Patents Assigned to Research
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Publication number: 20240016638Abstract: A gastric bypass device includes an occlusion device that is adapted to be deployed relative to a patient's pyloric sphincter, an anastomosis anchor that is adapted to be deployed relative to an anastomosis between the patient's stomach and their small intestine, and a tether that extends through the patient's small intestine between the occlusion device and the anastomosis anchor. A dynamic leash may be secured relative to the occlusion device and may work in conjunction with the tether to help hold the occlusion device in place.Type: ApplicationFiled: July 18, 2023Publication date: January 18, 2024Applicants: Boston Scientific Scimed, Inc., Mayo Foundation for Medical Education and ResearchInventors: Roger W. McGowan, Jessica Brand, Daniel Lee Krautkremer, Alexander James Wiedmann, Barham K. Abu Dayyeh, Benjamin Moses Cooke, Burton Hedstrom, Leo Joseph Steiner
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Publication number: 20240018712Abstract: A clothes treating apparatus includes: a cabinet; a tub positioned inside the cabinet; a drum configured to rotate inside the tub; and a damper coupled to the cabinet and the tub and configured to reduce vibrations of the tub according to a rotation of the drum. The damper includes: a piston; a cylinder forming an inside space in which the piston is movable, the cylinder including a yoke and a bobbin positioned at one side of the yoke; and a friction member positioned between an outer surface of the piston and an inner surface of the cylinder and including a magneto-rheological fluid of which viscosity changes according to a magnetic field. A thickness of the friction member positioned between the piston and the bobbin is smaller than a thickness of the friction member positioned between the piston and the yoke.Type: ApplicationFiled: June 14, 2023Publication date: January 18, 2024Applicants: SAMSUNG ELECTRONICS CO., LTD., Inha University Research and Business FoundationInventors: Doyeon KIM, Seungbok CHOI, Hyungjin CHOE, Byunghyuk KANG, Jeonghoon KANG, Bogyu KIM, Yujin PARK, Jaeik PARK, Junhyeong PARK, Sejun LEE
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Publication number: 20240018257Abstract: The present invention provides monoclonal antibodies that recognize poliovirus receptor (PVR) and inhibit its binding to T cell immunoreceptor with Ig and ITIM domains (TIGIT). The present invention further provides pharmaceutical compositions comprising the antibodies and methods for their use in cancer immunotherapy, treating infections and in diagnosis.Type: ApplicationFiled: August 15, 2023Publication date: January 18, 2024Applicants: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., UNIVERSITY OF RIJEKA FACULTY OF MEDICINEInventors: Ofer MANDELBOIM, Noa S. KAYNAN, Pinchas TSUKERMAN, Stipan JONJIC
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Publication number: 20240022000Abstract: Disclosed is a terahertz band beamforming antenna system. A terahertz band beamforming antenna system includes: a metal waveguide top portion; and a metal waveguide bottom portion which is coupled to the metal waveguide top portion, and at which an antenna portion including a feed transmission line and a radiation antenna is positioned, wherein the metal waveguide top portion and the metal waveguide bottom portion may have radiation openings, and may be coupled to seal at least a top surface, a bottom surface, and both side surfaces of the antenna portion.Type: ApplicationFiled: July 18, 2023Publication date: January 18, 2024Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATIONInventors: Moon Il KIM, Yang Woo KIM, Yun Kyeong KOH
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Publication number: 20240018221Abstract: The invention relates generally to antigen-binding molecules that specifically bind to Myosin Heavy Chain 9 (MYH9) and uses thereof for the treatment of specific cancers, such as mast cell tumors. In one embodiment, the MYH9 is canine MYH9 and the antigen-binding molecule is an antibody. In another embodiment, the antigen-binding molecule is conjugated to a toxin, for the treatment of canine mast cell tumors.Type: ApplicationFiled: October 26, 2021Publication date: January 18, 2024Applicant: Agency for Science, Technology and ResearchInventors: Wey Jia FONG, Boon Hwa CHOO, Mei Yee Vanessa DING, Chui Ping CHIN
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Publication number: 20240018592Abstract: A method of analyzing the therapeutic efficacy of a therapeutic agent for treating an immune-related disorder is disclosed. The method comprises contacting blood cells of the subject with the agent, measuring the expression of at least 20 genes in the blood cells of the subject; obtaining an immune age value based on the expression of the at least 20 genes, and comparing the immune age value with an immune age value of the subject calculated on the basis of expression of the at least 20 genes in blood cells of the subject, in the absence of the agent.Type: ApplicationFiled: October 26, 2021Publication date: January 18, 2024Applicants: Technion Research & Development Foundation Limited, Rambam Med-Tech Ltd.Inventors: Shai S. SHEN-ORR, Yehuda CHOWERS, Ayelet ALPERT, Shiran GERASSY-VAINBERG, Erik FELDMAN
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Publication number: 20240018550Abstract: Proposed are an adenine base editor having increased thymine-cytosine sequence-specific cytosine base editing activity, a cytosine base editing method, and a cytosine base editing kit. The editor, produced by introducing a P48R mutation into an adenosine deaminase, has an operating range that is more sophisticated than conventional cytosine base editors, allows cytosine base editing only when cytosine is positioned right behind thymine, thereby enabling elaborate editing even when there is a plurality of cytosines within the range, and enables cytosine to be substituted with thymine or guanine in the presence or absence of UGI, respectively. Therefore, the cytosine base editing composition can be effectively used in the fields of gene therapy or new crop development which requires precise editing of only cytosine in all living organisms, including humans, plants, and bacteria.Type: ApplicationFiled: December 1, 2021Publication date: January 18, 2024Applicants: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY), Korea University Research and Business FoundationInventors: Sangsu BAE, You Kyeong JEONG, Seokhoon LEE, Jae-Sung WOO
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Publication number: 20240016198Abstract: A water-based electronic cigarette liquid is disclosed. The water-based electronic cigarette liquid includes the following ingredients in parts by mass: 5-60 parts of water, 5-50 parts of smoke ingredient which is solid at normal temperature and is soluble in water, and 0-30 parts of glycerol. The electronic cigarette liquid in this invention has environmental protection, high safety, comfortable smoking taste, high smoke producing effect, and low viscosity.Type: ApplicationFiled: January 20, 2020Publication date: January 18, 2024Applicants: CHINA TOBACCO HUNAN INDUSTRIAL CO., LTD., SHANGHAI NEW TOBACCO PRODUCT RESEARCH INSTITUTE CO., LTD., CHINA TOBACCO HENAN INDUSTRIAL CO., LTD.Inventors: Jianfu Liu, Jianhua Yi, Wen Du, Jiaruo Huang, Zhiguo Wang, Xinliang Tan, Kejun Zhong, Zhiwei Sun, Wei Liu, Jingbo Chen, Chao Tan, Chao Chen, Chaoying Chen, Jing Yang, Qishan Yuan, Xinqiang Yin, Xiaoyi Guo, Jianxin Ren
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Publication number: 20240016503Abstract: The endplate perforator includes a pipe, an operation portion disposed at a rear end of the pipe, a case that is disposed at a front end of the pipe and includes an insertion surface configured to be placed parallel to an endplate of a vertebra, a needle member housed in the case and configured to perforate the endplate of the vertebra, and a mechanism portion configured move the needle member in a direction perpendicular to the insertion surface in response to an operation of the operation portion to cause the needle member to project or retract relative to the case.Type: ApplicationFiled: September 22, 2021Publication date: January 18, 2024Applicant: NATIONAL UNIVERSITY CORPORATION TOKAI NATIONAL HIGHER EDUCATION AND RESEARCH SYSTEMInventor: Satoshi NOZAWA
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Patent number: 11876865Abstract: The present disclosure relates to a method of and an apparatus for generating a space for sharing augmented reality content among multiple participants. With the method and the apparatus, an object for configuring a virtual space, which is proposed in an actual space, can also be proposed, in a spatial matching manner on a per-user basis, inside a common sharing space in augmented reality content by utilizing the technology of generating a space for sharing augmented reality content among multiple participants.Type: GrantFiled: September 27, 2022Date of Patent: January 16, 2024Assignee: Electronics and Telecommunications Research InstituteInventors: Beom Ryeol Lee, Jeung Chul Park, Wook Ho Son, Yong Ho Lee
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Patent number: 11876188Abstract: The present disclosure relates to an electrolyte comprising: a) a sodium salt; b) an additive comprising at least one additional metallic/metalloid cation having a standard reduction potential which is at least 2.5V more positive than that of sodium cation; wherein said sodium salt and said additive are dispersed in a solvent comprising at least one alkyl carbonate, and wherein the concentration of said metallic/metalloid cation in the electrolyte is 15 mM to 250 mM. The present disclosure also relates to a sodium-sulfur cell comprising a sodium anode, a microporous sulfur cathode, and the electrolyte as described herein. The present disclosure further provides a method of improving cycling life of a sodium-sulfur cell, wherein the sodium-sulfur cell comprising a sodium anode, a sulfur cathode, and an electrolyte containing a sodium salt dispersed in an alkyl carbonate solvent.Type: GrantFiled: October 26, 2020Date of Patent: January 16, 2024Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Vipin Kumar, Zhi Wei Seh
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Patent number: 11873719Abstract: A gas-liquid spray dust settlement system for a fully mechanized mining face includes an atomization humidification subsystem, a boundary mist curtain subsystem, and a dust mist recycling subsystem that are all arranged outside the fully mechanized mining face, where the boundary mist curtain subsystem includes high-pressure blade nozzles mounted to hydraulic supports. The atomization humidification subsystem includes a spray dust settler mounted to a rocker arm of a coal cutter and configured to spray water mist completely covering the high-pressure blade nozzle. The dust mist recycling subsystem includes a wind-water linkage dust remover mounted to a semi-encircling support base, arranged under the spray dust settler, and configured to collect the water mist sprayed by the spray dust settler.Type: GrantFiled: July 14, 2020Date of Patent: January 16, 2024Assignees: ANHUI UNIVERSITY OF SCIENCE AND TECHNOLOGY, PINGAN COAL MINING ENGINEERING RESEARCH INSTITUTE CO., LTD.Inventors: Liang Yuan, Qinghua Chen, Bingyou Jiang, Jinwei Qiu, Mingyun Tang, Bo Ren, Mingqing Su
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Patent number: 11872215Abstract: Compounds, compositions, and methods are provided for covalently linking an antibody or an antibody fragment to a cargo molecule, such as a therapeutic or a diagnostic agent, using a combination of enzymatic glycan remodeling and click chemistry. The method allows a cargo molecule to be selectively and efficiently attached post-translationally to an antibody or an antibody fragment. Also provided are antibody drug conjugates, methods of making, and uses thereof.Type: GrantFiled: January 22, 2021Date of Patent: January 16, 2024Assignee: University of Georgia Research Foundation, Inc.Inventor: Geert-Jan Boons
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Patent number: 11877323Abstract: The present disclosure provides a random access method, a UE and a network side device. The random access method includes: initiating random access on one or more SS blocks; and sending random access information on each SS block to the network side device.Type: GrantFiled: April 30, 2019Date of Patent: January 16, 2024Assignees: China Mobile Communication Co., Ltd Research Institute, China Mobile Communications Group Co., Ltd.Inventors: Liang Liu, Yang Liu, Nan Hu, Nan Li
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Patent number: 11872172Abstract: A movement system for use with an overhead patient lift system includes a motor. A drum is operatively coupled to the motor. The drum is configured to be selectively driven by the motor to rotate in one of a clockwise direction and a counter-clockwise direction. A lifting strap is coupled to the drum. The lifting strap is extendable and retractable with respect to a carriage of the overhead patient lifting system as the drum rotates. A manual release operatively coupled to the drum is actuatable to selectively disengage the drum from the motor to allow the lifting strap to be manually extended. Also disclosed is an overhead patient lift system including the movement system and a method for manually extending a lifting strap of an overhead patient lift system.Type: GrantFiled: February 21, 2020Date of Patent: January 16, 2024Assignee: LIKO RESEARCH & DEVELOPMENT ABInventors: Mattias Andersson, Roger Karlsson, Andreas Gelfgren
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Patent number: 11874358Abstract: A system and method are provided for controlling a magnetic resonance imaging (MRI) system. The method includes performing a gradient echo pulse sequence that includes a phase increment of an RF pulse of the gradient echo pulse sequence selected to encode diffusion information into a phase of MR signals. The method also includes controlling the plurality of gradient coils and the RF system to acquire the MR signals as MR data, processing the MR data to determine MR signals corresponding to diffusion in the subject when acquiring the MR signals, and generating at least one of an image or a map of the subject indicating the diffusion in the subject from the MR data.Type: GrantFiled: March 15, 2022Date of Patent: January 16, 2024Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Daiki Tamada, Scott B. Reeder
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Patent number: 11873341Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25, in particular an anti CD25-a-674 antibody which do not block the binding of CD25 to IL-2 or IL-2 signalling. The claimed antibody binds to the epitopes: YQCVQGYRALHRGP (150 to 163) or SVCKMTHGKTRWTQP (166 to 180) on CD25 Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical compositions and methods of treatment, in particular for treating cancer.Type: GrantFiled: March 13, 2019Date of Patent: January 16, 2024Assignees: Tusk Therapeutics Ltd., Cancer Research Technology LimitedInventors: Anne Goubier, Beatriz Goyenechea Corzo, Josephine Salimu, Kevin Moulder, Pascal Merchiers, Sergio Quezada
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Patent number: 11873214Abstract: A method for fabricating nano-electro-mechanical tags for identification and authentication includes, in part, forming a protective layer above a substrate, forming a first conductive layer above the protective layer serving as a first electrode, forming a piezoelectric layer above the first conductive layer, forming a second conductive layer above the piezoelectric layer, patterning the second conductive layer to form a second electrode, patterning the piezoelectric layer to expose one or more portions of the first conductive layer, and forming one or more trenches that extends into a plurality layers formed above. In addition, a sacrificial layer can be formed above portions of the substrate, and the sacrificial layer can be removed by etching to release the nano-electro-mechanical tags from the substrate.Type: GrantFiled: January 19, 2021Date of Patent: January 16, 2024Assignee: University of Florida Research Foundation, IncorporatedInventors: Roozbeh Tabrizian, Swarup Bhunia
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Patent number: 11871908Abstract: A disposable speculum for an otoscope provides a sheath adapted to cover an elongate otoscope probe and providing inwardly extending tabs that are adapted to flex outward when the speculum is inserted over the otoscope to engage corresponding grooves of the otoscope. The inwardly extending tabs provide precise alignment of the speculum with the elongate otoscope probe along an insertion axis to protect a length of the probe.Type: GrantFiled: February 4, 2021Date of Patent: January 16, 2024Assignee: Wisconsin Alumni Research FoundationInventors: James Berbee, Greg Rebella, Azita Hamedani, Patrick Ayerle, Thomas Hutcheson, IV, Ralph Paul
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Patent number: 11874074Abstract: A shape-morphing fin includes a fixed portion, a multistable portion, a coupling portion, and a vibration source. The multistable portion functions as a negative stiffness element. The multistable portion is selectively movable between a first position and a second position. The movement between first position and the second position is configured to remove the ice formation from the structure. The coupling portion couples the fixed portion to the multistable portion. The vibration source is configured to produce a resonant vibration to engage the movement of the multistable portion from the first position to the second position.Type: GrantFiled: July 1, 2022Date of Patent: January 16, 2024Assignee: Purdue Research FoundationInventors: William Travis Horton, Andres Arrieta Diaz, James Edward Braun