Abstract: A packaging structure includes: a substrate provided with a through-cavity penetrating up and down, and a metal heat sink on a front surface of the substrate; a bonding chip mounting area and a first passive element mounting area on the front surface, and a flip chip mounting area, a second passive element mounting area and a pin lead mounting area are provided on a back surface of the substrate; a first sealing ring located at the periphery of the bonding chip mounting area and the first passive element mounting area; a first cover plate packaged on the first sealing ring; a second sealing ring located at the periphery of the flip chip mounting area and the second passive element mounting area with the pin lead mounting area being located at the periphery of the second sealing ring; and a second cover plate packaged on the second sealing ring.

Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to 5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluoromethyl)-2-pyridyl]amino]pyrazine-2-carbonitrile compounds (referred to herein as “TFM compounds”) which, inter alia, inhibit Checkpoint Kinase 1 (CHK1) kinase function. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit CHK1 kinase function, and in the treatment of diseases and conditions that are mediated by CHK1, that are ameliorated by the inhibition of CHK1 kinase function, etc., including proliferative conditions such as cancer, etc.

Abstract: A method and an apparatus for generating a secret key for encrypted communication using a synchronized neural network, which includes: generating initial codewords based on a bit string of weight values of the synchronized neural network and transmitting a first partial codeword of the initial codewords to a device of another party; receiving a second partial codeword generated by the device of the other party and combining final codewords based on the second partial codeword received from the device of the party and the bit string of the weight values; performing an error correction on the combined final codewords and transmitting first restoration success information according to the error correction to the device of the other party; and receiving second restoration success information from the device of the other party and generating the secret key based on the restoration success information of the device of the other party, are provided.

Abstract: An automatic dry fire protection sprinkler assembly and method of operation. The sprinkler assembly includes an elongate tubular outer housing having a fluid discharge end with an outlet opening, an internal channel and a contact surface proximate the outlet opening. A fluid deflection member is coupled to the housing at a preferably fixed distance from the outlet opening. An internal fluid control assembly includes an ejectable member that is ejected out the outlet opening and displaced out of the fluid flow path between the housing and the fluid deflection member. Upon sprinkler actuation, the fluid control assembly engages the internal channel to axially guide the fluid control assembly and prevent rotation of the fluid control assembly about the sprinkler axis. A surface contact between the ejectable member and the internal shelf causes the ejectable member to pivot clear of the sprinkler housing and the fluid deflection member.

Abstract: A GAPDH nucleic acid detection kit includes a primer set for detecting GAPDH nucleic acid. The primer set for detecting GAPDH nucleic acid includes a forward inner primer for GAPDH nucleic acids, a forward outer primer for GAPDH nucleic acids, a backward inner primer for GAPDH nucleic acids and a backward outer primer for GAPDH nucleic acids. The primer set for detecting GAPDH nucleic acid is used in a loop-mediated isothermal amplification (LAMP).

Abstract: Systems and methods for synchronizing subunits a multi-unit power distribution network contemplate selectively opening and closing a switch at the power source to disconnect and reconnect the power source to power conductors to send a synchronization signal to one or more remote subunits. Once the remote subunits are synchronized and able to disconnect from the power conductors, leak detection at the power source may be enabled to detect inadvertent loads on the power conductors (e.g., a human touching the power conductors). Further, the remote subunits may power off and on based on the synchronization signal thereby ensuring that an end device may receive power concurrently from multiple remote subunits so as to meet the power requirements of the end device. Enabling the leak detection improves the safety features of the power distribution network and synchronized power delivery to the end device prevents improper shut downs.

Abstract: Provided is a vibration power generation element that can have improved property of piezoelectricity and mechanical robustness, while having a reduced cost. A piezoelectric layer (20) is formed on a substrate (10), which is supported on a support member (11) in a cantilever state, with a dielectric layer (102) interposed there between. A pair of comb electrodes (41, 42) are formed on the piezoelectric layer (20) that include comb portions (412, 422) extending in a direction (i.e., transverse direction) perpendicular to the extension direction (i.e., longitudinal direction) of the substrate 10 and disposed so as to be fitted into one another.

Abstract: A movement control method for a multi-vehicle system for moving multiple vehicles to target positions individually set for the vehicles includes: acquiring first positions of the vehicles; determining control input for moving the vehicles from the first positions to second positions away from the target positions by a first distance or more while the vehicles satisfy a predetermined condition; and updating the first distance to be a shorter distance when a distance between the second position and the target position of each of the vehicles becomes equal to or more than the first distance and within an updating distance.

Abstract: A thread collecting method for easily and simply collecting a bagworm-derived pure silk thread from a bagworm with a small number of processes and a thread collecting device for implementing the thread collecting method are developed and provided. A device that collects a silk thread from a bagworm is provided, the device including: a container that accommodates the bagworm; and an in-and-out hole through which the bagworm is put in and taken out of the container. A width of a maximum short axis cross section of an inner space of the container is in a range from 1.2 times or more to less than 3.1 times relative to a maximum body width of the bagworm being accommodated.

Abstract: The present disclosure provides antibody sequences found in antibodies that bind to human CD25. In particular, the present disclosure provides sequences of anti-human CD25 antibodies, which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical composition and methods of treatment, in particular for treating cancer.

Abstract: The present invention provides for polycrystalline superconducting permanent magnets which are synthesized of doped superconducting (AE) Fe2As2 compounds, where AE denotes an alkaline earth metal, such as Ba, Sr, Mg or Ca. The superconducting permanent magnets of the present invention can be magnetized in their superconducting state by induced currents, resulting in trapped magnetization that scales with the size of the bulk material. The magnitude of the trapped field has been demonstrated to be over 1 T and is predicted to be over 10 T if the technology is scaled, which is much higher than the capabilities of permanent magnets and other superconducting polycrystalline bulks currently known in the art.

Abstract: The present disclosure relates to novel ?-opioid receptor agonists, and the method of making and using the novel ?-opioid receptor agonists. The novel ?-opioid receptor agonists are selective ?-opioid receptor agonists that have substantially no beta-arrestin 2 recruitment or low beta-arrestin 2 recruitment. The novel ?-opioid receptor agonists may be used for the treatment for alcohol use disorders and other co-occurring psychiatric disorders.

Abstract: A compressor system for receiving a gas fluid and discharging the gas fluid at a higher pressure. The system comprises at least one compressor and at least one piston intensifier associated with each compressor. Each piston intensifier has a double-acting piston, with one piston head reciprocating in an actuation cavity and the other piston head reciprocating in a high pressure cavity. The compressor delivers its output flow to both cavities of the piston intensifier, alternating between below and above their piston heads, to provide both a working (actuation) fluid and a fluid to be compressed and discharged. A return flow from the actuation cavity back to the compressor also alternates to recycle the working fluid.

Abstract: An optical fiber drop cable including a cable jacket having an outer surface defining the outermost surface of the optical fiber drop cable. The optical fiber drop cable also includes a subunit, a first strength element, and a second strength element. The first strength element, the second strength element, and the subunit are embedded in the cable jacket, and the first strength element, the second strength element, and the subunit are arranged substantially parallel to each other on a first plane. The subunit includes a buffer tube having an inner surface and an outer surface, at least one optical fiber, and a plurality of strengthening yarns. The plurality of strengthening yarns are disposed between the inner surface of the buffer tube and the at least one optical fiber, and the outer surface of the buffer tube is at least partially in contact with the cable jacket.

Abstract: A vacuum assisted pressure swing adsorption device for purifying oxygen from air, comprising: a first adsorption bed of LiLSX adsorbent and second adsorption bed of AgLiLSX adsorbent, wherein the first adsorption bed and the second adsorption bed are connected to each other in series. A method for producing medical oxygen using a vacuum assisted pressure swing adsorption device comprising: a first adsorption bed of LiLSX adsorbent and second adsorption bed of AgLiLSX adsorbent, wherein the first adsorption bed and the second adsorption bed are connected to each other in series.

Abstract: The present disclosure provides a method for object detection and recognition based on a neural network. The method includes: adding a detection layer following three detection layers of an existing YOLOv5 network model, to construct a new YOLOv5 network model; then, training the new YOLOv5 network model by considering an overlapping area between a predicted box and a ground truth box, a center-to-center distance between the two boxes, and an aspect ratio of the two boxes; and finally, inputting a to-be-detected image into the trained new YOLOv5 network model, outputting a predicted box of an object and probability values corresponding to a class to which the object belongs, and setting a class corresponding to a maximum probability value as a predicted class of the object in the to-be-detected image. This method can quickly and effectively detect multiple classes of objects. Especially, a detection effect for small objects is more ideal.

Abstract: A package substrate includes a substrate, an interposer and an insulating protective layer. The substrate has a first surface and a second surface opposing to the first surface. The first surface includes a plurality of first conductive pads. The interposer is disposed on the first surface of the substrate such that the first conductive pads are partially covered by the interposer. The interposer includes a plurality of penetrating conductive vias electrically connected to the substrate. The insulating protective layer is disposed on the first surface of the substrate and surrounding the interposer. The insulating protective layer includes at least one penetrating conductive column, wherein a first width of the respective penetrating conductive column is greater than a second width of each of the penetrating conductive vias of the interposer.

Abstract: An inlet duct for use with an engine is presented. The invention includes a duct structure, at least one spike disposed along an interior surface of the duct structure, and an inlet throat formed by one or more apexes disposed along an equal number of spikes. The inlet throat corresponds to the minimum cross-sectional area through which airflow passes as otherwise allowed by the maximal obstruction formed by the apex(es) within the duct structure. Each spike is bounded by a longitudinal ridge and a lateral ridge along an upper end and a base along a lower end. The longitudinal ridge and the lateral ridge intersect at the apex. In preferred embodiments, the longitudinal ridge is at least partially non-linear so as to properly conform to the interior surface of the duct structure. The portion of each spike upstream of the inlet throat functions primarily as a supersonic diffuser. The portion of each spike downstream of the inlet throat functions primarily as a subsonic diffuser.

Abstract: The invention relates to therapeutic compositions comprising at least one isolated bacterium and a pharmaceutically acceptable excipient, as well as methods of preparing such therapeutic compositions. The therapeutic compositions find application in the treatment of dysbiosis, in particular dysbiosis of the gastrointestinal tract.

Abstract: A device (10) for guiding a pivoting mass in rotary pivoting, in particular for a horological movement comprising, arranged in series substantially in the same plane, a first support (2), a first pair of uncrossed strips (5, 6), a second support (3), a pair of crossed strips (7, 8), and a third support (4), the pair of uncrossed strips including, a first (5) and a second (6) flexible strip connecting the first support (2) to the second support (3) without crossing each other, the pair of crossed strips including a third (7) and a fourth (8) flexible strip connecting the second support (3) to the third support (4), the third (7) and fourth (8) flexible strips crossing each other between the second (3) and the third (4) support.