Abstract: The subject invention concerns materials and methods for culture of cell aggregates. The subject invention utilizes three-dimensional (3-D) inserts comprising micro-channels having selected dimensions. The inserts are provided in or on tissue culture plates that can be supported on a programmable rocking platform/station, thereby providing for a hydrodynamic environment that promotes 3-D aggregation of cells cultured on the plates. The supporting rocker is programmed to provide motion that generates hydrodynamic conditions that support 3-D cell aggregation and long-term culture. The subject invention also concerns an apparatus comprising a tissue culture vessel that comprises a 3-D insert of the present invention, and a programmable rocking platform/station that can provide motion to the vessel provided thereon, thereby generating hydrodynamic conditions and wave motion that support 3-D cell aggregation and cell culture. The subject invention also concerns methods for growing 3-D aggregates of cells.

Abstract: A method for fabricating nano-electro-mechanical tags for identification and authentication includes, in part, forming a protective layer above a substrate, forming a first conductive layer above the protective layer serving as a first electrode, forming a piezoelectric layer above the first conductive layer, forming a second conductive layer above the piezoelectric layer, patterning the second conductive layer to form a second electrode, patterning the piezoelectric layer to expose one or more portions of the first conductive layer, and forming one or more trenches that extends into a plurality layers formed above. In addition, a sacrificial layer can be formed above portions of the substrate, and the sacrificial layer can be removed by etching to release the nano-electro-mechanical tags from the substrate.

Abstract: Provided is a terahertz light source device including an antenna, a plurality of wire electrodes configured to connect the antenna to a power source, a capacitor connected to the wire electrodes between the antenna and the power source, and a plurality of resonance tunneling diodes connected to the wire electrodes between the capacitor and the antenna, and configured to generate a terahertz wave by coupling with the capacitor as a parallel resonance circuit with respect to the power source.

Abstract: Compounds, compositions, and methods are provided for covalently linking an antibody or an antibody fragment to a cargo molecule, such as a therapeutic or a diagnostic agent, using a combination of enzymatic glycan remodeling and click chemistry. The method allows a cargo molecule to be selectively and efficiently attached post-translationally to an antibody or an antibody fragment. Also provided are antibody drug conjugates, methods of making, and uses thereof.

Abstract: A movement system for use with an overhead patient lift system includes a motor. A drum is operatively coupled to the motor. The drum is configured to be selectively driven by the motor to rotate in one of a clockwise direction and a counter-clockwise direction. A lifting strap is coupled to the drum. The lifting strap is extendable and retractable with respect to a carriage of the overhead patient lifting system as the drum rotates. A manual release operatively coupled to the drum is actuatable to selectively disengage the drum from the motor to allow the lifting strap to be manually extended. Also disclosed is an overhead patient lift system including the movement system and a method for manually extending a lifting strap of an overhead patient lift system.

Abstract: A system and method are provided for controlling a magnetic resonance imaging (MRI) system. The method includes performing a gradient echo pulse sequence that includes a phase increment of an RF pulse of the gradient echo pulse sequence selected to encode diffusion information into a phase of MR signals. The method also includes controlling the plurality of gradient coils and the RF system to acquire the MR signals as MR data, processing the MR data to determine MR signals corresponding to diffusion in the subject when acquiring the MR signals, and generating at least one of an image or a map of the subject indicating the diffusion in the subject from the MR data.

Abstract: Various embodiments relate to an FTIR-based diffractive optical structure, and a waveguide device and an augmented reality display each including same. The augmented reality display may comprise: a projector configured to provide light related to an image; and a waveguide device for outputting at least a part of the light, wherein: the waveguide device comprises a waveguide and a diffractive optical structure disposed on one surface of the waveguide; and the diffractive optical structure comprises an expansion grating disposed at the one surface of the waveguide and an output grating disposed along the axis perpendicular to the one surface of the waveguide and overlapping at least a partial area of the expansion grating.

Abstract: Skin patch sensors for monitoring and/or affecting body parameters, with alignment, positioning and attachment using magnets. The repeated use of releasable adhesive layers to retain skin patch sensors on skin can cause skin irritation, which can be reduced by rotating a skin patch between attachment times around a magnetically coupled pivot point. Skin patch sensors can be configured with internal coils to inductively couple to external power transmitting and communications coils with solenoids in anti-Helmholtz configurations.

Abstract: Methods and systems are described for detecting the likelihood of patent ductus arteriosus (PDA) in an infant using electrocardiogram and photoplethysmographic pulse signals obtained from the upper body and foot of the infant.

Abstract: A gas-liquid spray dust settlement system for a fully mechanized mining face includes an atomization humidification subsystem, a boundary mist curtain subsystem, and a dust mist recycling subsystem that are all arranged outside the fully mechanized mining face, where the boundary mist curtain subsystem includes high-pressure blade nozzles mounted to hydraulic supports. The atomization humidification subsystem includes a spray dust settler mounted to a rocker arm of a coal cutter and configured to spray water mist completely covering the high-pressure blade nozzle. The dust mist recycling subsystem includes a wind-water linkage dust remover mounted to a semi-encircling support base, arranged under the spray dust settler, and configured to collect the water mist sprayed by the spray dust settler.

Abstract: A corner bracket may include first and second retainers configured to receive respective ends of first and second frame members, such that the first and second frame members are substantially perpendicular with respect to one another. The first and second retainers may include structural and sealing portions, wherein the structural portion includes a first material and the sealing portion includes a second material, with the first material being relatively more rigid than the second material, and the second material being relatively more elastic than the first material. The corner bracket may also include first and second exterior surfaces at least partially including the second material and first and second door panel interfaces configured to provide a seal between the first and second exterior surfaces and interior surfaces of first and second door panels in a closed position. The corner bracket may be incorporated into a frame for a cabinet.

Abstract: Bacterial cultures are provided that comprise a modified Pseudomonas aeruginosa bacterium missing or deficient in two or more virulence factors. The two or more virulence factors can be selected from exotoxin A, hemolytic phospholipase C, phenazine-specific methyltransferase, alpha-1,3-rhamnosyltransferase, and 3-phosphoshikimate 1-carboxyvinyltransferase. Certain of the modified Pseudomonas aeruginosa bacteria are also missing or deficient in one or more alginate acetylation enzymes including the alginate Oacetyltransferases AlgI, AlgJ, AlgF, AlgX, and/or the C5-mannuronan epimerase AlgG. Methods of producing alginate are also provided along with compositions comprising alginate produced by the modified Pseudomonas aeruginosa bacteria.

Abstract: The present disclosure relates to the co-expression of an endonuclease with an end-processing enzyme for the purpose of enhanced processing of the polynucleotide ends generated by endonuclease cleavage.

Abstract: An igniter system and method for igniting a propellant by an optical energy source. The igniter system including an igniter composite and a propellant. The igniter composite including a reactive component and a fluoropolymer. The propellant is coupled to the igniter composite. The igniter composite has a composition including nano-aluminum at ideal stoichiometry in polyvinylidene fluoride. The igniter composite is configured to achieve a sustained ignition from a wavelength emitted from the optical energy source. The wavelength is between around 250 nanometers to around 1100 nanometers.

Abstract: The present disclosure relates to an electrolyte comprising: a) a sodium salt; b) an additive comprising at least one additional metallic/metalloid cation having a standard reduction potential which is at least 2.5V more positive than that of sodium cation; wherein said sodium salt and said additive are dispersed in a solvent comprising at least one alkyl carbonate, and wherein the concentration of said metallic/metalloid cation in the electrolyte is 15 mM to 250 mM. The present disclosure also relates to a sodium-sulfur cell comprising a sodium anode, a microporous sulfur cathode, and the electrolyte as described herein. The present disclosure further provides a method of improving cycling life of a sodium-sulfur cell, wherein the sodium-sulfur cell comprising a sodium anode, a sulfur cathode, and an electrolyte containing a sodium salt dispersed in an alkyl carbonate solvent.

Abstract: The present invention relates generally to a therapeutic protocol for treating a subject having cancer. Taught herein is a method of treating cancer or reducing the risk of recurrence of cancer in a subject following an anti-cancer therapy.

Abstract: The invention generally relates to systems and methods for quantifying an analyte extracted from a sample. In certain embodiments, the invention provides methods that involve introducing a solvent into a capillary, introducing the capillary into a vessel including a sample such that a portion of the sample is introduced into the capillary, moving the sample and the solvent within the capillary to induce circulation within the sample and the solvent, thereby causing the analyte to be extracted from the sample and into the solvent, analyzing the analyte that has been extracted from the sample, and quantifying the analyte. In certain embodiments, the quantifying step is performed without knowledge of a volume of the sample and/or solvent.

Abstract: An encoding/decoding apparatus and method for controlling a channel signal is disclosed, wherein the encoding apparatus may include an encoder to encode an object signal, a channel signal, and rendering information for the channel signal, and a bit stream generator to generate, as a bit stream, the encoded object signal, the encoded channel signal, and the encoded rendering information for the channel signal.

Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.