Abstract: The invention provides methods of inhibiting the growth or metastasis of a cancer in a mammal by inhibiting a Ral GTPase in the mammal. The invention also provides small molecule inhibitors of Ral GTPases useful in the methods of the invention and pharmaceutical compositions containing the therapeutically effective compounds of the invention, and methods of using the same.

Abstract: An electrostatic chuck for a substrate processing system includes a monolithic body made of ceramic. A plurality of first electrodes are arranged in the monolithic body adjacent to a top surface of the monolithic body and that are configured to selectively receive a chucking signal. A gas channel is formed in the monolithic body and is configured to supply back side gas to the top surface. Coolant channels are formed in the monolithic body and are configured to receive fluid to control a temperature of the monolithic body.

Abstract: The present disclosure relates to a leveling control method, device and system, a motor grader. The leveling control method includes: acquiring elevations of a current position of a blade of a motor grader and a target position, and a movement speed of the motor grader, wherein the target position is on the ground with a certain horizontal distance from the current position along a movement direction of the motor grader; determining a movement time of the blade from the current position to the target position from the horizontal distance and the movement speed; determining a lifting speed of a lifting cylinder from an elevation difference between the elevation of the target position and the elevation of the current position and the movement time; and controlling the lifting cylinder to adjust the blade to move from the current position to the target position according to the lifting speed.

Abstract: A display panel, including a pixel array; multiple rows of gate lines; and multiple columns of data lines; the gate lines and the data lines are perpendicular to each other, respectively, and every two gate lines are correspondingly connected to a row of sub-pixels, and each data line is correspondingly connected to two columns of sub-pixels; each row of pixels is correspondingly connected to two gate lines, and any two gate lines are parallel to each other; and there is a preset length difference between two adjacent rows of gate lines. The wiring of the display panel is convenient to be array detected, and improving the production yield of the display panel.

Abstract: A system and method for voice control of operating room electrical equipment. The system comprises an electrosurgical generator a controller with a memory, a graphical user interface controlled by said controller, a power module, a field programmable gate array, and a voice recognition module connected to said field programmable gate array, a data storage connected to said controller in said electrosurgical generator; and electrical operating room equipment connected to said voice recognition module, wherein said electrical operating room equipment is configured to receive and decrypt encrypted commands from said voice recognition module. The electrical operating room equipment may said electrosurgical generator or a robotic surgical system or other electrical equipment in an operating room. The connection between said electrical operating room equipment and said voice recognition module may be wireless.

Abstract: A user-wearable illumination assembly comprising eyeglass frames supporting a pair of lenses, a mounting structure on a bridge of the eyeglass frames, a headlamp removably coupled to the mounting structure, a battery housing removably coupled to the headlamp, and a battery inside the battery housing.

Abstract: Various embodiments relate to a method for producing a metal-organic framework (MOF) having a desired redox conductivity and including redox-active linkers, having ?-alkyl-ferrocene groups, via de novo solvothermal synthesis. Various embodiments relate to a metal-organic framework (MOF) linker comprising an ?-alkyl-ferrocene group. Various embodiments relate to a metal-organic framework (MOF), having a first plurality of redox-active linkers, each having an ?-alkyl-ferrocene group. The MOF according to various embodiments, may further have one or more redox-inactive linkers. Various embodiments relate to materials, apparatuses, and components that include the MOF according to various embodiments. For example, various embodiments relate to thin-films, bulk powders, or electrodes.

Abstract: A microspheric ionomer having a cross-linked structure, a preparation method therefor, applications thereof, and a preparation system thereof. The ionomer comprises structure units A represented by formula (1), structure units B represented by formula (2), and a cross-linking structure provided by a cross-linking agent, M being separately selected from H, a metal cation, and a straight chain, a saturated alkyl of branched or ring-shaped C1-C20, R being H or a methyl; and metal cations are introduced to part of structure units A in the ionomer. The ionomer shows an outstanding effect on nucleation of PET, serves as a nucleating agent for PET modification, so as to obtain a corresponding PET composition.

Abstract: The invention relates to a method for determining the microvascular resistance reserve, MRR, in the myocardium perfused by a normal or a stenotic coronary artery of a human patient, which method comprises the step of during rest condition of the patient: measuring the blood flow, Qrest, through the coronary artery; and further comprising the step of during rest condition or during maximum hyperemia of the patient: measuring the blood pressure, Pa, at a position proximal in the coronary artery or proximally of any stenosis, if present; and further comprising the steps of during maximum hyperemia of the patient: measuring the blood flow, Qmax, through the coronary artery; and measuring the blood pressure, Pd, at a position distal in the coronary artery or distally of any stenosis, if present, and wherein the microvascular resistance reserve, MRR, is determined by the additional step of calculating the microvascular resistance reserve as M ? R ? R = Q max Q rest ? P a P d , h ? y ? p ? e ? r

Abstract: Security techniques for device assisted services are provided. In some embodiments, secure service measurement and/or control execution partition is provided. In some embodiments, implementing a service profile executed at least in part in a secure execution environment of a processor of a communications device for assisting control of the communications device use of a service on a wireless network, in which the service profile includes a plurality of service policy settings, and wherein the service profile is associated with a service plan that provides for access to the service on the wireless network; monitoring use of the service based on the service profile; and verifying the use of the service based on the monitored use of the service.

Abstract: A method for preparing a COF-protected electrode and an electrode are provided. The method includes mixing an organic framework, a small molecular organic acid and a solvent, adding a polar aqueous solution containing a substrate thereto, mixing the above uniformly and heating the system at a low temperature under an inert atmosphere, filtering the solution to obtain precipitates, washing and drying the precipitates to obtain a COF film grown on a surface of the substrate; coating a protective layer on the COF film to obtain a substrate/COF/protective layer film; etching off the substrate to obtain a COF/protective layer film; and transferring the COF/protective layer film to a surface of the electrode, and removing the protective layer.

Abstract: A system comprising: at least one hardware processor; and a non-transitory computer-readable storage medium having stored thereon program instructions, the program instructions executable by the at least one hardware processor to: receive, as input, spectral image data representing spectral reflectance associated with at least one plant, calculate a first and second chlorophyll fluorescence indices in respective first and second wavelength bands, based, at least in part, on said spectral reflectance, and derive a quantum yield value with respect to said at least one plant, by: (i) dividing said first chlorophyll fluorescence index in a sum of said first and second chlorophyll fluorescence indices, and (ii) multiplying (i) by a vegetation index value associated with said at least one plant.

Abstract: A concentric tube steerable device includes a plurality of tubes having a nested, concentric configuration. The tubes include an outer tube and an inner tube that extends coaxially within the outer tube. The inner tube terminates at a tip, and a pose of the tip is effectuated through individual or collective rotation or translation of the tubes about a tube axis. The concentric tube steerable device includes an actuator for rotating at least one tube about a respective tube axis, and a translator for translating at least one tube along a respective tube axis. Each tube includes a precurved portion and a corresponding axis of precurvature. For at least one tube, a flexural rigidity of the tube along its axis of precurvature is less than a flexural rigidity of the tube along a second axis that is perpendicular to the axis of precurvature, thereby improving stability of the tube.

Abstract: Methods of using grids in connection with suitable microscopy techniques, such as for determining the structure of target compounds including proteins, are disclosed. Said grid comprising a coating modified with one or more capture agents and a deactivating agent.

Abstract: A staggered and crossed heat storage adsorption bed and a seawater desalination waste heat storage system are provided, which relate to the field of seawater desalination and the technical field of thermochemical adsorption heat storage. The adsorption bed includes a bed body, wherein an adsorption cavity is arranged in the bed body; two sides of the adsorption cavity are respectively communicated with an inlet cavity and an outlet cavity; the adsorption cavity includes a vacuum heat insulation layer arranged at an outermost side; the vacuum heat insulation layer is embedded with an adsorption box fixing layer; a corner end adsorption box, a central adsorption box and a side adsorption box are staggered and crossed arranged in an inner cavity of the vacuum heat insulation layer through the adsorption box fixing layer.

Abstract: The present invention provides a vapor-permeable flexible sensing platform unit comprising: a first porous membrane, wherein said membrane is substantially flexible and hydrophobic; and a volatile organic compounds (VOCs) sensor disposed on said membrane, the VOCs sensor comprising an electrode array and a conducting polymer porous film being in electric contact with said electrode array, wherein the VOCs sensor is insensitive to lateral strain. Further provided are a method of preparation of said platform unit and a lift-off, float-on (LOFO) method for the preparation of protonically doped polyaniline (PANI) thin films.

Abstract: A scent device comprises a container defining a volume and configured to hold a fill material, which may include one or more chemical compounds, natural formulations, or both configured to absorb odor and/or moisture, and/or emit a scent. The scent device includes a vented cap reversibly coupled to the container via a connection mechanism, and a breathable insert sandwiched between the container and the cap. The breathable insert may comprise a non-woven fabric supported along its perimeter by a structural mount. Methods of manufacturing the scent device involve cutting a mount from a support material, attaching a breathable material to the mount to form a breathable insert, depositing a scent-controlling material within a container, and sandwiching the breathable insert between the container and a cap upon coupling the cap with the container.

Abstract: Coronavirus S ectodomain trimers stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the coronavirus S ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to coronavirus in a subject. In additional embodiments, the therapeutically effective amount of the coronavirus S ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing coronavirus infection.

Abstract: The disclosure provides a method for monitoring a short-term voltage stability of a power system. The method includes: obtaining a topology and time series of a current power system; inputting the topology and the time series of the current power system into a trained spatial-temporal graph network model, the trained spatial-temporal graph network model being obtained by classification learning on a spatial-temporal graph network model based on a simulation sample dataset; outputting a status of the short-term voltage stability of the power system; and sending an alarm signal in response to outputting an unstable status of the short-term voltage stability of the power system.