Patents Assigned to Research
  • Patent number: 8956862
    Abstract: The present invention discloses a method of isolation, pooling and further culturing of Mesenchymal Stem cells (MSC) for clinical application. Present invention also discloses the method of establishing Master Cell bank, followed by Working Cell Bank from which the final therapeutic composition referred to as Investigational Product/Investigational Medicinal Product comprising of allogenic bone marrow-derived MSC is formulated for clinical applications.
    Type: Grant
    Filed: November 25, 2010
    Date of Patent: February 17, 2015
    Assignee: Stempeutics Research Pvt. Ltd.
    Inventors: Rakhi Pal, Pawan Kumar Gupta, Prasanna Kumar Kemburu, Jyothi Prasanna, Satish Totey, Raviraja Neelavar Seetharam, Umesh Baikunje Golithadka, Anish Sen Majumdar
  • Patent number: 8956698
    Abstract: Systems and methods for depositing complex thin-film alloys on substrates are provided. In particular, systems and methods for the deposition of thin-film Cd1-xMxTe ternary alloys on substrates using a stacked-source sublimation system are provided, where M is a metal such as Mg, Zn, Mn, and Cu.
    Type: Grant
    Filed: April 7, 2014
    Date of Patent: February 17, 2015
    Assignee: Colorado State University Research Foundation
    Inventors: Walajabad S. Sampath, Pavel S. Kobyakov, Kevin E. Walters, Davis R. Hemenway
  • Patent number: 8958939
    Abstract: The present invention presents a method and system for an autonomous mower attached with a camera, wherein the control of the parameters of the camera and the control of the mower movement and grass detection are optimized holistically during operation. The present invention mitigates the camera sensing limits by adapting the movement speed of the mower. Furthermore, the camera control optimizes the visibility of grass by using the grass mask of a grass segmentation to calculate updated exposure, gain and aperture values only from grass pixels. The grass segmentation tracks changes in the grass color that are caused by illumination differences. Optionally, the system is equipped with a head light used to further improve the camera signal quality in conjunction with the control of the camera parameters and the movement speed of the mower.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: February 17, 2015
    Assignee: Honda Research Institute Europe GmbH
    Inventors: Nils Einecke, Mathias Franzius
  • Patent number: 8957093
    Abstract: The invention provides molecular entities that bind with high affinity to PPARG (PPAR?), inhibit kinase-mediated, e.g., cdk5-mediated, phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes, insulin resistance, impaired glucose tolerance, pre-diabetes, hyperglycemia, hyperinsulinemia, obesity, or inflammation. In methods of treatment of these conditions using a compound of the invention, the compound can avoid producing side effects of significant weight gain, edema, impairment of bone growth or formation, or cardiac hypertrophy, or any combination thereof, in the patient receiving the compound. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided.
    Type: Grant
    Filed: June 6, 2012
    Date of Patent: February 17, 2015
    Assignee: The Scripps Research Institute
    Inventors: Theodore Mark Kamenecka, Patrick R. Griffin, Marcel Koenig, Alice Asteian, Anne-Laure Blayo, Yuanjun He, Youseung Shin
  • Patent number: 8957057
    Abstract: The present invention concerns the uses of an azaphilone compound of formula (I): formula (I): or a pharmaceutically acceptable derivative thereof as described in the specification for modulation of the activity of a nuclear hormone receptor and for prevention and/or treatment of a disease or disorder related to nuclear hormone receptor activity.
    Type: Grant
    Filed: April 5, 2010
    Date of Patent: February 17, 2015
    Assignee: Food Industry Research and Development Institute
    Inventors: Ta-Wei D. Liu, Yen-Lin Chen, Ming-Der Wu, Ming-Jen Cheng, Hui-Ping Chen, Wen-Jung Wu, Kai-Ping Chen, Yu-Shan Lin, Gwo-Fang Yuan
  • Patent number: 8956134
    Abstract: A fixed vane positive displacement rotary device is disclosed that includes a primary rotor and one or more scavenging rotors rotatably disposed in a rotor encasement. The primary rotor includes a plurality of protrusions. And each of the scavenging rotors includes a first curved surface that is configured to move adjacent to the primary rotor between the protrusions as the primary rotor and scavenging rotors rotate, a protrusion-receiving groove extending that is configured to receive one of the plurality of protrusions therein so that at least a tip of that protrusion moves adjacent to the protrusion-receiving groove as the primary rotor and scavenging rotors rotate, and a second curved surface and a third curved surface extending away from a center of the protrusion-receiving groove on opposing sides of the protrusion-receiving groove that are configured to move adjacent to a leading side and a trailing side of the one protrusion, respectively.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: February 17, 2015
    Assignee: Mallen Research Limited
    Inventors: David Alton McDaniel, Jr., Thomas Towles Lawson, Jr., James W. Newman, Jr.
  • Patent number: 8957035
    Abstract: Provided are methods and compositions for the treatment or prevention of ocular angiogenesis and neovascularization. Administration of stimulators of the TLR3 and TLR7 receptors, Trif or of IL-10 and IL-12 inhibits ocular angiogenesis. Furthermore, all siRNAs (both targeted and non-targeted) can inhibit ocular angiogenesis.
    Type: Grant
    Filed: May 15, 2007
    Date of Patent: February 17, 2015
    Assignee: University of Kentucky Research Foundation
    Inventor: Jayakrishna Ambati
  • Patent number: 8956208
    Abstract: A system for removing plant material from harvested crops includes a pinch roller conveyor including pairs of rotatable pinch rollers whose longitudinal axes are aligned with a length of the conveyor, the pinch rollers forming nips in which plant material can be caught and pulled down through the conveyor as the pinch rollers rotate, wherein first ends of the pinch rollers are laterally displaceable so that the pinch rollers can laterally separate from each other to facilitate passage of plant material.
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: February 17, 2015
    Assignee: University of Florida Research Foundation
    Inventors: Reza J. Ehsani, Amanda Lynn Valentine, Won Suk Lee
  • Patent number: 8956461
    Abstract: An apparatus used for rapid removal of polymer films from plasma confinement rings while minimizing erosion of other plasma etch chamber components is disclosed. The apparatus includes a center assembly, an electrode plate, a confinement ring stack, a first plasma source, and a second plasma source. The electrode plate is affixed to a surface of the center assembly with a channel defined along the external circumference therein. A first plasma source is disposed within the channel and along the external circumference of the center assembly, wherein the first plasma source is configured to direct a plasma to the inner circumferential surface of the confinement ring stack. A second plasma source located away from the first plasma source is configured to perform processing operations on a substrate within the etch chamber.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: February 17, 2015
    Assignee: Lam Research Corporation
    Inventors: Eric Hudson, Andreas Fischer
  • Patent number: 8958868
    Abstract: A system for transmitting bioelectrical signals. The system includes an implantable bioelectrical sensor for receiving at least one bioelectrical signal; an analog-to-time converter for converting the received bioelectrical signal from an analog domain to a time domain signal; and a radio frequency (RF) modulator for transmitting the time domain signal. The the analog-to-time converter and the RF modulator are implantable in a living being.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: February 17, 2015
    Assignees: Georgia Tech Research Corporation, North Carolina University
    Inventors: Maysam Ghovanloo, Ming Yin
  • Patent number: 8957460
    Abstract: The invention provides a semiconductor device for the detection of an active site-containing protein or a ligand thereof in a solution, said device comprising at least one insulating or semi-insulating layer; at least one conducting semiconductor layer, two conducting pads on top of the upper layer making electrical contact with said at least one conducting semiconductor layer, such that electrical current can flow between them at a finite distance from the surface of the device; a protective molecular layer fabricated on top of said upper layer and protecting said layer from corrosion; and said ligand or active site-containing protein linked to said protective molecular layer. Exposure of said ligand or active site-containing protein to a solution containing said active site-containing protein or ligand, respectively, causes a current change through the device when a constant electric potential is applied between the two conducting pads.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: February 17, 2015
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Ron Naaman, Eyal Capua, Danny Bavli, Maria Tkachev
  • Patent number: 8955529
    Abstract: In a spin-chuck with plural collector levels, a separate exhaust controller is provided for each level. This permits selectively varying gas flow conditions among the collector levels, so that the ambient pressure at one level does not adversely affect device performance in an adjacent level.
    Type: Grant
    Filed: January 4, 2010
    Date of Patent: February 17, 2015
    Assignee: Lam Research AG
    Inventor: Karl-Heinz Hohenwarter
  • Patent number: 8956871
    Abstract: The disclosure provides a cell culture system and a serum-free method for cultivating cells. The cell culture system includes a substratum, wherein the substratum has a surface. A polymer is disposed on the surface of the substratum, wherein the polymer is prepared by polymerizing a first monomer with a second monomer. The first monomer has a structure as represented by Formula (I), and the second monomer has a structure as represented by Formula (II): wherein, R1 is hydrogen or methyl; R2 is methyl, ethyl, or —CH2CH2OCH3; R3 is hydrogen or methyl; and, R4 is hydrogen, —CH2CH2OCOCHCHCOOH, —CH2CH2OCOCH2CH2COOH, or —CH2CH2COOH.
    Type: Grant
    Filed: December 13, 2012
    Date of Patent: February 17, 2015
    Assignee: Industrial Technology Research Institute
    Inventors: Pei-Ju Lin, Guilhem Tourniaire, Yi-Chen Chen, Kathryn Swindells, Bin-Ru She, Hsiang-Chun Hsu, Chih-Ching Liao, Su-Yo Lin
  • Patent number: 8958296
    Abstract: An access point (AP) measures a congestion level of a transmission channel representing a collision probability between frames at a channel busy duration and transmits the congestion level to a terminal. Therefore, the terminal extracts a congestion level that is included in a frame that is received from the AP through a scan process for searching for an AP to which the terminal is to connect. The terminal selects an AP to connect from at least one AP based on the extracted congestion level of the transmission channel.
    Type: Grant
    Filed: May 20, 2011
    Date of Patent: February 17, 2015
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Ki Jong Koo, Do Young Kim, Byung Sun Lee
  • Patent number: 8959015
    Abstract: Provided is an apparatus for integrally encoding and decoding a speech signal and an audio signal. An encoding apparatus for integrally encoding a speech signal and an audio signal, may include: a module selection unit to analyze a characteristic of an input signal and to select a first encoding module for encoding a first frame of the input signal; a speech encoding unit to encode the input signal according to a selection of the module selection unit and to generate a speech bitstream; an audio encoding unit to encode the input signal according to the selection of the module selection unit and to generate an audio bitstream; and a bitstream generation unit to generate an output bitstream from the speech encoding unit or the audio encoding unit according to the selection of the module selection unit.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: February 17, 2015
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Tae Jin Lee, Seung Kwon Beack, Minje Kim, Dae Young Jang, Kyeongok Kang, Jin Woo Hong, Hochong Park, Young-Cheol Park
  • Patent number: 8957813
    Abstract: A case for a wireless tablet computer device includes a number of RF resonant loop elements and elongated RF director coupling strip elements mounted in the case and configured such that RF radiation is coupled from an internal antenna of the wireless device out of the device to the RF resonant and coupling elements. The case incorporates a cut-out section in a location leaving exposed a strip that covers an area proximate the internal antenna. The RF resonant loops and director coupling strip elements alternatively may be incorporated with the wireless tablet computer device itself.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: February 17, 2015
    Assignee: Pong Research Corporation
    Inventors: Ryan G McCaughey, Karl Richard Shields, Nikhil Nilakantan
  • Patent number: 8956836
    Abstract: The present invention provides a simpler and more energy efficient process for the preparation of fatty acid methyl ester (biodiesel) from sun dried whole seed capsules of Jatropha curcas integrated with value addition of seed shells, deoiled cake and crude glycerol co-product stream. More specifically, the invention relates to a method of dispensing with the need for excess methanol recovery through distillation, cost-effective resin treatment for the refining of methyl ester and utilization of co-streams for preparation of high density energy briquettes and Polyhydroxyalkanoate biodegradable polymer in efficient and cost-effective manner.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: February 17, 2015
    Assignee: Council of Scientific and Industrial Research
    Inventors: Pushpito Kumar Ghosh, Sandhya Chandrika Prasad Mishra, Mahesh Ramniklal Gandhi, Sumesh Chandra Upadhyay, Parimal Paul, Pritpal Singh Anand, Kiritkumar Mangaldas Popat, Anupama Vijaykumar Shrivastav, Sanjiv Kumar Mishra, Neelam Ondhiya, Ramesh Dudabhai Maru, Gangadharan Dyal, Harshad Brahmbhatt, Vinod Boricha, Doongar Ram Chaudhary, Babulal Rebary, Krushnadevsingh Sukhdevsinh Zala
  • Patent number: 8958288
    Abstract: Provided is a method and apparatus for setting a detour path in a wideband high frequency wireless system using a centralized Media Access Control (MAC) protocol. Here, in a wireless system using the centralized MAC protocol where a time synchronization and a band allocation may be performed by a single central control unit, when a signal blockage occurs while a data communication is being performed via a direct path between a source device and a destination device, the detour path may be quickly provided.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: February 17, 2015
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Seung Eun Hong, Kyeongpyo Kim, Yong Sun Kim, Hyoung Jin Kwon, Woo Yong Lee
  • Patent number: 8956712
    Abstract: A power source for a solid state device includes: a first frame having a first contact portion, a first bonding portion and a first extension portion between the first contact portion and the first bonding portion; a second frame having a second contact portion, a second bonding portion and a second extension portion between the second contact portion and the second bonding portion; and a first pole layer, an electrolyte layer and a second pole layer positioned between the first and second contact portions, wherein a first portion of the electrolyte layer is positioned between the first extension and the first pole and a second portion of the electrolyte layer is positioned between the first extension and the second pole.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: February 17, 2015
    Assignees: Medtronic, Inc., Sapurast Research LLC
    Inventors: Michael W. Barror, John K. Day, Shawn W. Snyder, Alexandra Z. LaGuardia, Damon E. Lytle, Bernd J. Neudecker
  • Patent number: 8958498
    Abstract: Provided is a method of generating a driving signal for driving a dual mode supply modulator for a power amplifier. The method includes obtaining an envelope of a complex baseband signal to be transmitted, comparing the envelope of the complex signal with a preset threshold value, when a current envelope of the complex signal is the preset threshold value or greater or when there is a result having the preset threshold value or greater in previous N comparisons, outputting a digital board output signal configured with a first logic level through a digital-to-analog converter; and when the current envelope of the complex signal is smaller than the preset threshold value and when there is no result having the preset threshold value or greater in the previous N comparisons, outputting a digital board output signal configured with a second logic level through the digital-to-analog converter.
    Type: Grant
    Filed: May 1, 2014
    Date of Patent: February 17, 2015
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Sung Jun Lee, Jae Ho Jung, Kwangchun Lee