Abstract: Various embodiments may relate to a resonator. The resonator may include a support including a substrate portion, and a membrane portion extending from the substrate portion over a cavity. The resonator may also include a piezoelectric layer on the membrane portion. The resonator may further include an electrode on the piezoelectric layer. The substrate portion may include dopants of a first conductivity type. The membrane portion may include dopants of a second conductivity type different from the first conductivity type. A ratio of a thickness of the membrane portion to a combined thickness of the electrode and the piezoelectric layer may be above 3:1 for temperature compensation.

Abstract: A positive electrode active material for a lithium secondary battery, a manufacturing method thereof, and it is provided a positive electrode active material for a lithium secondary battery, comprising: a core containing a lithium nickel-based compound having a Ni content of 80 mol % or more; and a coating material positioned on at least a portion of the core surface; wherein, the coating material includes a first coating material containing at least one of group 5 elements and group 6 elements; and S; and a second coating material including B, LiOH, Li2CO3 and Li2SO4.

Abstract: One embodiment of the present invention provides a flame doping method. Specifically, the present invention provides a flame doping method, which does not significantly change crystallinity, does not damage a substrate even while applying a high temperature, is usable as a doping method suitable for mass production, is advantageous in a process difficulty and a cost compared to other doping processes (thermal diffusion and ion implantation), and has high process stability.

Abstract: A method of reducing symptoms of a neurodegenerative disease comprising administering an effective amount of cannabidiol to a subject in need thereof to improved cognitive function and ameliorated the pathophysiology of the neurodegenerative disease.

Abstract: The disclosure relates to modified orthopoxvirus vectors, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified orthopoxvirus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences and safety. The viruses we have discovered are also amenable to large scale manufacturing protocols.

Abstract: Provided are a device and method for tagging training data. The method includes detecting and tracking one or more objects included in a video using artificial intelligence (AI), when there is an object to be split in a result of tracking the detected objects, splitting the object in object units, and when there are identical objects to be merged among split objects, merging the objects.

Abstract: Provided are a device and method for evaluating performance of a wearable muscle enhancement device.

Abstract: Genetically modified CCNT1 and XPO1 genes encoding proteins that inhibit virus infection in cells. The genetically modified CCNT1 gene encodes a protein with a C261Y substitution with respect to the human CCNT1 protein. The genetically modified XPO1 gene encodes a protein with P411T, M412V, and/or F414S substitutions with respect to the human XPO1 protein. The genetically modified CCNT1 and XPO1 genes can be introduced in cells. The cells comprising the genetically modified CCNT1 and XPO1 genes can be introduced in a subject with a virus infection to treat the infection.

Abstract: The invention relates to antigen-binding molecules that specifically bind to MHC Class I DLA-12 antigen. In one embodiment, the antigen-binding molecule is an antibody that specifically binds to canine MHC Class I DLA-12 antigen. Chimeric molecules of the antibody conjugated to another heterologous moiety are also provided. In one embodiment, the heterologous moiety is monomethyl auristatin E (MMAE). A method of inhibiting cancer using the antibody or the chimeric molecule thereof is also provided. In another embodiment, the antibody-MMAE conjugate suppresses tumour development in a murine model of B cell lymphoma.

Abstract: Disclosed is a split computing device operating in a serverless edge computing environment. The split computing device includes a transceiver configured to receive resource information of a terminal from the terminal and to measure a data transmission rate between the terminal and the split computing device in a process of receiving the resource information of the terminal; and a splitting point deriver configured to determine a splitting point of a deep neural network (DNN) model for split computing and an activation status of a container instance for each of tail models of a DNN corresponding to the respective splitting points using the resource information of the terminal, the data transmission rate, and resource information of the split computing device.

Abstract: A method of generating an induced trophoblast stem cell (iTSC) from a human cell is provided. Accordingly there is provided a method comprising expressing within a human cell GATA3 and OCT4 transcription factors, under conditions which allow generation of an iTSC from the cell. Also provided is a method of rejuvenating and/or de-differentiating a human cell. Also provided are nucleic acid constructs, protein preparation, isolated human cells, human iTSCs, rejuvenated cells and de-differentiated cells.

Abstract: An electric aircraft according to an embodiment of the present invention comprises: a fuselage equipped with a power means, a front spar and a rear spar extending from the fuselage to an end of a wing, and a plurality of ribs extending from the rear spar to the front spar and coupled to the front spar and the rear spar, in which a plurality of solid state batteries are mounted in a plurality of individual spaces partitioned by the front spar, the rear spar, and the plurality of ribs, respectively, and the front spar and the rear spar are used as members for serial connection of the plurality of solid state batteries, and the plurality of ribs are used as members for parallel connection of the plurality of solid state batteries.

Abstract: Disclosed herein are a video decoding method and apparatus and a video encoding method and apparatus. In video encoding and decoding, multiple partition blocks are generated by splitting a target block. A prediction mode is derived for at least a part of the multiple partition blocks, among the multiple partition blocks, and prediction is performed on the multiple partition blocks based on the derived prediction mode. When prediction is performed on the partition blocks, information related to the target block may be used, and information related to an additional partition block, which is predicted prior to the partition block, may be used.

Abstract: A method and system for computing the geolocation of UEs in a communication system by using LEO satellites. The satellites in this method and system combine only the signals that are transmitted by the communicating endpoints with the information of time of arrival and ephemeris data. A minimum of three or four satellites, based on the method used for computing the geolocation, are required to receive and append the signals transmitted by a UE. An access server of an LBS provider uses the information in the signals to compute the geolocation coordinates of UEs of its client users. Similarly, a UE of a client can also compute the geolocation coordinates of an access server of an LBS provider; as a consequence, both can authenticate each other using a location-based access control method. As a result, both UE and access server can directly authenticate each other using a suitable immutable factor.

Abstract: The instant invention relates to seaweed extract compositions, processes for isolation, isolated active agents, and methods of treating disease, disorders and conditions in a subject, including, reactive oxygen species (ROS)-mediated diseases and diseases mediated through the activation of the Nrf2-ARE (antioxidant response element) pathway, including proliferative diseases and disorders, Alzheimer's disease, stroke, and certain diseases and disorders of aging and associated with aging and exposure, by use of the extracts, compounds, and compositions thereof.

Abstract: A method, an image processing apparatus, and a system for generating a road image by using two-dimensional map data are proposed. The method includes receiving, by an image processing apparatus, an input of the map data of a specific area, extracting, by the image processing apparatus, road geometry information and road attribute information of a road from the map data, determining, by the image processing apparatus, road object standard information matched with the road attribute information for at least one road element of the road, generating, by the image processing device, style information for the at least one road element on a basis of at least one of the road attribute information and the road object standard information, and applying, by the image processing apparatus, the style information to the road geometry information to generate a basic road image including the road and the at least one road element.

Abstract: The present disclosure relates to a method and a system for quantifying a biomarker of a biological tissue. Two spectral sub-intervals are determined from a plurality of images of the tissue acquired at discrete wavelengths within a main wavelength interval using an imaging sensor in a manner such that the combination of the image data in the at least two spectral sub-intervals are correlated with a clinical variable of interest. The tissue is illuminated using one or more light sources with wavelengths within the at least two spectral sub-intervals. A measurement is of the light reflected by the tissue is acquired using an imaging sensor; and a measure of the biomarker of the tissue is calculated using the acquired measurement. The main wavelength interval is broader than each of the at least two spectral sub-intervals and at least one spectral confounder causing a spectral variability of the acquired image is present in the tissue.

Abstract: Methods for controlling brain activity in a subject are described herein. An example method can include delivering a stimulus to the subject, wherein the stimulus induces neural activity in the subjects brain and modulates expression of at least one soluble mediator of cellular activity (such as, for example, a cytokine, chemokine, and/or growth factor) within the subject, and the stimulus is delivered to the subject for less than one hour.

Abstract: The invention provides methods of inhibiting the growth or metastasis of a cancer in a mammal by inhibiting a Ral GTPase in the mammal. The invention also provides small molecule inhibitors of Ral GTPases useful in the methods of the invention and pharmaceutical compositions containing the therapeutically effective compounds of the invention, and methods of using the same.

Abstract: Disclosed herein is a composition comprising a biologically active agent; a base oil; an additional oil that is soluble in the base oil with a partition coefficient for the biologically active molecule that is at least twice that of the base oil; where the base oil and the additional oil are present in the composition in an amount effective to reduce the amount of the biologically active agent in an aqueous phase to less than 80 wt % of the amount with just the base oil present in an otherwise identical composition at the same total oil loading; a non-ionic surfactant; and water.