrey A. Troshko, Scott R. Buechler, Michael C. Romer
Abstract: A Quadrature-In, Quadrature-Out (QIQO) clock divider divides by an odd divisor, such as three. An IQ input clock has in-phase and quadrature differential signals. Four stages of dynamic logic are arranged into a loop, with each stage output being one of four IQ output signals that have 90-degree phase separations. Each stage output drives the gates of a p-channel charging transistor and an n-channel discharging transistor of a next stage. Two p-channel charging logic transistors are in series between the next stage output and the p-channel charging transistor, and two n-channel evaluation transistors are in series between the next stage output and the n-channel discharging transistor. Different pairs of the four IQ input clock signals are applied to their gates. When the prior stage output is low, the stage output is charged. When the prior stage output is high, the stage output discharge timing is determined by the IQ signals.
Type:
Grant
Filed:
April 18, 2019
Date of Patent:
October 22, 2019
Assignee:
Hong Kong Applied Science and Technology Research Institute Company Limited
Abstract: Systems and methods are provided for producing upgraded raffinate and extract products from lubricant boiling range feeds and/or other feeds having a boiling range of 400° F. (204° C.) to 1500° F. (816° C.) or more. The upgraded raffinate and/or extract products can have a reduced or minimized concentration of sulfur, nitrogen, metals, or a combination thereof. The reduced or minimized concentration of sulfur, nitrogen, and/or metals can be achieved by hydrotreating a suitable feed under hydrotreatment conditions corresponding to relatively low levels of feed conversion. Optionally, the feed can also dewaxed, such as by catalytic dewaxing or by solvent dewaxing. Because excessive aromatic saturation is not desired, the pressure for hydrotreatment (and optional dewaxing) can be 500 psig (˜3.4 MPa) to 1200 psig (˜8.2 MPa).
Type:
Grant
Filed:
May 19, 2017
Date of Patent:
October 22, 2019
Assignee:
ExxonMobil Research and Engineering Company
Inventors:
Benjamin S. Umansky, Keith K. Aldous, James W. Gleeson, Edward J. Blok, Richard A. Demmin
Abstract: Embodiments of the invention provide a method of treating cancer, the method comprising providing a subject having cancer cells, and contacting the cancer cells with a therapeutically effective amount of a G2/M checkpoint inhibitor. Embodiments of the invention also provide a method of treating cancer in a subject, the method comprising the steps of: (a) receiving a sample of the cancer cells from the subject; (b) determining if at least a portion of the sample of the cancer cells is LKB 1 deficient; and (c) contacting the cancer cells with a therapeutically effective amount of a G2/M checkpoint inhibitor.
Type:
Grant
Filed:
November 25, 2015
Date of Patent:
October 22, 2019
Assignees:
Dignity Health, The Translational Genomics Research Institute
Inventors:
Timothy G. Whitsett, Jr., Landon J. Inge
Abstract: An image processing system includes a memory to store data indicative of benchmark feature vectors of benchmark images, an input interface to accept data indicative of a first feature vector of a first image and a second feature vector of a second image, and an output interface to render a similarity value between the first and the second images. The system includes a processor to determine the similarity using a first hyperplane separating the benchmark feature vectors from the first feature vector and a second hyperplane separating the benchmark feature vectors from the second feature vector. The processor determines a first normal vector to the first hyperplane as the difference between the first feature vector and the mean of the benchmark feature vectors. The processor determines an offset for the first hyperplane as the average of the maximum inner product of the benchmark feature vectors with the first normal vector and the inner product of the first feature vector with the first normal vector.
Type:
Grant
Filed:
October 6, 2017
Date of Patent:
October 22, 2019
Assignee:
Mitsubishi Electric Research Laboratories, Inc.
Abstract: The present invention relates to a novel phenonthroline based pincer complexes and process for preparation thereof. The present invention also provides a one pot process for the conversion of carbon dioxide to methanol in the presence of a molecularly defined pincer-type single-site Ru-catalyst and secondary amine. Further the present invention provides the use of phenonthroline based pincer complexes for the esterification of alcohols and hydrogenation of esters under mild conditions.
Type:
Grant
Filed:
February 10, 2016
Date of Patent:
October 22, 2019
Assignee:
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
Abstract: One embodiment provides a system that facilitates access control. During operation, the system generates, by a first mobile computing device associated with a first user, a request to record information of a second user associated with a second mobile computing device. In response to receiving, from the second mobile computing device, an acceptance of the request, the system records, by the first mobile computing device, the information of the second user based on recording-related preferences of the second user. In response to receiving, from the second mobile computing device, a rejection of the request, the system precludes the first mobile computing device from recording the information of the second user, thereby facilitating intuitive and socially aligned access control.
Type:
Grant
Filed:
March 8, 2017
Date of Patent:
October 22, 2019
Assignee:
PALO ALTO RESEARCH CENTER INCORPORATED
Inventors:
Victoria M. E. Bellotti, Shane P. Ahern
Abstract: The present disclosure is directed to a user interface for modifying preprogrammed relationships between a plurality of subsystems of a surgical system. The user interface may be presented on a system display screen. It includes one or more selectable triggering events shown on the display screen, with each of the one or more selectable triggering events identifying a subsystem condition that selectively occurs during a surgical procedure performed with the surgical system. The interface also includes a plurality of selectable responses to the one or more selectable triggering events. The selectable responses deviate from the preprogrammed relationships between subsystems of the surgical system.
Abstract: A lubricant composition improves a performance of reducing a formation of compressor deposit. The lubricant composition also ensures low temperature properties of the lubricant composition. The lubricant composition includes 14 mass % or more of a fraction having a boiling point of 500° C. to 550° C. and 5 mass % or more of a fraction having a boiling point of over 550° C.
Type:
Grant
Filed:
April 6, 2016
Date of Patent:
October 22, 2019
Assignees:
ExxonMobil Research and Engineering Company, Toyota Jidosha Kabushiki Kaisha
Inventors:
Takashi Honda, Ko Onodera, Kosuke Fujimoto