Abstract: The present disclosure relates to a composition for preventing or treating fibrosis including an inhibitor of cyclin-dependent kinase 17 (CDK17) expression or activity. According to the present disclosure, the inhibitor of CDK17 expression or activity significantly reduces collagen production and cell activity and viability in activated hepatic stellate cells (liver fibrosis cell model), renal tubular epithelial cells (renal fibrosis cell model) in which fibrosis is induced by TGF-? treatment, and alveolar epithelial cells (lung fibrosis cell model) in which fibrosis is induced by TGF-? treatment, indicating that the composition of the present disclosure has an excellent effect in preventing or treating fibrosis.

Abstract: An additive manufacturing system comprising at least one electronic nose (e-nose) is provided. The e-nose may comprise a housing and gas sensors. The housing may have an air channel. The active sensor portion of the sensors are positioned in the air channel. The housing may be mounted to an extruder head of an additive manufacturing device. The system may also comprise a processor. The processor may determine whether there is an abnormality in an additive manufacturing process based on one or more combinations of outputs from the gas sensors received during the additive manufacturing process input into a deployed machine learning model; and generate a report for the additive manufacturing process containing the determination.

Abstract: Systems and methods for trajectory planning for an autonomous vehicle, may include: computing features for each of the plurality of candidate trajectories; computing scores for the features of the candidate trajectories, wherein the scores are based on parameter values associated with their corresponding final trajectories; determining, based on the computed scores, a trajectory of the candidate trajectories to be used as a warm-start trajectory for trajectory optimization and applying the warm-start trajectory to develop a final trajectory for the vehicle; and autonomously operating the autonomous vehicle in accordance with the final trajectory.

Abstract: A gas delivery system includes a 2-port valve including a first valve located between a first port and a second port. A 4-port valve includes a first node connected to a first port and a second port. A bypass path is located between the third port and the fourth port. A second node is located along the bypass path. A second valve is located between the first node and the second node. A manifold block defines gas flow channels configured to connect the first port of the 4-port valve to a first inlet, configured to connect the second port of the 4-port valve to the first port of the 2-port valve, the third port of the 4-port valve to a second inlet, the second port of the 2-port valve to a first outlet, and the fourth port of the 4-port valve to a second outlet.

Abstract: A separation device includes a membrane separation module (10), an adsorption module (20), and a gas intake module (30). The membrane separation module includes a first housing (110), and a membrane assembly (130) disposed in the first housing. The first housing has a first gas inlet (121), a first gas outlet (122), and a retentate gas outlet (123). The membrane module has a permeate gas outlet, the permeate gas outlet being in communication with the first gas outlet. The adsorption module has a second housing (210) and an adsorbent layer (230) disposed in it. The second housing is disposed on the first housing and has a second gas inlet (221), a second gas outlet (222), and a desorption gas outlet (223). The second gas inlet is in communication with the first gas outlet. The gas intake module has a third gas outlet (321) in communication with the first gas inlet.

Abstract: Systems and methods that include starch derived from grain as a carbon source for propagation of microorganisms.

Abstract: The present invention relates to an asphalt product. The asphalt product includes an asphalt binder and a bio-oil blend comprising a mixture of a non-hydrogenated bio-oil and a partially hydrogenated bio-oil, where the bio-oil blend is mixed with the asphalt binder to form an asphalt product having a shear stiffness of 0.20 kPa to 11,000 kPa at a temperature ranging from 25° C. to 85° C. and/or a viscosity of 0.15 Pa·s to 1.50 Pa·s at a temperature ranging from 120° C. to 165° C. The present invention further relates to methods of producing an asphalt product and methods of applying an asphalt product to a surface.

Abstract: There is provided an analog-stochastic converter for converting an analog voltage signal into a pulse signal having a corresponding probability. The analog-stochastic converter is implemented using a threshold switching element and a simple logic circuit, thereby reducing a size of the analog-stochastic converter and enabling a low power operation thereof. In addition, in order to update a weight, instead of an analog signal, a probability signal is applied using the above-described analog-stochastic converter, thereby updating a weight in a fully-parallel manner in a synaptic element array having an intersection structure. Accordingly, it is possible to shorten a time for weight update.

Abstract: Synthetic brochosomes can be prepared by disposing a monolayer of first polymer microspheres on a substrate and forming a layer of metal on the monolayer of the first polymer microspheres. A monolayer of second polymer microspheres is then disposed on the layer of metal to form a template. The second polymer microspheres are smaller than the first polymer microspheres. A brochosome material is then electrodeposited on the template. The brochosome material is selected from the group consisting of a metal, a metal oxide, a polymer or a hybrid thereof. The first polymer microspheres and the second polymer microspheres are then removed to form a coating of synthetic brochosomes of the brochosome material on the substrate.

Abstract: Specific binding members, particularly antibodies and fragments thereof, which bind to transforming growth factor beta 1 (TGF-?1) are provided, particularly recognizing human and mouse TGF-?1 and not recognizing or binding TGF-?2 or TGF-?3. Particular antibodies are provided which specifically recognize and neutralize TGF-?1. These antibodies are useful in the diagnosis and treatment of conditions associated with activated or elevated TGF-?1, including cancer, and for modulating immune cells and immune response, including immune response to cancer or cancer antigens. The anti-TGF-?1 antibodies, variable regions or CDR domain sequences thereof, and fragments thereof may also be used in therapy in combination with chemotherapeutics, immune modulators, or anti-cancer agents and/or with other antibodies or fragments thereof. Antibodies of this type are exemplified by the novel antibodies hereof, including antibody 13A1, whose sequences are provided herein.

Abstract: The present invention relates to a scanner having a flexible probe which is an apparatus capable of being utilized for an inspection on a weld zone of a general ferrite material and a stainless material and allowing an inspection to be performed on a fitting weld zone where it is difficult for a general phased array ultrasonic testing (PAUT) probe to approach.

Abstract: Provided are a circuit apparatus, a manufacturing method thereof, and a circuit system. The circuit apparatus includes a flexible circuit board, a flexible packaging material layer and an electronic device. The flexible circuit board has at least one hollow pattern, wherein the flexible circuit board has an inner region and a peripheral region surrounding the inner region, and has a first surface and a second surface opposite to each other. The flexible packaging material layer is disposed in the at least one hollow pattern. The electronic device is disposed on the first surface of the flexible circuit board and electrically connected with the flexible circuit board.

Abstract: Implementations described and claimed herein provide systems and methods for manufacturing customized cardiovascular devices. In one implementation, patient cardiovascular data for a patient is received at a controller. The patient cardiovascular data is captured using a patient interface. A printing profile for a cardiovascular medical device is received at the controller. A patient specific three-dimensional model of the cardiovascular medical device customized for the patient using the patient cardiovascular data and the printing profile is generated. The patient specific three-dimensional model of the cardiovascular medical device is sliced into a plurality of outlines using the controller. Print instructions based on the plurality of outlines are generated using the controller. A polymeric material is manipulated according to the print instructions into a customized polymeric cardiovascular medical device for the patient.

Abstract: A sensor for detecting properties of a gas, gas mixture, or a gas or gas mixture containing particles, all collectively referred to as a “gas”. A flow tube contains a pair of electrodes arranged such that at least a portion of the gas flows between the electrodes. A controller applies voltage to the electrodes and measures response data from the electrodes representing the voltage-current relationship between the electrodes while the gas is between the electrodes. Based on the response data, the controller determines a concentration of particles within the gas.

Abstract: Provided is a hydrogen isotope adsorbent with differential binding properties and including mesoporous silica doped with fluorine.

Abstract: A timepiece (100) including a case (10) including a middle (1), the top part whereof is closed by a bezel (2) and the bottom part whereof is closed by a back (3), a horological movement (4) mounted against the middle (1) by means of a casing ring (5), wherein the casing ring (5) comprises at least two clippable parts (50, 51) which hold the horological movement (4), the two parts being inseparable once mounted against the middle (1) when closing the case (10) of the timepiece (100).

Abstract: Methods and systems for imaging a target. In some examples, a system includes an optical modulator configured for applying, at each time of an exposure window, a respective optical modulation pattern to a received image of the target to output a modulated image. The system includes a camera configured for capturing a single image frame for the exposure window by receiving, at each of time, the modulated image of the target. The system includes a demodulator implemented on a computer system and configured for demodulating the single image frame based on the optical modulation patterns to recover a number of recovered image frames each depicting the target at a respective recovered time within the exposure window.

Abstract: The present invention relates to an encoding method and decoding method, and a device using the same. The encoding method according to the present invention comprises the steps of: specifying an intra prediction mode for a current block; and scanning a residual signal by intra prediction of the current block, wherein the step of scanning the residual signal can determine a scanning type for a luminance signal and a chroma signal of the current block according to an intra prediction mode for a luminance sample of the current block.

Abstract: Disclosed herein a disaggregation computing system. The disaggregation computing system comprising: a local computing device that comprises a local processor, a local memory bus, a local memory and a local disaggregation controller; a remote computing device that comprises a remote processor, a remote memory bus, a remote memory and a remote disaggregation controller; and a disaggregation network that connects the local computing device and the remote computing device, wherein the local disaggregation controller and the remote disaggregation controller are configured to: check a response delay for access of the remote memory, and control the access of the remote memory based on the response delay.

Abstract: A new and distinct cultivar of Centipedegrass named ‘Tift TC458’ is provided. The new and distinct variety has excellent turf quality, increased seed head production, and increased nematode resistance as compared to similar commercial centipedegrass. The sexually and asexually reproduced diploid variety is reliably propagated both vegetatively and by seed.