Patents Assigned to Research
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Patent number: 8958865Abstract: A lesion phantom is disclosed, which is a spherical ball having a cavity formed therein for housing contrast agents or medicines, and is enabled for the quantitative evaluation of a medical image in drug development and evaluation. In an embodiment, the cavity of the lesion phantom is coupled to a tapering ring and is configured to be sealed by a silicon plug, in order to ensure that contrast agents or medicines can be fed into the cavity easily and conveniently without causing any problem, such as overflowing, a bubble residue problem, radioactive contamination, etc. Moreover, by the arrangement of a retractable fixing bar, the positioning of the lesion phantom can be adjusted flexibly at will, and additionally by the tapering of the tapering ring, the lesion phantom can be prevented from being damaged by any extreme, sudden, unjust, or improper force exerted, and thus the lifespan of the lesion phantom can be prolonged.Type: GrantFiled: March 16, 2012Date of Patent: February 17, 2015Assignee: Institute of Nuclear Energy Research Atomic Energy Council, Executive YuanInventors: Shiang-Lin Hsu, Yu-Ching Ni, Meei-Ling Jan
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Patent number: 8957056Abstract: In one aspect, the present invention provides a method for treating colon and/or ovarian cancer in a subject comprising administering to a subject in need thereof a compound of general formula (I): wherein R1-R6, R, -R, Q, Y1, Y2 and n are as defined herein, wherein the compound is present in an amount effective to inhibit colon and/or ovarian tumor metastasis.Type: GrantFiled: May 25, 2005Date of Patent: February 17, 2015Assignee: Sloan-Kettering Instiute for Cancer ResearchInventors: Samuel J. Danishefsky, Christoph Gaul, Jón T. Njardarson, Malcolm A. S. Moore, Kaida Wu, David C. Dorn, Mihirbaran Mandal
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Patent number: 8956669Abstract: The present disclosure describes the isolation of extremophilic microorganisms from the Lakes of Schirmacher Oasis located in the East Antarctic Dronning Maud Land. The isolated organisms were characterized and certain pigments produced by these microorganisms were isolated. The present disclosure teaches that the isolated pigments exhibit anticancer and antimicrobial properties and can be used as new therapies for the treatment and prevention of cancer and microbially-mediated diseases.Type: GrantFiled: February 19, 2010Date of Patent: February 17, 2015Assignee: The UAB Research FoundationInventor: Asim Bej
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Patent number: 8957273Abstract: The present invention relates to a process to make light olefins, in a combined XTO-OC process, from an oxygen-containing, halogenide-containing or sulphur-containing organic feedstock comprising: a0) providing a first portion and a second portion of said oxygen-containing, halogenide-containing or sulphur-containing organic feedstock, a) providing a catalyst comprising zeolitic molecular sieves containing at least 10 membered ring pore openings or larger in their microporous structure, b) providing an XTO reaction zone, an OC reaction zone and a catalyst regeneration zone, said catalyst circulating in the three zones, such that at least a portion of the regenerated catalyst is passed to the OC reaction zone, optionally at least a portion of the catalyst in the OC reaction zone is passed to the XTO reaction zone and at least a portion of the catalyst in the XTO reaction zone is passed to the regeneration zone; c) contacting the first portion of said oxygen-containing, halogenide-containing or sulphur-containType: GrantFiled: June 24, 2009Date of Patent: February 17, 2015Assignee: Total Research & Technology FeluyInventors: Nikolai Nesterenko, Walter Vermeiren, Giacomo Grasso, Sander Van Donk, Wolfgang Garcia
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Patent number: 8958511Abstract: A system and method for detecting broadband global positioning system (GPS) jamming is provided, the system including a local oscillator maintainer to maintain a plurality of local oscillators, a frequency band selector to select a frequency band in which jamming is to be detected, in response to receipt of a radio frequency (RF) signal, an oscillating signal output unit to allow an oscillating signal to be output from a local oscillator identified based on the selected frequency band, among the plurality of local oscillators, and an intermediate frequency (IF) signal generator to generate an IF signal using the RF signal and the oscillating signal.Type: GrantFiled: September 11, 2013Date of Patent: February 17, 2015Assignee: Electronics and Telecommunications Research InstituteInventors: In One Joo, Jeom Hun Lee, Cheon Sig Sin, Sang Uk Lee
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Patent number: 8957202Abstract: An enterosoluble and intestinal-enzyme-biodegradable material is provided. The enterosoluble and intestinal-enzyme-biodegradable material includes a modified amylopectin, wherein at least one of hydrogen atoms is replaced by —CO—(CH2)n—COOH (n is 2-4) and the modified amylopectin has an acid value of 35-180 mg KOH/g. The disclosure also provides a method for preparing an enterosoluble and intestinal-enzyme-biodegradable material.Type: GrantFiled: April 2, 2012Date of Patent: February 17, 2015Assignee: Industrial Technology Research InstituteInventors: Chien-Pang Wu, Jyh-Horng Wu, Su-Jane Lo
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Patent number: 8957387Abstract: Some embodiments relate to an absorption probe for measuring an amount of dissolved organic carbon in an aqueous sample, the absorption probe comprising: a housing defining an analysis zone for the containment or passage of an aqueous sample; a light reflector disposed within said housing; an ultraviolet light emitting device disposed within said housing and operable to radiate ultraviolet light along an optical path that passes through the aqueous sample to impinge on said reflector; and a light detector disposed within said housing and operable to detect radiated light reflected from said reflector and to output a received signal from said detected reflected light, said received signal indicative of a measure of an amount of dissolved organic carbon in the aqueous sample.Type: GrantFiled: June 23, 2011Date of Patent: February 17, 2015Assignee: Commonwealth Scientific and Industrial Research OrganisationInventors: Brett Alexander Sexton, Michael John Best
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Patent number: 8957030Abstract: The invention provides a method of reducing or preventing mitochondrial permeability transitioning. The method comprises administering an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about twenty amino acids; a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3pm is the largest number that is less than or equal to r+1; and a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 2 a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1.Type: GrantFiled: February 27, 2013Date of Patent: February 17, 2015Assignees: Cornell Research Foundation, Inc., Institute de Recherches Cliniques de MontrealInventors: Hazel H. Szeto, Peter W. Schiller, Kesheng Zhao
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Patent number: 8957732Abstract: An amplifier and a transceiver including the amplifier are provided. The amplifier includes an input terminal; a first transistor of a first conductivity and a second transistor of a second conductivity, each transistor comprising a source terminal, a gate terminal and a drain terminal respectively, the source terminal of the first transistor being coupled to the source terminal of the second transistor, and the gate terminal of the first transistor and the gate terminal of the second transistor being coupled to the input terminal; and an output terminal coupled to the drain terminal of the first transistor and the drain terminal of the second transistor.Type: GrantFiled: May 25, 2011Date of Patent: February 17, 2015Assignee: Agency for Science, Technology and ResearchInventors: Hyouk Kyu Cha, Yuan Gao, Xiaojun Yuan
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Patent number: 8957112Abstract: The invention relates to a composition in the form of a cream gel comprising, in a physiologically acceptable medium, at least one dispersed retinoid and dispersed benzoyl peroxide, to its process of preparation and to its use in cosmetics and in dermatology.Type: GrantFiled: June 22, 2009Date of Patent: February 17, 2015Assignee: Galderma Research & DevelopmentInventors: Claire Mallard, Fabienne Louis, Emmanuelle At
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Patent number: 8957266Abstract: Provided are processes for making one or more unsaturated oligomeric acids and one or more saturated hydrocarbons. In one form, a process for making one or more saturated hydrocarbons includes oligomerizing one or more unsaturated carboxylic acids having from 4 to 38 carbon atoms in the presence of a molecular sieve catalyst to form one or more unsaturated oligomeric acids including less than 90% by weight of cyclic oligomers, and hydrogenating the one or more unsaturated oligomeric acids via contact with hydrogen in the presence of a hydrogenation catalyst to form one or more saturated hydrocarbons. The oligomerizing of unsaturated fatty acids is from renewable biological sources to form dimer acids. The one or more saturated hydrocarbons are useful as lubricant base oils.Type: GrantFiled: March 4, 2010Date of Patent: February 17, 2015Assignee: ExxonMobil Research and Engineering CompanyInventors: Kun Wang, Margaret May-Som Wu, David Lawrence Stern
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Patent number: 8956867Abstract: A three-dimensional microwell system that supports long term pluripotent cell culture and formation of homogeneous embryoid bodies (EBs) is described. Microwell-cultured pluripotent cells remain viable and undifferentiated for several weeks in culture and maintain undifferentiated replication when passaged to Matrigel®-coated, tissue culture-treated polystyrene dishes. Microwell-cultured pluripotent cells maintain pluripotency, differentiating to each of the three embryonic germ layers. Pluripotent cell aggregates released from microwells can be passaged for undifferentiated replication or differentiated to monodisperse EBs. The ability to constrain pluripotent cell growth in three dimensions advantageously provides for more efficient, reproducible culture of undifferentiated cells, high-throughput screening, and the ability to direct pluripotent cell differentiation by generating monodisperse EBs of a desired size and shape.Type: GrantFiled: November 9, 2009Date of Patent: February 17, 2015Assignee: Wisconsin Alumni Research FoundationInventors: Timothy J. Kamp, Jianhua Zhang, Jeffrey C. Mohr, Juan J. Depablo, Sean P. Palecek
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Publication number: 20150043079Abstract: An active diffuser for reducing a speckle in accordance with an embodiment of the present invention includes: an electroactive polymer film having at least one or more scattering patterns; a first transparent electrode coated on one surface of the electroactive polymer film; and a second transparent electrode coated on the other surface of the electroactive polymer film, and a shape of the scattering pattern of the electroactive polymer film is varied by voltage applied through the first transparent electrode and the second transparent electrode.Type: ApplicationFiled: January 30, 2014Publication date: February 12, 2015Applicant: Electronics and Telecommunications Research InstituteInventors: Sun-Tak PARK, Bong-Je PARK, Ki-Uk KYUNG, Sung-Ryul YUN, Sae-Kwang NAM
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Publication number: 20150041312Abstract: Provided is a Li-containing phosphoric-acid compound sintered body of both high relative density and very small crystal grain diameter with reduced incidence of defects (voids) such as air holes, the Li-containing phosphoric-acid compound sintered body causing a Li-containing phosphoric-acid compound thin film useful as a solid electrolyte for a secondary cell or the like to be stabilized without any incidence of target cracking or irregular electrical discharge, and offering high-speed film-forming capability. This Li-containing phosphoric-acid compound sintered body contains no defects measuring 50 ?m or larger within a 1 mm2 cross-sectional region in the interior thereof, while having an average crystal grain diameter of no more than 15 ?m and a relative density of at least 85%.Type: ApplicationFiled: April 10, 2013Publication date: February 12, 2015Applicant: KOBELCO RESEARCH INSTITUTE, INC.Inventors: Yuichi Taketomi, Yuki Tao, Moriyoshi Kanamaru
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Publication number: 20150045244Abstract: The object of the invention is to find a simple biomarker with high reproducibility with regard to a method for evaluating the activity of the condition and progression of rheumatoid arthritis disease and provide an effective evaluation method therefor. The invention is to provide a method for determining the value of a rheumatoid arthritis-linked indicator in a subject, the method being characterized by comprising a step for measuring the amount of expression of the FAM20A gene in blood collected from the subject, a step for analyzing the measured amount of expression using a gene expression profile that is prepared in advance and correlates with the indicator and a step for estimating the value of the indicator in the subject on the basis of the analysis results.Type: ApplicationFiled: November 17, 2011Publication date: February 12, 2015Applicants: DNA CHIP RESEARCH INC., SAITAMA MEDICAL UNIVERSITY, KEIO UNIVERSITYInventors: Tsutomu Takeuchi, Koichi Amano, Yohei Ishizawa, Seiji Nakamura, Motohiko Tanino, Yuko Hata
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Publication number: 20150044873Abstract: A method of forming a silicon containing confinement ring for a plasma processing apparatus useful for processing a semiconductor substrate comprises inserting silicon containing vanes into grooves formed in a grooved surface of an annular carbon template wherein the grooved surface of the annular carbon template includes an upwardly projecting step at an inner perimeter thereof wherein each groove extends from the inner perimeter to an outer perimeter of the grooved surface. The step of the grooved surface and a projection at an end of each silicon containing vane is surrounded with an annular carbon member wherein the annular carbon member covers an upper surface of each silicon containing vane in each respective groove. Silicon containing material is deposited on the annular carbon template, the annular carbon member, and exposed portions of each silicon containing vane thereby forming a silicon containing shell of a predetermined thickness.Type: ApplicationFiled: August 7, 2013Publication date: February 12, 2015Applicant: Lam Research CorporationInventor: Michael C. Kellogg
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Publication number: 20150044257Abstract: An optimized baculovirus/insect cell-mediated system is provided for the production of enterovirus 71 virus-like particles to produce a vaccine against recent EV71 virus outbreaks. Co-expression of the viral capsid polyprotein P1 ORF derived from a fatal case in the Fuyang province of the People's Republic of China plus the 3 CD protease of EV71 prototype strain BrCr resulted in the formation of VLPs. The yields were increased by co-expression of both P1 and 3CD in separate transgene cassettes arranged in opposite orientation in a bicistronic baculovirus vector and by inserting the translational enhancing signal L21 in front of the capsid protein open reading frame. Faster transgene processing was achieved by using insect Sf21 cells instead of Sf9 cells.Type: ApplicationFiled: March 22, 2013Publication date: February 12, 2015Applicant: Fred Hutchinson Cancer Research CenterInventors: Denise A. Galloway, Joerg Enssle
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Publication number: 20150042430Abstract: A system and method for tailoring a polarity transition of a magnetic structure is provided that involves printing one or more reinforcing maxels alongside one side or both sides of a polarity transition boundary between a first polarity region of the magnetic structure having a first polarity and a second polarity region of the magnetic structure having a second polarity, where printing reinforcing maxels alongside the polarity transition boundary improves the magnetic field characteristics of the polarity transition.Type: ApplicationFiled: August 18, 2014Publication date: February 12, 2015Applicant: CORRELATED MAGNETICS RESEARCH, LLCInventors: Larry W. Fullerton, Jacob S. Zimmerman, Robert S. Evans, David P. Machado, Jason N. Morgan, Mark D. Roberts
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Publication number: 20150046060Abstract: Settings in a vehicle are adjusted by first learning a predictive model of output vectors that correspond to input vectors of sensor data acquired from vehicle subsystems during training. Each input vector defines a known context associated with the vehicle. During later operation of the vehicle, additional input vectors are obtained from the subsystems, and the corresponding output vectors to adjust the settings are then determined using the predictive model.Type: ApplicationFiled: August 12, 2013Publication date: February 12, 2015Applicant: Mitsubishi Electric Research Laboratories, Inc.Inventors: Daniel Nikolaev Nikovski, Michael Jones
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Publication number: 20150041366Abstract: This disclosures provides an adsorbent which, on the basis of the total weight of the adsorbent, comprises: 1) a Si—Al molecular sieve having an A-FAU structure, wherein A represents a monovalent cation, in an amount of 1-20 wt %, 2) at least one binder selected from the group consisting of titanium dioxide, stannic oxide, zirconium oxide and alumina, in an amount of 3-35 wt %, 3) a silica source, in an amount of 5-40 wt %, 4) zinc oxide, in an amount of 10-80 wt %, and 5) at least one promoter metal selected from the group consisting of cobalt, nickel, iron and manganese, based on the metal, in an amount of 5-30 wt %, wherein at least 10 wt % of the promoter metal is present in a reduced valence state. This adsorbent exhibits improved activity and stability, and at the same time, is capable of significantly improving the octane number of the product gasoline.Type: ApplicationFiled: July 27, 2012Publication date: February 12, 2015Applicants: RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC, CHINA PETROLEUM & CHEMICAL CORPORATIONInventors: Wei Lin, Huiping Tian, Zhenbo Wang